ES405260A1 - Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas. - Google Patents

Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.

Info

Publication number
ES405260A1
ES405260A1 ES405260A ES405260A ES405260A1 ES 405260 A1 ES405260 A1 ES 405260A1 ES 405260 A ES405260 A ES 405260A ES 405260 A ES405260 A ES 405260A ES 405260 A1 ES405260 A1 ES 405260A1
Authority
ES
Spain
Prior art keywords
therepeutical
benzodiazepine compounds
acetoxy
benzodiazepin
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES405260A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STABILIMENTI CHIM FARMAC RIUNI
Original Assignee
STABILIMENTI CHIM FARMAC RIUNI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by STABILIMENTI CHIM FARMAC RIUNI filed Critical STABILIMENTI CHIM FARMAC RIUNI
Priority to ES405260A priority Critical patent/ES405260A1/es
Priority to JP8253473A priority patent/JPS5738586B2/ja
Priority to GB3541273A priority patent/GB1431282A/en
Priority to DE2338058A priority patent/DE2338058C3/de
Priority to FR7327672A priority patent/FR2194432B1/fr
Publication of ES405260A1 publication Critical patent/ES405260A1/es
Priority to BE2056783A priority patent/BE865164Q/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES405260A 1972-07-28 1972-07-28 Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas. Expired ES405260A1 (es)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ES405260A ES405260A1 (es) 1972-07-28 1972-07-28 Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
JP8253473A JPS5738586B2 (es) 1972-07-28 1973-07-19
GB3541273A GB1431282A (en) 1972-07-28 1973-07-25 Benzodiazepine compounds for therepeutical use
DE2338058A DE2338058C3 (de) 1972-07-28 1973-07-26 7-Chlor-1,3-dihydro-1-(2-hydroxyäthyl)-3-hydroxy-5-(o-fluorphenyl)-2H-1,4-benzodiazepin-2-on, dieses enthaltendes Arzneimittel und Verfahren zu seiner Herstellung
FR7327672A FR2194432B1 (es) 1972-07-28 1973-07-27
BE2056783A BE865164Q (fr) 1972-07-28 1978-03-22 Nouvelles benzodiazepines utiles notamment comme sedatifs et agents psychotropes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES405260A ES405260A1 (es) 1972-07-28 1972-07-28 Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.

Publications (1)

Publication Number Publication Date
ES405260A1 true ES405260A1 (es) 1975-07-01

Family

ID=8461826

Family Applications (1)

Application Number Title Priority Date Filing Date
ES405260A Expired ES405260A1 (es) 1972-07-28 1972-07-28 Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.

Country Status (6)

Country Link
JP (1) JPS5738586B2 (es)
BE (1) BE865164Q (es)
DE (1) DE2338058C3 (es)
ES (1) ES405260A1 (es)
FR (1) FR2194432B1 (es)
GB (1) GB1431282A (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0516825Y2 (es) * 1989-01-20 1993-05-06

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE621819A (es) * 1961-08-29
NL289735A (es) * 1962-03-09
NL301733A (es) * 1962-12-20
NL298071A (es) * 1963-06-04
DE2043614A1 (en) * 1969-09-19 1971-03-25 Gerot Pharmazeutika Dr Walter Otto KG, Wien Hydroxy benzodiazepine derivs with sedative - activity
JPS5011999B1 (es) * 1971-06-18 1975-05-08

Also Published As

Publication number Publication date
FR2194432A1 (es) 1974-03-01
JPS5738586B2 (es) 1982-08-16
DE2338058A1 (de) 1974-02-14
JPS4980086A (es) 1974-08-02
GB1431282A (en) 1976-04-07
FR2194432B1 (es) 1976-12-03
BE865164Q (fr) 1978-07-17
DE2338058B2 (de) 1980-11-06
DE2338058C3 (de) 1982-01-14

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