DK1168934T3 - Hydrogeldannende system med hydrofobe og hydrofile komponenter - Google Patents
Hydrogeldannende system med hydrofobe og hydrofile komponenterInfo
- Publication number
- DK1168934T3 DK1168934T3 DK00917865T DK00917865T DK1168934T3 DK 1168934 T3 DK1168934 T3 DK 1168934T3 DK 00917865 T DK00917865 T DK 00917865T DK 00917865 T DK00917865 T DK 00917865T DK 1168934 T3 DK1168934 T3 DK 1168934T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydrophobic
- forming system
- hydrophilic components
- hydrogel forming
- unsaturated group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/02—Dextran; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
- C08G18/6484—Polysaccharides and derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/81—Unsaturated isocyanates or isothiocyanates
- C08G18/8108—Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/06—Unsaturated polyesters
- C08L67/07—Unsaturated polyesters having terminal carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2210/00—Compositions for preparing hydrogels
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
- Y10S525/937—Utility as body contact e.g. implant, contact lens or I.U.D.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Colloid Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Graft Or Block Polymers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12880399P | 1999-04-12 | 1999-04-12 | |
PCT/US2000/006416 WO2000060956A1 (fr) | 1999-04-12 | 2000-03-20 | Systeme de formation d'hydrogel a composants hydrophobes et hydrophiles |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1168934T3 true DK1168934T3 (da) | 2008-05-13 |
Family
ID=22437052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00917865T DK1168934T3 (da) | 1999-04-12 | 2000-03-20 | Hydrogeldannende system med hydrofobe og hydrofile komponenter |
Country Status (10)
Country | Link |
---|---|
US (4) | US6388047B1 (fr) |
EP (1) | EP1168934B1 (fr) |
JP (1) | JP4558213B2 (fr) |
AT (1) | ATE386075T1 (fr) |
AU (1) | AU3877200A (fr) |
CA (1) | CA2368617C (fr) |
DE (1) | DE60038010T2 (fr) |
DK (1) | DK1168934T3 (fr) |
ES (1) | ES2298135T3 (fr) |
WO (1) | WO2000060956A1 (fr) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE386075T1 (de) * | 1999-04-12 | 2008-03-15 | Cornell Res Foundation Inc | Hydrogel-formendes system mit hydrophoben und hydrophilen komponenten |
US6716445B2 (en) * | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
CA2450123C (fr) | 2001-08-02 | 2013-01-29 | Cornell Research Foundation, Inc. | Esters d'alcool polyhydrique biodegradables |
US20050064587A1 (en) * | 2001-09-07 | 2005-03-24 | Lawrence Rosenberg | Pancreatic small cells and uses thereof |
US7037983B2 (en) | 2002-06-14 | 2006-05-02 | Kimberly-Clark Worldwide, Inc. | Methods of making functional biodegradable polymers |
JP3742842B2 (ja) * | 2002-06-17 | 2006-02-08 | 独立行政法人産業技術総合研究所 | 生分解性ポリ乳酸樹脂組成物 |
US7744913B2 (en) * | 2002-06-24 | 2010-06-29 | Incept, Llc | Fillers and methods for displacing tissues to improve radiological outcomes |
AU2002950340A0 (en) * | 2002-07-23 | 2002-09-12 | Commonwealth Scientific And Industrial Research Organisation | Biodegradable polyurethane/urea compositions |
AU2003254674A1 (en) * | 2002-08-09 | 2004-02-25 | National Research Council Of Canada | Bio-synthetic matrix and uses thereof |
