DK10189D0 - Fremgangsmaade til indvinding af renset, oxideret, renatureret interleukin-2 fra mikroorganismer - Google Patents

Fremgangsmaade til indvinding af renset, oxideret, renatureret interleukin-2 fra mikroorganismer

Info

Publication number
DK10189D0
DK10189D0 DK010189A DK10189A DK10189D0 DK 10189 D0 DK10189 D0 DK 10189D0 DK 010189 A DK010189 A DK 010189A DK 10189 A DK10189 A DK 10189A DK 10189 D0 DK10189 D0 DK 10189D0
Authority
DK
Denmark
Prior art keywords
oxidized
guanidine hydrochloride
renated
oxidated
interleukin
Prior art date
Application number
DK010189A
Other languages
English (en)
Other versions
DK10189A (da
Inventor
Sidney N Wolfe
Amy Lim
Glenn Dorin
Flint Smith
John T Davis
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of DK10189A publication Critical patent/DK10189A/da
Publication of DK10189D0 publication Critical patent/DK10189D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK010189A 1987-05-11 1989-01-11 Fremgangsmaade til indvinding af renset, oxideret, renatureret interleukin-2 fra mikroorganismer DK10189D0 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4840887A 1987-05-11 1987-05-11
US16714488A 1988-03-25 1988-03-25
PCT/US1988/001043 WO1988008849A1 (en) 1987-05-11 1988-03-31 Process for recovering purified, oxidized, renatured recombinant interleukin-2 from microorganisms

Publications (2)

Publication Number Publication Date
DK10189A DK10189A (da) 1989-01-11
DK10189D0 true DK10189D0 (da) 1989-01-11

Family

ID=26726091

Family Applications (1)

Application Number Title Priority Date Filing Date
DK010189A DK10189D0 (da) 1987-05-11 1989-01-11 Fremgangsmaade til indvinding af renset, oxideret, renatureret interleukin-2 fra mikroorganismer

Country Status (9)

Country Link
EP (1) EP0368857B1 (da)
JP (1) JP2955294B2 (da)
AT (1) ATE156491T1 (da)
AU (1) AU622860B2 (da)
DE (1) DE3855986T2 (da)
DK (1) DK10189D0 (da)
IL (1) IL86326A (da)
NO (1) NO176797C (da)
WO (1) WO1988008849A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
EP0337243A1 (en) * 1988-04-14 1989-10-18 F. Hoffmann-La Roche Ag Process for purifying recombinant human interleukin-2
DK580789D0 (da) * 1989-11-20 1989-11-20 Novo Nordisk As Fremgangsmaade til oprensning af polypeptider
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
WO1992012429A1 (fr) * 1991-01-10 1992-07-23 Teijin Limited Analyse a sensibilite elevee de facteur tissulaire et kit utilise a cet effet
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
JPH08502661A (ja) * 1993-08-04 1996-03-26 チバ−ガイギー アクチェンゲゼルシャフト 高分子量デスルファトヒルジン
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
TW517059B (en) 1994-07-25 2003-01-11 Ciba Geigy Ag New process for the production of biologically active protein
JPH11509551A (ja) * 1995-07-21 1999-08-24 アムジエン・インコーポレーテツド 蛋白質を塩から分離することのできる連続静止相を用いてバッファー交換により蛋白質を巻き戻す方法
WO2003097669A2 (en) * 2002-05-17 2003-11-27 Københavns Universitet Method for purifying denatured proteins having a desired disulfide bond configuration

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79124B (da) * 1982-12-22 1984-10-02 Genentech Inc
US4530787A (en) * 1984-03-28 1985-07-23 Cetus Corporation Controlled oxidation of microbially produced cysteine-containing proteins
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
US4572798A (en) * 1984-12-06 1986-02-25 Cetus Corporation Method for promoting disulfide bond formation in recombinant proteins
JPH0640832B2 (ja) * 1985-05-10 1994-06-01 味の素株式会社 インタ−ロイキン２ポリペプチドの回収方法
US4748234A (en) * 1985-06-26 1988-05-31 Cetus Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts
US4656255A (en) * 1985-09-09 1987-04-07 International Minerals & Chemical Corp. Protein recovery
US4801686A (en) * 1986-09-04 1989-01-31 Immunex Corporation Purification of recombinant interleukin-1
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2

Also Published As

Publication number Publication date
WO1988008849A1 (en) 1988-11-17
JP2955294B2 (ja) 1999-10-04
NO885678L (no) 1988-12-21
EP0368857A1 (en) 1990-05-23
AU622860B2 (en) 1992-04-30
NO176797B (no) 1995-02-20
DK10189A (da) 1989-01-11
AU1627988A (en) 1988-12-06
IL86326A0 (en) 1988-11-15
IL86326A (en) 1997-02-18
JPH02503384A (ja) 1990-10-18
DE3855986T2 (de) 1998-02-05
NO885678D0 (no) 1988-12-21
NO176797C (no) 1995-05-31
EP0368857B1 (en) 1997-08-06
DE3855986D1 (de) 1997-09-11
ATE156491T1 (de) 1997-08-15

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