DK1096954T3 - Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A - Google Patents

Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A

Info

Publication number
DK1096954T3
DK1096954T3 DK99935566T DK99935566T DK1096954T3 DK 1096954 T3 DK1096954 T3 DK 1096954T3 DK 99935566 T DK99935566 T DK 99935566T DK 99935566 T DK99935566 T DK 99935566T DK 1096954 T3 DK1096954 T3 DK 1096954T3
Authority
DK
Denmark
Prior art keywords
adjuvant
vaccine compositions
monophosphoryl lipid
compositions containing
containing monophosphoryl
Prior art date
Application number
DK99935566T
Other languages
Danish (da)
English (en)
Inventor
Vincent James Laposta
John Hayward Eldridge
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1096954T3 publication Critical patent/DK1096954T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK99935566T 1998-07-14 1999-07-13 Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A DK1096954T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11539298A 1998-07-14 1998-07-14
EP99935566A EP1096954B1 (en) 1998-07-14 1999-07-13 Adjuvant and vaccine compositions containing monophosphoryl lipid a

Publications (1)

Publication Number Publication Date
DK1096954T3 true DK1096954T3 (da) 2005-01-31

Family

ID=22361090

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99935566T DK1096954T3 (da) 1998-07-14 1999-07-13 Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A

Country Status (14)

Country Link
EP (1) EP1096954B1 (ko)
JP (1) JP2002520373A (ko)
KR (1) KR100586804B1 (ko)
CN (1) CN1247262C (ko)
AT (1) ATE278420T1 (ko)
AU (1) AU763770B2 (ko)
BR (1) BR9912067A (ko)
CA (1) CA2333578C (ko)
DE (1) DE69920915T2 (ko)
DK (1) DK1096954T3 (ko)
ES (1) ES2229745T3 (ko)
IL (1) IL140890A0 (ko)
PT (1) PT1096954E (ko)
WO (1) WO2000003744A2 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE353367T1 (de) 1998-12-22 2007-02-15 Microscience Ltd Group b streptococcus proteine und deren verwendung
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
JP5004261B2 (ja) * 2000-05-19 2012-08-22 コリクサ コーポレイション 単糖類及び二糖類に基づく化合物を用いた感染症及び他の疾患の予防的並びに治療的な処置
FR2814956B1 (fr) * 2000-10-06 2003-01-24 Seppic Sa Nouvelle composition vaccinale, procede pour sa preparation, utilisation comme composition injectale en medecine humaine ou veterinaire et nouveau procede de conservation
EP1909830B1 (en) * 2005-08-02 2011-09-28 Novartis Vaccines and Diagnostics S.r.l. Reducing interference between oil-containing adjuvants and surfactant-containing antigens
EP2726097A4 (en) * 2011-07-01 2015-03-11 Univ California HERPES VIRUS VACCINE AND METHOD OF USE
US9241988B2 (en) * 2012-04-12 2016-01-26 Avanti Polar Lipids, Inc. Disaccharide synthetic lipid compounds and uses thereof
EA032441B1 (ru) * 2013-09-05 2019-05-31 Иммьюн Дизайн Корп. Вакцинные композиции против никотиновой зависимости
CN116199727A (zh) * 2021-12-01 2023-06-02 上海安奕康生物科技有限公司 一种mpl三乙胺盐、其制备工艺及应用
WO2023212702A2 (en) * 2022-04-28 2023-11-02 Kansas State University Research Foundation Corralling amphipathic peptide colloids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672496B3 (fr) * 1990-07-18 1993-05-28 Vacsyn France Sa Compositions a base de substances hydrophobes, solubilisables dans un solvant aqueux, leur procede d'obtention, et leurs utilisations notamment dans le domaine pharmaceutique.
PL178578B1 (pl) * 1993-03-23 2000-05-31 Smithkline Beecham Biolog Zawiesina cząstek 3-0-deacylowanego monofosforylolipidu A i sposób jej wytwarzania oraz kompozycja szczepionki zawierającej antygen w połączeniu z 3-0-deacylowanym monofosforylolipidem A i sposób jej wytwarzania
US5565204A (en) * 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5762943A (en) * 1996-05-14 1998-06-09 Ribi Immunochem Research, Inc. Methods of treating type I hypersensitivity using monophosphoryl lipid A
GB9612137D0 (en) * 1996-06-10 1996-08-14 Quaker Oats Co Treatment of dried fruit
DE69733651T2 (de) * 1996-07-03 2006-05-18 Eisai Co., Ltd. Lipid a-analoge enthaltende injektionen und verfahren zu deren herstellung

Also Published As

Publication number Publication date
BR9912067A (pt) 2001-04-10
WO2000003744A2 (en) 2000-01-27
JP2002520373A (ja) 2002-07-09
PT1096954E (pt) 2004-12-31
AU763770B2 (en) 2003-07-31
IL140890A0 (en) 2002-02-10
EP1096954A2 (en) 2001-05-09
DE69920915D1 (de) 2004-11-11
CA2333578A1 (en) 2000-01-27
AU5101899A (en) 2000-02-07
KR20010071637A (ko) 2001-07-28
DE69920915T2 (de) 2006-02-16
KR100586804B1 (ko) 2006-06-07
CN1307483A (zh) 2001-08-08
CA2333578C (en) 2010-11-16
EP1096954B1 (en) 2004-10-06
ES2229745T3 (es) 2005-04-16
CN1247262C (zh) 2006-03-29
ATE278420T1 (de) 2004-10-15
WO2000003744A3 (en) 2000-04-27

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