DK1188747T3 - Phenoxypropylaminforbindelser - Google Patents
PhenoxypropylaminforbindelserInfo
- Publication number
- DK1188747T3 DK1188747T3 DK00927844T DK00927844T DK1188747T3 DK 1188747 T3 DK1188747 T3 DK 1188747T3 DK 00927844 T DK00927844 T DK 00927844T DK 00927844 T DK00927844 T DK 00927844T DK 1188747 T3 DK1188747 T3 DK 1188747T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenoxypropylamine
- compound
- antidepressants
- hydrates
- expressing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14275099 | 1999-05-24 | ||
JP16616099 | 1999-06-14 | ||
JP27738499 | 1999-09-29 | ||
JP2000018080 | 2000-01-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1188747T3 true DK1188747T3 (da) | 2006-01-23 |
Family
ID=27472476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00927844T DK1188747T3 (da) | 1999-05-24 | 2000-05-22 | Phenoxypropylaminforbindelser |
Country Status (17)
Country | Link |
---|---|
US (2) | US6720320B2 (fr) |
EP (1) | EP1188747B1 (fr) |
JP (1) | JP3893878B2 (fr) |
KR (2) | KR100799134B1 (fr) |
CN (1) | CN1164574C (fr) |
AT (1) | ATE303987T1 (fr) |
AU (1) | AU777594B2 (fr) |
BR (1) | BR0011542A (fr) |
CA (2) | CA2716369C (fr) |
DE (1) | DE60022504T2 (fr) |
DK (1) | DK1188747T3 (fr) |
EA (1) | EA004704B1 (fr) |
ES (1) | ES2244438T3 (fr) |
IL (2) | IL146564A0 (fr) |
MX (1) | MXPA01012046A (fr) |
NZ (1) | NZ516111A (fr) |
WO (1) | WO2000071517A1 (fr) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001046177A1 (fr) * | 1999-12-20 | 2001-06-28 | Eli Lilly And Company | Derives de benzofuranne |
US7144898B2 (en) | 1999-12-20 | 2006-12-05 | Eli Lilly And Company | Indole derivatives for the treatment of depression and anxiety |
WO2002042297A1 (fr) * | 2000-11-27 | 2002-05-30 | Mitsubishi Pharma Corporation | Composes de piperidine et son utilisation medicale |
WO2004029048A1 (fr) * | 2002-09-26 | 2004-04-08 | Warner-Lambert Company Llc | Piperazines substituees heterocycliques destinees au traitement de la schizophrenie |
SE0303280D0 (sv) * | 2003-12-05 | 2003-12-05 | Astrazeneca Ab | Novel compounds |
JP2007513197A (ja) * | 2003-12-08 | 2007-05-24 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 統合失調症の治療のための複素環式置換インダン誘導体および関連化合物 |
GB0407025D0 (en) * | 2004-03-29 | 2004-04-28 | Glaxo Group Ltd | Novel compounds |
US7674822B2 (en) | 2004-11-24 | 2010-03-09 | Wyeth | PTP1b inhibitors |
WO2006101454A1 (fr) * | 2005-03-21 | 2006-09-28 | S*Bio Pte Ltd | Derives du benzothiophene: preparation et applications pharmaceutiques |
TWI320783B (en) | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
EP2559690B1 (fr) | 2005-05-10 | 2016-03-30 | Incyte Holdings Corporation | Modulateurs de l'indolamine 2,3-dioxygenase et leurs procedes d'utilisation |
AR055203A1 (es) | 2005-08-31 | 2007-08-08 | Otsuka Pharma Co Ltd | Derivados de benzotiofeno con propiedades antipsicoticas |
WO2007065655A1 (fr) * | 2005-12-07 | 2007-06-14 | Neurosearch Sweden Ab | Phenylpiperidines disubstituees utiles en tant que modulateurs de la neurotransmission catecholaminergique corticale |
WO2007075598A2 (fr) | 2005-12-20 | 2007-07-05 | Incyte Corporation | N-hydroxyamidinoheterocycles en tant que modulateurs d'indoleamine 2,3-dioxygenase |
US7910592B2 (en) | 2005-12-30 | 2011-03-22 | Merck Sharp & Dohme Corp. | CETP inhibitors |
US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
