DK1102588T3 - Farmaceutiske sammensætninger til forebyggelse og behandling af sygdomme i centralnervesystemet indeholdende en nikotinanalog og en acetylcholinesteraseinhibitor - Google Patents
Farmaceutiske sammensætninger til forebyggelse og behandling af sygdomme i centralnervesystemet indeholdende en nikotinanalog og en acetylcholinesteraseinhibitorInfo
- Publication number
- DK1102588T3 DK1102588T3 DK99965348T DK99965348T DK1102588T3 DK 1102588 T3 DK1102588 T3 DK 1102588T3 DK 99965348 T DK99965348 T DK 99965348T DK 99965348 T DK99965348 T DK 99965348T DK 1102588 T3 DK1102588 T3 DK 1102588T3
- Authority
- DK
- Denmark
- Prior art keywords
- acetylcholinesterase inhibitor
- prevention
- treatment
- pharmaceutical compositions
- nervous system
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/130,498 US6218383B1 (en) | 1998-08-07 | 1998-08-07 | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
PCT/US1999/012243 WO2000007600A1 (fr) | 1998-08-07 | 1999-06-02 | Compositions pharmaceutiques de prevention et de traitement de troubles du systeme nerveux central |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1102588T3 true DK1102588T3 (da) | 2009-04-14 |
Family
ID=22444976
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08019914.4T DK2018874T3 (da) | 1998-08-07 | 1999-06-02 | Farmaceutiske sammensætninger til forebyggelse og behandling af lidelser i centralnervesystemet indeholdende en nikotinisk agonist og en acetylcholinesteraseinhibitor |
DK99965348T DK1102588T3 (da) | 1998-08-07 | 1999-06-02 | Farmaceutiske sammensætninger til forebyggelse og behandling af sygdomme i centralnervesystemet indeholdende en nikotinanalog og en acetylcholinesteraseinhibitor |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08019914.4T DK2018874T3 (da) | 1998-08-07 | 1999-06-02 | Farmaceutiske sammensætninger til forebyggelse og behandling af lidelser i centralnervesystemet indeholdende en nikotinisk agonist og en acetylcholinesteraseinhibitor |
Country Status (16)
Country | Link |
---|---|
US (1) | US6218383B1 (fr) |
EP (2) | EP2018874B1 (fr) |
JP (2) | JP4750945B2 (fr) |
KR (1) | KR100705434B1 (fr) |
AT (1) | ATE418986T1 (fr) |
AU (1) | AU761087B2 (fr) |
BR (1) | BR9912805A (fr) |
CA (1) | CA2335012C (fr) |
CY (2) | CY1110309T1 (fr) |
DE (1) | DE69940199D1 (fr) |
DK (2) | DK2018874T3 (fr) |
ES (2) | ES2515120T3 (fr) |
HK (1) | HK1127290A1 (fr) |
MX (1) | MXPA01001435A (fr) |
PT (2) | PT2018874E (fr) |
WO (1) | WO2000007600A1 (fr) |
Families Citing this family (51)
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US7790757B2 (en) * | 1998-06-16 | 2010-09-07 | Targacept, Inc. | Compounds capable of activating cholinergic receptors |
US6232316B1 (en) | 1998-06-16 | 2001-05-15 | Targacept, Inc. | Methods for treatment of CNS disorders |
US20050131034A1 (en) * | 1998-06-16 | 2005-06-16 | Caldwell William S. | Compounds capable of activating cholinergic receptors |
US20010031771A1 (en) | 1999-05-24 | 2001-10-18 | Gary Maurice Dull | Pharmaceutical compositions and methods for use |
WO2000075110A1 (fr) * | 1999-06-07 | 2000-12-14 | Targacept, Inc. | Compositions pharmaceutiques et methodes d'utilisation |
US20010036949A1 (en) * | 2000-05-09 | 2001-11-01 | Coe Jotham Wadsworth | Pharmaceutical composition and method of treatment of diseases of cognitive dysfunction in a mammal |
US20020016334A1 (en) * | 2000-07-31 | 2002-02-07 | Coe Jotham Wadsworth | Pharmaceutical composition for the treatment of attention deficit hyperactivity disorder (ADHD) |
AU2002360598B2 (en) * | 2001-12-14 | 2008-02-14 | Medical College Of Georgia Research Institute, Inc. | Methods and compositions for treatment of central nervous system disorders |
US7091357B2 (en) | 2001-12-26 | 2006-08-15 | University Of Kentucky Research Foundation | Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies |
US6852741B2 (en) * | 2001-12-31 | 2005-02-08 | University Of Florida | Compositions and methods for treatment of neurological disorders |
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US20030186860A1 (en) * | 2002-03-29 | 2003-10-02 | Welsh Michael J. | Novel compositions and methods for modulating the acid-sensing ion channel (ASIC) |
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US8580842B2 (en) | 2003-09-30 | 2013-11-12 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
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ATE554085T1 (de) | 2006-11-30 | 2012-05-15 | Probiodrug Ag | Neue inhibitoren von glutaminylcyclase |
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US8486979B2 (en) | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
UY30846A1 (es) | 2006-12-30 | 2008-07-31 | Abbott Gmbh & Amp | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos |
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EP2481408A3 (fr) | 2007-03-01 | 2013-01-09 | Probiodrug AG | Nouvelle utilisation d'inhibiteurs glutaminyle cyclase |
EP2865670B1 (fr) | 2007-04-18 | 2017-01-11 | Probiodrug AG | Dérivés de thio-urée utilisés comme inhibiteurs de la glutaminyl cyclase |
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US20090291150A1 (en) * | 2008-05-21 | 2009-11-26 | University Of Iowa Research Foundation | Method and compositions for treating and preventing seizures by modulating acid-sensing ion channel activity |
US9801865B2 (en) | 2008-09-24 | 2017-10-31 | The United States Of America As Represented By The Department Of Veteran Affairs | Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with abeta peptide aggregation |
US9040568B2 (en) | 2009-05-29 | 2015-05-26 | Abbvie Inc. | Pharmaceutical compositions for the treatment of pain |
US20110212928A1 (en) | 2010-02-09 | 2011-09-01 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
ES2586231T3 (es) | 2010-03-03 | 2016-10-13 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
CN102791704B (zh) | 2010-03-10 | 2015-11-25 | 前体生物药物股份公司 | 谷氨酰胺酰环化酶(qc, ec 2.3.2.5)的杂环抑制剂 |
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US10806717B2 (en) | 2013-03-15 | 2020-10-20 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
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JP6899043B2 (ja) | 2015-05-22 | 2021-07-07 | エージンバイオ, インコーポレイテッド | レベチラセタムの持続放出性医薬組成物 |
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JP2668670B2 (ja) * | 1995-03-24 | 1997-10-27 | 日本たばこ産業株式会社 | ジアザビシクロ[3.3.1]ノナン誘導体、その中間体及びその医薬用途 |
AU5014396A (en) | 1995-03-24 | 1996-10-16 | Japan Tobacco Inc. | Diazabicyclo{3.3.1}nonane derivatives and intermediates ther eof, medicinal use of the same, and processes for producing the same |
US5585388A (en) | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
US5583140A (en) | 1995-05-17 | 1996-12-10 | Bencherif; Merouane | Pharmaceutical compositions for the treatment of central nervous system disorders |
IL118279A (en) | 1995-06-07 | 2006-10-05 | Abbott Lab | Compounds 3 - Pyridyloxy (or Thio) Alkyl Heterocyclic Pharmaceutical Compositions Containing Them and Their Uses for Preparing Drugs to Control Synaptic Chemical Transmission |
EP0874818B1 (fr) | 1995-11-17 | 2003-05-21 | MERCK & CO. INC. | Nouveaux composes d'aryle substitues utiles comme modulateurs des recepteurs de l'acetylcholine |
US5616716A (en) | 1996-01-06 | 1997-04-01 | Dull; Gary M. | (3-(5-ethoxypyridin)yl)-alkenyl 1 amine compounds |
ATE207483T1 (de) | 1996-04-12 | 2001-11-15 | Aventis Pharma Inc | Isatinderivate als acetylcholinesterase- inhibitoren und analgetika |
US5663356A (en) | 1996-04-23 | 1997-09-02 | Ruecroft; Graham | Method for preparation of aryl substituted alefinic secondary amino compounds |
CA2180703A1 (fr) | 1996-07-08 | 1998-01-09 | Paul Marie Victor Gilis | Comprime de bromhydrate de galanthamine a dissolution rapide |
EP0984965B1 (fr) * | 1997-05-30 | 2004-05-19 | Neurosearch A/S | Derives de 8-azabicyclo 3.2.1]oct-2-ene et -octane utilises comme ligands cholinergiques de recepteurs nicotiniques de l'ach |
US7727473B2 (en) | 2005-10-19 | 2010-06-01 | Progentech Limited | Cassette for sample preparation |
JP5597919B2 (ja) * | 2008-11-05 | 2014-10-01 | 株式会社三洋物産 | 制御基板の収納構造 |
-
1998
- 1998-08-07 US US09/130,498 patent/US6218383B1/en not_active Expired - Lifetime
-
1999
- 1999-06-02 JP JP2000563285A patent/JP4750945B2/ja not_active Expired - Fee Related
- 1999-06-02 BR BR9912805-5A patent/BR9912805A/pt not_active Application Discontinuation
- 1999-06-02 DE DE69940199T patent/DE69940199D1/de not_active Expired - Lifetime
- 1999-06-02 CA CA002335012A patent/CA2335012C/fr not_active Expired - Fee Related
- 1999-06-02 EP EP08019914.4A patent/EP2018874B1/fr not_active Expired - Lifetime
- 1999-06-02 DK DK08019914.4T patent/DK2018874T3/da active
- 1999-06-02 EP EP99965348A patent/EP1102588B1/fr not_active Expired - Lifetime
- 1999-06-02 AT AT99965348T patent/ATE418986T1/de active
- 1999-06-02 WO PCT/US1999/012243 patent/WO2000007600A1/fr not_active Application Discontinuation
- 1999-06-02 ES ES08019914.4T patent/ES2515120T3/es not_active Expired - Lifetime
- 1999-06-02 AU AU43285/99A patent/AU761087B2/en not_active Ceased
- 1999-06-02 KR KR1020007014515A patent/KR100705434B1/ko not_active IP Right Cessation
- 1999-06-02 MX MXPA01001435A patent/MXPA01001435A/es not_active IP Right Cessation
- 1999-06-02 DK DK99965348T patent/DK1102588T3/da active
- 1999-06-02 PT PT80199144T patent/PT2018874E/pt unknown
- 1999-06-02 ES ES99965348T patent/ES2322725T3/es not_active Expired - Lifetime
- 1999-06-02 PT PT99965348T patent/PT1102588E/pt unknown
-
2009
- 2009-02-10 CY CY20091100150T patent/CY1110309T1/el unknown
- 2009-06-25 HK HK09105736.9A patent/HK1127290A1/xx not_active IP Right Cessation
-
2011
- 2011-02-24 JP JP2011038189A patent/JP2011137027A/ja active Pending
-
2014
- 2014-09-24 CY CY20141100777T patent/CY1115589T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU761087B2 (en) | 2003-05-29 |
JP4750945B2 (ja) | 2011-08-17 |
CA2335012A1 (fr) | 2000-02-17 |
DK2018874T3 (da) | 2014-10-13 |
ES2322725T3 (es) | 2009-06-25 |
WO2000007600A1 (fr) | 2000-02-17 |
ES2515120T3 (es) | 2014-10-29 |
PT1102588E (pt) | 2009-02-26 |
HK1127290A1 (en) | 2009-09-25 |
US6218383B1 (en) | 2001-04-17 |
AU4328599A (en) | 2000-02-28 |
DE69940199D1 (de) | 2009-02-12 |
PT2018874E (pt) | 2014-10-16 |
CA2335012C (fr) | 2009-08-11 |
CY1115589T1 (el) | 2017-01-04 |
CY1110309T1 (el) | 2015-01-14 |
BR9912805A (pt) | 2001-05-02 |
EP2018874A3 (fr) | 2012-11-21 |
EP1102588A1 (fr) | 2001-05-30 |
KR20010072631A (ko) | 2001-07-31 |
EP2018874A2 (fr) | 2009-01-28 |
ATE418986T1 (de) | 2009-01-15 |
KR100705434B1 (ko) | 2007-04-09 |
MXPA01001435A (es) | 2003-09-10 |
JP2002522390A (ja) | 2002-07-23 |
EP1102588B1 (fr) | 2008-12-31 |
EP2018874B1 (fr) | 2014-08-13 |
JP2011137027A (ja) | 2011-07-14 |
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