DK1116719T3 - 3-(1-hydroxy-pentyliden)-5-nitro-3H-benzofuran-2-on, fremgangsmåde til fremstilling deraf og anvendelse deraf - Google Patents
3-(1-hydroxy-pentyliden)-5-nitro-3H-benzofuran-2-on, fremgangsmåde til fremstilling deraf og anvendelse derafInfo
- Publication number
- DK1116719T3 DK1116719T3 DK01810033T DK01810033T DK1116719T3 DK 1116719 T3 DK1116719 T3 DK 1116719T3 DK 01810033 T DK01810033 T DK 01810033T DK 01810033 T DK01810033 T DK 01810033T DK 1116719 T3 DK1116719 T3 DK 1116719T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- pentylidene
- benzofuran
- nitro
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0000523A FR2803846B1 (fr) | 2000-01-17 | 2000-01-17 | 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation |
EP01810033A EP1116719B1 (fr) | 2000-01-17 | 2001-01-15 | 3-(1-Hydroxy-pentylidène)-5-nitro-3H-benzofuran-2-one, procédé de sa préparation et son utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1116719T3 true DK1116719T3 (da) | 2005-07-18 |
Family
ID=8845968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01810033T DK1116719T3 (da) | 2000-01-17 | 2001-01-15 | 3-(1-hydroxy-pentyliden)-5-nitro-3H-benzofuran-2-on, fremgangsmåde til fremstilling deraf og anvendelse deraf |
Country Status (13)
Country | Link |
---|---|
US (2) | US6515147B2 (fr) |
EP (1) | EP1116719B1 (fr) |
JP (1) | JP4408578B2 (fr) |
KR (1) | KR100788529B1 (fr) |
CN (1) | CN1204133C (fr) |
AT (1) | ATE292630T1 (fr) |
DE (1) | DE60109829T2 (fr) |
DK (1) | DK1116719T3 (fr) |
ES (1) | ES2238408T3 (fr) |
FR (1) | FR2803846B1 (fr) |
HU (1) | HUP0100146A3 (fr) |
NO (1) | NO327039B1 (fr) |
TW (1) | TW564246B (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10237819A1 (de) * | 2002-08-19 | 2004-03-04 | Bayer Ag | 5-Nitrobenzofurane |
FR2864536B1 (fr) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
GB0719180D0 (en) | 2007-10-02 | 2007-11-14 | Cambrex Karlskoga Ab | New process |
FR2930149B1 (fr) * | 2008-04-17 | 2011-02-18 | Sanofi Aventis | Association de dronedarone avec au moins un diuretique, son application en therapeutique |
EP2684564A1 (fr) * | 2008-04-17 | 2014-01-15 | Sanofi | Utilisation de dronédarone dans un médicament utilisé pour prévenir un épisode cardiovasculaire menant à l' hospitalisation ou prévenir la fibrillation auriculaire |
EP2116239A1 (fr) * | 2008-04-29 | 2009-11-11 | Sanofi-Aventis | Procédé pour la gestion des risques associés à une augmentation de la créatinine sérique pendant un traitement à la dronédarone |
EP2246341A1 (fr) | 2009-01-23 | 2010-11-03 | Lonza Ltd. | Processus de préparation de 2-Alkyl-3-aroyl-5-nitro-benzofuranes |
CN102276561A (zh) * | 2010-06-09 | 2011-12-14 | 江苏恒瑞医药股份有限公司 | 决奈达隆及其盐的制备方法 |
US8602215B2 (en) | 2010-06-30 | 2013-12-10 | Sanofi | Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3248401A (en) * | 1966-04-26 | Diethylaminoe hoxybenzoyl benzofurans | ||
US4252817A (en) * | 1975-03-12 | 1981-02-24 | Sandoz Ltd. | Substituted-2,3-dihydrobenzofuran-2-ones |
FR2642755B1 (fr) * | 1989-02-07 | 1993-11-05 | Sanofi | |
FR2665444B1 (fr) * | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
GB9416219D0 (en) * | 1994-08-11 | 1994-10-05 | Karobio Ab | Receptor ligands |
-
2000
- 2000-01-17 FR FR0000523A patent/FR2803846B1/fr not_active Expired - Fee Related
-
2001
- 2001-01-10 TW TW090100495A patent/TW564246B/zh not_active IP Right Cessation
- 2001-01-15 HU HU0100146A patent/HUP0100146A3/hu unknown
- 2001-01-15 AT AT01810033T patent/ATE292630T1/de active
- 2001-01-15 ES ES01810033T patent/ES2238408T3/es not_active Expired - Lifetime
- 2001-01-15 EP EP01810033A patent/EP1116719B1/fr not_active Expired - Lifetime
- 2001-01-15 DK DK01810033T patent/DK1116719T3/da active
- 2001-01-15 DE DE60109829T patent/DE60109829T2/de not_active Expired - Lifetime
- 2001-01-16 KR KR1020010002333A patent/KR100788529B1/ko not_active IP Right Cessation
- 2001-01-16 JP JP2001007465A patent/JP4408578B2/ja not_active Expired - Fee Related
- 2001-01-16 NO NO20010265A patent/NO327039B1/no not_active IP Right Cessation
- 2001-01-17 US US09/761,452 patent/US6515147B2/en not_active Ceased
- 2001-01-17 CN CNB01101296XA patent/CN1204133C/zh not_active Expired - Fee Related
-
2005
- 2005-02-03 US US11/050,627 patent/USRE39755E1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP4408578B2 (ja) | 2010-02-03 |
EP1116719A3 (fr) | 2001-10-24 |
ES2238408T3 (es) | 2005-09-01 |
ATE292630T1 (de) | 2005-04-15 |
HU0100146D0 (en) | 2001-03-28 |
USRE39755E1 (en) | 2007-07-31 |
CN1306000A (zh) | 2001-08-01 |
HUP0100146A2 (hu) | 2002-01-28 |
NO327039B1 (no) | 2009-04-06 |
KR20010076278A (ko) | 2001-08-11 |
DE60109829D1 (de) | 2005-05-12 |
NO20010265L (no) | 2001-07-18 |
DE60109829T2 (de) | 2006-01-19 |
KR100788529B1 (ko) | 2007-12-24 |
US6515147B2 (en) | 2003-02-04 |
EP1116719A2 (fr) | 2001-07-18 |
EP1116719B1 (fr) | 2005-04-06 |
JP2001233870A (ja) | 2001-08-28 |
CN1204133C (zh) | 2005-06-01 |
FR2803846B1 (fr) | 2002-04-05 |
TW564246B (en) | 2003-12-01 |
HUP0100146A3 (en) | 2003-07-28 |
NO20010265D0 (no) | 2001-01-16 |
FR2803846A1 (fr) | 2001-07-20 |
US20010012900A1 (en) | 2001-08-09 |
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