US7649098B2 (en) * | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
CL2007002650A1 (es) * | 2006-09-19 | 2008-02-08 | Incyte Corp | Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras. |
EP2064207B1 (fr) | 2006-09-19 | 2013-11-06 | Incyte Corporation | N-hydroxyamidinohétérocycles en tant que modulateurs d'indoléamine 2,3-dioxygénase |
JP2008195654A (ja) * | 2007-02-14 | 2008-08-28 | Mitsubishi Tanabe Pharma Corp | ベンゾ[b]フラン化合物の新規結晶形 |
US20090270496A1 (en) * | 2007-05-03 | 2009-10-29 | Courchesne William E | Antifungal compounds |
TW200920355A (en) * | 2007-09-06 | 2009-05-16 | Lexicon Pharmaceuticals Inc | Compositions and methods for treating immunological and inflammatory diseases and disorders |
IE20070928A1 (en) * | 2007-12-21 | 2009-09-30 | Giuliani Int Ltd | Multi target ligands |
KR101927291B1 (ko) | 2008-07-08 | 2018-12-10 | 인사이트 홀딩스 코포레이션 | 인돌아민 2,3-디옥시게나아제의 억제제로서의 1,2,5-옥사디아졸 |
EP2398775B1 (fr) | 2009-02-18 | 2019-04-24 | Cornell University | Système de reconnaissance/détection couplée pour une utilisation in vivo et in vitro |
US8324250B2 (en) | 2009-03-19 | 2012-12-04 | Hoffmann-La Roche Inc. | Piperidine derivatives as NK3 receptor antagonists |
WO2011022679A2 (fr) * | 2009-08-20 | 2011-02-24 | University Of Tennessee Research Foundation, The | Composés cannabinoïdes benzofurane et méthodes dutilisation associées |
WO2013016694A2 (fr) | 2011-07-27 | 2013-01-31 | Cornell University | Procédé pour la détection et la quantification d'arn |
NZ750189A (en) * | 2013-01-24 | 2020-08-28 | Minerva Neurosciences Inc | Use of phenoxypropylamine compounds to treat depression |
PL3030561T3 (pl) | 2013-08-07 | 2017-08-31 | Cadila Healthcare Limited | N-cyjanometyloamidy jako inhibitory kinaz janusowych |
US9664676B2 (en) | 2013-09-06 | 2017-05-30 | Cornell University | RNA sequences that induce fluorescence of small molecule fluorophores |
US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
DK3066085T3 (da) | 2013-11-08 | 2020-06-02 | Incyte Holdings Corp | Fremgangsmåde til syntesen af en indolamin-2,3-dioxygenaseinhibitor |
CN111943890B (zh) * | 2014-11-03 | 2023-10-31 | 艾欧米制药有限公司 | 药用化合物 |
CN106243088B (zh) | 2015-06-03 | 2019-01-04 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
ES2893616T3 (es) | 2015-06-19 | 2022-02-09 | Opko Biologics Ltd | Factores de coagulación de acción prolongada y métodos para la producción de los mismos |
CN114848641A (zh) * | 2016-05-25 | 2022-08-05 | 田边三菱制药株式会社 | 用于治疗焦虑症的化合物或其代谢物 |
AU2017296352A1 (en) | 2016-07-11 | 2019-02-21 | Opko Biologics Ltd. | Long-acting coagulation factor VII and methods of producing same |
KR20210061357A (ko) | 2018-09-04 | 2021-05-27 | 미네르바 뉴로사이언스즈, 인크. | 통증을 치료하기 위해 페녹시프로필아민 화합물을 사용하는 방법 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2042054A1 (de) * | 1970-08-25 | 1972-03-02 | Agfa Gevaert Ag | Photographisches Trockenkopierverfahren |
DE2106577C2 (de) * | 1971-02-11 | 1982-07-08 | Agfa-Gevaert Ag, 5090 Leverkusen | Aufzeichnungsmaterial für das photographische Trockenkopierverfahren und photographisches Verfahren zur Herstellung von Bildern |
JPS4718538U (fr) | 1971-03-31 | 1972-11-01 | ||
DE2337461A1 (de) * | 1973-07-24 | 1975-02-06 | Boehringer Mannheim Gmbh | Neue indolderivate und verfahren zu deren herstellung |
JPS5292610A (en) | 1976-01-26 | 1977-08-04 | Canon Kk | Electrostatic printing master |
JPS5290307A (en) | 1976-01-26 | 1977-07-29 | Canon Kk | Thermoodeveloping photoosensitive material for electrostatic printing master |
DE2702919A1 (de) * | 1976-01-26 | 1977-07-28 | Canon Kk | Durch erwaermung entwickelbares, lichtempfindliches aufzeichnungsmaterial |
US4191765A (en) * | 1976-05-25 | 1980-03-04 | Hoechst Aktiengesellschaft | 1-Aryloxy-2-hydroxy-3-aminopropanes |
DE2623314C2 (de) | 1976-05-25 | 1984-08-02 | Hoechst Ag, 6230 Frankfurt | 1-Aryloxy-2-Hydroxy-3-aminopropane, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
WO1980000152A1 (fr) * | 1978-07-03 | 1980-02-07 | Sandoz Ag | Derives d'un 3-aminopropoxy-aryle, leur preparation et utilisation |
JPS55100361A (en) | 1979-01-18 | 1980-07-31 | Sandoz Ag | 33aminopropoxyaryl derivative |
JPS58121214A (ja) * | 1982-01-09 | 1983-07-19 | Kanegafuchi Chem Ind Co Ltd | 血小板凝集阻害剤 |
JPS60202872A (ja) * | 1984-03-27 | 1985-10-14 | Kaken Pharmaceut Co Ltd | ベンゾフラン誘導体、その製法およびそれを有効成分とする降圧剤 |
DE3427985A1 (de) * | 1984-07-28 | 1986-01-30 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue 2h-l-benzopyran-2-on-derivate, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
JPS6157572A (ja) * | 1984-08-28 | 1986-03-24 | Kanegafuchi Chem Ind Co Ltd | 新規α−ベンジリデン−γ−ブチロラクトン誘導体 |
JPS61218582A (ja) * | 1985-03-23 | 1986-09-29 | Kaken Pharmaceut Co Ltd | ベンゾフラン誘導体、その製法およびそれを有効成分とする降圧剤 |
HU209759B (en) * | 1986-07-17 | 1994-10-28 | Hem Res Inc | Method for the preparation of synergistic pharmaceutical composition containing lymphokines and mismatched double-stranded rnas |
US4861897A (en) * | 1987-06-22 | 1989-08-29 | Ortho Pharmaceutical Corporation | 2-Aryloxyalkylaminobenzoxazoles and 2-aryloxyalkylaminobenzothiazoles |
HU209753B (en) | 1990-12-13 | 1995-02-28 | Richter Gedeon Vegyeszeti Gyar Rt. | Process for producing of 3-(4-nitrophenoxy)-propylamine derivatives and pharmaceutical compositions comprising them |
EP0579754A1 (fr) * | 1991-04-09 | 1994-01-26 | The Upjohn Company | Utilisation d'amines pour sensibiliser des cellules resistant a plusieurs medicaments |
US5281624A (en) | 1991-09-27 | 1994-01-25 | Eli Lilly And Company | N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof |
EP0691962B1 (fr) * | 1993-03-29 | 2000-09-13 | Basf Aktiengesellschaft | Derives de 1-amino-3-phenoxy-propane en tant que modulateurs de la resistance a des agents therapeutiques multiples |
US5500431A (en) * | 1993-04-14 | 1996-03-19 | Eli Lilly And Company | Tetrahydro-β-carbolines |
EP0620222A3 (fr) | 1993-04-14 | 1995-04-12 | Lilly Co Eli | Tétrahydro-bêta-carbolines. |
JPH0717952A (ja) * | 1993-06-29 | 1995-01-20 | Nissan Chem Ind Ltd | ベンジリデン誘導体 |
WO1995024200A1 (fr) * | 1994-03-11 | 1995-09-14 | Eli Lilly And Company | Methode de traitement d'etats associes au recepteur 5ht¿2b? |
US5789402A (en) * | 1995-01-17 | 1998-08-04 | Eli Lilly Company | Compounds having effects on serotonin-related systems |
US5576321A (en) * | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
JPH09136877A (ja) * | 1995-06-16 | 1997-05-27 | Takeda Chem Ind Ltd | 複素環化合物、その製造法及び用途 |
US5912256A (en) * | 1996-06-20 | 1999-06-15 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
ES2176877T3 (es) * | 1997-09-26 | 2002-12-01 | Kowa Co | Derivados de tetrazol como antagonistas de ltd4 y h1. |
