DK1137670T3 - Fremgangsmåde til tværbinding af carboxylerede polysaccharider - Google Patents

Fremgangsmåde til tværbinding af carboxylerede polysaccharider

Info

Publication number
DK1137670T3
DK1137670T3 DK99971819T DK99971819T DK1137670T3 DK 1137670 T3 DK1137670 T3 DK 1137670T3 DK 99971819 T DK99971819 T DK 99971819T DK 99971819 T DK99971819 T DK 99971819T DK 1137670 T3 DK1137670 T3 DK 1137670T3
Authority
DK
Denmark
Prior art keywords
carboxylated polysaccharides
crosslinking carboxylated
cross
crosslinking
polysaccharide
Prior art date
Application number
DK99971819T
Other languages
Danish (da)
English (en)
Inventor
Rolando Barbucci
Giancarlo Sportoletti
Original Assignee
Farmila Thea Farmaceutici S P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11381036&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1137670(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Farmila Thea Farmaceutici S P filed Critical Farmila Thea Farmaceutici S P
Application granted granted Critical
Publication of DK1137670T3 publication Critical patent/DK1137670T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/005—Crosslinking of cellulose derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/003—Crosslinking of starch
    • C08B31/006—Crosslinking of derivatives of starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
DK99971819T 1998-11-11 1999-11-09 Fremgangsmåde til tværbinding af carboxylerede polysaccharider DK1137670T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1998MI002443A IT1303738B1 (it) 1998-11-11 1998-11-11 Processo di reticolazione di polisaccaridi carbossilati.
PCT/EP1999/008480 WO2000027886A1 (en) 1998-11-11 1999-11-09 Cross-linking process of carboxylated polysaccharides
EP99971819A EP1137670B1 (en) 1998-11-11 1999-11-09 Cross-linking process of carboxylated polysaccharides

Publications (1)

Publication Number Publication Date
DK1137670T3 true DK1137670T3 (da) 2005-07-25

Family

ID=11381036

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99971819T DK1137670T3 (da) 1998-11-11 1999-11-09 Fremgangsmåde til tværbinding af carboxylerede polysaccharider

Country Status (25)

Country Link
US (2) US6734298B1 (zh)
EP (1) EP1137670B1 (zh)
JP (1) JP2002529549A (zh)
KR (1) KR100685454B1 (zh)
CN (1) CN1144818C (zh)
AT (1) ATE291590T1 (zh)
AU (1) AU756158B2 (zh)
BR (1) BR9915238A (zh)
CA (1) CA2350665A1 (zh)
CZ (1) CZ303485B6 (zh)
DE (1) DE69924407T2 (zh)
DK (1) DK1137670T3 (zh)
ES (1) ES2237971T3 (zh)
HK (1) HK1041010B (zh)
HU (1) HU227731B1 (zh)
IL (1) IL143064A0 (zh)
IT (1) IT1303738B1 (zh)
NO (1) NO20012316L (zh)
NZ (1) NZ511308A (zh)
PT (1) PT1137670E (zh)
RU (1) RU2230073C2 (zh)
SI (1) SI1137670T1 (zh)
TR (1) TR200101325T2 (zh)
WO (1) WO2000027886A1 (zh)
ZA (1) ZA200103800B (zh)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD980037A1 (it) * 1998-02-25 1999-08-25 Fidia Advanced Biopolymers Srl Acido ialuronico solfatato e i suoi derivati legati covalentemente a polimeri sintetici pe la preparazione di biomateriali e per il rivesti
IT1303738B1 (it) 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
IT1303735B1 (it) * 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S Acidi ialuronici reticolati e loro usi medici.
FR2799196B1 (fr) * 1999-10-04 2002-02-08 Sod Conseils Rech Applic Copolymeres reticules a base de copolymeres polycarboxyliques non reticules
KR100375299B1 (ko) * 2000-10-10 2003-03-10 주식회사 엘지생명과학 히알루론산의 가교결합형 아마이드 유도체와 이의 제조방법
US6500947B1 (en) 2001-08-24 2002-12-31 Weyerhaeuser Company Superabsorbent polymer
KR100493461B1 (ko) * 2002-02-27 2005-06-07 재단법인서울대학교산학협력재단 접착분자가 부착된 천연고분자, 그의 제조방법 및 그의 용도
FR2839312A1 (fr) * 2002-05-03 2003-11-07 Roquette Freres Procede de transformation de matieres amylacees par traitement thermique, en l'absence de solvant, en phase ou semi-seche
KR20040009891A (ko) * 2002-07-26 2004-01-31 주식회사 엘지생명과학 히알루론산의 유도체 겔 및 그 제조방법
KR100523953B1 (ko) * 2002-08-27 2005-10-25 주식회사 엘지생명과학 천연다당류와 히알루론산의 마이크로비드 및 이의 제조 방법
DE10256558A1 (de) * 2002-12-04 2004-09-16 Supramol Parenteral Colloids Gmbh Ester von Polysaccharid Aldonsäuren, Verfahren zu ihrer Herstellung und Verwendung zur Kopplung an pharmazeutische Wirkstoffe
US7485719B2 (en) 2003-02-21 2009-02-03 Terumo Kabushiki Kaisha Crosslinkable polysaccharide derivative, process for producing the same, crosslinkable polysaccharide composition, and medical treatment material
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
JP4669919B2 (ja) * 2003-06-06 2011-04-13 コスモテック株式会社 医療用組成物
JP2007526941A (ja) 2004-02-23 2007-09-20 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー バイオマス由来材料を含有する架橋ポリマー
WO2005087289A1 (ja) * 2004-03-15 2005-09-22 Terumo Kabushiki Kaisha 癒着防止材
EP1769004B1 (de) * 2004-06-21 2017-08-09 Evonik Degussa GmbH Wasserabsorbierendes polysaccharid sowie ein verfahren zu seiner herstellung
ITMI20041373A1 (it) 2004-07-09 2004-10-09 Lima Lto S P A N-metil-ammidi di carbossimetilcellulosa acido alginico o carbossimetalamido
US7541396B2 (en) 2004-12-29 2009-06-02 Weyerhaeuser Nr Company Method for making carboxyalkyl cellulose
US7393905B2 (en) * 2004-12-29 2008-07-01 Weyerhaeuser Company Crosslinked mixed carboxylated polymer network
US7230049B2 (en) * 2004-12-29 2007-06-12 Weyerhaeuser Co. Method of crosslinking a carboxylated polymer using a triazine crosslinking activator
US7241836B2 (en) * 2004-12-29 2007-07-10 Weyerhaeuser Co. Method of crosslinking a mixture of carboxylated polymers using a triazine crosslinking activator
US20060142476A1 (en) * 2004-12-29 2006-06-29 Weerawarna S A Crosslinked carboxylated polymer
US7300965B2 (en) 2004-12-29 2007-11-27 Weyerhaeuser Company Mixed polymer network
RU2472809C2 (ru) * 2005-09-02 2013-01-20 Колбар Лайфсайенс Лтд. Поперечно сшитые полисахаридные и белковые матрицы и способы их получения
AU2007329435B2 (en) * 2006-12-04 2013-06-06 Johns Hopkins University Imidated biopolymer adhesive and hydrogel
KR100825519B1 (ko) 2007-01-05 2008-04-25 주식회사 바이오폴리메드 키토산 기재 고분자 접합체 및 그 제조방법
US20080293637A1 (en) * 2007-05-23 2008-11-27 Allergan, Inc. Cross-linked collagen and uses thereof
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
SI2818184T1 (sl) 2007-11-16 2019-03-29 Aclaris Therapeutics, Inc. Sestava in postopki za zdravljenje purpure
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP3184552B1 (en) 2008-09-02 2020-08-12 Tautona Group LP Threads of hyaluronic acid, methods of making thereof and uses thereof
US8361926B2 (en) 2008-11-25 2013-01-29 Evonik Stockhausen, Llc Water-absorbing polysaccharide and method for producing the same
DK2413894T3 (en) * 2009-04-02 2017-04-03 Allergan Inc HIGHLY FORMED HYDROGLES FOR SOFTWARE STRENGTH
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
JP5749283B2 (ja) 2010-03-12 2015-07-15 アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエＡｌｌｅｒｇａｎ Ｉｎｄｕｓｔｒｉｅ Ｓａｓ 皮膚状態を改善するための流体組成物
DK3078388T3 (da) 2010-03-22 2019-05-20 Allergan Inc Tværbundne hydrogeler til blødvævsforøgelse
EP2600858A4 (en) * 2010-08-04 2014-03-05 Tixupharma SUPRAMOLECULAR COMPLEXES OF POLYANIONIC POLYMERS AND SPERMIDINE FOR WOVEN CARE AND REPAIR
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
CN107412002A (zh) 2011-06-03 2017-12-01 阿勒根公司 包括抗氧化剂的皮肤填充剂组合物
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
CN103113495A (zh) * 2013-02-03 2013-05-22 江苏天竹化工科技有限公司 一种可光聚合透明质酸衍生物及其制备方法
ITUD20130119A1 (it) * 2013-09-12 2015-03-13 Limacorporate Spa Idrogel biocompatibile per uso biomedico o farmaceutico, polimero intermedio per realizzare detto idrogel biocompatibile e relativo metodo di realizzazione
ES2811269T3 (es) 2014-01-31 2021-03-11 Seikagaku Kogyo Co Ltd Agente de reticulación de diamina, cuerpo reticulado de polisacárido ácido y material médico
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
JP6110037B2 (ja) 2015-01-16 2017-04-05 生化学工業株式会社 コンドロイチン硫酸架橋体、並びにこれを含有する組成物、及び眼疾患処置剤
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
CN107207627B (zh) 2015-02-27 2022-05-24 学校法人常翔学园 具有膜透过性肽链的多糖衍生物
US20180086852A1 (en) * 2015-03-31 2018-03-29 Kewpie Corporation Hyaluronic Acid Derivative and Manufacturing Method Therefor and Cosmetics, Food Composition, and Pharmaceutical Composition Containing Hyaluronic Acid Derivative
CZ306479B6 (cs) * 2015-06-15 2017-02-08 Contipro A.S. Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
GB201511218D0 (en) 2015-06-25 2015-08-12 Goe Ip As Reservoir treatments
CN105566511B (zh) * 2016-01-27 2017-11-03 天津医科大学 电荷翻转普鲁兰多糖衍生物及其合成方法和用途
CN110961057A (zh) * 2020-01-16 2020-04-07 江苏罗格斯生物科技有限公司 一种绿色生物水凝胶输送系统及其制备方法
RU2743941C1 (ru) * 2020-07-29 2021-03-01 Федеральное государственное бюджетное учреждение науки Институт химии Дальневосточного отделения Российской академии наук (ИХ ДВО РАН) Способ получения биополимерного гидрогеля
CN114230678B (zh) * 2021-12-13 2023-09-01 珠海通桥医疗科技有限公司 一种用于血管内治疗的光交联水凝胶栓塞系统及使用方法
CN114507359A (zh) * 2022-02-17 2022-05-17 浙江大学 木质素磺酸盐的改性材料制备法及其在纳米农药中的应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5257102A (en) * 1975-11-06 1977-05-11 Sumitomo Chemical Co Process for preparing carboxylic acid amide
US4716224A (en) * 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
SE442820B (sv) * 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
US4636524A (en) * 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
SE8501022L (sv) * 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
US4713448A (en) * 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
IT1184161B (it) * 1985-03-14 1987-10-22 Franco Conti Derivati del chitosano costituiti da complessi di coordinazione con ioni ferrosi
IT1198449B (it) * 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
SK278783B6 (sk) * 1989-12-18 1998-02-04 Chemický Ústav Sav Spôsob naviazania biologicky aktívnych látok obsah
DE527942T1 (de) * 1990-05-04 1994-03-03 Perio Prod Ltd System zur arzneistoffabgabe im colon.
ES2149178T3 (es) * 1991-08-16 2000-11-01 Miles A Galin Implante ocular para la camara anterior refractivo, recubierto con un medicamento.
JP2855307B2 (ja) * 1992-02-05 1999-02-10 生化学工業株式会社 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法
CA2076732C (en) * 1992-04-17 2006-05-09 Kimberly-Clark Worldwide, Inc. Modified polysaccharides having improved absorbent properties and process for the preparation thereof
US5550189A (en) * 1992-04-17 1996-08-27 Kimberly-Clark Corporation Modified polysaccharides having improved absorbent properties and process for the preparation thereof
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
JP3107726B2 (ja) * 1994-05-13 2000-11-13 株式会社クラレ 水膨潤性高分子ゲル
US5690961A (en) * 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses
JP4018181B2 (ja) * 1995-11-07 2007-12-05 生化学工業株式会社 グリコサミノグリカン誘導体およびその製造法
JPH09176204A (ja) * 1995-12-28 1997-07-08 Kazukiyo Kobayashi シアロ糖鎖含有機能性物質及びその合成方法
JPH09278803A (ja) * 1996-04-09 1997-10-28 Kuraray Co Ltd 医療用手当材
JP3413062B2 (ja) * 1996-06-19 2003-06-03 キヤノン株式会社 糖鎖高分子化合物を含む高分子化合物及びその分解方法
FR2752843B1 (fr) * 1996-08-30 1998-10-16 Sod Conseils Rech Applic Copolymeres reticules a base de polymeres polycarboxyliques et leur utilisation comme support de composition pharmaceutique
US6642363B1 (en) * 1996-09-19 2003-11-04 The Regents Of The University Of Michigan Polymers containing polysaccharides such as alginates or modified alginates
US6630457B1 (en) * 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
IT1303738B1 (it) 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
IT1303735B1 (it) * 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S Acidi ialuronici reticolati e loro usi medici.

