DK1117642T3 - Substituerede 1,3-diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)-propanolderivater, fremgangsmåder til fremstilling deraf, farmaceutiske præparater indeholdende dem og anvendelse deraf - Google Patents
Substituerede 1,3-diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)-propanolderivater, fremgangsmåder til fremstilling deraf, farmaceutiske præparater indeholdende dem og anvendelse derafInfo
- Publication number
- DK1117642T3 DK1117642T3 DK99948791T DK99948791T DK1117642T3 DK 1117642 T3 DK1117642 T3 DK 1117642T3 DK 99948791 T DK99948791 T DK 99948791T DK 99948791 T DK99948791 T DK 99948791T DK 1117642 T3 DK1117642 T3 DK 1117642T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyridin
- ylamino
- diaryl
- substituted
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19845406A DE19845406C2 (de) | 1998-10-02 | 1998-10-02 | Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1117642T3 true DK1117642T3 (da) | 2004-08-09 |
Family
ID=7883187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99948791T DK1117642T3 (da) | 1998-10-02 | 1999-09-18 | Substituerede 1,3-diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)-propanolderivater, fremgangsmåder til fremstilling deraf, farmaceutiske præparater indeholdende dem og anvendelse deraf |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6596728B1 (da) |
| EP (1) | EP1117642B1 (da) |
| JP (1) | JP4544746B2 (da) |
| KR (1) | KR100609255B1 (da) |
| CN (1) | CN1173951C (da) |
| AR (1) | AR021845A1 (da) |
| AT (1) | ATE267809T1 (da) |
| AU (1) | AU757689B2 (da) |
| BR (1) | BR9915027B1 (da) |
| CA (1) | CA2345985C (da) |
| CZ (1) | CZ299569B6 (da) |
| DE (2) | DE19845406C2 (da) |
| DK (1) | DK1117642T3 (da) |
| ES (1) | ES2219066T3 (da) |
| HK (1) | HK1051533A1 (da) |
| HU (1) | HU226688B1 (da) |
| ID (1) | ID29249A (da) |
| PL (1) | PL205034B1 (da) |
| PT (1) | PT1117642E (da) |
| RU (1) | RU2224748C2 (da) |
| TR (1) | TR200100896T2 (da) |
| WO (1) | WO2000020393A1 (da) |
| ZA (1) | ZA200102587B (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ20031733A3 (cs) | 2000-12-21 | 2003-09-17 | Aventis Pharma Deutschland Gmbh | Difenylazetidinonové deriváty a farmaceutické prostředky s jejich obsahem |
| NZ531292A (en) * | 2001-08-22 | 2005-08-26 | Aventis Pharma Gmbh | Combination products of aryl-subsituted propanolamine derivatives with other active ingredients and the use thereof |
| DE10219987A1 (de) * | 2002-05-03 | 2004-04-08 | Aventis Pharma Deutschland Gmbh | Optisch aktive β-Aminoketone, optisch aktive 1,3-Aminoalkohole und Verfahren zu deren Herstellung |
| US7161008B2 (en) * | 2002-05-03 | 2007-01-09 | Sanofi - Aventis Deutschland GmbH | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them |
| GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
| JP4800216B2 (ja) * | 2003-10-24 | 2011-10-26 | エグゼリクシス， インコーポレイテッド | ｐ７０Ｓ６キナーゼモジュレーターおよび使用方法 |
| EP2575821B1 (en) | 2010-05-26 | 2015-08-12 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
| CN107375932B (zh) | 2011-10-28 | 2021-12-21 | 夏尔人类遗传性治疗公司 | 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂 |
| EA029581B1 (ru) | 2011-10-28 | 2018-04-30 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Применение ингибиторов рециркуляции желчных кислот для лечения холестатического заболевания печени или прурита |
| CA2907230A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease |
| EP2968262A1 (en) | 2013-03-15 | 2016-01-20 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease |
| JP6361168B2 (ja) * | 2013-06-17 | 2018-07-25 | Jsr株式会社 | 液晶配向剤、液晶配向膜、液晶表示素子、液晶表示素子の製造方法、重合体及び化合物 |
| MX2021009622A (es) | 2019-02-12 | 2021-11-04 | Mirum Pharmaceuticals Inc | Metodos para tratar la colestasis. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0000816A1 (en) * | 1977-08-06 | 1979-02-21 | Beecham Group Plc | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them |
| DK0869121T3 (da) | 1997-04-04 | 2004-09-20 | Aventis Pharma Gmbh | Hypolipidæmiske propanolaminderivater |
| DE19845402B4 (de) * | 1998-10-02 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| DE19845405C2 (de) * | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
-
1998
- 1998-10-02 DE DE19845406A patent/DE19845406C2/de not_active Expired - Fee Related
-
1999
- 1999-09-18 WO PCT/EP1999/006933 patent/WO2000020393A1/de active IP Right Grant
- 1999-09-18 PL PL347096A patent/PL205034B1/pl unknown
- 1999-09-18 BR BRPI9915027-1A patent/BR9915027B1/pt not_active IP Right Cessation
- 1999-09-18 ID IDW20010736A patent/ID29249A/id unknown
- 1999-09-18 ES ES99948791T patent/ES2219066T3/es not_active Expired - Lifetime
- 1999-09-18 TR TR2001/00896T patent/TR200100896T2/xx unknown
- 1999-09-18 HU HU0103533A patent/HU226688B1/hu not_active IP Right Cessation
- 1999-09-18 CN CNB99811636XA patent/CN1173951C/zh not_active Expired - Fee Related
- 1999-09-18 RU RU2001111841/04A patent/RU2224748C2/ru not_active IP Right Cessation
- 1999-09-18 AU AU61926/99A patent/AU757689B2/en not_active Ceased
- 1999-09-18 CA CA2345985A patent/CA2345985C/en not_active Expired - Fee Related
- 1999-09-18 CZ CZ20011152A patent/CZ299569B6/cs not_active IP Right Cessation
- 1999-09-18 AT AT99948791T patent/ATE267809T1/de active
- 1999-09-18 EP EP99948791A patent/EP1117642B1/de not_active Expired - Lifetime
- 1999-09-18 PT PT99948791T patent/PT1117642E/pt unknown
- 1999-09-18 DE DE59909606T patent/DE59909606D1/de not_active Expired - Lifetime
- 1999-09-18 JP JP2000574510A patent/JP4544746B2/ja not_active Expired - Fee Related
- 1999-09-18 DK DK99948791T patent/DK1117642T3/da active
- 1999-09-18 KR KR1020017004096A patent/KR100609255B1/ko not_active IP Right Cessation
- 1999-09-30 AR ARP990104960A patent/AR021845A1/es active IP Right Grant
- 1999-10-01 US US09/410,083 patent/US6596728B1/en not_active Expired - Lifetime
-
2001
- 2001-03-29 ZA ZA200102587A patent/ZA200102587B/en unknown
-
2003
- 2003-05-27 HK HK03103726A patent/HK1051533A1/xx not_active IP Right Cessation
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