PH18040A - Bis-esters of 1,1-alkanediols with 6-beta-hydroxy-methylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics - Google Patents

Bis-esters of 1,1-alkanediols with 6-beta-hydroxy-methylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Info

Publication number
PH18040A
PH18040A PH27042A PH27042A PH18040A PH 18040 A PH18040 A PH 18040A PH 27042 A PH27042 A PH 27042A PH 27042 A PH27042 A PH 27042A PH 18040 A PH18040 A PH 18040A
Authority
PH
Philippines
Prior art keywords
beta
esters
dioxide
alkanediols
bis
Prior art date
Application number
PH27042A
Other languages
English (en)
Inventor
Michael Stephen Hellogg
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH18040A publication Critical patent/PH18040A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PH27042A 1981-03-23 1982-03-23 Bis-esters of 1,1-alkanediols with 6-beta-hydroxy-methylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics PH18040A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/246,505 US4342768A (en) 1979-10-22 1981-03-23 Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Publications (1)

Publication Number Publication Date
PH18040A true PH18040A (en) 1985-03-08

Family

ID=22930958

Family Applications (1)

Application Number Title Priority Date Filing Date
PH27042A PH18040A (en) 1981-03-23 1982-03-23 Bis-esters of 1,1-alkanediols with 6-beta-hydroxy-methylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Country Status (26)

Country Link
US (1) US4342768A (fr)
EP (1) EP0061313B1 (fr)
JP (1) JPS57169492A (fr)
KR (1) KR860000425B1 (fr)
AT (1) ATE11291T1 (fr)
AU (1) AU527895B2 (fr)
CA (1) CA1201709A (fr)
CS (1) CS228921B2 (fr)
DD (1) DD203723A5 (fr)
DE (1) DE3261898D1 (fr)
DK (1) DK126982A (fr)
ES (1) ES510656A0 (fr)
FI (1) FI74285C (fr)
GR (1) GR76107B (fr)
GT (1) GT198274394A (fr)
HU (1) HU186487B (fr)
IE (1) IE52812B1 (fr)
IL (1) IL65306A (fr)
NO (1) NO820897L (fr)
NZ (1) NZ200068A (fr)
PH (1) PH18040A (fr)
PL (1) PL130110B1 (fr)
PT (1) PT74624B (fr)
SU (1) SU1122230A3 (fr)
YU (1) YU61882A (fr)
ZA (1) ZA821901B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3274453D1 (en) * 1981-09-22 1987-01-15 Kureha Chemical Ind Co Ltd Penicillin derivatives
US4452796A (en) * 1982-06-14 1984-06-05 Pfizer Inc. 6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
EP0084730A1 (fr) * 1982-01-22 1983-08-03 Beecham Group Plc Esters de dérivés de pénicilline avec des inhibiteurs de bêta-lactamase, leur préparation et leur application
FR2520362B1 (fr) * 1982-01-26 1986-04-11 Leo Pharm Prod Ltd Nouveaux composes de type b-lactame, y compris leurs sels formes avec des acides ou des bases acceptables en pharmacie, procedes pour produire ces composes, medicaments les contenant et leur utilisation pour combattre les maladies infectieuses
US4462934A (en) * 1983-03-31 1984-07-31 Pfizer Inc. Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides
US4536393A (en) * 1983-06-06 1985-08-20 Pfizer Inc. 6-(Aminomethyl)penicillanic acid 1,1-dioxide esters and intermediates therefor
US4503040A (en) * 1984-02-27 1985-03-05 Pfizer Inc. 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4591459A (en) * 1984-12-03 1986-05-27 Pfizer Inc. Intermediates for 6-(aminoacyloxymethyl) penicillanic acid 1,1-dioxides
US4675186A (en) 1985-04-18 1987-06-23 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
US4762921A (en) * 1985-04-18 1988-08-09 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
JPS63144296U (fr) * 1987-03-12 1988-09-22
CN108107120B (zh) * 2017-12-12 2020-12-01 山东鑫泉医药有限公司 采用高效液相法测定中间产物6,6-二溴青霉烷酸的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207323A (en) * 1975-11-21 1980-06-10 Merck & Co., Inc. 6-Substituted methyl penicillins, derivatives and analogues thereof
IE49880B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide

Also Published As

Publication number Publication date
FI74285C (fi) 1988-01-11
SU1122230A3 (ru) 1984-10-30
EP0061313A2 (fr) 1982-09-29
CA1201709A (fr) 1986-03-11
US4342768A (en) 1982-08-03
AU8176182A (en) 1982-11-04
ATE11291T1 (de) 1985-02-15
IL65306A (en) 1986-02-28
PT74624A (en) 1982-04-01
EP0061313B1 (fr) 1985-01-16
JPS6325593B2 (fr) 1988-05-26
PT74624B (en) 1984-11-26
ZA821901B (en) 1983-01-26
AU527895B2 (en) 1983-03-31
GR76107B (fr) 1984-08-03
NO820897L (no) 1982-09-24
DD203723A5 (de) 1983-11-02
PL130110B1 (en) 1984-07-31
ES8305769A1 (es) 1983-04-16
DE3261898D1 (en) 1985-02-28
NZ200068A (en) 1985-08-16
CS228921B2 (en) 1984-05-14
PL235576A1 (en) 1983-03-14
JPS57169492A (en) 1982-10-19
ES510656A0 (es) 1983-04-16
FI820992L (fi) 1982-09-24
FI74285B (fi) 1987-09-30
GT198274394A (es) 1983-09-08
DK126982A (da) 1982-09-24
HU186487B (en) 1985-08-28
EP0061313A3 (en) 1982-12-08
IE820656L (en) 1982-09-23
KR860000425B1 (ko) 1986-04-19
KR830009110A (ko) 1983-12-17
IL65306A0 (en) 1982-05-31
YU61882A (en) 1985-03-20
IE52812B1 (en) 1988-03-16

Similar Documents

Publication Publication Date Title
PH15706A (en) Esters of penicillanic acid 1,1-dioxide
IE781140L (en) Penicillanic acid s-oxides
DE3261898D1 (en) Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics
PL238200A1 (en) Process for preparing novel penicillins
EG14437A (en) Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof
ES2052511T3 (es) Acidos 4-halogeno-2-oxiimino-3-oxobutiricos.
IE820342L (en) Penicillins
JPS5690088A (en) Novel cephalosporin analog compound
ATE136306T1 (de) Solvate von einem beta-lactam-antibiotikum
ZA80646B (en) Process and intermediates for penicillanic acid,1,1-dioxide and esters thereof
IE810102L (en) Penicillin compounds
PT83311A (en) Process for the preparation of 6-amino penicillanic acid 1,1-dioxide by oxidation of this acid
HUT34203A (en) Process for producing 6-/amino-methyl/-penicillanic acid-1,1-dioxide and derivatives
ZA793092B (en) Combinations of penicillanic acid 1,1-dioxide with 7-(d-2-(4-ethyl-piperazin-2,3-dione-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-5-tetrazolyl)thiomethyl)-3-desacetoxymethylcephalosporanic acid
PH19472A (en) Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof