HUP9902027A2 - Beültethető akrilamid kopolimer hidrogél terápiás használatra - Google Patents

Beültethető akrilamid kopolimer hidrogél terápiás használatra

Info

Publication number
HUP9902027A2
HUP9902027A2 HU9902027A HUP9902027A HUP9902027A2 HU P9902027 A2 HUP9902027 A2 HU P9902027A2 HU 9902027 A HU9902027 A HU 9902027A HU P9902027 A HUP9902027 A HU P9902027A HU P9902027 A2 HUP9902027 A2 HU P9902027A2
Authority
HU
Hungary
Prior art keywords
polymer
implantable
stone
therapeutic uses
acrylamide copolymer
Prior art date
Application number
HU9902027A
Other languages
English (en)
Inventor
Stéphane Woerly
Original Assignee
Organogel Canada Ltee.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organogel Canada Ltee. filed Critical Organogel Canada Ltee.
Publication of HUP9902027A2 publication Critical patent/HUP9902027A2/hu
Publication of HUP9902027A3 publication Critical patent/HUP9902027A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3878—Nerve tissue, brain, spinal cord, nerves, dura mater
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A hidrőgél egy N-szűbtitűált metakrilamid vagy akrilamid, egykeresztkötő ágens és egy kőmplex cűkőr vagy ennek származéka, egyszövetadhéziós peptid vagy egy antitestekkel készült pőlimerkőnjűgátűm kőpőlimerje, mely pőlimer heterőgén, elasztikűsandefőrmálható és legalább körülbelül 80%-ős egyensúlyi víztartalőmmalrendelkezik. Felhasználható szöveti regenerációhőz és szervkijavításáhőz, példáűl a fejlődő és felnőtt idegrendszerben. ŕ
HU9902027A 1996-10-16 1997-10-15 Implantable acrylamide copolymer hydrogel for therapeutic uses HUP9902027A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/731,484 US5863551A (en) 1996-10-16 1996-10-16 Implantable polymer hydrogel for therapeutic uses

Publications (2)

Publication Number Publication Date
HUP9902027A2 true HUP9902027A2 (hu) 1999-10-28
HUP9902027A3 HUP9902027A3 (en) 2001-04-28

Family

ID=24939700

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9902027A HUP9902027A3 (en) 1996-10-16 1997-10-15 Implantable acrylamide copolymer hydrogel for therapeutic uses

Country Status (18)

Country Link
US (1) US5863551A (hu)
EP (1) EP0929323B1 (hu)
JP (1) JP3542810B2 (hu)
KR (1) KR100377520B1 (hu)
CN (1) CN1211194A (hu)
AT (1) ATE284717T1 (hu)
AU (1) AU744666B2 (hu)
BR (1) BR9706835A (hu)
CA (1) CA2240721C (hu)
CZ (1) CZ187698A3 (hu)
DE (1) DE69731959T2 (hu)
HU (1) HUP9902027A3 (hu)
IL (1) IL124894A (hu)
NZ (1) NZ330664A (hu)
PL (1) PL327454A1 (hu)
RU (1) RU2198686C2 (hu)
SK (1) SK79698A3 (hu)
WO (1) WO1998016266A1 (hu)