JP4246822B2 (ja) | 1997-09-26 | 2009-04-02 | 興和株式会社 | テトラゾール誘導体 |
AU3667899A (en) * | 1998-04-29 | 1999-11-16 | American Home Products Corporation | Antipsychotic indolyl derivatives |
JP2000086603A (ja) * | 1998-07-15 | 2000-03-28 | Yoshitomi Pharmaceut Ind Ltd | 桂皮酸アミド誘導体および3―フェニルプロピオン酸アミド誘導体 |
EP1149094B1 (fr) * | 1998-12-18 | 2004-04-21 | Basilea Pharmaceutica AG | (aminoalcoxy)-4 benzofurannes comme inhibiteurs de la n-myristoyltransferase |
WO2002042297A1 (fr) * | 2000-11-27 | 2002-05-30 | Mitsubishi Pharma Corporation | Composes de piperidine et son utilisation medicale |
-
2000
- 2000-05-22 CA CA2716369A patent/CA2716369C/fr not_active Expired - Lifetime
- 2000-05-22 AT AT00927844T patent/ATE303987T1/de not_active IP Right Cessation
- 2000-05-22 IL IL14656400A patent/IL146564A0/xx not_active IP Right Cessation
- 2000-05-22 BR BR0011542-8A patent/BR0011542A/pt not_active IP Right Cessation
- 2000-05-22 EP EP00927844A patent/EP1188747B1/fr not_active Expired - Lifetime
- 2000-05-22 NZ NZ516111A patent/NZ516111A/en unknown
- 2000-05-22 CA CA2375008A patent/CA2375008C/fr not_active Expired - Lifetime
- 2000-05-22 ES ES00927844T patent/ES2244438T3/es not_active Expired - Lifetime
- 2000-05-22 CN CNB008086044A patent/CN1164574C/zh not_active Expired - Lifetime
- 2000-05-22 AU AU46160/00A patent/AU777594B2/en not_active Ceased
- 2000-05-22 DK DK00927844T patent/DK1188747T3/da active
- 2000-05-22 WO PCT/JP2000/003279 patent/WO2000071517A1/fr active IP Right Grant
- 2000-05-22 KR KR1020017015024A patent/KR100799134B1/ko active IP Right Grant
- 2000-05-22 EA EA200101232A patent/EA004704B1/ru not_active IP Right Cessation
- 2000-05-22 JP JP2000619774A patent/JP3893878B2/ja not_active Expired - Lifetime
- 2000-05-22 DE DE60022504T patent/DE60022504T2/de not_active Expired - Lifetime
- 2000-05-22 MX MXPA01012046A patent/MXPA01012046A/es active IP Right Grant
- 2000-05-22 KR KR1020077026625A patent/KR100882544B1/ko active IP Right Grant
-
2001
- 2001-11-19 IL IL146564A patent/IL146564A/en unknown
- 2001-11-23 US US09/990,389 patent/US6720320B2/en not_active Expired - Lifetime
-
2003
- 2003-12-22 US US10/740,418 patent/US7196199B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EA004704B1 (ru) | 2004-06-24 |
CA2375008A1 (fr) | 2000-11-30 |
AU4616000A (en) | 2000-12-12 |
DE60022504T2 (de) | 2006-06-29 |
US20040138227A1 (en) | 2004-07-15 |
CA2716369A1 (fr) | 2000-11-30 |
CN1378533A (zh) | 2002-11-06 |
IL146564A0 (en) | 2002-07-25 |
DE60022504D1 (de) | 2005-10-13 |
US20020111358A1 (en) | 2002-08-15 |
JP3893878B2 (ja) | 2007-03-14 |
BR0011542A (pt) | 2002-03-05 |
CA2375008C (fr) | 2011-01-04 |
EP1188747A4 (fr) | 2002-10-09 |
MXPA01012046A (es) | 2003-09-04 |
WO2000071517A1 (fr) | 2000-11-30 |
KR20070118193A (ko) | 2007-12-13 |
NZ516111A (en) | 2003-05-30 |
AU777594B2 (en) | 2004-10-21 |
ES2244438T3 (es) | 2005-12-16 |
KR100799134B1 (ko) | 2008-01-29 |
CA2716369C (fr) | 2013-05-14 |
US7196199B2 (en) | 2007-03-27 |
EA200101232A1 (ru) | 2002-06-27 |
KR100882544B1 (ko) | 2009-02-12 |
US6720320B2 (en) | 2004-04-13 |
CN1164574C (zh) | 2004-09-01 |
IL146564A (en) | 2006-12-31 |
EP1188747A1 (fr) | 2002-03-20 |
EP1188747B1 (fr) | 2005-09-07 |
ATE303987T1 (de) | 2005-09-15 |
KR20020012235A (ko) | 2002-02-15 |
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