DK126982A - Fremgangsmaade til fremstilling af bis-estere af 1,1-alkandioler med 6beta-hydroxymethyl-penicillansyre-1,1-dioxid og en 6beta-acylaminopenicillansyre eller farmaceutisk acceptable salte deraf - Google Patents

Fremgangsmaade til fremstilling af bis-estere af 1,1-alkandioler med 6beta-hydroxymethyl-penicillansyre-1,1-dioxid og en 6beta-acylaminopenicillansyre eller farmaceutisk acceptable salte deraf Download PDF

Info

Publication number
DK126982A
DK126982A DK126982A DK126982A DK126982A DK 126982 A DK126982 A DK 126982A DK 126982 A DK126982 A DK 126982A DK 126982 A DK126982 A DK 126982A DK 126982 A DK126982 A DK 126982A
Authority
DK
Denmark
Prior art keywords
6beta
hydroxymethyl
esters
dioxide
acid
Prior art date
Application number
DK126982A
Other languages
Danish (da)
English (en)
Inventor
Michael Stephen Kellogg
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK126982A publication Critical patent/DK126982A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK126982A 1981-03-23 1982-03-22 Fremgangsmaade til fremstilling af bis-estere af 1,1-alkandioler med 6beta-hydroxymethyl-penicillansyre-1,1-dioxid og en 6beta-acylaminopenicillansyre eller farmaceutisk acceptable salte deraf DK126982A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/246,505 US4342768A (en) 1979-10-22 1981-03-23 Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Publications (1)

Publication Number Publication Date
DK126982A true DK126982A (da) 1982-09-24

Family

ID=22930958

Family Applications (1)

Application Number Title Priority Date Filing Date
DK126982A DK126982A (da) 1981-03-23 1982-03-22 Fremgangsmaade til fremstilling af bis-estere af 1,1-alkandioler med 6beta-hydroxymethyl-penicillansyre-1,1-dioxid og en 6beta-acylaminopenicillansyre eller farmaceutisk acceptable salte deraf

Country Status (26)

Country Link
US (1) US4342768A (fr)
EP (1) EP0061313B1 (fr)
JP (1) JPS57169492A (fr)
KR (1) KR860000425B1 (fr)
AT (1) ATE11291T1 (fr)
AU (1) AU527895B2 (fr)
CA (1) CA1201709A (fr)
CS (1) CS228921B2 (fr)
DD (1) DD203723A5 (fr)
DE (1) DE3261898D1 (fr)
DK (1) DK126982A (fr)
ES (1) ES8305769A1 (fr)
FI (1) FI74285C (fr)
GR (1) GR76107B (fr)
GT (1) GT198274394A (fr)
HU (1) HU186487B (fr)
IE (1) IE52812B1 (fr)
IL (1) IL65306A (fr)
NO (1) NO820897L (fr)
NZ (1) NZ200068A (fr)
PH (1) PH18040A (fr)
PL (1) PL130110B1 (fr)
PT (1) PT74624B (fr)
SU (1) SU1122230A3 (fr)
YU (1) YU61882A (fr)
ZA (1) ZA821901B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540689A (en) * 1981-09-22 1985-09-10 Kureha Kagaku Kogyo Kabushiki Kaisha Penicillin derivative
US4452796A (en) * 1982-06-14 1984-06-05 Pfizer Inc. 6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
EP0084730A1 (fr) * 1982-01-22 1983-08-03 Beecham Group Plc Esters de dérivés de pénicilline avec des inhibiteurs de bêta-lactamase, leur préparation et leur application
DE3302335A1 (de) * 1982-01-26 1983-07-28 Leo Pharmaceutical Products Ltd. A/S (Loevens kemiske Fabrik Produktionsaktieselskab), 2750 Ballerup Ss-lactamverbindungen, ihre herstellung und sie enthaltendes arzneimittel
US4462934A (en) * 1983-03-31 1984-07-31 Pfizer Inc. Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides
US4536393A (en) * 1983-06-06 1985-08-20 Pfizer Inc. 6-(Aminomethyl)penicillanic acid 1,1-dioxide esters and intermediates therefor
US4503040A (en) * 1984-02-27 1985-03-05 Pfizer Inc. 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4591459A (en) * 1984-12-03 1986-05-27 Pfizer Inc. Intermediates for 6-(aminoacyloxymethyl) penicillanic acid 1,1-dioxides
US4675186A (en) * 1985-04-18 1987-06-23 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
US4762921A (en) * 1985-04-18 1988-08-09 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
JPS63144296U (fr) * 1987-03-12 1988-09-22
CN108107120B (zh) * 2017-12-12 2020-12-01 山东鑫泉医药有限公司 采用高效液相法测定中间产物6,6-二溴青霉烷酸的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207323A (en) * 1975-11-21 1980-06-10 Merck & Co., Inc. 6-Substituted methyl penicillins, derivatives and analogues thereof
IE49881B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide

