DK127600B - Fremgangsmåde til fremstilling af terapeutisk aktive 3-substituerede 2H-1,4-benzodiazepin-2-oner. - Google Patents

Fremgangsmåde til fremstilling af terapeutisk aktive 3-substituerede 2H-1,4-benzodiazepin-2-oner.

Info

Publication number
DK127600B
DK127600B DK377762AA DK377762A DK127600B DK 127600 B DK127600 B DK 127600B DK 377762A A DK377762A A DK 377762AA DK 377762 A DK377762 A DK 377762A DK 127600 B DK127600 B DK 127600B
Authority
DK
Denmark
Prior art keywords
benzodiazepin
ones
substituted
preparation
therapeutically active
Prior art date
Application number
DK377762AA
Other languages
Danish (da)
English (en)
Inventor
S Bell
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Priority to DK201273A priority Critical patent/DK131723C/da
Publication of DK127600B publication Critical patent/DK127600B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00—Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/06—Catalysts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00—Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/18—Copolymerisation of aldehydes or ketones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00—Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/18—Copolymerisation of aldehydes or ketones
    • C08G2/22—Copolymerisation of aldehydes or ketones with epoxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polyethers (AREA)
DK377762AA 1961-08-29 1962-08-28 Fremgangsmåde til fremstilling af terapeutisk aktive 3-substituerede 2H-1,4-benzodiazepin-2-oner. DK127600B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK201273A DK131723C (da) 1961-08-29 1973-04-12 Analogifremgangsmade til fremstilling af 3-substituerede 2h-1,4-benzodiazepin-2-oner

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13456961A 1961-08-29 1961-08-29
US17717462A 1962-03-05 1962-03-05
US37974064A 1964-07-01 1964-07-01

Publications (1)

Publication Number Publication Date
DK127600B true DK127600B (da) 1973-12-03

Family

ID=27384605

Family Applications (2)

Application Number Title Priority Date Filing Date
DK377762AA DK127600B (da) 1961-08-29 1962-08-28 Fremgangsmåde til fremstilling af terapeutisk aktive 3-substituerede 2H-1,4-benzodiazepin-2-oner.
DK322265AA DK114514B (da) 1961-08-29 1965-06-25 Fremgangsmåde til fremstilling af højmolekylære, formbare oxymethylencopolymere.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK322265AA DK114514B (da) 1961-08-29 1965-06-25 Fremgangsmåde til fremstilling af højmolekylære, formbare oxymethylencopolymere.

Country Status (16)

Country Link
US (1) US3435005A (fi)
BE (2) BE666274A (fi)
BR (1) BR6242421D0 (fi)
CA (1) CA963004A (fi)
CH (4) CH467790A (fi)
CY (2) CY386A (fi)
DE (8) DE1795553C3 (fi)
DK (2) DK127600B (fi)
FI (4) FI46072C (fi)
FR (1) FR2217M (fi)
GB (5) GB1022642A (fi)
IL (1) IL23813A (fi)
LU (1) LU48964A1 (fi)
MY (3) MY6900345A (fi)
NL (1) NL6508496A (fi)
SE (5) SE335734B (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154973B (da) * 1978-12-18 1989-01-16 Gerot Pharmazeutika Fremgangsmaade til fremstilling af 3-hydroxy-1,4-benzodiazepin-2-oner

