FI46848C - Menetelmä terapeuttisesti vaikuttavien 3-halogeeni-3H-1,2-dihydro-1,4- bentsodiatsepiini-2-onien valmistamiseksi. - Google Patents

Menetelmä terapeuttisesti vaikuttavien 3-halogeeni-3H-1,2-dihydro-1,4- bentsodiatsepiini-2-onien valmistamiseksi.

Info

Publication number
FI46848C
FI46848C FI672158A FI215867A FI46848C FI 46848 C FI46848 C FI 46848C FI 672158 A FI672158 A FI 672158A FI 215867 A FI215867 A FI 215867A FI 46848 C FI46848 C FI 46848C
Authority
FI
Finland
Prior art keywords
benzodiazepin
dihydro
halo
ones
preparation
Prior art date
Application number
FI672158A
Other languages
English (en)
Swedish (sv)
Other versions
FI46848B (fi
Inventor
Bell
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of FI46848B publication Critical patent/FI46848B/fi
Publication of FI46848C publication Critical patent/FI46848C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00—Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/06—Catalysts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00—Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/18—Copolymerisation of aldehydes or ketones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00—Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/18—Copolymerisation of aldehydes or ketones
    • C08G2/22—Copolymerisation of aldehydes or ketones with epoxy compounds
FI672158A 1961-08-29 1967-08-10 Menetelmä terapeuttisesti vaikuttavien 3-halogeeni-3H-1,2-dihydro-1,4- bentsodiatsepiini-2-onien valmistamiseksi. FI46848C (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13456961A 1961-08-29 1961-08-29
US17717462A 1962-03-05 1962-03-05
US37974064A 1964-07-01 1964-07-01

Publications (2)

Publication Number Publication Date
FI46848B FI46848B (fi) 1973-04-02
FI46848C true FI46848C (fi) 1973-07-10

Family

ID=27384605

Family Applications (4)

Application Number Title Priority Date Filing Date
FI621565A FI46072C (fi) 1961-08-29 1962-08-27 Menetelmä terapeuttisesti vaikuttavien 3-asyylioksi-3H-1,2-dihydro-1,4 -bentsodiatsepiini-2-onien valmistamiseksi.
FI672159A FI46849C (fi) 1961-08-29 1967-08-10 Menetelmä terapeuttisesti vaikuttavien 3-hydroksi-3H-1,2-dihydro-1,4-b entsodiatsepiini-2-onien valmistamiseksi.
FI672158A FI46848C (fi) 1961-08-29 1967-08-10 Menetelmä terapeuttisesti vaikuttavien 3-halogeeni-3H-1,2-dihydro-1,4- bentsodiatsepiini-2-onien valmistamiseksi.
FI682762A FI47371C (fi) 1961-08-29 1968-09-30 Menetelmä 5-aryyli-3-hydroksi-1-alempi alkyyli-1,2-dihydro-3H-1,4-bent sodiatsepiini-2-oni-johdannaisten valmistamiseksi.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
FI621565A FI46072C (fi) 1961-08-29 1962-08-27 Menetelmä terapeuttisesti vaikuttavien 3-asyylioksi-3H-1,2-dihydro-1,4 -bentsodiatsepiini-2-onien valmistamiseksi.
FI672159A FI46849C (fi) 1961-08-29 1967-08-10 Menetelmä terapeuttisesti vaikuttavien 3-hydroksi-3H-1,2-dihydro-1,4-b entsodiatsepiini-2-onien valmistamiseksi.

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI682762A FI47371C (fi) 1961-08-29 1968-09-30 Menetelmä 5-aryyli-3-hydroksi-1-alempi alkyyli-1,2-dihydro-3H-1,4-bent sodiatsepiini-2-oni-johdannaisten valmistamiseksi.

Country Status (16)