Also Published As

Publication number Publication date
KR860000425B1 (ko) 1986-04-19
IL65306A (en) 1986-02-28
DE3261898D1 (en) 1985-02-28
ZA821901B (en) 1983-01-26
YU61882A (en) 1985-03-20
AU8176182A (en) 1982-11-04
IE820656L (en) 1982-09-23
DD203723A5 (de) 1983-11-02
PL130110B1 (en) 1984-07-31
EP0061313B1 (fr) 1985-01-16
CA1201709A (fr) 1986-03-11
HU186487B (en) 1985-08-28
IE52812B1 (en) 1988-03-16
AU527895B2 (en) 1983-03-31
JPS6325593B2 (fr) 1988-05-26
PT74624A (en) 1982-04-01
KR830009110A (ko) 1983-12-17
NO820897L (no) 1982-09-24
FI820992L (fi) 1982-09-24
JPS57169492A (en) 1982-10-19
CS228921B2 (en) 1984-05-14
ES510656A0 (es) 1983-04-16
SU1122230A3 (ru) 1984-10-30
PH18040A (en) 1985-03-08
GT198274394A (es) 1983-09-08
EP0061313A2 (fr) 1982-09-29
ATE11291T1 (de) 1985-02-15
ES8305769A1 (es) 1983-04-16
FI74285C (fi) 1988-01-11
IL65306A0 (en) 1982-05-31
EP0061313A3 (en) 1982-12-08
FI74285B (fi) 1987-09-30
NZ200068A (en) 1985-08-16
PT74624B (en) 1984-11-26
US4342768A (en) 1982-08-03
PL235576A1 (en) 1983-03-14
GR76107B (fr) 1984-08-03

Similar Documents

Publication Publication Date Title
DK160099C (da) Analogifremgangsmaade til fremstilling af optisk aktive eller racemiske 6-substituerede 2-penem-3-carboxylsyreforbindelser eller farmaceutisk anvendelige salte deraf
DK469589A (da) 7-substituerede derivater af 3,5-dihydroxyhept-6-ynsyre, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter
DK126982A (da) Fremgangsmaade til fremstilling af bis-estere af 1,1-alkandioler med 6beta-hydroxymethyl-penicillansyre-1,1-dioxid og en 6beta-acylaminopenicillansyre eller farmaceutisk acceptable salte deraf
DK148795C (da) Anologifremgangsmaade til fremstilling af 3-(2-morpholino-ethyl-amino)-5-phenyl-pyridazin eller farmaceutisk acceptable syreadditionssalte deraf
PT75778A (de) Kristalline salze von cefodizim und verfahren zu ihrer herstellung
DK297382A (da) Fremgangsmaade til fremstilling af 3-(3-(heteroarylalkyl)-1-indolyl)acryl-syre-derivater eller farmaceutisk acceptable salte deraf
DK224281A (da) Fremgangsmaade til fremstilling af 2,2-dimethylpenam-3-carboxylsyre-1,1-dioxid-forbindelser eller salte deraf
DK149841C (da) Analogifremgangsmaade til fremstilling af alfa-fluor-methyl-alfa-aminoalkansyrer eller farmaceutisk acceptable syreadditionssalte deraf
DE3382618D1 (de) Verfahren zur herstellung von(d)2-(6-methoxy-2-naphthyl)propionsaeure und pharmazeutisch verwendbaren salzen davon und neue zwischenprodukte.
PT72421A (de) Verfahren zur herstellung von kristallinen salzen
DK72282A (da) Fremgangsmaade til fremstilling af bis-estere af 1,1-alkandioler med 2beta-acetoxymethyl-2alfa-methyl-(5r)penam-3alfa-carboxylsyre-1,1-dioxid og en 6-acylaminopenicillansyre eller farmaceutisk acceptable salte deraf
SE8701192L (sv) Nya 2-aminotiazolderivat eller salter derav for framstellning av 2-(2-aminotiazol-4-yl)-glyoxylsyraderivat eller ett salt derav samt forfarande for framstellning av dessa
IT8025223A0 (it) Procedimento per la produzione di derivati dell'acido penicillanico.
DK148036C (da) Analogifremgangsmaade til fremstilling af epimere 4''-amino-erythromycin-forbindelser eller syreadditionssalte deraf
DK155604C (da) Fremgangsmaade til fremstilling af 6-aminopenicillansyre-1,1-dioxid og dets ikke-toxiske, farmaceutisk acceptable salte
IT7921809A0 (it) Metodo per la produzione di derivati dell'acido 6-beta-amidino-penicillanico.
DK150856C (da) Analogifremgangsmaade til fremstilling af 6-(alfa-(imidoylaminoalkanoylamino)phenylacetamido)penicillansyreforbindelser eller farmaceutisk acceptable salte deraf
DK156652C (da) Analogifremgangsmaade til fremstilling af pyridinyloxypropanolamin-derivater eller farmaceutiske acceptable syreadditionssalte deraf
DE68922207D1 (de) Verfahren zur Herstellung von Alkalimetall-Salze von 3,7-substituierten 7-Aminocephalosporansauerderivaten.
DK13885D0 (da) Analogifremgangsmaade til fremstilling af 3-(2-(3-oxo-4-morpholinyl)-ethylamino)-4-methyl-6-phenyl-pyridazinderivater eller farmaceutisk acceptable syreadditionssalte
IT7919896A0 (it) Procedimento per la preparazione di sali, diversi dal cloridrato, dell'estere ftalidilico dell'acido 6-[d(-)-alfa-aminofenilacetamido]penicillanico.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment