DK1168934T3 - Hydrogeldannende system med hydrofobe og hydrofile komponenter - Google Patents
Hydrogeldannende system med hydrofobe og hydrofile komponenterInfo
- Publication number
- DK1168934T3 DK1168934T3 DK00917865T DK00917865T DK1168934T3 DK 1168934 T3 DK1168934 T3 DK 1168934T3 DK 00917865 T DK00917865 T DK 00917865T DK 00917865 T DK00917865 T DK 00917865T DK 1168934 T3 DK1168934 T3 DK 1168934T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydrophobic
- forming system
- hydrophilic components
- hydrogel forming
- unsaturated group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/02—Dextran; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
- C08G18/6484—Polysaccharides and derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/81—Unsaturated isocyanates or isothiocyanates
- C08G18/8108—Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/06—Unsaturated polyesters
- C08L67/07—Unsaturated polyesters having terminal carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2210/00—Compositions for preparing hydrogels
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
- Y10S525/937—Utility as body contact e.g. implant, contact lens or I.U.D.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Colloid Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Graft Or Block Polymers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12880399P | 1999-04-12 | 1999-04-12 | |
PCT/US2000/006416 WO2000060956A1 (en) | 1999-04-12 | 2000-03-20 | Hydrogel-forming system with hydrophobic and hydrophilic components |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1168934T3 true DK1168934T3 (da) | 2008-05-13 |
Family
ID=22437052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00917865T DK1168934T3 (da) | 1999-04-12 | 2000-03-20 | Hydrogeldannende system med hydrofobe og hydrofile komponenter |
Country Status (10)
Country | Link |
---|---|
US (4) | US6388047B1 (da) |
EP (1) | EP1168934B1 (da) |
JP (1) | JP4558213B2 (da) |
AT (1) | ATE386075T1 (da) |
AU (1) | AU3877200A (da) |
CA (1) | CA2368617C (da) |
DE (1) | DE60038010T2 (da) |
DK (1) | DK1168934T3 (da) |
ES (1) | ES2298135T3 (da) |
WO (1) | WO2000060956A1 (da) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1168934T3 (da) | 1999-04-12 | 2008-05-13 | Cornell Res Foundation Inc | Hydrogeldannende system med hydrofobe og hydrofile komponenter |
US6716445B2 (en) * | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
JP4335002B2 (ja) * | 2001-08-02 | 2009-09-30 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 生分解性多価アルコールエステル |
US20050064587A1 (en) * | 2001-09-07 | 2005-03-24 | Lawrence Rosenberg | Pancreatic small cells and uses thereof |
US7037983B2 (en) | 2002-06-14 | 2006-05-02 | Kimberly-Clark Worldwide, Inc. | Methods of making functional biodegradable polymers |
JP3742842B2 (ja) * | 2002-06-17 | 2006-02-08 | 独立行政法人産業技術総合研究所 | 生分解性ポリ乳酸樹脂組成物 |
ES2424348T3 (es) * | 2002-06-24 | 2013-10-01 | Incept, Llc | Cargas y métodos para desplazar tejidos para mejorar los resultados radiológicos |
AU2002950340A0 (en) * | 2002-07-23 | 2002-09-12 | Commonwealth Scientific And Industrial Research Organisation | Biodegradable polyurethane/urea compositions |
KR101053792B1 (ko) * | 2002-08-09 | 2011-08-04 | 내셔날 리서치 카운실 오브 캐나다 | 생체 합성 매트릭스 및 그의 용도 |
