DK1056745T3 - 6,9-Disubstituerede 2-[trans-(4-aminocyklohexyl)amino]puriner - Google Patents
6,9-Disubstituerede 2-[trans-(4-aminocyklohexyl)amino]purinerInfo
- Publication number
- DK1056745T3 DK1056745T3 DK99936074T DK99936074T DK1056745T3 DK 1056745 T3 DK1056745 T3 DK 1056745T3 DK 99936074 T DK99936074 T DK 99936074T DK 99936074 T DK99936074 T DK 99936074T DK 1056745 T3 DK1056745 T3 DK 1056745T3
- Authority
- DK
- Denmark
- Prior art keywords
- aminocyclohexyl
- purines
- disubstituted
- trans
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3238198A | 1998-02-26 | 1998-02-26 | |
| EP99936074A EP1056745B1 (en) | 1998-02-26 | 1999-02-18 | 6,9-disubstituted 2- trans-(4- aminocyclohexyl) amino]purines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1056745T3 true DK1056745T3 (da) | 2004-10-25 |
Family
ID=21864658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99936074T DK1056745T3 (da) | 1998-02-26 | 1999-02-18 | 6,9-Disubstituerede 2-[trans-(4-aminocyklohexyl)amino]puriner |
Country Status (31)
| Country | Link |
|---|---|
| EP (1) | EP1056745B1 (es) |
| JP (1) | JP2002504553A (es) |
| KR (1) | KR100568658B1 (es) |
| CN (1) | CN1128149C (es) |
| AP (1) | AP1258A (es) |
| AR (1) | AR019822A1 (es) |
| AT (1) | ATE269332T1 (es) |
| AU (1) | AU748178B2 (es) |
| BR (1) | BR9908325A (es) |
| CA (1) | CA2320448C (es) |
| CZ (1) | CZ291604B6 (es) |
| DE (1) | DE69918062T2 (es) |
| DK (1) | DK1056745T3 (es) |
| EE (1) | EE04315B1 (es) |
| ES (1) | ES2219038T3 (es) |
| HK (1) | HK1030948A1 (es) |
| HU (1) | HUP0100931A3 (es) |
| IL (2) | IL138044A0 (es) |
| NO (1) | NO20004281L (es) |
| NZ (1) | NZ506234A (es) |
| OA (1) | OA11480A (es) |
| PL (1) | PL344021A1 (es) |
| PT (1) | PT1056745E (es) |
| RU (1) | RU2191777C2 (es) |
| SI (1) | SI1056745T1 (es) |
| SK (1) | SK12912000A3 (es) |
| TR (1) | TR200002482T2 (es) |
| TW (1) | TW541308B (es) |
| UA (1) | UA62996C2 (es) |
| WO (1) | WO1999043676A2 (es) |
| ZA (1) | ZA991548B (es) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6969720B2 (en) | 1999-03-17 | 2005-11-29 | Amr Technology, Inc. | Biaryl substituted purine derivatives as potent antiproliferative agents |
| US6627633B2 (en) * | 1999-03-17 | 2003-09-30 | Albany Molecular Research, Inc. | 6-substituted biaryl purine derivatives as potent cyclin/CDK inhibitors and antiproliferative agents |
| ATE322494T1 (de) * | 2000-01-07 | 2006-04-15 | Universitaire Instelling Antwe | Purin derivate, ihre herstellung und verwendung |
| YU54202A (sh) | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
| HN2001000008A (es) | 2000-01-21 | 2003-12-11 | Inc Agouron Pharmaceuticals | Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo |
| FR2806626B1 (fr) * | 2000-03-22 | 2003-11-28 | Centre Nat Rech Scient | Utilisation de substances modulatrices de l'expression ou de la fonction d'une proteine impliquee dans le cycle cellulaire pour le traitement ou la prevention des lesions neurales aigues |
| MXPA02010222A (es) | 2000-04-18 | 2003-05-23 | Agouron Pharma | Pirazoles para inhibir proteina cinasa. |
| EP1307462A2 (en) | 2000-08-09 | 2003-05-07 | Agouron Pharmaceuticals, Inc. | Pyrazole-thiazole compounds, pharmaceutical compositions containing them, and methods of their use for inhibiting cyclin-dependent kinases |
| WO2002016326A1 (en) | 2000-08-18 | 2002-02-28 | Agouron Pharmaceuticals, Inc. | Heterocyclic-hydroxyimino-fluorenes and their use for inhibiting protein kinases |
| GB0117075D0 (en) * | 2000-10-31 | 2001-09-05 | Aventis Pharm Prod Inc | Acyl and sulfonyl derivatives of 6, 9-distributed 2-(trans-1, 4-diaminocyclohexyl)-purines and their use as antiproliferative agents |
| DK1377579T3 (da) * | 2000-10-31 | 2009-08-31 | Aventis Pharma Inc | Acyl- og sulfonylderivater af 6,9-disubstitueret-2(trans-1,4-diaminocyklohexyl)puriner og deres anvendelse som antiproliferative midler |
| US6756374B2 (en) | 2001-01-22 | 2004-06-29 | Hoffmann-La Roche Inc. | Diaminothiazoles having antiproliferative activity |
| GB2378180B8 (en) * | 2001-06-27 | 2009-10-21 | Cyclacel Ltd | New purine derivatives |
| US6667311B2 (en) | 2001-09-11 | 2003-12-23 | Albany Molecular Research, Inc. | Nitrogen substituted biaryl purine derivatives as potent antiproliferative agents |
| US6812232B2 (en) | 2001-09-11 | 2004-11-02 | Amr Technology, Inc. | Heterocycle substituted purine derivatives as potent antiproliferative agents |