Country Link
US (1) US3435005A (fi)
BE (2) BE666274A (fi)
BR (1) BR6242421D0 (fi)
CA (1) CA963004A (fi)
CH (4) CH467790A (fi)
CY (2) CY386A (fi)
DE (8) DE1645904B1 (fi)
DK (2) DK127600B (fi)
FI (4) FI46072C (fi)
FR (1) FR2217M (fi)
GB (5) GB1022642A (fi)
IL (1) IL23813A (fi)
LU (1) LU48964A1 (fi)
MY (3) MY6900102A (fi)
NL (1) NL6508496A (fi)
SE (5) SE368575B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL261058A (fi) * 1960-05-19
DE1295563B (de) * 1963-05-29 1969-05-22 American Home Prod Verfahren zur Herstellung von 5-Phenyl-7-chlor-1, 2-dihydro-3H-1, 4-benzodiazepinon-(2)-4-oxyd
BE788899A (fr) * 1971-09-15 1973-01-02 Crc Ricerca Chim Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs
ES405260A1 (es) * 1972-07-28 1975-07-01 Stabilimenti Chim Farmac Riuni Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
FI783743A (fi) * 1977-12-14 1979-06-15 Gerot Pharmazeutika Foerfarande foer framstaellning av 3-di-n-propyl-acetoxi-benzodiazepin-2-oner
AT361492B (de) * 1978-12-18 1981-03-10 Gerot Pharmazeutika Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen
US4540727A (en) * 1982-10-29 1985-09-10 Raychem Corporation Polyamide compositions
IT1165588B (it) * 1983-03-23 1987-04-22 Medosan Ind Biochimi 1,4 benzodiazepine terapeuticamente attive
EP1265875A4 (en) * 2000-03-06 2003-07-09 Teva Pharma PROCESS FOR THE PREPARATION OF PURE CRYSTALLINE LORAZEPAM
CN105601576A (zh) * 2016-03-18 2016-05-25 山东新华制药股份有限公司 氯甲西泮的晶型及其制备方法
UA119735C2 (uk) * 2018-12-20 2019-07-25 Анатолій Семенович Редер Фармацевтична сполука, спосіб її отримання та застосування як лікарського засобу

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2457224A (en) * 1945-07-03 1948-12-28 Du Pont Preparation of polydioxolane
NL180786B (nl) * 1951-08-22 Nat Res Dev Inrichting voor het onderzoeken van monsters.
US3027352A (en) * 1958-02-28 1962-03-27 Celanese Corp Copolymers
NL271273A (fi) * 1960-11-15
BE626151A (fi) * 1961-12-14
US3293219A (en) * 1963-07-10 1966-12-20 Tenneco Chem Polyacetal terpolymers containing randomly recurring groups derived from a methylene-bis-

Also Published As

Publication number Publication date
DE1795509A1 (de) 1972-04-13
LU48964A1 (fi) 1966-01-03
DE1570365A1 (de) 1970-01-29
CY498A (en) 1969-07-01
CH417611A (de) 1966-07-31
BR6242421D0 (pt) 1973-07-12
BE621819A (fi)
FI46849B (fi) 1973-04-02
NL6508496A (fi) 1966-01-03
CH467790A (de) 1969-01-31
DK127600B (da) 1973-12-03
IL23813A (en) 1969-04-30
BE666274A (fi) 1966-01-03
MY6900102A (en) 1969-12-31
FI46848B (fi) 1973-04-02
FI47371C (fi) 1973-11-12
DE1795509B2 (de) 1973-09-06
DE1645903B2 (de) 1977-09-01
SE368575B (fi) 1974-07-08
SE322225B (fi) 1970-04-06
DE1445412A1 (de) 1969-02-27
GB1022644A (en) 1966-03-16
DE1795556B2 (de) 1973-09-13
DE1795509C3 (de) 1974-04-11
DK114514B (da) 1969-07-07
DE1645903C3 (de) 1978-05-03
SE337033B (fi) 1971-07-26
MY6900345A (en) 1969-12-31
CH446362A (de) 1967-11-15
DE1645904B1 (de) 1970-08-06
CH451519A (fr) 1968-05-15
DE1645903A1 (de) 1970-01-02
DE1570365B2 (de) 1970-12-23
FI46849C (fi) 1973-07-10
SE323080B (fi) 1970-04-27
DE1795556C3 (de) 1974-04-25
CY386A (en) 1967-04-25
DE1795553C3 (de) 1974-07-18
FI47371B (fi) 1973-07-31
FR2217M (fr) 1963-12-16
GB1022645A (en) 1966-03-16
MY7000021A (en) 1970-12-31
DE1795553A1 (de) 1972-02-03
DE1795558A1 (de) 1971-11-18
SE335734B (fi) 1971-06-07
DE1795553B2 (de) 1973-10-31
US3435005A (en) 1969-03-25
GB1022643A (en) 1966-03-16
FI46072B (fi) 1972-08-31
FI46072C (fi) 1972-12-11
GB1022642A (en) 1966-03-16
DE1795556A1 (de) 1972-01-27
CA963004A (en) 1975-02-18
GB1078788A (en) 1967-08-09

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