AU2003270593A1 (en) * | 2002-09-13 | 2004-04-30 | Ocular Sciences, Inc. | Devices and methods for improving vision |
EP1583520A4 (en) * | 2003-01-16 | 2007-05-23 | Cornell Res Foundation Inc | PARTIALLY BIODEGRADABLE HYDROGEL SENSITIVE TO TEMPERATURE AND PH |
WO2004085712A2 (en) | 2003-03-24 | 2004-10-07 | Penn State Research Foundation | Multi-functional polymeric materials and their uses |
JP2007509716A (ja) * | 2003-10-29 | 2007-04-19 | ジェンティス インコーポレイテッド | 組織工学用の重合可能なエマルション |
ATE524203T1 (de) * | 2003-11-03 | 2011-09-15 | Medtronic Inc | Hydrogel für zellspezifisches einwachsen |
US8729202B2 (en) * | 2004-03-03 | 2014-05-20 | Polynovo Biomaterials Pty Limited | Biocompatible polymer compositions for dual or multi staged curing |
CA2560016A1 (en) * | 2004-03-17 | 2005-10-13 | Ciphergen Biosystems, Inc. | Photocrosslinked hydrogel blend surface coatings |
EP2329852A1 (en) | 2004-03-26 | 2011-06-08 | SurModics, Inc. | Composition and method for preparing biocompatible surfaces |
GB0407661D0 (en) * | 2004-04-03 | 2004-05-05 | Univ Hull | Liquid crystalline interpenetrating polymer networks |
JP4599550B2 (ja) * | 2004-04-09 | 2010-12-15 | 国立大学法人 東京医科歯科大学 | ナノゲル工学によるハイブリッドゲルの調製とバイオマテリアル応用 |
CA2564588A1 (en) * | 2004-05-12 | 2005-12-01 | Surmodics, Inc. | Natural biodegradable polysaccharide coatings for medical articles |
US7446131B1 (en) | 2004-06-10 | 2008-11-04 | The United States Of America As Represented By The Secretary Of Agriculture | Porous polymeric matrices made of natural polymers and synthetic polymers and optionally at least one cation and methods of making |
US8246993B2 (en) | 2004-06-10 | 2012-08-21 | Cytogel Pharma, Llc | Advantageous hydrogel composition |
US20060013886A1 (en) | 2004-06-28 | 2006-01-19 | Daqing Wu | Injectable microspheres |
US7235592B2 (en) * | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
WO2006091706A1 (en) * | 2005-02-23 | 2006-08-31 | Zimmer Technology, Inc. | Blend hydrogels and methods of making |
US20060222596A1 (en) | 2005-04-01 | 2006-10-05 | Trivascular, Inc. | Non-degradable, low swelling, water soluble radiopaque hydrogel polymer |
WO2007033418A1 (en) | 2005-09-20 | 2007-03-29 | Polynovo Biomaterials Pty Limited | Chain extenders |
WO2007040557A1 (en) * | 2005-09-21 | 2007-04-12 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
US20070071792A1 (en) * | 2005-09-21 | 2007-03-29 | Varner Signe E | In VIVO formed matrices including natural biodegradale polysaccharides and ophthalmic uses thereof |
US20070098799A1 (en) * | 2005-10-28 | 2007-05-03 | Zimmer, Inc. | Mineralized Hydrogels and Methods of Making and Using Hydrogels |
US8262730B2 (en) * | 2005-12-07 | 2012-09-11 | Zimmer, Inc. | Methods of bonding or modifying hydrogels using irradiation |
US20070141108A1 (en) * | 2005-12-20 | 2007-06-21 | Zimmer, Inc. | Fiber-reinforced water-swellable articles |
DE602006017160D1 (de) * | 2005-12-22 | 2010-11-11 | Zimmer Inc | Perfluorcyclobutanvernetzte Hydrogele |
TW200740416A (en) * | 2006-02-08 | 2007-11-01 | Coopervision Inc | Corneal onlays and related methods |
ES2339181T3 (es) * | 2006-03-14 | 2010-05-17 | Novozymes Biopharma Dk A/S | Acido hialuronico acrilatado. |
US8110242B2 (en) * | 2006-03-24 | 2012-02-07 | Zimmer, Inc. | Methods of preparing hydrogel coatings |
US8795709B2 (en) | 2006-03-29 | 2014-08-05 | Incept Llc | Superabsorbent, freeze dried hydrogels for medical applications |
US7812098B2 (en) * | 2006-03-31 | 2010-10-12 | Depuy Products, Inc. | Bearing material of medical implant having reduced wear rate and method for reducing wear rate |
US20070232762A1 (en) * | 2006-03-31 | 2007-10-04 | Depuy Products, Inc. | Bearing material of medical implant having reduced wear rate and method for reducing wear rate |
US7883520B2 (en) * | 2006-04-10 | 2011-02-08 | Forsight Labs, Llc | Corneal epithelial pocket formation systems, components and methods |
US7872068B2 (en) * | 2006-05-30 | 2011-01-18 | Incept Llc | Materials formable in situ within a medical device |
AU2007281035A1 (en) * | 2006-08-02 | 2008-02-07 | Polynovo Biomaterials Pty Ltd | Biocompatible polymer compositions |
US20080075785A1 (en) * | 2006-09-22 | 2008-03-27 | San-Laung Chow | Controlled release hydrogel formulation |
US20110165236A1 (en) * | 2006-09-22 | 2011-07-07 | Biokey, Inc. | Controlled release hydrogel formulation |
US20080154241A1 (en) * | 2006-12-07 | 2008-06-26 | Burkstrand Michael J | Latent stabilization of bioactive agents releasable from implantable medical articles |
US9125807B2 (en) | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
US7731988B2 (en) | 2007-08-03 | 2010-06-08 | Zimmer, Inc. | Multi-polymer hydrogels |
US20090043398A1 (en) * | 2007-08-09 | 2009-02-12 | Zimmer, Inc. | Method of producing gradient articles by centrifugation molding or casting |
US20110136935A1 (en) * | 2007-08-30 | 2011-06-09 | National University Of Singapore | Bone and/or dental cement composition and uses thereof |
US8062739B2 (en) * | 2007-08-31 | 2011-11-22 | Zimmer, Inc. | Hydrogels with gradient |
CN101896526B (zh) * | 2007-10-03 | 2013-09-11 | 新型聚合物生物材料有限公司 | 高模量聚氨酯和聚氨酯/脲组合物 |
US7947784B2 (en) | 2007-11-16 | 2011-05-24 | Zimmer, Inc. | Reactive compounding of hydrogels |
US8034362B2 (en) * | 2008-01-04 | 2011-10-11 | Zimmer, Inc. | Chemical composition of hydrogels for use as articulating surfaces |
JP5667559B2 (ja) | 2008-03-28 | 2015-02-12 | サーモディクス,インコーポレイティド | 微粒子が配置された弾性基質を有する挿入可能な医療機器、および薬物送達方法 |
CA2723192A1 (en) | 2008-05-07 | 2009-11-12 | Surmodics, Inc. | Delivery of nucleic acid complexes from particles |
US20100087920A1 (en) * | 2008-10-07 | 2010-04-08 | Forsight Labs, Llc | Corneal Onlay Lenses and Related Methods for Improving Vision of Presbyopic Patients |
CA2750242C (en) | 2009-02-12 | 2018-05-22 | Incept, Llc | Drug delivery through hydrogel plugs |
EP2427233B1 (en) | 2009-05-04 | 2016-12-21 | Incept Llc | Biomaterials for track and puncture closure |
JP2012235797A (ja) | 2009-09-18 | 2012-12-06 | Terumo Corp | ステント |
CA2780294C (en) | 2009-11-09 | 2018-01-16 | Spotlight Technology Partners Llc | Polysaccharide based hydrogels |
CA2780274C (en) | 2009-11-09 | 2018-06-26 | Spotlight Technology Partners Llc | Fragmented hydrogels |
EP3960215B1 (en) | 2009-12-15 | 2024-10-16 | Incept, LLC | Implants and biodegradable fiducial markers |
EP2574172A4 (en) | 2010-05-21 | 2013-10-30 | Cytogel Pharma Llc | MATERIALS AND METHOD FOR TREATING INFLAMMATION |
US8961501B2 (en) | 2010-09-17 | 2015-02-24 | Incept, Llc | Method for applying flowable hydrogels to a cornea |
