PL347786A1 - Crystal modification a of 8-cyano-1- cyclopropyl -7-(1s,6s-2, 8-diazabicyclo [4.3.0]nonan -8-yl)-6- fluoro-1, 4-dihydro- 4-oxo-3- quinoline carboxylic acid - Google Patents

Crystal modification a of 8-cyano-1- cyclopropyl -7-(1s,6s-2, 8-diazabicyclo [4.3.0]nonan -8-yl)-6- fluoro-1, 4-dihydro- 4-oxo-3- quinoline carboxylic acid

Info

Publication number
PL347786A1
PL347786A1 PL99347786A PL34778699A PL347786A1 PL 347786 A1 PL347786 A1 PL 347786A1 PL 99347786 A PL99347786 A PL 99347786A PL 34778699 A PL34778699 A PL 34778699A PL 347786 A1 PL347786 A1 PL 347786A1
Authority
PL
Poland
Prior art keywords
nonan
diazabicyclo
cyclopropyl
dihydro
oxo
Prior art date
Application number
PL99347786A
Other versions
PL196085B1 (en
Inventor
Thomas Himmler
Werner Hallenbach
Hubert Rast
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PL347786A1 publication Critical patent/PL347786A1/en
Publication of PL196085B1 publication Critical patent/PL196085B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL347786A 1998-11-25 1999-11-15 Crystal modification a of 8-cyano-1- cyclopropyl -7-(1s,6s-2, 8-diazabicyclo [4.3.0]nonan -8-yl)-6- fluoro-1, 4-dihydro- 4-oxo-3- quinoline carboxylic acid PL196085B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19854356A DE19854356A1 (en) 1998-11-25 1998-11-25 Crystal modification A of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.0 / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
PCT/EP1999/008775 WO2000031075A1 (en) 1998-11-25 1999-11-15 Crystal modification a of 8-cyano-1- cyclopropyl -7-(1s,6s-2, 8-diazabicyclo [4.3.0]nonan -8-yl)-6- fluoro-1, 4-dihydro- 4-oxo-3- quinoline carboxylic acid

Publications (2)

Publication Number Publication Date
PL347786A1 true PL347786A1 (en) 2002-04-22
PL196085B1 PL196085B1 (en) 2007-12-31

Family

ID=7888960

Family Applications (1)

Application Number Title Priority Date Filing Date
PL347786A PL196085B1 (en) 1998-11-25 1999-11-15 Crystal modification a of 8-cyano-1- cyclopropyl -7-(1s,6s-2, 8-diazabicyclo [4.3.0]nonan -8-yl)-6- fluoro-1, 4-dihydro- 4-oxo-3- quinoline carboxylic acid

Country Status (27)

Country Link
US (1) US6436955B1 (en)
EP (1) EP1133496B1 (en)
JP (1) JP2002530406A (en)
KR (1) KR100740947B1 (en)
CN (1) CN1135230C (en)
AR (1) AR031216A1 (en)
AT (1) ATE264858T1 (en)
AU (1) AU763883B2 (en)
BR (1) BRPI9915669B8 (en)
CA (1) CA2351712C (en)
CZ (1) CZ300016B6 (en)
DE (2) DE19854356A1 (en)
DK (1) DK1133496T3 (en)
ES (1) ES2217843T3 (en)
HK (1) HK1042703B (en)
HU (1) HUP0104465A3 (en)
IL (2) IL142696A0 (en)
NO (1) NO318066B1 (en)
NZ (1) NZ511861A (en)
PL (1) PL196085B1 (en)
PT (1) PT1133496E (en)
RU (1) RU2247122C2 (en)
SK (1) SK285540B6 (en)
TR (1) TR200101438T2 (en)
TW (1) TW576835B (en)
UA (1) UA67874C2 (en)
WO (1) WO2000031075A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854355A1 (en) 1998-11-25 2000-05-31 Bayer Ag Crystal modification B of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.O / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
DE19908448A1 (en) 1999-02-26 2000-08-31 Bayer Ag Crystal modification D of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicylo [4.3.0) nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3 -chino incarboxylic acid
DE19908449A1 (en) 1999-02-26 2000-08-31 Bayer Ag Crystal modification C of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicylo- [4.3.0] nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-chino / incarboxylic acid
DE102004015981A1 (en) * 2004-04-01 2005-10-20 Bayer Healthcare Ag New kirstalline form of 8-cyano-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo [4.3.0] nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinolinecarboxylic
RU2019128568A (en) 2017-02-13 2021-03-15 Байер Энимэл Хельс ГмбХ LIQUID COMPOSITION CONTAINING PRADOFLOXACIN