EP1549255A4 (fr) * | 2002-09-13 | 2007-12-19 | Coopervision Inc | Dispositifs et procedes pour ameliorer la vision |
JP2006515640A (ja) * | 2003-01-16 | 2006-06-01 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 部分的に生分解可能な温度およびpH感受性ヒドロゲル |
WO2004085712A2 (fr) * | 2003-03-24 | 2004-10-07 | Penn State Research Foundation | Materiaux polymeres multifonctionnels et leurs utilisations |
JP2007509716A (ja) * | 2003-10-29 | 2007-04-19 | ジェンティス インコーポレイテッド | 組織工学用の重合可能なエマルション |
US20050119762A1 (en) * | 2003-11-03 | 2005-06-02 | Peter Zilla | Hydrogel providing cell-specific ingrowth |
JP2007526942A (ja) * | 2004-03-03 | 2007-09-20 | コモンウエルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション | 二段階又は多段階硬化のための生体適合性ポリマー組成物 |
CN101052672A (zh) * | 2004-03-17 | 2007-10-10 | 伯乐实验室有限公司 | 光交联的水凝胶共混物表面涂层 |
JP2007530169A (ja) | 2004-03-26 | 2007-11-01 | サーモディクス,インコーポレイティド | 生物適合性表面を調製するための組成物及び方法 |
GB0407661D0 (en) * | 2004-04-03 | 2004-05-05 | Univ Hull | Liquid crystalline interpenetrating polymer networks |
JP4599550B2 (ja) * | 2004-04-09 | 2010-12-15 | 国立大学法人 東京医科歯科大学 | ナノゲル工学によるハイブリッドゲルの調製とバイオマテリアル応用 |
CA2564588A1 (fr) * | 2004-05-12 | 2005-12-01 | Surmodics, Inc. | Revetements comprenant des polysaccharides biodegradables naturels pour articles medicaux |
US8246993B2 (en) | 2004-06-10 | 2012-08-21 | Cytogel Pharma, Llc | Advantageous hydrogel composition |
US7446131B1 (en) | 2004-06-10 | 2008-11-04 | The United States Of America As Represented By The Secretary Of Agriculture | Porous polymeric matrices made of natural polymers and synthetic polymers and optionally at least one cation and methods of making |
US20060013886A1 (en) | 2004-06-28 | 2006-01-19 | Daqing Wu | Injectable microspheres |
US7235592B2 (en) * | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
AU2006216655B2 (en) * | 2005-02-23 | 2012-05-31 | Zimmer Technology, Inc. | Blend hydrogels and methods of making |
US20060222596A1 (en) | 2005-04-01 | 2006-10-05 | Trivascular, Inc. | Non-degradable, low swelling, water soluble radiopaque hydrogel polymer |
WO2007033418A1 (fr) | 2005-09-20 | 2007-03-29 | Polynovo Biomaterials Pty Limited | Allongeurs de chaîne |
US8241656B2 (en) * | 2005-09-21 | 2012-08-14 | Surmodics, Inc | Articles including natural biodegradable polysaccharides and uses thereof |
US20070065484A1 (en) * | 2005-09-21 | 2007-03-22 | Chudzik Stephen J | In situ occlusion using natural biodegradable polysaccharides |
US20070098799A1 (en) * | 2005-10-28 | 2007-05-03 | Zimmer, Inc. | Mineralized Hydrogels and Methods of Making and Using Hydrogels |
CA2632120C (fr) * | 2005-12-07 | 2014-07-08 | Zimmer, Inc. | Procedes de liaison ou de modification d'hydrogels par irradiation |
US20070141108A1 (en) * | 2005-12-20 | 2007-06-21 | Zimmer, Inc. | Fiber-reinforced water-swellable articles |
US8017107B2 (en) * | 2005-12-22 | 2011-09-13 | Zimmer, Inc. | Perfluorocyclobutane crosslinked hydrogels |
WO2007092550A2 (fr) * | 2006-02-08 | 2007-08-16 | Coopervision Inc. | Onlays corneens et procedes apparentes |
CN101405303B (zh) * | 2006-03-14 | 2011-11-23 | 诺维信生物制药丹麦公司 | 丙烯酸酯化的透明质酸 |
US8110242B2 (en) * | 2006-03-24 | 2012-02-07 | Zimmer, Inc. | Methods of preparing hydrogel coatings |
US8795709B2 (en) | 2006-03-29 | 2014-08-05 | Incept Llc | Superabsorbent, freeze dried hydrogels for medical applications |