| GB0219052D0 (en) | 2002-08-15 | 2002-09-25 | Cyclacel Ltd | New puring derivatives |
| GB0219054D0 (en) | 2002-08-15 | 2002-09-25 | Cyclacel Ltd | New purine derivatives |
| WO2004069233A1 (ja) * | 2003-02-04 | 2004-08-19 | Kabushiki Kaisha Yakult Honsha | 乳癌耐性蛋白阻害剤 |
| US7211576B2 (en) | 2004-04-20 | 2007-05-01 | Hoffmann-La Roche Inc. | Diaminothiazoles |
| AU2007235524B2 (en) * | 2006-03-30 | 2013-09-12 | Ptc Therapeutics, Inc. | Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith |
| MY150993A (en) * | 2007-10-05 | 2014-03-31 | Verastem Inc | Pyrimidine substituted purine derivatives |
| CN102241646B (zh) * | 2010-05-14 | 2014-04-09 | 中国人民解放军军事医学科学院毒物药物研究所 | 己烯酮类化合物及其医药用途 |
| WO2013130461A1 (en) | 2012-02-29 | 2013-09-06 | The Scripps Research Institute | Wee1 degradation inhibitors |
| EP3020829B1 (en) * | 2013-07-12 | 2021-11-17 | Kyoto University | Pharmaceutical composition capable of inhibiting abnormal splicing causative of onset or progress of a genetic disease |
| BR112017015019A2 (pt) | 2015-01-16 | 2018-01-30 | The General Hospital Corporation | compostos para melhorar a splicing de mrna |
| CN107903274A (zh) * | 2017-12-28 | 2018-04-13 | 窦玉玲 | 一种胺类化合物及其在抗肿瘤药物中的应用 |
| US20220251085A1 (en) * | 2019-07-21 | 2022-08-11 | University Of Virginia Patent Foundation | Cysteine binding compositions and methods of use thereof |
| WO2024105159A1 (en) * | 2022-11-16 | 2024-05-23 | University Of Zurich | Ligands of the m6a-rna readers |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9301000D0 (en) * | 1993-01-20 | 1993-03-10 | Glaxo Group Ltd | Chemical compounds |
| GB9414208D0 (en) * | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
| CA2234609C (en) * | 1995-11-01 | 2006-11-28 | Novartis Ag | 2-amino-6-anilino-purine derivatives and processes for their preparation |
| FR2741881B1 (fr) * | 1995-12-01 | 1999-07-30 | Centre Nat Rech Scient | Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques |
-
1999
- 1999-02-18 TR TR2000/02482T patent/TR200002482T2/xx unknown
- 1999-02-18 EE EEP200000501A patent/EE04315B1/xx not_active IP Right Cessation
- 1999-02-18 CA CA002320448A patent/CA2320448C/en not_active Expired - Fee Related
- 1999-02-18 RU RU2000124409/04A patent/RU2191777C2/ru active
- 1999-02-18 AP APAP/P/2000/001923A patent/AP1258A/en active
- 1999-02-18 WO PCT/US1999/003451 patent/WO1999043676A2/en active IP Right Grant
- 1999-02-18 BR BR9908325-6A patent/BR9908325A/pt not_active IP Right Cessation
- 1999-02-18 SK SK1291-2000A patent/SK12912000A3/sk unknown
- 1999-02-18 NZ NZ506234A patent/NZ506234A/en active IP Right Revival
- 1999-02-18 EP EP99936074A patent/EP1056745B1/en not_active Expired - Lifetime
- 1999-02-18 AU AU32990/99A patent/AU748178B2/en not_active Ceased
- 1999-02-18 PL PL99344021A patent/PL344021A1/xx unknown
- 1999-02-18 SI SI9930621T patent/SI1056745T1/xx unknown
- 1999-02-18 DE DE69918062T patent/DE69918062T2/de not_active Expired - Fee Related
- 1999-02-18 HU HU0100931A patent/HUP0100931A3/hu unknown
- 1999-02-18 IL IL13804499A patent/IL138044A0/xx active IP Right Grant
- 1999-02-18 CN CN99803395A patent/CN1128149C/zh not_active Expired - Fee Related
- 1999-02-18 KR KR1020007009421A patent/KR100568658B1/ko not_active IP Right Cessation
- 1999-02-18 AT AT99936074T patent/ATE269332T1/de not_active IP Right Cessation
- 1999-02-18 UA UA2000095500A patent/UA62996C2/uk unknown
- 1999-02-18 PT PT99936074T patent/PT1056745E/pt unknown
- 1999-02-18 CZ CZ20003106A patent/CZ291604B6/cs not_active IP Right Cessation
- 1999-02-18 JP JP2000533431A patent/JP2002504553A/ja active Pending
- 1999-02-18 ES ES99936074T patent/ES2219038T3/es not_active Expired - Lifetime
- 1999-02-18 DK DK99936074T patent/DK1056745T3/da active
- 1999-02-24 TW TW088102781A patent/TW541308B/zh not_active IP Right Cessation
- 1999-02-25 AR ARP990100782A patent/AR019822A1/es active IP Right Grant
- 1999-02-25 ZA ZA9901548A patent/ZA991548B/xx unknown
-
2000
- 2000-08-23 IL IL138044A patent/IL138044A/en not_active IP Right Cessation
- 2000-08-25 OA OA1200000234A patent/OA11480A/en unknown
- 2000-08-25 NO NO20004281A patent/NO20004281L/no not_active Application Discontinuation
-
2001
- 2001-03-16 HK HK01101931A patent/HK1030948A1/xx not_active IP Right Cessation
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