US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
CA2842321C (en) | 2011-07-18 | 2022-05-03 | President And Fellows Of Harvard College | Engineered microbe-targeting molecules and uses thereof |
US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
RU2521194C2 (ru) * | 2011-11-16 | 2014-06-27 | Общество с ограниченной ответственностью предприятие "Репер" | Матрица для клеточной трансплантологии |
AU2012347926B2 (en) | 2011-12-05 | 2018-03-15 | Incept, Llc | Medical organogel processes and compositions |
WO2014154804A1 (en) * | 2013-03-27 | 2014-10-02 | Centre Hospitalier Universitaire Vaudois (C.H.U.V) | Pharmaceutical formulation for use in the treatment and/or prevention of restenosis |
CA2913155A1 (en) | 2013-05-21 | 2014-11-27 | President And Fellows Of Harvard College | Engineered heme-binding compositions and uses thereof |
EP3083658B1 (en) | 2013-12-18 | 2019-05-08 | President and Fellows of Harvard College | Crp capture/detection of gram positive bacteria |
US10519443B2 (en) | 2014-09-08 | 2019-12-31 | University Of Iowa Research Foundation | Microrna inhibitor system and methods of use thereof |
EP3763378A1 (en) | 2015-08-06 | 2021-01-13 | President and Fellows of Harvard College | Improved microbe-binding molecules and uses thereof |
US10273476B2 (en) | 2016-04-30 | 2019-04-30 | University Of Iowa Research Foundation | MicroRNA-200 based approaches for modulating bone formation inhibition and bone regeneration |
ES2887376T3 (es) * | 2016-12-16 | 2021-12-22 | Procter & Gamble | Derivados de polisacáridos anfifílicos y composiciones que los comprenden |
CN106913915B (zh) * | 2017-04-21 | 2019-05-31 | 浙江大学 | 一种自愈合支架复合涂层及其制备方法和应用 |
CN107216450B (zh) * | 2017-04-21 | 2019-06-11 | 浙江大学 | 一种自愈合抗菌涂层及其制备方法和应用 |
US10975121B2 (en) | 2017-06-24 | 2021-04-13 | Cytogel Pharma, Llc | Analgesic mu-opioid receptor binding peptide pharmaceutical formulations and uses thereof |
CN110108537B (zh) * | 2018-02-01 | 2020-08-25 | 中国科学技术大学 | 一种用于生物组织包埋的包埋剂和包埋方法 |
CN108359054A (zh) * | 2018-02-10 | 2018-08-03 | 西北大学 | 一种葡萄糖敏感型全互穿网络水凝胶及其制备方法 |
CN116496475B (zh) * | 2023-06-26 | 2023-09-22 | 海杰亚(北京)医疗器械有限公司 | 用于栓塞微球的可降解交联剂、可降解栓塞微球及其制备方法和药物组合物 |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4002173A (en) | 1974-07-23 | 1977-01-11 | International Paper Company | Diester crosslinked polyglucan hydrogels and reticulated sponges thereof |
US4032488A (en) * | 1975-10-03 | 1977-06-28 | Meito Sangyo Kabushiki Kaisha | Dextran ester-olefin compound copolymer and process for preparing same |
SU729197A1 (ru) * | 1977-07-05 | 1980-04-25 | Ордена Ленина Институт Элементоорганических Соединений Ан Ссср | Сшитые сополимеры хитозана |
US4277582A (en) * | 1978-03-03 | 1981-07-07 | Ciba-Geigy Corporation | Water-insoluble hydrophilic copolymers |
GB8418772D0 (en) | 1984-07-24 | 1984-08-30 | Geistlich Soehne Ag | Chemical substances |
US4857602A (en) * | 1986-09-05 | 1989-08-15 | American Cyanamid Company | Bioabsorbable surgical suture coating |
US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5626863A (en) | 1992-02-28 | 1997-05-06 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
US5410016A (en) | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
US5529914A (en) * | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