US7812098B2 (en) * | 2006-03-31 | 2010-10-12 | Depuy Products, Inc. | Bearing material of medical implant having reduced wear rate and method for reducing wear rate |
US20070232762A1 (en) * | 2006-03-31 | 2007-10-04 | Depuy Products, Inc. | Bearing material of medical implant having reduced wear rate and method for reducing wear rate |
US7883520B2 (en) * | 2006-04-10 | 2011-02-08 | Forsight Labs, Llc | Corneal epithelial pocket formation systems, components and methods |
US7872068B2 (en) * | 2006-05-30 | 2011-01-18 | Incept Llc | Materials formable in situ within a medical device |
AU2007281035A1 (en) * | 2006-08-02 | 2008-02-07 | Polynovo Biomaterials Pty Ltd | Biocompatible polymer compositions |
US20080075785A1 (en) * | 2006-09-22 | 2008-03-27 | San-Laung Chow | Controlled release hydrogel formulation |
US20110165236A1 (en) * | 2006-09-22 | 2011-07-07 | Biokey, Inc. | Controlled release hydrogel formulation |
WO2008073295A2 (fr) * | 2006-12-07 | 2008-06-19 | Surmodics, Inc. | Stabilisation latente d'agents biologiquement actifs libérables à partir d'articles médicaux implantables |
US9125807B2 (en) | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
US7731988B2 (en) | 2007-08-03 | 2010-06-08 | Zimmer, Inc. | Multi-polymer hydrogels |
US20090043398A1 (en) * | 2007-08-09 | 2009-02-12 | Zimmer, Inc. | Method of producing gradient articles by centrifugation molding or casting |
US20110136935A1 (en) * | 2007-08-30 | 2011-06-09 | National University Of Singapore | Bone and/or dental cement composition and uses thereof |
US8062739B2 (en) * | 2007-08-31 | 2011-11-22 | Zimmer, Inc. | Hydrogels with gradient |
US8357767B2 (en) * | 2007-10-03 | 2013-01-22 | Polynovo Biomaterials Limited | High modulus polyurethane and polyurethane/urea compositions |
US7947784B2 (en) | 2007-11-16 | 2011-05-24 | Zimmer, Inc. | Reactive compounding of hydrogels |
US8034362B2 (en) * | 2008-01-04 | 2011-10-11 | Zimmer, Inc. | Chemical composition of hydrogels for use as articulating surfaces |
MX2010010663A (es) | 2008-03-28 | 2010-11-09 | Surmodics Inc | Dispositivos medicos insertables que tienen substratos elasticos asociados con microparticulas, y metodos de suministro de farmacos. |
WO2009137689A2 (fr) | 2008-05-07 | 2009-11-12 | Surmodics, Inc. | Administration de complexe d’acide nucléique à partir de particules |
US20100087920A1 (en) * | 2008-10-07 | 2010-04-08 | Forsight Labs, Llc | Corneal Onlay Lenses and Related Methods for Improving Vision of Presbyopic Patients |
AU2010213612B2 (en) | 2009-02-12 | 2015-04-30 | Incept, Llc | Drug delivery through hydrogel plugs |
CA2977830C (fr) | 2009-05-04 | 2019-09-17 | Incept, Llc | Biomateriaux pour la fermeture de voie et de ponction |
JP2012235797A (ja) | 2009-09-18 | 2012-12-06 | Terumo Corp | ステント |
US8795727B2 (en) | 2009-11-09 | 2014-08-05 | Spotlight Technology Partners Llc | Fragmented hydrogels |
NZ599524A (en) | 2009-11-09 | 2014-04-30 | Spotlight Technology Partners Llc | Polysaccharide based hydrogels |
CA3042067C (fr) | 2009-12-15 | 2022-10-18 | Incept, Llc | Implants et marqueurs de reference biodegradables |
WO2011146922A2 (fr) | 2010-05-21 | 2011-11-24 | Cytogel Pharma, Llc | Matériels et méthodes pour traitement d'une inflammation |
US8961501B2 (en) | 2010-09-17 | 2015-02-24 | Incept, Llc | Method for applying flowable hydrogels to a cornea |
US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