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2676521B2 (en) * 1988-03-22 1997-11-17 北陸製薬株式会社 Method for producing quinolonecarboxylic acid compound type I crystal
DE3906365A1 (en) * 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
DE3910663A1 (en) * 1989-04-03 1990-10-04 Bayer Ag 5-ALKYLCHINOLON CARBONIC ACIDS
AU709057B2 (en) 1994-11-18 1999-08-19 Pharmacia & Upjohn Company A new physically stable solid form of a fluoroquinolone
DE19546249A1 (en) * 1995-12-12 1997-06-19 Bayer Ag New crystal modification of 1-cyclopropyl-7 - ([S, S] -2,8-diazabicyclo [4,3,0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4 -oxo-3-quinoline carboxylic acid hydrochloride (CDCH), process for its preparation and pharmaceutical preparations containing it
DE19633805A1 (en) 1996-02-23 1997-08-28 Bayer Ag Optionally substituted 8-cyano-l-cyclopropyl-7- (2,8-diazabicyclo- [4.3.0] -nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and their derivatives
DE59708771D1 (en) * 1996-02-23 2003-01-02 Bayer Ag SUBSTITUTED 8-CYAN-1-CYCLOPROPYL-7- (2,8-DIAZABICYCLO- 4.3.0] -NONAN-8-YL) -6-FLUOR-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS AND YOUR DERIVATIVES
DE19854355A1 (en) 1998-11-25 2000-05-31 Bayer Ag Crystal modification B of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.O / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
DE19908448A1 (en) 1999-02-26 2000-08-31 Bayer Ag Crystal modification D of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicylo [4.3.0) nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3 -chino incarboxylic acid
DE19908449A1 (en) 1999-02-26 2000-08-31 Bayer Ag Crystal modification C of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicylo- [4.3.0] nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-chino / incarboxylic acid

Also Published As

Publication number Publication date
BRPI9915669B1 (en) 2017-07-04
HUP0104465A2 (en) 2002-04-29
NO20012460L (en) 2001-05-18
US6436955B1 (en) 2002-08-20
CZ300016B6 (en) 2009-01-14
EP1133496B1 (en) 2004-04-21
CZ20011858A3 (en) 2001-09-12
NZ511861A (en) 2002-12-20
KR100740947B1 (en) 2007-07-19
CN1135230C (en) 2004-01-21
EP1133496A1 (en) 2001-09-19
PL196085B1 (en) 2007-12-31
HK1042703B (en) 2004-12-03
IL142696A0 (en) 2002-03-10
CA2351712A1 (en) 2000-06-02
TR200101438T2 (en) 2001-10-22
DK1133496T3 (en) 2004-08-09
WO2000031075A1 (en) 2000-06-02
BRPI9915669A (en) 2001-08-14
ES2217843T3 (en) 2004-11-01
NO318066B1 (en) 2005-01-31
NO20012460D0 (en) 2001-05-18
JP2002530406A (en) 2002-09-17
TW576835B (en) 2004-02-21
SK6822001A3 (en) 2001-12-03
ATE264858T1 (en) 2004-05-15
AR031216A1 (en) 2003-09-17
KR20010080926A (en) 2001-08-25
AU1553300A (en) 2000-06-13
DE19854356A1 (en) 2000-05-31
CN1328558A (en) 2001-12-26
IL142696A (en) 2006-04-10
DE59909262D1 (en) 2004-05-27
CA2351712C (en) 2011-07-12
HK1042703A1 (en) 2002-08-23
UA67874C2 (en) 2004-07-15
SK285540B6 (en) 2007-03-01
BRPI9915669B8 (en) 2021-07-06
HUP0104465A3 (en) 2002-12-28
RU2247122C2 (en) 2005-02-27
AU763883B2 (en) 2003-07-31
PT1133496E (en) 2004-08-31

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LAPS Decisions on the lapse of the protection rights

Effective date: 20121115