US5210111A (en) * | 1991-08-22 | 1993-05-11 | Ciba-Geigy Corporation | Crosslinked hydrogels derived from hydrophilic polymer backbones |
JPH07503943A (ja) | 1991-10-29 | 1995-04-27 | クローバー コンソリデイテッド,リミテッド | 封入及び薬剤放出に有用な架橋性の多糖類、ポリカチオン及び脂質 |
JP3455217B2 (ja) * | 1992-02-13 | 2003-10-14 | バイオ−メトリック システムズ インコーポレイテッド | 架橋マトリックス中の化学種の固定 |
PT627911E (pt) | 1992-02-28 | 2001-04-30 | Univ Texas | Hidrogeis biodegradaveis fotopolimerizaveis como materiais de contacto de tecidos e veiculos de libertacao controlada |
US5573934A (en) * | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
IT1260154B (it) | 1992-07-03 | 1996-03-28 | Lanfranco Callegaro | Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn) |
US5514379A (en) | 1992-08-07 | 1996-05-07 | The General Hospital Corporation | Hydrogel compositions and methods of use |
ES2102186T3 (es) | 1992-11-30 | 1997-07-16 | Ciba Geigy Ag | Esteres de hidratos de carbono polimerizables, polimeros de los mismos y su empleo. |
KR0141431B1 (ko) | 1994-05-17 | 1998-07-01 | 김상웅 | 생분해성 하이드로겔 고분자 |
TW291481B (en) * | 1994-10-27 | 1996-11-21 | Novartis Erfind Verwalt Gmbh | Poly-unsaturated carbohydrate derivatives, polymers thereof and their use |
US5607686A (en) | 1994-11-22 | 1997-03-04 | United States Surgical Corporation | Polymeric composition |
US5540929A (en) | 1995-03-08 | 1996-07-30 | Board Of Trustees Operating Michigan State University | Polysaccharides grafted with aliphatic polyesters derived from cyclic esters |
US5900245A (en) * | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
JPH11510837A (ja) * | 1995-07-28 | 1999-09-21 | フォーカル,インコーポレイテッド | 薬物送達のための制御された放出薬剤および組織処置薬剤としての使用のためのマルチブロック生分解性ヒドロゲル |
JP3572144B2 (ja) * | 1996-05-31 | 2004-09-29 | 名糖産業株式会社 | デキストランエステル共重合体 |
US5854382A (en) * | 1997-08-18 | 1998-12-29 | Meadox Medicals, Inc. | Bioresorbable compositions for implantable prostheses |
AU9216998A (en) * | 1997-09-03 | 1999-03-22 | Regents Of The University Of California, The | Novel biomimetic hydrogel materials |
DE69925757T2 (de) * | 1998-08-31 | 2006-03-23 | Cornell Research Foundation, Inc. | Dextran-maleinsäuremonoester und hydrogele daraus |
DK1168934T3 (da) | 1999-04-12 | 2008-05-13 | Cornell Res Foundation Inc | Hydrogeldannende system med hydrofobe og hydrofile komponenter |
US6716445B2 (en) | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
WO2001015627A1 (en) * | 1999-09-02 | 2001-03-08 | Alcon Universal Ltd. | Hydrophobically-bound, hydrophilic coating compositions for surgical implants |
US6503538B1 (en) | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
JP4335002B2 (ja) | 2001-08-02 | 2009-09-30 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 生分解性多価アルコールエステル |
-
2000
- 2000-03-20 DK DK00917865T patent/DK1168934T3/da active
- 2000-03-20 WO PCT/US2000/006416 patent/WO2000060956A1/en active IP Right Grant
- 2000-03-20 EP EP00917865A patent/EP1168934B1/en not_active Expired - Lifetime
- 2000-03-20 AU AU38772/00A patent/AU3877200A/en not_active Abandoned
- 2000-03-20 AT AT00917865T patent/ATE386075T1/de not_active IP Right Cessation
- 2000-03-20 JP JP2000610306A patent/JP4558213B2/ja not_active Expired - Fee Related
- 2000-03-20 ES ES00917865T patent/ES2298135T3/es not_active Expired - Lifetime
- 2000-03-20 CA CA2368617A patent/CA2368617C/en not_active Expired - Fee Related
