DK1027345T3 - Syntetiske fremgangsmåder for polyphenoler - Google Patents

Syntetiske fremgangsmåder for polyphenoler

Info

Publication number
DK1027345T3
DK1027345T3 DK98953371T DK98953371T DK1027345T3 DK 1027345 T3 DK1027345 T3 DK 1027345T3 DK 98953371 T DK98953371 T DK 98953371T DK 98953371 T DK98953371 T DK 98953371T DK 1027345 T3 DK1027345 T3 DK 1027345T3
Authority
DK
Denmark
Prior art keywords
polyphenol
protected
monomeric units
polyphenols
synthetic methods
Prior art date
Application number
DK98953371T
Other languages
Danish (da)
English (en)
Inventor
Leo J Romanczyk Jr
Alan P Kozikowski
Werner Tueckmantel
Marc E Lippman
Original Assignee
Mars Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mars Inc filed Critical Mars Inc
Application granted granted Critical
Publication of DK1027345T3 publication Critical patent/DK1027345T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK98953371T 1997-10-09 1998-10-09 Syntetiske fremgangsmåder for polyphenoler DK1027345T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/948,226 US6207842B1 (en) 1997-10-09 1997-10-09 Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
PCT/US1998/021392 WO1999019319A1 (en) 1997-10-09 1998-10-09 Synthetic methods for polyphenols

Publications (1)

Publication Number Publication Date
DK1027345T3 true DK1027345T3 (da) 2003-06-10

Family

ID=25487506

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98953371T DK1027345T3 (da) 1997-10-09 1998-10-09 Syntetiske fremgangsmåder for polyphenoler

Country Status (13)

Country Link
US (6) US6207842B1 (xx)
EP (1) EP1027345B1 (xx)
JP (1) JP2001519426A (xx)
KR (1) KR100560463B1 (xx)
CN (2) CN101066962A (xx)
AT (1) ATE232857T1 (xx)
AU (1) AU760031B2 (xx)
CA (1) CA2306851A1 (xx)
DE (1) DE69811526T2 (xx)
DK (1) DK1027345T3 (xx)
ES (1) ES2189260T3 (xx)
IL (1) IL135344A (xx)
WO (1) WO1999019319A1 (xx)

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Also Published As

Publication number Publication date
JP2001519426A (ja) 2001-10-23
ATE232857T1 (de) 2003-03-15
CN100341867C (zh) 2007-10-10
CN101066962A (zh) 2007-11-07
EP1027345B1 (en) 2003-02-19
US20040235941A1 (en) 2004-11-25
US20030176620A1 (en) 2003-09-18
ES2189260T3 (es) 2003-07-01
US6849746B2 (en) 2005-02-01
US7268240B2 (en) 2007-09-11
AU760031B2 (en) 2003-05-08
DE69811526D1 (en) 2003-03-27
KR20010030986A (ko) 2001-04-16
US6528664B2 (en) 2003-03-04
IL135344A (en) 2005-11-20
IL135344A0 (en) 2001-05-20
AU1076699A (en) 1999-05-03
CN1302295A (zh) 2001-07-04
WO1999019319A1 (en) 1999-04-22
US20040236123A1 (en) 2004-11-25
US20020128493A1 (en) 2002-09-12
US6207842B1 (en) 2001-03-27
US6420572B1 (en) 2002-07-16
KR100560463B1 (ko) 2006-03-13
EP1027345A1 (en) 2000-08-16
CA2306851A1 (en) 1999-04-22
DE69811526T2 (de) 2003-11-06

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