DK1168934T3 - Hydrogeldannende system med hydrofobe og hydrofile komponenter - Google Patents
Hydrogeldannende system med hydrofobe og hydrofile komponenterInfo
- Publication number
- DK1168934T3 DK1168934T3 DK00917865T DK00917865T DK1168934T3 DK 1168934 T3 DK1168934 T3 DK 1168934T3 DK 00917865 T DK00917865 T DK 00917865T DK 00917865 T DK00917865 T DK 00917865T DK 1168934 T3 DK1168934 T3 DK 1168934T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydrophobic
- forming system
- hydrophilic components
- hydrogel forming
- unsaturated group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/02—Dextran; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
- C08G18/6484—Polysaccharides and derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/81—Unsaturated isocyanates or isothiocyanates
- C08G18/8108—Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/06—Unsaturated polyesters
- C08L67/07—Unsaturated polyesters having terminal carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2210/00—Compositions for preparing hydrogels
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
- Y10S525/937—Utility as body contact e.g. implant, contact lens or I.U.D.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Colloid Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Graft Or Block Polymers (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12880399P | 1999-04-12 | 1999-04-12 | |
PCT/US2000/006416 WO2000060956A1 (en) | 1999-04-12 | 2000-03-20 | Hydrogel-forming system with hydrophobic and hydrophilic components |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1168934T3 true DK1168934T3 (da) | 2008-05-13 |
Family
ID=22437052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00917865T DK1168934T3 (da) | 1999-04-12 | 2000-03-20 | Hydrogeldannende system med hydrofobe og hydrofile komponenter |
Country Status (10)
Country | Link |
---|---|
US (4) | US6388047B1 (de) |
EP (1) | EP1168934B1 (de) |
JP (1) | JP4558213B2 (de) |
AT (1) | ATE386075T1 (de) |
AU (1) | AU3877200A (de) |
CA (1) | CA2368617C (de) |
DE (1) | DE60038010T2 (de) |
DK (1) | DK1168934T3 (de) |
ES (1) | ES2298135T3 (de) |
WO (1) | WO2000060956A1 (de) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6716445B2 (en) | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
WO2000060956A1 (en) * | 1999-04-12 | 2000-10-19 | Cornell Research Foundation, Inc. | Hydrogel-forming system with hydrophobic and hydrophilic components |
US6592895B2 (en) | 2001-08-02 | 2003-07-15 | Cornell Research Foundation, Inc. | Biodegradable polyhydric alcohol esters |
US20050064587A1 (en) * | 2001-09-07 | 2005-03-24 | Lawrence Rosenberg | Pancreatic small cells and uses thereof |
US7037983B2 (en) | 2002-06-14 | 2006-05-02 | Kimberly-Clark Worldwide, Inc. | Methods of making functional biodegradable polymers |
JP3742842B2 (ja) * | 2002-06-17 | 2006-02-08 | 独立行政法人産業技術総合研究所 | 生分解性ポリ乳酸樹脂組成物 |
US7744913B2 (en) * | 2002-06-24 | 2010-06-29 | Incept, Llc | Fillers and methods for displacing tissues to improve radiological outcomes |
AU2002950340A0 (en) | 2002-07-23 | 2002-09-12 | Commonwealth Scientific And Industrial Research Organisation | Biodegradable polyurethane/urea compositions |
WO2004014969A1 (en) * | 2002-08-09 | 2004-02-19 | Ottawa Health Research Institute | Bio-synthetic matrix and uses thereof |