Families Citing this family (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4335316B2 (ja) * 1996-09-19 2009-09-30 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン アルギネートまたは修飾アルギネートのようなポリサッカライドを含むポリマー
US8003705B2 (en) * 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
US20030008396A1 (en) * 1999-03-17 2003-01-09 Ku David N. Poly(vinyl alcohol) hydrogel
EP1079749A1 (en) 1998-05-23 2001-03-07 Focal, Inc. Method of treatment for premature rupture of membranes in pregnancy (prom)
US6165193A (en) 1998-07-06 2000-12-26 Microvention, Inc. Vascular embolization with an expansible implant
US6117293A (en) * 1998-07-31 2000-09-12 Biowhittaker Molecular Applications, Inc. Method for producing hydrophilic monomers and uses thereof
US6464850B1 (en) * 1998-07-31 2002-10-15 Biowhittaker Molecular Applications, Inc. Method for producing hydrophilic monomers and uses thereof
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
AU2707500A (en) * 1998-12-04 2000-06-26 Incept Llc Biocompatible crosslinked polymers
JP2002542326A (ja) * 1999-04-09 2002-12-10 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン 多孔性ハイドロゲル製品の製造
US6264695B1 (en) * 1999-09-30 2001-07-24 Replication Medical, Inc. Spinal nucleus implant
JP2003520209A (ja) * 1999-12-16 2003-07-02 トライデント テクノロジーズ リミテッド ライアビリティ カンパニー 受容体負荷投与量を含む治療剤の長期送達システム及び方法
US6664305B2 (en) 2000-06-27 2003-12-16 Bia Separations D.O.O. Chromatography material and a process of manufacturing that material
US6638312B2 (en) * 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) * 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
DE60133494T2 (de) 2000-08-30 2009-04-30 Warsaw Orthopedic, Inc., Warsaw Bandscheibenkern-Implantate
US7204851B2 (en) * 2000-08-30 2007-04-17 Sdgi Holdings, Inc. Method and apparatus for delivering an intervertebral disc implant
US7503936B2 (en) * 2000-08-30 2009-03-17 Warsaw Orthopedic, Inc. Methods for forming and retaining intervertebral disc implants
US20020026244A1 (en) * 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US6878384B2 (en) 2001-03-13 2005-04-12 Microvention, Inc. Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use
KR100444944B1 (ko) * 2001-05-24 2004-08-18 선바이오(주) 생체 접착제용 폴리에틸렌글리콜 수화젤
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
JP2005515802A (ja) 2001-07-16 2005-06-02 デピュイ・プロダクツ・インコーポレイテッド 混成生物／合成品型多孔質細胞外基質支持骨格
EP1416886A4 (en) * 2001-07-16 2007-04-18 Depuy Products Inc SCAFFOLD AND METHOD FOR CARTILAGE REPAIR AND REGENERATION
EP1416866A4 (en) * 2001-07-16 2007-04-18 Depuy Products Inc DEVICES FROM NATURALLY OBTAINING MEANS OF BIOLOGICAL ORIGIN
AU2002354913B2 (en) * 2001-07-16 2008-07-17 Depuy Products, Inc. Unitary surgical device and method
US7201917B2 (en) 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
AU2002354911B2 (en) * 2001-07-16 2007-08-30 Depuy Products, Inc. Meniscus regeneration device and method
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
DK1438976T3 (da) * 2001-09-28 2008-04-28 Biopharma Dev Ltd Polyfunktionel biokompatibel hydrogel og fremgangsmåde til fremstilling deraf
US20040047843A1 (en) * 2002-02-12 2004-03-11 Uab Research Foundation Method for spinal cord reconnection
AU2003216379A1 (en) * 2002-02-22 2003-09-09 Control Delivery Systems, Inc. Method for treating otic disorders
US20060015083A1 (en) * 2002-03-11 2006-01-19 Munro Hugh S Absorbent hydrogels
NZ536201A (en) * 2002-04-10 2005-08-26 Obschestvo S Ogranichennoi Otv Polyfunctional biocompatible hydrogel and method for the production thereof
KR100518152B1 (ko) * 2002-05-09 2005-09-29 메디제네스(주) 혈장 또는 혈청을 함유한 창상 치료용 약학 조성물
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