CA3149018A1 (fr) | 2011-07-18 | 2013-01-24 | President And Fellows Of Harvard College | Molecules manipulees ciblant un microbe et leurs utilisations |
US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
RU2521194C2 (ru) * | 2011-11-16 | 2014-06-27 | Общество с ограниченной ответственностью предприятие "Репер" | Матрица для клеточной трансплантологии |
CA2858161C (fr) | 2011-12-05 | 2020-03-10 | Incept, Llc | Procedes et compositions associes a un organogel medical |
CN105188667A (zh) * | 2013-03-27 | 2015-12-23 | 佛多斯大学医学研究中心(C·H·U·V) | 用于治疗和/或预防再狭窄的药物制剂 |
EP3848044A1 (fr) | 2013-05-21 | 2021-07-14 | President and Fellows of Harvard College | Compositions se liant à l'hème manipulées et leurs utilisations |
WO2015095604A2 (fr) | 2013-12-18 | 2015-06-25 | President And Fellows Of Harvard College | Méthodes et analyses associées à des cellules tumorales circulantes |
US10519443B2 (en) | 2014-09-08 | 2019-12-31 | University Of Iowa Research Foundation | Microrna inhibitor system and methods of use thereof |
EP3331549B1 (fr) | 2015-08-06 | 2020-12-23 | President and Fellows of Harvard College | Molécules améliorées aptes à se lier à des microbes, et leurs utilisations |
US10273476B2 (en) | 2016-04-30 | 2019-04-30 | University Of Iowa Research Foundation | MicroRNA-200 based approaches for modulating bone formation inhibition and bone regeneration |
ES2887376T3 (es) * | 2016-12-16 | 2021-12-22 | Procter & Gamble | Derivados de polisacáridos anfifílicos y composiciones que los comprenden |
CN106913915B (zh) * | 2017-04-21 | 2019-05-31 | 浙江大学 | 一种自愈合支架复合涂层及其制备方法和应用 |
CN107216450B (zh) * | 2017-04-21 | 2019-06-11 | 浙江大学 | 一种自愈合抗菌涂层及其制备方法和应用 |
US10975121B2 (en) | 2017-06-24 | 2021-04-13 | Cytogel Pharma, Llc | Analgesic mu-opioid receptor binding peptide pharmaceutical formulations and uses thereof |
CN110108537B (zh) * | 2018-02-01 | 2020-08-25 | 中国科学技术大学 | 一种用于生物组织包埋的包埋剂和包埋方法 |
CN108359054A (zh) * | 2018-02-10 | 2018-08-03 | 西北大学 | 一种葡萄糖敏感型全互穿网络水凝胶及其制备方法 |
CN116496475B (zh) * | 2023-06-26 | 2023-09-22 | 海杰亚(北京)医疗器械有限公司 | 用于栓塞微球的可降解交联剂、可降解栓塞微球及其制备方法和药物组合物 |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4002173A (en) | 1974-07-23 | 1977-01-11 | International Paper Company | Diester crosslinked polyglucan hydrogels and reticulated sponges thereof |
US4032488A (en) * | 1975-10-03 | 1977-06-28 | Meito Sangyo Kabushiki Kaisha | Dextran ester-olefin compound copolymer and process for preparing same |
SU729197A1 (ru) * | 1977-07-05 | 1980-04-25 | Ордена Ленина Институт Элементоорганических Соединений Ан Ссср | Сшитые сополимеры хитозана |
US4277582A (en) * | 1978-03-03 | 1981-07-07 | Ciba-Geigy Corporation | Water-insoluble hydrophilic copolymers |
GB8418772D0 (en) | 1984-07-24 | 1984-08-30 | Geistlich Soehne Ag | Chemical substances |
US4857602A (en) * | 1986-09-05 | 1989-08-15 | American Cyanamid Company | Bioabsorbable surgical suture coating |
US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5529914A (en) * | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
US5626863A (en) | 1992-02-28 | 1997-05-06 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
US5410016A (en) * | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
US5210111A (en) * | 1991-08-22 | 1993-05-11 | Ciba-Geigy Corporation | Crosslinked hydrogels derived from hydrophilic polymer backbones |
AU3124793A (en) * | 1991-10-29 | 1993-06-07 | Clover Consolidated, Limited | Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release |
