ZA747820B - Isoquinoline derivatives and processes for their preparation - Google Patents

Isoquinoline derivatives and processes for their preparation

Info

Publication number
ZA747820B
ZA747820B ZA00747820A ZA747820A ZA747820B ZA 747820 B ZA747820 B ZA 747820B ZA 00747820 A ZA00747820 A ZA 00747820A ZA 747820 A ZA747820 A ZA 747820A ZA 747820 B ZA747820 B ZA 747820B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Application number
ZA00747820A
Other languages
English (en)
Inventor
K Becker
H Schliep
W Mehrhof
R Pohlke
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA747820B publication Critical patent/ZA747820B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
ZA00747820A 1973-12-10 1974-12-09 Isoquinoline derivatives and processes for their preparation ZA747820B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2361390A DE2361390A1 (de) 1973-12-10 1973-12-10 Isochinolinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA747820B true ZA747820B (en) 1975-12-31

Family

ID=5900348

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00747820A ZA747820B (en) 1973-12-10 1974-12-09 Isoquinoline derivatives and processes for their preparation

Country Status (18)

Country Link
US (1) US3985881A (xx)
JP (1) JPS5088077A (xx)
AT (1) AT351026B (xx)
BE (1) BE823027A (xx)
CA (1) CA1053675A (xx)
CH (1) CH605776A5 (xx)
CS (1) CS188933B2 (xx)
DD (1) DD115666A5 (xx)
DE (1) DE2361390A1 (xx)
DK (1) DK137007C (xx)
ES (1) ES432716A1 (xx)
FR (1) FR2253522B1 (xx)
GB (1) GB1447611A (xx)
HU (1) HU171483B (xx)
IL (1) IL46160A0 (xx)
NL (1) NL7416050A (xx)
SE (1) SE7415247L (xx)
ZA (1) ZA747820B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2504250A1 (de) * 1975-02-01 1976-08-05 Merck Patent Gmbh Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung
US4232160A (en) * 1978-10-18 1980-11-04 Miles Laboratories, Inc. Isoquinoline propionamides exhibiting analgesic properties
US4556712A (en) * 1981-05-20 1985-12-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines
GB8601796D0 (en) * 1986-01-24 1986-02-26 Zambeletti Spa L Compounds
DE3713743A1 (de) * 1987-04-24 1988-11-17 Boehringer Ingelheim Kg Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE97893T1 (de) * 1988-02-19 1993-12-15 Smithkline Beecham Farma 1,2,3,4-tetrahydroisoquinoline, verfharen zu ihrer herstellung und ihre verwendung als kappa- rezeptor agonisten.
KR890012970A (ko) * 1988-02-23 1989-09-20 추후보충 테트라히드로 이소퀴놀린 유도체
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
GB8916395D0 (en) * 1989-07-18 1989-09-06 Zambeletti Spa L Pharmaceuticals
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
GB0225884D0 (en) * 2002-11-06 2002-12-11 Glaxo Group Ltd Novel compounds
MX2015008052A (es) * 2012-12-21 2016-08-18 Epizyme Inc Inhibidores de prmt5 y sus usos.
AU2016316436B2 (en) * 2015-09-01 2021-04-29 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
CA3001857A1 (en) * 2015-10-14 2017-04-20 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use against stress granules
CN111108105B (zh) 2017-09-22 2023-03-31 朱比兰特埃皮帕德有限公司 作为pad抑制剂的杂环化合物
SG11202003463XA (en) 2017-10-18 2020-05-28 Jubilant Epipad LLC Imidazo-pyridine compounds as pad inhibitors
CA3080677A1 (en) 2017-11-06 2019-05-09 Jubilant Prodel LLC Pyrimidine derivatives as inhibitors of pd1/pd-l1 activation
IL274762B2 (en) 2017-11-24 2023-10-01 Jubilant Episcribe Llc Novel heterocyclic compounds as PRMT5 inhibitors
SG11202008950PA (en) 2018-03-13 2020-10-29 Jubilant Prodel LLC Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2612503A (en) * 1949-04-19 1952-09-30 Smith Kline French Lab Basic ether-substituted isoquinolines
US2640829A (en) * 1950-11-10 1953-06-02 Smith Kline French Lab Isoquinolyl heterocyclic ethers
US3021331A (en) * 1959-07-20 1962-02-13 Pfizer & Co C Azabenzopyridocolines
US3483206A (en) * 1967-12-15 1969-12-09 Ciba Geigy Corp N-isoquinolylalkanoyl-n-arylamines
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils

Also Published As

Publication number Publication date
AU7625774A (en) 1976-06-10
HU171483B (hu) 1978-01-28
PL93405B1 (xx) 1977-05-30
DE2361390A1 (de) 1975-06-19
JPS5088077A (xx) 1975-07-15
IL46160A0 (en) 1975-02-10
DD115666A5 (xx) 1975-10-12
CH605776A5 (xx) 1978-10-13
NL7416050A (nl) 1975-06-12
CS188933B2 (en) 1979-03-30
DK137007C (da) 1978-06-05
DK639674A (xx) 1975-08-11
SE7415247L (xx) 1975-06-11
ATA981974A (de) 1978-12-15
US3985881A (en) 1976-10-12
AT351026B (de) 1979-07-10
DK137007B (da) 1978-01-02
FR2253522B1 (xx) 1978-06-30
BE823027A (fr) 1975-06-06
ES432716A1 (es) 1977-03-01
GB1447611A (en) 1976-08-25
FR2253522A1 (xx) 1975-07-04
CA1053675A (en) 1979-05-01

Similar Documents

Publication Publication Date Title
HK98589A (en) Vitamin d derivatives and process for their preparation
IL46160A0 (en) Isoquinoline derivatives and processes for their preparation
IL45158A0 (en) Piperazinyl-quinoxalines,derivatives and processes for their preparation
IL42219A0 (en) 14-hydroxymorphinan derivatives and processes for their preparation
CY969A (en) 2-anilino-nicotinic and derivatives
ZA744240B (en) Clycoluril derivatives and preparation thereof
GB1484717A (en) Isoquinoline derivatives and process for preparing them and pharmaceutical preparations comprising them
ZA742955B (en) Triazolo isoquinoline derivatives
ZA748082B (en) Derivatives of 1-phenoxy-3-aminopropan-2-01 and processes for their preparation
IL44978A0 (en) Triazolo isoquinoline derivatives
IL46423A (en) 5:6-benzo-y-pyrone derivatives and process for their preparation
IL45603A0 (en) 7-trichloroacetamido-3-desacetoxy-cephalosporanic acid derivatives and processes for their preparation
ZA74247B (en) Xanthene derivatives and processes for their preparation
ZA744425B (en) Dibenzoxepin derivatives and process for the preparation thereof
IL45083A (en) Diamino-benzophenones and process for the preparation thereof
IL45602A0 (en) 6-trichloroacetamido-penicillanic acid derivatives and processes for their preparation
AU485257B2 (en) Isoquinoline derivatives and processes for their preparation
ZA748139B (en) Propenylbenzene derivatives and processes for their preparation
IL45605A0 (en) 7-monochloroacetamido-3-desacetoxy-cephalosporanic acid derivatives and processes for their preparation
ZA748083B (en) Derivatives of 1-phenoxy-3-aminopropan-2-01 and processes for their preparation
ZA744466B (en) Piperazinyl-quinoxalines, derivatives and processes for their preparation
IL45386A0 (en) Streptamine derivatives and process for their preparation
IE40448B1 (en) Azabicycloalkanes and processes for their preparation
HK62978A (en) Diphenoxyacetic acid derivatives and processes for their preparation
IL45604A0 (en) 6-monochloroacetamido-penicillanic acid derivatives and processes for their preparation