ES8305769A1 - Un procedimiento para la preparacion de bis-esteres de 1,1-alcanodioles. - Google Patents

Un procedimiento para la preparacion de bis-esteres de 1,1-alcanodioles.

Info

Publication number
ES8305769A1
ES8305769A1 ES510656A ES510656A ES8305769A1 ES 8305769 A1 ES8305769 A1 ES 8305769A1 ES 510656 A ES510656 A ES 510656A ES 510656 A ES510656 A ES 510656A ES 8305769 A1 ES8305769 A1 ES 8305769A1
Authority
ES
Spain
Prior art keywords
beta
esters
dioxide
alkanediols
hydroxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510656A
Other languages
English (en)
Other versions
ES510656A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES8305769A1 publication Critical patent/ES8305769A1/es
Publication of ES510656A0 publication Critical patent/ES510656A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE BIS-ESTERES DE 1,1-ALCANODIOLES Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES Y R ES HIDROGENO O METILO. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA WCOOCHR -X CON UNA SAL CARBOXILATO DE FORMULA W -COOM, EN LAS QUE X ES UN GRUPO SALIENTE; R ES HIDROGENO O METILO, M ES ANION FORMADOR DE UNA SAL DE CARBOXILATO; Y W Y W PUEDEN SER VARIOS TIPOS DE RADICALES; SEGUIDA DE HIDROGENACION DEL PRODUCTO FORMADO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIBACTERIANOS.
ES510656A 1981-03-23 1982-03-22 Un procedimiento para la preparacion de bis-esteres de 1,1-alcanodioles. Granted ES510656A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/246,505 US4342768A (en) 1979-10-22 1981-03-23 Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Publications (2)

Publication Number Publication Date
ES8305769A1 true ES8305769A1 (es) 1983-04-16
ES510656A0 ES510656A0 (es) 1983-04-16

Family

ID=22930958

Family Applications (1)

Application Number Title Priority Date Filing Date
ES510656A Granted ES510656A0 (es) 1981-03-23 1982-03-22 Un procedimiento para la preparacion de bis-esteres de 1,1-alcanodioles.

Country Status (26)

Country Link
US (1) US4342768A (es)
EP (1) EP0061313B1 (es)
JP (1) JPS57169492A (es)
KR (1) KR860000425B1 (es)
AT (1) ATE11291T1 (es)
AU (1) AU527895B2 (es)
CA (1) CA1201709A (es)
CS (1) CS228921B2 (es)
DD (1) DD203723A5 (es)
DE (1) DE3261898D1 (es)
DK (1) DK126982A (es)
ES (1) ES510656A0 (es)
FI (1) FI74285C (es)
GR (1) GR76107B (es)
GT (1) GT198274394A (es)
HU (1) HU186487B (es)
IE (1) IE52812B1 (es)
IL (1) IL65306A (es)
NO (1) NO820897L (es)
NZ (1) NZ200068A (es)
PH (1) PH18040A (es)
PL (1) PL130110B1 (es)
PT (1) PT74624B (es)
SU (1) SU1122230A3 (es)
YU (1) YU61882A (es)
ZA (1) ZA821901B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540689A (en) * 1981-09-22 1985-09-10 Kureha Kagaku Kogyo Kabushiki Kaisha Penicillin derivative
US4452796A (en) * 1982-06-14 1984-06-05 Pfizer Inc. 6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
EP0084730A1 (en) * 1982-01-22 1983-08-03 Beecham Group Plc Esters of penicillin derivatives with beta-lactamase inhibitors, their preparation and their use
FR2520362B1 (fr) * 1982-01-26 1986-04-11 Leo Pharm Prod Ltd Nouveaux composes de type b-lactame, y compris leurs sels formes avec des acides ou des bases acceptables en pharmacie, procedes pour produire ces composes, medicaments les contenant et leur utilisation pour combattre les maladies infectieuses
US4462934A (en) * 1983-03-31 1984-07-31 Pfizer Inc. Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides
US4536393A (en) * 1983-06-06 1985-08-20 Pfizer Inc. 6-(Aminomethyl)penicillanic acid 1,1-dioxide esters and intermediates therefor
US4503040A (en) * 1984-02-27 1985-03-05 Pfizer Inc. 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4591459A (en) * 1984-12-03 1986-05-27 Pfizer Inc. Intermediates for 6-(aminoacyloxymethyl) penicillanic acid 1,1-dioxides
US4675186A (en) * 1985-04-18 1987-06-23 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
US4762921A (en) * 1985-04-18 1988-08-09 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
JPS63144296U (es) * 1987-03-12 1988-09-22
CN108107120B (zh) * 2017-12-12 2020-12-01 山东鑫泉医药有限公司 采用高效液相法测定中间产物6,6-二溴青霉烷酸的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207323A (en) * 1975-11-21 1980-06-10 Merck & Co., Inc. 6-Substituted methyl penicillins, derivatives and analogues thereof
IE49881B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide

Also Published As

Publication number Publication date
NZ200068A (en) 1985-08-16
PL130110B1 (en) 1984-07-31
IL65306A0 (en) 1982-05-31
GR76107B (es) 1984-08-03
ZA821901B (en) 1983-01-26
JPS6325593B2 (es) 1988-05-26
EP0061313B1 (en) 1985-01-16
JPS57169492A (en) 1982-10-19
GT198274394A (es) 1983-09-08
NO820897L (no) 1982-09-24
KR860000425B1 (ko) 1986-04-19
CS228921B2 (en) 1984-05-14
DK126982A (da) 1982-09-24
PL235576A1 (en) 1983-03-14
DD203723A5 (de) 1983-11-02
YU61882A (en) 1985-03-20
EP0061313A2 (en) 1982-09-29
FI74285B (fi) 1987-09-30
AU8176182A (en) 1982-11-04
ATE11291T1 (de) 1985-02-15
KR830009110A (ko) 1983-12-17
ES510656A0 (es) 1983-04-16
CA1201709A (en) 1986-03-11
DE3261898D1 (en) 1985-02-28
IL65306A (en) 1986-02-28
FI74285C (fi) 1988-01-11
PT74624B (en) 1984-11-26
US4342768A (en) 1982-08-03
IE52812B1 (en) 1988-03-16
IE820656L (en) 1982-09-23
SU1122230A3 (ru) 1984-10-30
EP0061313A3 (en) 1982-12-08
PT74624A (en) 1982-04-01
HU186487B (en) 1985-08-28
FI820992L (fi) 1982-09-24
AU527895B2 (en) 1983-03-31
PH18040A (en) 1985-03-08

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