MXPA05002669A (es) * | 2002-09-13 | 2005-08-19 | Ocular Sciences Inc | Dispositivos y metodos para mejorar la vision. |
EP1583520A4 (de) * | 2003-01-16 | 2007-05-23 | Cornell Res Foundation Inc | Teilweise biologisch abbaubares temperatur- und ph-empfindliches hydrogel |
US8545830B2 (en) * | 2003-03-24 | 2013-10-01 | University Of Tennessee Research Foundation | Multi-functional polymeric materials and their uses |
EP1682161A4 (de) * | 2003-10-29 | 2011-12-07 | Gentis Inc | Polymerisierbare emulsionen für die gewebeherstellung |
US20050119762A1 (en) * | 2003-11-03 | 2005-06-02 | Peter Zilla | Hydrogel providing cell-specific ingrowth |
WO2005085312A1 (en) * | 2004-03-03 | 2005-09-15 | Commonwealth Scientific And Industrial Research Organisation | Biocompatible polymer compositions for dual or multistaged curing |
WO2005095507A1 (en) * | 2004-03-17 | 2005-10-13 | Ciphergen Biosystems, Inc. | Photocrosslinked hydrogel blend surface coatings |
EP1732619A1 (de) | 2004-03-26 | 2006-12-20 | SurModics, Inc. | Zusammensetzung und verfahren zur herstellung von biokompatiblen oberflächen |
GB0407661D0 (en) * | 2004-04-03 | 2004-05-05 | Univ Hull | Liquid crystalline interpenetrating polymer networks |
JP4599550B2 (ja) * | 2004-04-09 | 2010-12-15 | 国立大学法人 東京医科歯科大学 | ナノゲル工学によるハイブリッドゲルの調製とバイオマテリアル応用 |
JP5026956B2 (ja) * | 2004-05-12 | 2012-09-19 | サーモディクス,インコーポレイティド | 医療用具のための天然生分解性多糖コーティング |
US8246993B2 (en) | 2004-06-10 | 2012-08-21 | Cytogel Pharma, Llc | Advantageous hydrogel composition |
US7446131B1 (en) | 2004-06-10 | 2008-11-04 | The United States Of America As Represented By The Secretary Of Agriculture | Porous polymeric matrices made of natural polymers and synthetic polymers and optionally at least one cation and methods of making |
US20060013886A1 (en) | 2004-06-28 | 2006-01-19 | Daqing Wu | Injectable microspheres |
US7235592B2 (en) * | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
WO2006091706A1 (en) * | 2005-02-23 | 2006-08-31 | Zimmer Technology, Inc. | Blend hydrogels and methods of making |
US20060222596A1 (en) | 2005-04-01 | 2006-10-05 | Trivascular, Inc. | Non-degradable, low swelling, water soluble radiopaque hydrogel polymer |
EP1945690B1 (de) * | 2005-09-20 | 2016-07-27 | Polynovo Biomaterials Pty Limited | Kettenverlängerungsmittel |
ATE454908T1 (de) * | 2005-09-21 | 2010-01-15 | Surmodics Inc | In situ okklusionszusammensetzungen mit natürlichen biologisch abbaubaren polysacchariden |
WO2007040557A1 (en) * | 2005-09-21 | 2007-04-12 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
US20070098799A1 (en) * | 2005-10-28 | 2007-05-03 | Zimmer, Inc. | Mineralized Hydrogels and Methods of Making and Using Hydrogels |
AU2006321809A1 (en) * | 2005-12-07 | 2007-06-14 | Zimmer, Inc. | Methods of bonding or modifying hydrogels using irradiation |
US20070141108A1 (en) * | 2005-12-20 | 2007-06-21 | Zimmer, Inc. | Fiber-reinforced water-swellable articles |
US8017107B2 (en) * | 2005-12-22 | 2011-09-13 | Zimmer, Inc. | Perfluorocyclobutane crosslinked hydrogels |
US20070182920A1 (en) * | 2006-02-08 | 2007-08-09 | Coopervision, Inc. | Corneal Onlays and Related Methods |
JP5123285B2 (ja) * | 2006-03-14 | 2013-01-23 | ノボザイムス バイオファーマ デーコー アクティーゼルスカブ | アクリル化ヒアルロン酸 |
US8110242B2 (en) * | 2006-03-24 | 2012-02-07 | Zimmer, Inc. | Methods of preparing hydrogel coatings |
US8795709B2 (en) | 2006-03-29 | 2014-08-05 | Incept Llc | Superabsorbent, freeze dried hydrogels for medical applications |
