JPS57169492A - Bis-esters of 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and 1,1-alkanediol and beta-lactam antibiotics - Google Patents

Bis-esters of 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and 1,1-alkanediol and beta-lactam antibiotics

Info

Publication number
JPS57169492A
JPS57169492A JP57046183A JP4618382A JPS57169492A JP S57169492 A JPS57169492 A JP S57169492A JP 57046183 A JP57046183 A JP 57046183A JP 4618382 A JP4618382 A JP 4618382A JP S57169492 A JPS57169492 A JP S57169492A
Authority
JP
Japan
Prior art keywords
beta
esters
dioxide
hydroxymethyl
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57046183A
Other languages
English (en)
Other versions
JPS6325593B2 (ja
Inventor
Suteiibun Kerotsugu Maikeru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPS57169492A publication Critical patent/JPS57169492A/ja
Publication of JPS6325593B2 publication Critical patent/JPS6325593B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP57046183A 1981-03-23 1982-03-23 Bis-esters of 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and 1,1-alkanediol and beta-lactam antibiotics Granted JPS57169492A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/246,505 US4342768A (en) 1979-10-22 1981-03-23 Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Publications (2)

Publication Number Publication Date
JPS57169492A true JPS57169492A (en) 1982-10-19
JPS6325593B2 JPS6325593B2 (ja) 1988-05-26

Family

ID=22930958

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57046183A Granted JPS57169492A (en) 1981-03-23 1982-03-23 Bis-esters of 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and 1,1-alkanediol and beta-lactam antibiotics

Country Status (26)

Country Link
US (1) US4342768A (ja)
EP (1) EP0061313B1 (ja)
JP (1) JPS57169492A (ja)
KR (1) KR860000425B1 (ja)
AT (1) ATE11291T1 (ja)
AU (1) AU527895B2 (ja)
CA (1) CA1201709A (ja)
CS (1) CS228921B2 (ja)
DD (1) DD203723A5 (ja)
DE (1) DE3261898D1 (ja)
DK (1) DK126982A (ja)
ES (1) ES8305769A1 (ja)
FI (1) FI74285C (ja)
GR (1) GR76107B (ja)
GT (1) GT198274394A (ja)
HU (1) HU186487B (ja)
IE (1) IE52812B1 (ja)
IL (1) IL65306A (ja)
NO (1) NO820897L (ja)
NZ (1) NZ200068A (ja)
PH (1) PH18040A (ja)
PL (1) PL130110B1 (ja)
PT (1) PT74624B (ja)
SU (1) SU1122230A3 (ja)
YU (1) YU61882A (ja)
ZA (1) ZA821901B (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540689A (en) * 1981-09-22 1985-09-10 Kureha Kagaku Kogyo Kabushiki Kaisha Penicillin derivative
US4452796A (en) * 1982-06-14 1984-06-05 Pfizer Inc. 6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
EP0084730A1 (en) * 1982-01-22 1983-08-03 Beecham Group Plc Esters of penicillin derivatives with beta-lactamase inhibitors, their preparation and their use
FR2520362B1 (fr) * 1982-01-26 1986-04-11 Leo Pharm Prod Ltd Nouveaux composes de type b-lactame, y compris leurs sels formes avec des acides ou des bases acceptables en pharmacie, procedes pour produire ces composes, medicaments les contenant et leur utilisation pour combattre les maladies infectieuses
US4462934A (en) * 1983-03-31 1984-07-31 Pfizer Inc. Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides
US4536393A (en) * 1983-06-06 1985-08-20 Pfizer Inc. 6-(Aminomethyl)penicillanic acid 1,1-dioxide esters and intermediates therefor
US4503040A (en) * 1984-02-27 1985-03-05 Pfizer Inc. 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4591459A (en) * 1984-12-03 1986-05-27 Pfizer Inc. Intermediates for 6-(aminoacyloxymethyl) penicillanic acid 1,1-dioxides
US4675186A (en) 1985-04-18 1987-06-23 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
US4762921A (en) * 1985-04-18 1988-08-09 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
JPS63144296U (ja) * 1987-03-12 1988-09-22
CN108107120B (zh) * 2017-12-12 2020-12-01 山东鑫泉医药有限公司 采用高效液相法测定中间产物6,6-二溴青霉烷酸的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207323A (en) * 1975-11-21 1980-06-10 Merck & Co., Inc. 6-Substituted methyl penicillins, derivatives and analogues thereof
IE49881B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide

Also Published As

Publication number Publication date
HU186487B (en) 1985-08-28
FI74285B (fi) 1987-09-30
PH18040A (en) 1985-03-08
GR76107B (ja) 1984-08-03
PL235576A1 (en) 1983-03-14
DE3261898D1 (en) 1985-02-28
ATE11291T1 (de) 1985-02-15
DD203723A5 (de) 1983-11-02
IL65306A0 (en) 1982-05-31
ES510656A0 (es) 1983-04-16
DK126982A (da) 1982-09-24
PT74624A (en) 1982-04-01
EP0061313A2 (en) 1982-09-29
AU527895B2 (en) 1983-03-31
GT198274394A (es) 1983-09-08
PL130110B1 (en) 1984-07-31
AU8176182A (en) 1982-11-04
IE820656L (en) 1982-09-23
NZ200068A (en) 1985-08-16
FI74285C (fi) 1988-01-11
IL65306A (en) 1986-02-28
FI820992L (fi) 1982-09-24
SU1122230A3 (ru) 1984-10-30
EP0061313A3 (en) 1982-12-08
PT74624B (en) 1984-11-26
US4342768A (en) 1982-08-03
CA1201709A (en) 1986-03-11
CS228921B2 (en) 1984-05-14
IE52812B1 (en) 1988-03-16
KR860000425B1 (ko) 1986-04-19
JPS6325593B2 (ja) 1988-05-26
YU61882A (en) 1985-03-20
KR830009110A (ko) 1983-12-17
NO820897L (no) 1982-09-24
ES8305769A1 (es) 1983-04-16
ZA821901B (en) 1983-01-26
EP0061313B1 (en) 1985-01-16

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