ATE192487T1 (de) | 1992-02-13 | 2000-05-15 | Surmodics Inc | Immobilisierung eines chemischen spezies in einer vernetzten matrix |
WO1993017669A1 (fr) | 1992-02-28 | 1993-09-16 | Board Of Regents, The University Of Texas System | Hydrogels biodegradables, polymerisables utilises en tant que materiaux en contact avec des tissus et excipients a liberation controlee |
US5573934A (en) | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
IT1260154B (it) | 1992-07-03 | 1996-03-28 | Lanfranco Callegaro | Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn) |
US5514379A (en) | 1992-08-07 | 1996-05-07 | The General Hospital Corporation | Hydrogel compositions and methods of use |
US5488102A (en) | 1992-11-30 | 1996-01-30 | Ciba Geigy Corporation | Polymerisable carbohydrate esters, polymers therefrom and their use |
KR0141431B1 (ko) | 1994-05-17 | 1998-07-01 | 김상웅 | 생분해성 하이드로겔 고분자 |
TW291481B (en) * | 1994-10-27 | 1996-11-21 | Novartis Erfind Verwalt Gmbh | Poly-unsaturated carbohydrate derivatives, polymers thereof and their use |
US5607686A (en) | 1994-11-22 | 1997-03-04 | United States Surgical Corporation | Polymeric composition |
US5540929A (en) | 1995-03-08 | 1996-07-30 | Board Of Trustees Operating Michigan State University | Polysaccharides grafted with aliphatic polyesters derived from cyclic esters |
US5900245A (en) | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
ATE342295T1 (de) * | 1995-07-28 | 2006-11-15 | Genzyme Corp | Biologische abbaubare multiblokhydrogene und ihre verwendung wie trägerstoffe fur kontrollierte freisetzung pharmakologisch activen werstoffe und gewebekontaktmaterialen |
JP3572144B2 (ja) * | 1996-05-31 | 2004-09-29 | 名糖産業株式会社 | デキストランエステル共重合体 |
US5854382A (en) * | 1997-08-18 | 1998-12-29 | Meadox Medicals, Inc. | Bioresorbable compositions for implantable prostheses |
US6107365A (en) * | 1997-09-03 | 2000-08-22 | The Regents Of The University Of California | Biomimetic hydrogel materials |
AU5571399A (en) * | 1998-08-31 | 2000-03-21 | Cornell Research Foundation Inc. | Dextran-maleic acid monoesters and hydrogels based thereon |
ATE386075T1 (de) * | 1999-04-12 | 2008-03-15 | Cornell Res Foundation Inc | Hydrogel-formendes system mit hydrophoben und hydrophilen komponenten |
US6716445B2 (en) * | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
AU766394B2 (en) * | 1999-09-02 | 2003-10-16 | Alcon Inc. | Hydrophobically-bound, hydrophilic coating compositions for surgical implants |
US6503538B1 (en) | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
CA2450123C (fr) * | 2001-08-02 | 2013-01-29 | Cornell Research Foundation, Inc. | Esters d'alcool polyhydrique biodegradables |
-
2000
- 2000-03-20 AT AT00917865T patent/ATE386075T1/de not_active IP Right Cessation
- 2000-03-20 WO PCT/US2000/006416 patent/WO2000060956A1/fr active IP Right Grant
- 2000-03-20 JP JP2000610306A patent/JP4558213B2/ja not_active Expired - Fee Related
- 2000-03-20 CA CA2368617A patent/CA2368617C/fr not_active Expired - Fee Related
- 2000-03-20 AU AU38772/00A patent/AU3877200A/en not_active Abandoned
- 2000-03-20 DK DK00917865T patent/DK1168934T3/da active
- 2000-03-20 DE DE60038010T patent/DE60038010T2/de not_active Expired - Lifetime
- 2000-03-20 ES ES00917865T patent/ES2298135T3/es not_active Expired - Lifetime