US20070232762A1 (en) * | 2006-03-31 | 2007-10-04 | Depuy Products, Inc. | Bearing material of medical implant having reduced wear rate and method for reducing wear rate |
US7812098B2 (en) * | 2006-03-31 | 2010-10-12 | Depuy Products, Inc. | Bearing material of medical implant having reduced wear rate and method for reducing wear rate |
US7883520B2 (en) * | 2006-04-10 | 2011-02-08 | Forsight Labs, Llc | Corneal epithelial pocket formation systems, components and methods |
US7872068B2 (en) * | 2006-05-30 | 2011-01-18 | Incept Llc | Materials formable in situ within a medical device |
EP2049591A4 (de) * | 2006-08-02 | 2009-08-19 | Polynovo Biomaterials Pty Ltd | Biokompatible polymerzusammensetzungen |
US20110165236A1 (en) * | 2006-09-22 | 2011-07-07 | Biokey, Inc. | Controlled release hydrogel formulation |
US20080075785A1 (en) * | 2006-09-22 | 2008-03-27 | San-Laung Chow | Controlled release hydrogel formulation |
US20080154241A1 (en) * | 2006-12-07 | 2008-06-26 | Burkstrand Michael J | Latent stabilization of bioactive agents releasable from implantable medical articles |
US9125807B2 (en) | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
US7731988B2 (en) | 2007-08-03 | 2010-06-08 | Zimmer, Inc. | Multi-polymer hydrogels |
US20090043398A1 (en) * | 2007-08-09 | 2009-02-12 | Zimmer, Inc. | Method of producing gradient articles by centrifugation molding or casting |
WO2009029049A1 (en) * | 2007-08-30 | 2009-03-05 | National University Of Singapore | A bone and/or dental cement composition and uses thereof |
US8062739B2 (en) * | 2007-08-31 | 2011-11-22 | Zimmer, Inc. | Hydrogels with gradient |
EP2195361B1 (de) * | 2007-10-03 | 2014-11-26 | Polynovo Biomaterials Limited | Hochmodulige polyurethan- und polyurethan/harnstoff-zusammensetzungen |
US7947784B2 (en) | 2007-11-16 | 2011-05-24 | Zimmer, Inc. | Reactive compounding of hydrogels |
US8034362B2 (en) * | 2008-01-04 | 2011-10-11 | Zimmer, Inc. | Chemical composition of hydrogels for use as articulating surfaces |
CA2719222C (en) | 2008-03-28 | 2018-07-24 | Surmodics, Inc. | Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery |
WO2009137689A2 (en) | 2008-05-07 | 2009-11-12 | Surmodics, Inc. | Delivery of nucleic acid complexes from particles |
US20100087920A1 (en) * | 2008-10-07 | 2010-04-08 | Forsight Labs, Llc | Corneal Onlay Lenses and Related Methods for Improving Vision of Presbyopic Patients |
CN102395401B (zh) | 2009-02-12 | 2015-08-19 | 因赛普特有限责任公司 | 经由水凝胶塞的药物递送 |
CA2977830C (en) | 2009-05-04 | 2019-09-17 | Incept, Llc | Biomaterials for track and puncture closure |
JP2012235797A (ja) | 2009-09-18 | 2012-12-06 | Terumo Corp | ステント |
EP2498764B1 (de) | 2009-11-09 | 2017-09-06 | Spotlight Technology Partners LLC | Fragmentierte hydrogele |
JP5864429B2 (ja) | 2009-11-09 | 2016-02-17 | スポットライト テクノロジー パートナーズ エルエルシーSpotlight Technology Partners Llc | 架橋ヒドロゲル組成物、ヒドロゲル組成物の形成方法、及びキット |
AU2010340067B2 (en) | 2009-12-15 | 2015-03-19 | Incept, Llc | Implants and biodegradable fiducial markers |
EP2574172A4 (de) | 2010-05-21 | 2013-10-30 | Cytogel Pharma Llc | Materialien und verfahren zur behandlung von entzündungen |
US8961501B2 (en) | 2010-09-17 | 2015-02-24 | Incept, Llc | Method for applying flowable hydrogels to a cornea |
US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
SG10201608671SA (en) | 2011-07-18 | 2016-12-29 | Harvard College | Engineered Microbe-Targeting Molecules and Uses Thereof |
US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
RU2521194C2 (ru) * | 2011-11-16 | 2014-06-27 | Общество с ограниченной ответственностью предприятие "Репер" | Матрица для клеточной трансплантологии |
EP3613413A1 (de) | 2011-12-05 | 2020-02-26 | Incept, LLC | Medizinische organogelprozesse und -zusammensetzungen |
EP2978408B1 (de) * | 2013-03-27 | 2019-01-16 | Centre Hospitaller Universitaire Vaudois (CHUV) | Pharmazeutische formulierung zur verwendung bei der behandlung und/oder prävention von restenose |
AU2014268603B2 (en) | 2013-05-21 | 2018-03-22 | President And Fellows Of Harvard College | Engineered heme-binding compositions and uses thereof |
EP3546474B1 (de) | 2013-12-18 | 2021-07-07 | President and Fellows of Harvard College | Crp-erfassung/-detektion von grampositiven bakterien |
US10519443B2 (en) | 2014-09-08 | 2019-12-31 | University Of Iowa Research Foundation | Microrna inhibitor system and methods of use thereof |
US10435457B2 (en) | 2015-08-06 | 2019-10-08 | President And Fellows Of Harvard College | Microbe-binding molecules and uses thereof |
US10273476B2 (en) | 2016-04-30 | 2019-04-30 | University Of Iowa Research Foundation | MicroRNA-200 based approaches for modulating bone formation inhibition and bone regeneration |
MX2019006868A (es) * | 2016-12-16 | 2019-09-23 | Du Pont | Derivados de polisacáridos anfifílicos y composiciones que los comprenden. |
CN106913915B (zh) * | 2017-04-21 | 2019-05-31 | 浙江大学 | 一种自愈合支架复合涂层及其制备方法和应用 |
CN107216450B (zh) * | 2017-04-21 | 2019-06-11 | 浙江大学 | 一种自愈合抗菌涂层及其制备方法和应用 |
US10975121B2 (en) | 2017-06-24 | 2021-04-13 | Cytogel Pharma, Llc | Analgesic mu-opioid receptor binding peptide pharmaceutical formulations and uses thereof |
CN110108537B (zh) * | 2018-02-01 | 2020-08-25 | 中国科学技术大学 | 一种用于生物组织包埋的包埋剂和包埋方法 |
CN108359054A (zh) * | 2018-02-10 | 2018-08-03 | 西北大学 | 一种葡萄糖敏感型全互穿网络水凝胶及其制备方法 |
CN116496475B (zh) * | 2023-06-26 | 2023-09-22 | 海杰亚(北京)医疗器械有限公司 | 用于栓塞微球的可降解交联剂、可降解栓塞微球及其制备方法和药物组合物 |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4002173A (en) | 1974-07-23 | 1977-01-11 | International Paper Company | Diester crosslinked polyglucan hydrogels and reticulated sponges thereof |
US4032488A (en) * | 1975-10-03 | 1977-06-28 | Meito Sangyo Kabushiki Kaisha | Dextran ester-olefin compound copolymer and process for preparing same |
SU729197A1 (ru) * | 1977-07-05 | 1980-04-25 | Ордена Ленина Институт Элементоорганических Соединений Ан Ссср | Сшитые сополимеры хитозана |
US4277582A (en) * | 1978-03-03 | 1981-07-07 | Ciba-Geigy Corporation | Water-insoluble hydrophilic copolymers |
GB8418772D0 (en) | 1984-07-24 | 1984-08-30 | Geistlich Soehne Ag | Chemical substances |
US4857602A (en) * | 1986-09-05 | 1989-08-15 | American Cyanamid Company | Bioabsorbable surgical suture coating |
US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5626863A (en) | 1992-02-28 | 1997-05-06 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
US5529914A (en) * | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
US5410016A (en) * | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
US5210111A (en) * | 1991-08-22 | 1993-05-11 | Ciba-Geigy Corporation | Crosslinked hydrogels derived from hydrophilic polymer backbones |