US20060034807A1 (en) * 2002-08-09 2006-02-16 Ottawa Health Research Institute Innervated artificial tissues and uses thereof
US7569222B2 (en) * 2002-11-18 2009-08-04 Woerly Stephane Hydrogel membrane composition and use thereof
CA2509634C (en) * 2002-12-18 2011-11-22 The Regents Of The University Of California Biocompatible hydrogel bone-like composites
WO2004071336A2 (en) * 2003-02-06 2004-08-26 The General Hospital Corporation D/B/A Massachusetts General Hospital Hydrophilic fibrous capsule resistant prosthetic device
US7785769B2 (en) * 2003-07-25 2010-08-31 The United States of America as reprsented by the Secretary of the Navy Immobilization of oligonucleotides and proteins in sugar-containing hydrogels
CA2558661C (en) 2004-02-06 2012-09-04 Georgia Tech Research Corporation Load bearing biocompatible device
CA2558623C (en) * 2004-02-06 2013-04-16 Georgia Tech Research Corporation Surface directed cellular attachment
US7569233B2 (en) * 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US20050249772A1 (en) * 2004-05-04 2005-11-10 Prasanna Malaviya Hybrid biologic-synthetic bioabsorbable scaffolds
US20050278025A1 (en) * 2004-06-10 2005-12-15 Salumedica Llc Meniscus prosthesis
US7303074B2 (en) * 2004-09-22 2007-12-04 Dombrowski Trudy M Foldable organizer device
US20070142326A1 (en) * 2004-09-30 2007-06-21 Youe-Kong Shue Treatment of a condition in a mammal with administration of aminosugar and uses thereof
US20060089719A1 (en) * 2004-10-21 2006-04-27 Trieu Hai H In situ formation of intervertebral disc implants
US7513866B2 (en) * 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7313829B1 (en) * 2004-10-29 2008-01-01 Payload Systems, Inc. Sealing device for body suit and sealing method using hydrogels
RU2290939C2 (ru) * 2004-12-14 2007-01-10 Государственное образовательное учреждение высшего профессионального образования Новосибирская государственная медицинская академия Министерства здравоохранения Российской Федерации Средство для лечения повреждений спинного и головного мозга
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
AU2006282883A1 (en) * 2005-08-26 2007-03-01 Synthes Gmbh Hydrogel balloon prosthesis for nucleus pulposus
WO2007043973A1 (en) * 2005-10-13 2007-04-19 Dso National Laboratories Method of enhancing a fluorescent signal
WO2007070660A2 (en) 2005-12-13 2007-06-21 President And Fellows Of Harvard College Scaffolds for cell transplantation
PT1991601E (pt) * 2006-03-03 2010-11-29 Akzo Nobel Nv Processo para a modificação de polímeros biodegradáveis
US8377091B2 (en) 2006-06-15 2013-02-19 Microvention, Inc. Embolization device constructed from expansile polymer
US8066750B2 (en) 2006-10-06 2011-11-29 Warsaw Orthopedic, Inc Port structures for non-rigid bone plates
US7871440B2 (en) * 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
WO2008130263A1 (fr) * 2007-04-20 2008-10-30 Institut Molekulyarnoi Biologii Im V.A. Engeldardta Rossiskoi Akademii Nauk Monomère et composition destinés à la réception d'hydrogel à faible pourcentage et/ou de l'hydrogel possédant une faible quantité de réticulations transversales, hydrogel et la biopuce basés sur cet hydrogel
WO2008130068A1 (en) * 2007-04-23 2008-10-30 Modern Cell & Tissue Technologies Inc. Method for preparing a porous polymer scaffold using dry ice
US8067028B2 (en) * 2007-08-13 2011-11-29 Confluent Surgical Inc. Drug delivery device
AU2008345590B2 (en) 2007-12-21 2014-10-30 Microvention, Inc. Hydrogel filaments for biomedical uses
WO2009102465A2 (en) 2008-02-13 2009-08-20 President And Fellows Of Harvard College Continuous cell programming devices
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