- 2000-03-20 EP EP00917865A patent/EP1168934B1/fr not_active Expired - Lifetime
- 2000-03-20 US US09/531,451 patent/US6388047B1/en not_active Expired - Lifetime
-
2002
- 2002-03-13 US US10/096,435 patent/US6583219B2/en not_active Expired - Fee Related
-
2003
- 2003-02-21 US US10/369,676 patent/US6709668B2/en not_active Expired - Fee Related
- 2003-12-12 US US10/733,291 patent/US6916857B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4558213B2 (ja) | 2010-10-06 |
WO2000060956A1 (fr) | 2000-10-19 |
EP1168934A4 (fr) | 2004-12-08 |
US6709668B2 (en) | 2004-03-23 |
US20020161169A1 (en) | 2002-10-31 |
DE60038010T2 (de) | 2009-03-05 |
DE60038010D1 (de) | 2008-03-27 |
CA2368617A1 (fr) | 2000-10-19 |
US20030125509A1 (en) | 2003-07-03 |
EP1168934B1 (fr) | 2008-02-13 |
AU3877200A (en) | 2000-11-14 |
ES2298135T3 (es) | 2008-05-16 |
CA2368617C (fr) | 2010-03-16 |
JP2002541308A (ja) | 2002-12-03 |
US20040122165A1 (en) | 2004-06-24 |
US6388047B1 (en) | 2002-05-14 |
US6583219B2 (en) | 2003-06-24 |
ATE386075T1 (de) | 2008-03-15 |
US6916857B2 (en) | 2005-07-12 |
EP1168934A1 (fr) | 2002-01-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1168934T3 (da) | Hydrogeldannende system med hydrofobe og hydrofile komponenter | |
ATE238068T1 (de) | Hydrolysierbare hydrogele zur gesteuerten freisetzung | |
FI103381B1 (fi) | Hyaluronihapon veteen liukenemattomia geelejä ja menetelmä sen valmistamiseksi | |
AU640927B2 (en) | Water soluble high molecular polymerized drug preparation | |
MD20020072A (en) | Combination of antibiotic(s) - polymer and utilization there of | |
AU590565B2 (en) | Controlled release delivery system for macromolecules | |
AR019608A1 (es) | Polimero absorbente, procedimiento para su preparacion, y su aplicacion | |
DE3751647D1 (de) | Biologisch abbaubare Mikrokugeln als Träger für Makromoleküle | |
MX193604B (es) | Hidrogeles hidrofilicos altamente hinchables | |
WO2002087001A3 (fr) | Membrane a electrolyte polymere | |
BR9206222A (pt) | Catalisador de ácido de lewis imobilizado de preparação de um catalisador imobilizado moldado, processo para polimerizar monômero cationicamente polimerizável, composição e polímero cationicamente polimerizado. | |
ES547195A0 (es) | Un procedimiento para la preparacion de un polisilaxano macromero con grupos polimerizables no saturados. | |
AU8679198A (en) | Modified polylactide compositions, water-responsive, biodegradable films and fibers comprising polylactide and poly(vinyl alcohol) and methods for making the same | |
TW200502011A (en) | Superabsorbent polymer with high permeability | |
AU5061999A (en) | Slow release formulations comprising anionic polysaccharide | |
JP2006504990A (ja) | 成型物ならびにその製造および用途 | |
AU697005B2 (en) | Implantable molded articles for the administration of active substances to plants | |
ATE410473T1 (de) | Polymerstrukturen mit einem hydrophil/lipophil- system | |
ZA957471B (en) | Contrast agents | |
MXPA03011263A (es) | Macromeros reticulables. | |
AU2001268964A1 (en) | Polysaccharide - based superabsorbent film | |
ATE239042T1 (de) | Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert ist | |
WO2005065712A3 (fr) | Complexes presentant une activite d'adjuvant | |
BR0014638A (pt) | Composição polimérica superabsorvente, artigo absorvente, e processo para preparar um artigo absorvente | |
AU8085691A (en) | Activation of polysaccharide hydrolase |