EP0610441A4 (de) | 1991-10-29 | 1996-01-10 | Clover Cons Ltd | Vernetzbare polysacchariden, polykationen und lipiden verwendbar zum einkapseln und abgabe von arzneimitteln. |
DE69328523T2 (de) * | 1992-02-13 | 2000-09-21 | Surmodics Inc | Immobilisierung eines chemischen spezies in einer vernetzten matrix |
US5573934A (en) | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
EP0627911B1 (de) | 1992-02-28 | 2000-10-25 | Board Of Regents The University Of Texas System | Photopolymerinierbare, biologisch abbaubare hydrogele als gewebekontaktmaterialien und trägerstoffe für kontrollierte freisetzung |
IT1260154B (it) | 1992-07-03 | 1996-03-28 | Lanfranco Callegaro | Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn) |
US5514379A (en) | 1992-08-07 | 1996-05-07 | The General Hospital Corporation | Hydrogel compositions and methods of use |
ATE151778T1 (de) | 1992-11-30 | 1997-05-15 | Ciba Geigy Ag | Polymerisierbare kohlenhydratester, polymere daraus und deren verwendung |
KR0141431B1 (ko) | 1994-05-17 | 1998-07-01 | 김상웅 | 생분해성 하이드로겔 고분자 |
TW291481B (en) * | 1994-10-27 | 1996-11-21 | Novartis Erfind Verwalt Gmbh | Poly-unsaturated carbohydrate derivatives, polymers thereof and their use |
US5607686A (en) | 1994-11-22 | 1997-03-04 | United States Surgical Corporation | Polymeric composition |
US5540929A (en) | 1995-03-08 | 1996-07-30 | Board Of Trustees Operating Michigan State University | Polysaccharides grafted with aliphatic polyesters derived from cyclic esters |
US5900245A (en) * | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
CA2228118A1 (en) * | 1995-07-28 | 1997-02-13 | Focal, Inc. | Multiblock biodegradable hydrogels for use as controlled release agents for drugs delivery and tissue treatments agents |
JP3572144B2 (ja) * | 1996-05-31 | 2004-09-29 | 名糖産業株式会社 | デキストランエステル共重合体 |
US5854382A (en) * | 1997-08-18 | 1998-12-29 | Meadox Medicals, Inc. | Bioresorbable compositions for implantable prostheses |
JP4330268B2 (ja) * | 1997-09-03 | 2009-09-16 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 新規な生体模倣ヒドロゲル材料 |
AU5571399A (en) * | 1998-08-31 | 2000-03-21 | Cornell Research Foundation Inc. | Dextran-maleic acid monoesters and hydrogels based thereon |
WO2000060956A1 (en) | 1999-04-12 | 2000-10-19 | Cornell Research Foundation, Inc. | Hydrogel-forming system with hydrophobic and hydrophilic components |
US6716445B2 (en) | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
WO2001015627A1 (en) * | 1999-09-02 | 2001-03-08 | Alcon Universal Ltd. | Hydrophobically-bound, hydrophilic coating compositions for surgical implants |
US6503538B1 (en) | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
US6592895B2 (en) | 2001-08-02 | 2003-07-15 | Cornell Research Foundation, Inc. | Biodegradable polyhydric alcohol esters |
-
2000
- 2000-03-20 WO PCT/US2000/006416 patent/WO2000060956A1/en active IP Right Grant
- 2000-03-20 DE DE60038010T patent/DE60038010T2/de not_active Expired - Lifetime
- 2000-03-20 DK DK00917865T patent/DK1168934T3/da active
- 2000-03-20 AU AU38772/00A patent/AU3877200A/en not_active Abandoned
- 2000-03-20 JP JP2000610306A patent/JP4558213B2/ja not_active Expired - Fee Related
- 2000-03-20 ES ES00917865T patent/ES2298135T3/es not_active Expired - Lifetime
- 2000-03-20 EP EP00917865A patent/EP1168934B1/de not_active Expired - Lifetime
- 2000-03-20 CA CA2368617A patent/CA2368617C/en not_active Expired - Fee Related
