DK1133496T3 - Krystalmodifikation A af 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyre - Google Patents

Krystalmodifikation A af 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyre

Info

Publication number
DK1133496T3
DK1133496T3 DK99958040T DK99958040T DK1133496T3 DK 1133496 T3 DK1133496 T3 DK 1133496T3 DK 99958040 T DK99958040 T DK 99958040T DK 99958040 T DK99958040 T DK 99958040T DK 1133496 T3 DK1133496 T3 DK 1133496T3
Authority
DK
Denmark
Prior art keywords
quinolinecarboxylic
nonan
diazabicyclo
cyclopropyl
dihydro
Prior art date
Application number
DK99958040T
Other languages
Danish (da)
English (en)
Inventor
Thomas Himmler
Werner Hallenbach
Hubert Rast
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Application granted granted Critical
Publication of DK1133496T3 publication Critical patent/DK1133496T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK99958040T 1998-11-25 1999-11-15 Krystalmodifikation A af 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyre DK1133496T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19854356A DE19854356A1 (de) 1998-11-25 1998-11-25 Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Publications (1)

Publication Number Publication Date
DK1133496T3 true DK1133496T3 (da) 2004-08-09

Family

ID=7888960

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99958040T DK1133496T3 (da) 1998-11-25 1999-11-15 Krystalmodifikation A af 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyre

Country Status (27)

Country Link
US (1) US6436955B1 (cs)
EP (1) EP1133496B1 (cs)
JP (1) JP2002530406A (cs)
KR (1) KR100740947B1 (cs)
CN (1) CN1135230C (cs)
AR (1) AR031216A1 (cs)
AT (1) ATE264858T1 (cs)
AU (1) AU763883B2 (cs)
BR (1) BRPI9915669B8 (cs)
CA (1) CA2351712C (cs)
CZ (1) CZ300016B6 (cs)
DE (2) DE19854356A1 (cs)
DK (1) DK1133496T3 (cs)
ES (1) ES2217843T3 (cs)
HK (1) HK1042703B (cs)
HU (1) HUP0104465A3 (cs)
IL (2) IL142696A0 (cs)
NO (1) NO318066B1 (cs)
NZ (1) NZ511861A (cs)
PL (1) PL196085B1 (cs)
PT (1) PT1133496E (cs)
RU (1) RU2247122C2 (cs)
SK (1) SK285540B6 (cs)
TR (1) TR200101438T2 (cs)
TW (1) TW576835B (cs)
UA (1) UA67874C2 (cs)
WO (1) WO2000031075A1 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE102004015981A1 (de) 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
CR20190370A (es) 2017-02-13 2019-10-21 Bayer Animal Health Gmbh Composición líquida que contiene pradofloxacina

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2676521B2 (ja) * 1988-03-22 1997-11-17 北陸製薬株式会社 キノロンカルボン酸化合物ｉ型結晶の製造法
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
HUT77946A (hu) 1994-11-18 1998-12-28 Pharmacia & Upjohn Co. Fluor-kinolon-származék fizikailag stabil, szilárd formája
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
NZ331468A (en) * 1996-02-23 2000-02-28 Bayer Ag Substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-[4,3.0]-nonan-8-yl)-6-fluoro-1, 4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure

Also Published As

Publication number Publication date
AU1553300A (en) 2000-06-13
PL347786A1 (en) 2002-04-22
CA2351712A1 (en) 2000-06-02
UA67874C2 (uk) 2004-07-15
KR100740947B1 (ko) 2007-07-19
US6436955B1 (en) 2002-08-20
AU763883B2 (en) 2003-07-31
WO2000031075A1 (de) 2000-06-02
PL196085B1 (pl) 2007-12-31
HUP0104465A2 (hu) 2002-04-29
ATE264858T1 (de) 2004-05-15
HUP0104465A3 (en) 2002-12-28
EP1133496B1 (de) 2004-04-21
HK1042703A1 (en) 2002-08-23
DE59909262D1 (de) 2004-05-27
HK1042703B (zh) 2004-12-03
NO318066B1 (no) 2005-01-31
NZ511861A (en) 2002-12-20
CZ20011858A3 (cs) 2001-09-12
BRPI9915669A (pt) 2001-08-14
BRPI9915669B8 (pt) 2021-07-06
CZ300016B6 (cs) 2009-01-14
JP2002530406A (ja) 2002-09-17
KR20010080926A (ko) 2001-08-25
DE19854356A1 (de) 2000-05-31
CN1328558A (zh) 2001-12-26
CN1135230C (zh) 2004-01-21
NO20012460L (no) 2001-05-18
EP1133496A1 (de) 2001-09-19
SK6822001A3 (en) 2001-12-03
IL142696A (en) 2006-04-10
SK285540B6 (sk) 2007-03-01
CA2351712C (en) 2011-07-12
AR031216A1 (es) 2003-09-17
ES2217843T3 (es) 2004-11-01
RU2247122C2 (ru) 2005-02-27
NO20012460D0 (no) 2001-05-18
IL142696A0 (en) 2002-03-10
PT1133496E (pt) 2004-08-31
TW576835B (en) 2004-02-21
BRPI9915669B1 (pt) 2017-07-04
TR200101438T2 (tr) 2001-10-22

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