- 2000-03-20 US US09/531,451 patent/US6388047B1/en not_active Expired - Lifetime
- 2000-03-20 DE DE60038010T patent/DE60038010T2/de not_active Expired - Lifetime
-
2002
- 2002-03-13 US US10/096,435 patent/US6583219B2/en not_active Expired - Fee Related
-
2003
- 2003-02-21 US US10/369,676 patent/US6709668B2/en not_active Expired - Fee Related
- 2003-12-12 US US10/733,291 patent/US6916857B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20030125509A1 (en) | 2003-07-03 |
CA2368617C (en) | 2010-03-16 |
ES2298135T3 (es) | 2008-05-16 |
US20020161169A1 (en) | 2002-10-31 |
CA2368617A1 (en) | 2000-10-19 |
EP1168934A1 (en) | 2002-01-09 |
DE60038010D1 (de) | 2008-03-27 |
US6583219B2 (en) | 2003-06-24 |
WO2000060956A1 (en) | 2000-10-19 |
ATE386075T1 (de) | 2008-03-15 |
JP4558213B2 (ja) | 2010-10-06 |
US6388047B1 (en) | 2002-05-14 |
EP1168934A4 (en) | 2004-12-08 |
AU3877200A (en) | 2000-11-14 |
JP2002541308A (ja) | 2002-12-03 |
DE60038010T2 (de) | 2009-03-05 |
US20040122165A1 (en) | 2004-06-24 |
US6709668B2 (en) | 2004-03-23 |
EP1168934B1 (en) | 2008-02-13 |
US6916857B2 (en) | 2005-07-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1168934T3 (da) | Hydrogeldannende system med hydrofobe og hydrofile komponenter | |
ATE238068T1 (de) | Hydrolysierbare hydrogele zur gesteuerten freisetzung | |
FI103381B1 (fi) | Hyaluronihapon veteen liukenemattomia geelejä ja menetelmä sen valmistamiseksi | |
AU640927B2 (en) | Water soluble high molecular polymerized drug preparation | |
US7049351B2 (en) | Moldings and preparation and uses thereof | |
MD20020072A (en) | Combination of antibiotic(s) - polymer and utilization there of | |
AU590565B2 (en) | Controlled release delivery system for macromolecules | |
DE3751647D1 (de) | Biologisch abbaubare Mikrokugeln als Träger für Makromoleküle | |
MX193604B (es) | Hidrogeles hidrofilicos altamente hinchables | |
WO2002087001A3 (en) | Polymer electrolyte membrane | |
ES547195A0 (es) | Un procedimiento para la preparacion de un polisilaxano macromero con grupos polimerizables no saturados. | |
AU8679198A (en) | Modified polylactide compositions, water-responsive, biodegradable films and fibers comprising polylactide and poly(vinyl alcohol) and methods for making the same | |
AU697005B2 (en) | Implantable molded articles for the administration of active substances to plants | |
ZA957471B (en) | Contrast agents | |
MXPA03011263A (es) | Macromeros reticulables. | |
ATE239042T1 (de) | Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert ist | |
MXPA02009064A (es) | Pelicula superabsorbente a base de polisacarido.. | |
BR0014638A (pt) | Composição polimérica superabsorvente, artigo absorvente, e processo para preparar um artigo absorvente | |
ES481386A1 (es) | Procedimiento de preparacion de polimeros hidrosolubles. | |
AU8085691A (en) | Activation of polysaccharide hydrolase | |
EP0331052A3 (en) | Process for the preparation of imidized acrylic polymers | |
ES481385A1 (es) | Procedimiento de preparacion de polimeros organicos. | |
MX14264A (es) | Polimero de injerto soluble en alcali y procedimiento para su obtencion. | |
KR890016894A (ko) | 비스실록산 중합개시제를 이용한 중합체의 제조방법 | |
DE69109600D1 (de) | Zur Vernetzung geeignetes Ethene (Co)Polymer, seine Herstellung und Vernetzung. |