- 2000-03-20 AT AT00917865T patent/ATE386075T1/de not_active IP Right Cessation
- 2000-03-20 US US09/531,451 patent/US6388047B1/en not_active Expired - Lifetime
-
2002
- 2002-03-13 US US10/096,435 patent/US6583219B2/en not_active Expired - Fee Related
-
2003
- 2003-02-21 US US10/369,676 patent/US6709668B2/en not_active Expired - Fee Related
- 2003-12-12 US US10/733,291 patent/US6916857B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20020161169A1 (en) | 2002-10-31 |
US20030125509A1 (en) | 2003-07-03 |
US6583219B2 (en) | 2003-06-24 |
DE60038010D1 (de) | 2008-03-27 |
WO2000060956A1 (en) | 2000-10-19 |
JP4558213B2 (ja) | 2010-10-06 |
AU3877200A (en) | 2000-11-14 |
US6709668B2 (en) | 2004-03-23 |
JP2002541308A (ja) | 2002-12-03 |
EP1168934A1 (de) | 2002-01-09 |
CA2368617C (en) | 2010-03-16 |
US20040122165A1 (en) | 2004-06-24 |
EP1168934B1 (de) | 2008-02-13 |
CA2368617A1 (en) | 2000-10-19 |
US6388047B1 (en) | 2002-05-14 |
ES2298135T3 (es) | 2008-05-16 |
US6916857B2 (en) | 2005-07-12 |
EP1168934A4 (de) | 2004-12-08 |
ATE386075T1 (de) | 2008-03-15 |
DE60038010T2 (de) | 2009-03-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1168934T3 (da) | Hydrogeldannende system med hydrofobe og hydrofile komponenter | |
DE69721265D1 (de) | Hydrolysierbare hydrogele zur gesteuerten freisetzung | |
FI103381B1 (fi) | Hyaluronihapon veteen liukenemattomia geelejä ja menetelmä sen valmistamiseksi | |
US7049351B2 (en) | Moldings and preparation and uses thereof | |
AU5469990A (en) | Water soluble high molecular polymerized drug preparation | |
AU590565B2 (en) | Controlled release delivery system for macromolecules | |
DE3751647D1 (de) | Biologisch abbaubare Mikrokugeln als Träger für Makromoleküle | |
MX193604B (es) | Hidrogeles hidrofilicos altamente hinchables | |
WO2002087001A3 (en) | Polymer electrolyte membrane | |
BR9206222A (pt) | Catalisador de ácido de lewis imobilizado de preparação de um catalisador imobilizado moldado, processo para polimerizar monômero cationicamente polimerizável, composição e polímero cationicamente polimerizado. | |
CA2336138A1 (en) | Polymers for delivering nitric oxide in vivo | |
TW200502011A (en) | Superabsorbent polymer with high permeability | |
BR0010083A (pt) | Processo de preparação de poliolefinas, poliolefinas comportando grupos ácidos parcialmente neutralizados, utilização de poliolefinas, e, processo de extrusão em espuma | |
DE59504351D1 (de) | Implantierbare formkörper zur verabreichung von wirkstoffen an pflanzen | |
ATE410473T1 (de) | Polymerstrukturen mit einem hydrophil/lipophil- system | |
ZA957471B (en) | Contrast agents | |
MXPA02009064A (es) | Pelicula superabsorbente a base de polisacarido.. | |
WO2005065712A3 (en) | Complexes having adjuvant activity | |
EP1106189A3 (de) | Lichthärtender Gewebeklebstoff | |
BR0014638A (pt) | Composição polimérica superabsorvente, artigo absorvente, e processo para preparar um artigo absorvente | |
AU8085691A (en) | Activation of polysaccharide hydrolase | |
EP0331052A3 (de) | Verfahren zur Imidierung von Acrylpolymeren | |
ES481386A1 (es) | Procedimiento de preparacion de polimeros hidrosolubles. | |
ES481385A1 (es) | Procedimiento de preparacion de polimeros organicos. | |
EP1077200A3 (de) | Aus wasserlöslichen radikalpolymerisierbaren Monomeren erhaltenes Polymer, dessen Verfahren zur Herstellung und dies enthaltendes Flockungsmittel |