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL261058A (fi) * 1960-05-19
DE1295563B (de) * 1963-05-29 1969-05-22 American Home Prod Verfahren zur Herstellung von 5-Phenyl-7-chlor-1, 2-dihydro-3H-1, 4-benzodiazepinon-(2)-4-oxyd
BE788899A (fr) * 1971-09-15 1973-01-02 Crc Ricerca Chim Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs
ES405260A1 (es) * 1972-07-28 1975-07-01 Stabilimenti Chim Farmac Riuni Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
DE2852606A1 (de) * 1977-12-14 1979-06-21 Gerot Pharmazeutika 3-di-n-propyl-acetoxy-benzodiazepin-2-one und verfahren zu deren herstellung
US4540727A (en) * 1982-10-29 1985-09-10 Raychem Corporation Polyamide compositions
IT1165588B (it) * 1983-03-23 1987-04-22 Medosan Ind Biochimi 1,4 benzodiazepine terapeuticamente attive
CA2401928A1 (en) * 2000-03-06 2001-09-13 Teva Pharmaceutical Industries Ltd. Process for preparing pure crystalline lorazepam
CN105601576A (zh) * 2016-03-18 2016-05-25 山东新华制药股份有限公司 氯甲西泮的晶型及其制备方法
UA119735C2 (uk) * 2018-12-20 2019-07-25 Анатолій Семенович Редер Фармацевтична сполука, спосіб її отримання та застосування як лікарського засобу

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2457224A (en) * 1945-07-03 1948-12-28 Du Pont Preparation of polydioxolane
BE522938A (fi) * 1951-08-22
US3027352A (en) * 1958-02-28 1962-03-27 Celanese Corp Copolymers
NL271273A (fi) * 1960-11-15
NL286742A (fi) * 1961-12-14
US3293219A (en) * 1963-07-10 1966-12-20 Tenneco Chem Polyacetal terpolymers containing randomly recurring groups derived from a methylene-bis-

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154973B (da) * 1978-12-18 1989-01-16 Gerot Pharmazeutika Fremgangsmaade til fremstilling af 3-hydroxy-1,4-benzodiazepin-2-oner

Also Published As

Publication number Publication date
SE368575B (fi) 1974-07-08
FI46849C (fi) 1973-07-10
DE1795553B2 (de) 1973-10-31
MY7000021A (en) 1970-12-31
DE1570365B2 (de) 1970-12-23
FI46848B (fi) 1973-04-02
DE1795556C3 (de) 1974-04-25
DE1795556A1 (de) 1972-01-27
FI47371C (fi) 1973-11-12
SE323080B (fi) 1970-04-27
DE1645903B2 (de) 1977-09-01
CH451519A (fr) 1968-05-15
FR2217M (fr) 1963-12-16
BE621819A (fi)
GB1022644A (en) 1966-03-16
CH467790A (de) 1969-01-31
DE1795509B2 (de) 1973-09-06
DE1795553A1 (de) 1972-02-03
DE1645904B1 (de) 1970-08-06
DE1795556B2 (de) 1973-09-13
DE1795509A1 (de) 1972-04-13
DE1445412A1 (de) 1969-02-27
CH417611A (de) 1966-07-31
GB1022645A (en) 1966-03-16
DE1570365A1 (de) 1970-01-29
CA963004A (en) 1975-02-18
DE1795509C3 (de) 1974-04-11
FI47371B (fi) 1973-07-31
BR6242421D0 (pt) 1973-07-12
US3435005A (en) 1969-03-25
SE322225B (fi) 1970-04-06
SE337033B (fi) 1971-07-26
DE1645903A1 (de) 1970-01-02
DE1795553C3 (de) 1974-07-18
NL6508496A (fi) 1966-01-03
CY386A (en) 1967-04-25
DE1645903C3 (de) 1978-05-03
SE335734B (fi) 1971-06-07
GB1078788A (en) 1967-08-09
FI46849B (fi) 1973-04-02
DE1795558A1 (de) 1971-11-18
CH446362A (de) 1967-11-15
DK114514B (da) 1969-07-07
FI46072C (fi) 1972-12-11
IL23813A (en) 1969-04-30
FI46072B (fi) 1972-08-31
LU48964A1 (fi) 1966-01-03
BE666274A (fi) 1966-01-03
MY6900345A (en) 1969-12-31
CY498A (en) 1969-07-01
GB1022642A (en) 1966-03-16
FI46848C (fi) 1973-07-10
MY6900102A (en) 1969-12-31
GB1022643A (en) 1966-03-16

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