Also Published As

Publication number Publication date
ES2237971T3 (es) 2005-08-01
IL143064A0 (en) 2002-04-21
HU227731B1 (en) 2012-01-30
HUP0104075A3 (en) 2003-03-28
AU1380300A (en) 2000-05-29
CN1144818C (zh) 2004-04-07
AU756158B2 (en) 2003-01-02
ZA200103800B (en) 2002-06-10
RU2230073C2 (ru) 2004-06-10
HK1041010B (zh) 2004-10-08
JP2002529549A (ja) 2002-09-10
PT1137670E (pt) 2005-06-30
EP1137670A1 (en) 2001-10-04
US6734298B1 (en) 2004-05-11
DE69924407D1 (de) 2005-04-28
TR200101325T2 (tr) 2001-10-22
IT1303738B1 (it) 2001-02-23
KR20010101002A (ko) 2001-11-14
SI1137670T1 (en) 2005-06-30
HK1041010A1 (en) 2002-06-28
CZ303485B6 (cs) 2012-10-17
NO20012316D0 (no) 2001-05-10
BR9915238A (pt) 2001-07-24
EP1137670B1 (en) 2005-03-23
CZ20011651A3 (cs) 2001-12-12
US20040167098A1 (en) 2004-08-26
WO2000027886A1 (en) 2000-05-18
DE69924407T2 (de) 2005-08-11
HUP0104075A2 (hu) 2002-04-29
KR100685454B1 (ko) 2007-02-23
CN1325409A (zh) 2001-12-05
ITMI982443A1 (it) 2000-05-11
NZ511308A (en) 2003-06-30
ATE291590T1 (de) 2005-04-15
CA2350665A1 (en) 2000-05-18
NO20012316L (no) 2001-07-06

Similar Documents

Publication Publication Date Title
DK1137670T3 (da) Fremgangsmåde til tværbinding af carboxylerede polysaccharider
ES2155427T1 (es) Sistema de osteosintesis raquidea con medios de apriete, en particular de fijacion anterior.
YU46598A (sh) Jonski konjugat zadržanog oslobađanja
DK1144459T3 (da) Tværbundne hyaluronsyrer og medicinske anvendelser deraf
ATE236622T1 (de) Blockcopolymere
DE60014604D1 (de) Klebstoffe
NO20002785D0 (no) Adamantanderivater
NO20002786L (no) Adamantanderivater
HUP9902027A2 (hu) Beültethető akrilamid kopolimer hidrogél terápiás használatra
ATE335011T1 (de) Verfahren zur vernetzung von hyaluronsäure mit polymeren
ATE213005T1 (de) Kontinuierliches polymerisationverfahren von polyamiden
FR2811540B1 (fr) Implant intervertebral amortissant
MXPA02012601A (es) Polimeros radicales cationicos o anfotericos autoadhesivos y su uso en cosmeticos.
PL331848A1 (en) Crosslinked copolymers on the basis of polycarboxylic polymers
DK0994732T3 (da) Absorberende struktur omfattende en stærkt absorberende polymer og en absorberende artikel omfattende den absorberende struktur
ATE542571T1 (de) Kosmetische zubereitungen, die amphoterische urethanharze und silikonpolymere enthalten
DK1037642T3 (da) Modificerede polysaccharider med ændret biologisk genkendelse
DK1143917T3 (da) Antikonvulsive derivater egnet til behandling af posttraumatisk stresssygdom
DK1141069T3 (da) Coatingsammensætning
ITTO940892A0 (it) Polimero anionico, ad esempio di tipo superassorbente e relativo procedimento di produzione.