DK1245564T3 - Benzamidinderivater - Google Patents

Benzamidinderivater

Info

Publication number
DK1245564T3
DK1245564T3 DK00970070T DK00970070T DK1245564T3 DK 1245564 T3 DK1245564 T3 DK 1245564T3 DK 00970070 T DK00970070 T DK 00970070T DK 00970070 T DK00970070 T DK 00970070T DK 1245564 T3 DK1245564 T3 DK 1245564T3
Authority
DK
Denmark
Prior art keywords
group
optionally substituted
hydrogen atom
alkyl group
halogen atom
Prior art date
Application number
DK00970070T
Other languages
Danish (da)
English (en)
Inventor
Koichi Fujimoto
Fumitoshi Asai
Hayao Matsuhashi
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of DK1245564T3 publication Critical patent/DK1245564T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Manufacture Of Alloys Or Alloy Compounds (AREA)
DK00970070T 1999-10-28 2000-10-25 Benzamidinderivater DK1245564T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30719299 1999-10-28

Publications (1)

Publication Number Publication Date
DK1245564T3 true DK1245564T3 (da) 2006-08-14

Family

ID=17966162

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00970070T DK1245564T3 (da) 1999-10-28 2000-10-25 Benzamidinderivater

Country Status (26)

Country Link
US (3) US6555556B1 (pt)
EP (1) EP1245564B1 (pt)
KR (1) KR100642953B1 (pt)
CN (2) CN1293052C (pt)
AT (1) ATE322479T1 (pt)
AU (1) AU776193B2 (pt)
BR (1) BR0015120A (pt)
CA (1) CA2389156C (pt)
CY (1) CY1106116T1 (pt)
CZ (1) CZ20021432A3 (pt)
DE (1) DE60027204T2 (pt)
DK (1) DK1245564T3 (pt)
ES (1) ES2261248T3 (pt)
HK (1) HK1047431B (pt)
HU (1) HUP0203161A3 (pt)
IL (2) IL149306A0 (pt)
MX (1) MXPA02004218A (pt)
NO (1) NO323147B1 (pt)
NZ (1) NZ518581A (pt)
PL (1) PL354619A1 (pt)
PT (1) PT1245564E (pt)
RU (1) RU2222529C2 (pt)
TR (1) TR200201654T2 (pt)
TW (1) TWI226886B (pt)
WO (1) WO2001030756A1 (pt)
ZA (1) ZA200203278B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1245564T3 (da) * 1999-10-28 2006-08-14 Sankyo Co Benzamidinderivater
CZ20032728A3 (cs) * 2001-04-05 2004-02-18 Sankyo Company, Limited Benzamidinové deriváty
WO2002089803A1 (en) * 2001-05-07 2002-11-14 Sankyo Company, Limited Composition for iontophoresis
MXPA04009007A (es) * 2002-03-15 2005-07-01 Kissei Pharmaceutical Nuevos cristales de derivado de 5-hidroxicarbamimidoil-2-hidroxi-bencenosulfonamida.
US20070254930A1 (en) * 2004-11-23 2007-11-01 Dong Wha Pharm. Ind. Co., Ltd. Oral Preparation Having Improved Bioavailability
CN103159620A (zh) * 2013-03-28 2013-06-19 广西师范大学 一种2-羟基间苯二甲酸的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA928276B (en) 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.
US5731324A (en) * 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
ZA951617B (en) * 1994-03-04 1997-02-27 Lilly Co Eli Antithrombotic agents.
ES2193202T3 (es) 1994-12-02 2003-11-01 Yamanouchi Pharma Co Ltd Nuevo derivado de amidinonaftilo o sal de este.
BR9612423B1 (pt) * 1996-01-02 2010-11-30 composto de n-[(amino-imino-metil ou amino-metil) fenil] propil amidas substituìdas, e, composição farmacêutica.
JP3565864B2 (ja) * 1996-09-12 2004-09-15 シエーリング アクチエンゲゼルシヤフト 環式アミノ酸または環式ヒドロキシ酸誘導体により置換されたベンズアミジン誘導体および抗擬固薬としてのこれらの使用
TW542822B (en) * 1997-01-17 2003-07-21 Ajinomoto Kk Benzamidine derivatives
US6399627B1 (en) * 1999-02-11 2002-06-04 Cor Therapeutics, Inc. Inhibitors of factor Xa
US6350761B1 (en) * 1999-07-30 2002-02-26 Berlex Laboratories, Inc. Benzenamine derivatives as anti-coagulants
DK1245564T3 (da) * 1999-10-28 2006-08-14 Sankyo Co Benzamidinderivater