EP2293775A2 (en) 2008-05-29 2011-03-16 Politecnico di Milano Hydrogel capable of containing and conveying cells
WO2010062734A1 (en) * 2008-11-03 2010-06-03 University Of Maryland, Baltimore Blood coagulation inducing polymer hydrogel
FR2942408B1 (fr) 2009-02-24 2012-01-27 Stephane Woerly Hydrogel heterogene hybride et son utilisation therapeutique
EP2424775B1 (en) 2009-04-30 2016-02-10 Technip France Spar mooring line sharing method and system
FR2945293B1 (fr) * 2009-05-11 2011-06-17 Teoxane Procede de preparation d'un gel reticule.
US9993252B2 (en) 2009-10-26 2018-06-12 Microvention, Inc. Embolization device constructed from expansile polymer
SI2624873T1 (sl) 2010-10-06 2020-07-31 President And Fellows Of Harvard College Injektabilni, pore-formirajoči hidrogeli za celične terapije - na osnovi materialov
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
US11484627B2 (en) 2010-10-20 2022-11-01 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11058796B2 (en) 2010-10-20 2021-07-13 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US20120101593A1 (en) 2010-10-20 2012-04-26 BIOS2 Medical, Inc. Implantable polymer for bone and vascular lesions
WO2015095745A1 (en) 2010-10-20 2015-06-25 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
WO2014190289A2 (en) 2013-05-23 2014-11-27 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
US11291483B2 (en) 2010-10-20 2022-04-05 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
US11207109B2 (en) 2010-10-20 2021-12-28 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US10525169B2 (en) 2010-10-20 2020-01-07 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US9456823B2 (en) 2011-04-18 2016-10-04 Terumo Corporation Embolic devices
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
ES2685327T3 (es) * 2011-04-28 2018-10-08 President And Fellows Of Harvard College Armazones tridimensionales macroscópicos preformados inyectables para administración mínimamente invasiva
WO2012162552A1 (en) 2011-05-26 2012-11-29 Cartiva, Inc. Tapered joint implant and related tools
WO2012167230A1 (en) 2011-06-03 2012-12-06 President And Fellows Of Harvard College In situ antigen-generating cancer vaccine
RU2521194C2 (ru) * 2011-11-16 2014-06-27 Общество с ограниченной ответственностью предприятие "Репер" Матрица для клеточной трансплантологии
EP2819620A4 (en) 2012-02-29 2015-11-04 206 Ortho Inc METHOD AND APPARATUS FOR TREATING BONE FRACTURES, INCLUDING THE USE OF COMPOSITE IMPLANTS
CN102600067B (zh) * 2012-04-10 2013-08-21 武汉大学 含氨基葡萄糖单元的糖肽水凝胶的制备方法及其在制备术后疤痕抑制剂上的应用
ES2773895T3 (es) 2012-04-16 2020-07-15 Harvard College Composiciones de sílice mesoporosa para modular las respuestas inmunitarias
DE102012019984A1 (de) * 2012-10-11 2014-04-17 Leibniz-Institut für Oberflächenmodifizierung e.V. Verfahren zur Herstellung von porösen Gelen mit inkorporierten katalytisch oder biologisch aktiven Materialien sowie damit hergestellte Gele und deren Verwendung
EP2931327B1 (en) 2012-12-11 2019-02-13 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
JP6599361B2 (ja) 2014-04-29 2019-10-30 マイクロベンション インコーポレイテッド 活性剤を含むポリマー
EP3137105A4 (en) 2014-04-30 2017-12-27 President and Fellows of Harvard College Combination vaccine devices and methods of killing cancer cells
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
US9947242B2 (en) * 2014-07-22 2018-04-17 Synaptive Medical (Barbados) Inc. Method for producing anatomical phantoms with constituents having variable densities
JP2017526432A (ja) * 2014-08-14 2017-09-14 ザ・セカント・グループ・エルエルシー 移植可能な物品を製造するために有用な組成物、方法、及び装置
HK1247861A1 (zh) 2015-01-30 2018-10-05 President And Fellows Of Harvard College 用於癌症治疗的肿瘤周围和肿瘤内部材料
EP3753531A1 (en) 2015-03-31 2020-12-23 Cartiva, Inc. Hydrogel implants with porous materials
EP3636226A1 (en) 2015-03-31 2020-04-15 Cartiva, Inc. Carpometacarpal (cmc) implants
CN114099793A (zh) 2015-04-10 2022-03-01 哈佛学院院长等 免疫细胞捕获装置及其制备和使用方法
CA2981074C (en) 2015-04-14 2023-03-28 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
RU2594427C1 (ru) * 2015-06-10 2016-08-20 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) Композиция для формирования макропористого носителя, используемого при трехмерном культивировании клеток животных или человека, и способ получения указанного носителя
WO2016201250A1 (en) 2015-06-11 2016-12-15 Microvention, Inc. Expansile device for implantation
NZ783685A (en) 2015-12-30 2025-09-26 Kodiak Sciences Inc Antibodies and conjugates thereof
DE102016000458A1 (de) * 2016-01-12 2017-07-27 Friedrich-Schiller-Universität Jena Poröse Glycopolymer-funktionalisierte Cryogele und deren Verwendung
WO2017136837A1 (en) 2016-02-06 2017-08-10 President And Fellows Of Harvard College Recapitulating the hematopoietic niche to reconstitute immunity
EP4606890A3 (en) 2016-07-13 2025-12-03 President and Fellows of Harvard College Antigen-presenting cell-mimetic scaffolds and methods for making and using the same
KR102638898B1 (ko) 2016-08-02 2024-02-22 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 면역 반응을 조정하기 위한 생체재료
WO2018165327A1 (en) 2017-03-08 2018-09-13 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
CN107096065B (zh) * 2017-04-05 2019-11-15 浙江大学 含多聚唾液酸复合纳米纤维膜及制备方法和应用
CN108187137A (zh) * 2018-02-27 2018-06-22 崔友军 一种可生物降解神经修复支架的制备方法
SG11202008242XA (en) 2018-03-02 2020-09-29 Kodiak Sciences Inc Il-6 antibodies and fusion constructs and conjugates thereof
WO2020061129A1 (en) 2018-09-19 2020-03-26 President And Fellows Of Harvard College Compositions and methods for labeling and modulation of cells in vitro and in vivo
PL241064B1 (pl) 2018-10-01 2022-08-01 Dolniak Blazej Sposób wytwarzania lepko-sprężystego żelu uzupełniającego maź stawową i lepko-sprężysty żel uzupełniający maź stawową
EP4034148A4 (en) 2019-09-23 2025-09-10 Harvard College BIOMATERIAL-BASED ANTIGEN-FREE VACCINE AND ITS USE
AU2020364071A1 (en) 2019-10-10 2022-05-26 Kodiak Sciences Inc. Methods of treating an eye disorder
EP4084802A4 (en) * 2020-01-03 2024-03-13 Repertoire Immune Medicines, Inc. HYDROGEL COMPOSITIONS AND METHODS OF USE
FR3108260B1 (fr) * 2020-03-17 2024-01-05 Neurobiomat Hydrogel hétérogène hybride, procédé de fabrication et utilisation comme implant de comblement non-dégradable in-situ
CN113599566B (zh) * 2021-08-30 2022-10-25 重庆市沙坪坝区中智医谷研究院 一种疏水性高分子止血修复材料、其制备方法及应用
CN113729654B (zh) * 2021-09-14 2023-03-28 华中科技大学 术后皮瓣与重建肢体血流状态检测表皮贴附式传感系统
DE102023131358A1 (de) * 2023-11-09 2025-05-15 INM - Leibniz-Institut für Neue Materialien gemeinnützige Gesellschaft mit beschränkter Haftung Selbst-schmierende Kontaktlinsen
CN120757703B (zh) * 2025-09-09 2025-12-02 天津大学 一种基于两性离子聚合物的水凝胶睾丸假体及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418772D0 (en) * 1984-07-24 1984-08-30 Geistlich Soehne Ag Chemical substances
GB8422950D0 (en) * 1984-09-11 1984-10-17 Warne K J Hydrogel
US4902295A (en) * 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
US5266325A (en) * 1990-09-28 1993-11-30 Hydro Med Science Division Of National Patent Development Corp. Preparation of homogeneous hydrogel copolymers

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EP0929323B1 (en) 2004-12-15
US5863551A (en) 1999-01-26
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IL124894A0 (en) 1999-01-26
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PL327454A1 (en) 1998-12-07
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