Also Published As

Publication number Publication date
ES2261248T3 (es) 2006-11-16
NO323147B1 (no) 2007-01-08
US20040248981A1 (en) 2004-12-09
NO20021990D0 (no) 2002-04-26
US20040010009A1 (en) 2004-01-15
KR100642953B1 (ko) 2006-11-10
CA2389156A1 (en) 2001-05-03
KR20020092347A (ko) 2002-12-11
AU7957400A (en) 2001-05-08
CN1413189A (zh) 2003-04-23
RU2222529C2 (ru) 2004-01-27
ATE322479T1 (de) 2006-04-15
IL149306A0 (en) 2002-11-10
CN1572882A (zh) 2005-02-02
HK1047431B (zh) 2006-07-14
CN1293052C (zh) 2007-01-03
BR0015120A (pt) 2002-06-25
HUP0203161A3 (en) 2003-12-29
CY1106116T1 (el) 2011-06-08
NO20021990L (no) 2002-06-25
DE60027204T2 (de) 2006-11-23
AU776193B2 (en) 2004-09-02
DE60027204D1 (en) 2006-05-18
EP1245564A4 (en) 2003-03-05
IL149306A (en) 2007-07-04
TWI226886B (en) 2005-01-21
TR200201654T2 (tr) 2002-12-23
CA2389156C (en) 2009-05-12
WO2001030756A1 (fr) 2001-05-03
ZA200203278B (en) 2003-08-26
MXPA02004218A (es) 2002-10-17
EP1245564A1 (en) 2002-10-02
PT1245564E (pt) 2006-06-30
US6555556B1 (en) 2003-04-29
HUP0203161A2 (hu) 2002-12-28
HK1047431A1 (en) 2003-02-21
PL354619A1 (en) 2004-02-09
NZ518581A (en) 2004-11-26
CZ20021432A3 (cs) 2002-10-16
EP1245564B1 (en) 2006-04-05

Similar Documents

Publication Publication Date Title
WO2002081448A1 (fr) Derive benzamidine
GB9801690D0 (en) Therapeutic agents
MA28010A1 (fr) Derives de piperazine et leur utilisation comme agents therapeutiques
EP1070714A4 (en) Amidine CONNECTIONS
WO2000071510A3 (en) INHIBITORS OF FACTOR Xa
PT863875E (pt) Novos compostos 4-(oxialcoxifenil)-3-oxi-piperidina para o tratamento de insuficiencia cardiaca e renal
DE69528005D1 (de) Prolineamid-Derivate
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
WO2000047554A3 (en) INHIBITORS OF FACTOR Xa
NO20052182L (no) Nye forbindelser
DK0976748T3 (da) Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet
NO20060147L (no) Benzimidazolderivater, sammensetninger som inneholder slike, fremstilling derav og anvendelse derav
DK0976722T3 (da) Benzamidin-derivater
DE60230127D1 (de) Inhibitoren von integrin alpha-v-beta-6
TW200420545A (en) 1-(4-benzyl-piperazin-1-yl)-3-phenyl-propenone derivatives
TR200001452T2 (tr) Bifenilamidin türevleri.
NO20022123L (no) Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
ATE322479T1 (de) Benzamidinderivate
DK0896822T3 (da) 4-aminopyrrol (3,2-d) pyrimidiner som neuropeptide Y receptorantagonister
ATE293961T1 (de) Verwendung von hydantoin und seinen derivaten gegen hypalbuminämie
HRP20010885B1 (en) Ethanesulfonyl-piperidine derivatives
TR200200017T2 (tr) Benzofuran türevleri
AU1651201A (en) Amidinophenylpyruvic acid derivative
NO893039L (no) Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler.
NO20004075L (no) Substituerte pyrimidin-2-yloksy-karboksylsyrederivater, fremstilling av disse og deres anvendelse som endotelin- antagonister