ATE43639T1 - Verfahren zur entfernung von verunreinigungen aus leukozytinterferon-zubereitungen und das so hergestellte gereinigte leukozytinterferon. - Google Patents

Verfahren zur entfernung von verunreinigungen aus leukozytinterferon-zubereitungen und das so hergestellte gereinigte leukozytinterferon.

Info

Publication number
ATE43639T1
ATE43639T1 AT83306614T AT83306614T ATE43639T1 AT E43639 T1 ATE43639 T1 AT E43639T1 AT 83306614 T AT83306614 T AT 83306614T AT 83306614 T AT83306614 T AT 83306614T AT E43639 T1 ATE43639 T1 AT E43639T1
Authority
AT
Austria
Prior art keywords
interferon
leukocytin
impurities
purified
removal
Prior art date
Application number
AT83306614T
Other languages
English (en)
Inventor
Paul D Johnston
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE43639T1 publication Critical patent/ATE43639T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT83306614T 1982-11-01 1983-10-31 Verfahren zur entfernung von verunreinigungen aus leukozytinterferon-zubereitungen und das so hergestellte gereinigte leukozytinterferon. ATE43639T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/438,129 US4534906A (en) 1982-11-01 1982-11-01 Removal of impurities from human leukocyte interferon preparations
EP83306614A EP0108585B1 (de) 1982-11-01 1983-10-31 Verfahren zur Entfernung von Verunreinigungen aus Leukozytinterferon-Zubereitungen und das so hergestellte gereinigte Leukozytinterferon

Publications (1)

Publication Number Publication Date
ATE43639T1 true ATE43639T1 (de) 1989-06-15

Family

ID=23739353

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83306614T ATE43639T1 (de) 1982-11-01 1983-10-31 Verfahren zur entfernung von verunreinigungen aus leukozytinterferon-zubereitungen und das so hergestellte gereinigte leukozytinterferon.

Country Status (10)

Country Link
US (1) US4534906A (de)
EP (1) EP0108585B1 (de)
JP (1) JPS5998096A (de)
AT (1) ATE43639T1 (de)
AU (1) AU575304B2 (de)
CA (1) CA1211711A (de)
DE (1) DE3379964D1 (de)
DK (1) DK160617C (de)
IE (1) IE56181B1 (de)
ZA (1) ZA838109B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8401911A (nl) * 1984-06-15 1986-01-02 Stichting Rega V Z W Antiviraal proteine, werkwijze voor het produceren daarvan, en farmaceutische preparaten die dit proteine bevatten.
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
US4961969A (en) * 1987-05-11 1990-10-09 Cetus Corporation Process for recovering microbially produced interferon-β
ATE78698T1 (de) * 1987-10-06 1992-08-15 Interferon Sciences Inc Reinigung von monomerem interferon.
US4765903A (en) * 1987-10-06 1988-08-23 Interferon Sciences, Inc. Purification of monomeric interferon
US5182369A (en) * 1990-02-28 1993-01-26 Monsanto Company Method for purifying somatotropin monomers
AU2592395A (en) * 1994-05-19 1995-12-18 Monsanto Company Method for purifying somatotropin monomers
US6281337B1 (en) 1998-11-12 2001-08-28 Schering Corporation Methods for conversion of protein isoforms
EP2236156A3 (de) * 2001-01-09 2011-01-05 Baylor Research Institute Verfahren zur Behandlung und Diagnose von Psoriasis
ITBO20010426A1 (it) * 2001-07-06 2003-01-06 Alfa Wassermann Spa Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico
KR100531670B1 (ko) * 2003-12-03 2005-11-28 씨제이 주식회사 인체 인터페론 알파의 제조방법
EP2195338B1 (de) 2007-10-01 2013-12-25 Pharmaessentia Corp. N-terminal modifiziertes interferon-alpha
CA2746502A1 (en) 2008-12-23 2010-07-01 Xiaoyu Yang Purification of recombinantly produced interferon
JP6431851B2 (ja) * 2013-12-25 2018-11-28 株式会社海月研究所 水不溶性高分子化合物の分解物の連続的製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN150740B (de) * 1978-11-24 1982-12-04 Hoffmann La Roche
ZA796175B (en) * 1978-11-24 1980-11-26 Hoffmann La Roche Purified proteins and process therefor
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
AU8736282A (en) * 1981-08-13 1983-02-22 American National Red Cross, The Filtration method for cell produced antiviral substances

Also Published As

Publication number Publication date
DK160617B (da) 1991-04-02
JPH0434560B2 (de) 1992-06-08
IE832542L (en) 1984-05-01
DK498183A (da) 1984-05-02
AU575304B2 (en) 1988-07-28
EP0108585B1 (de) 1989-05-31
EP0108585A3 (en) 1985-07-31
JPS5998096A (ja) 1984-06-06
DE3379964D1 (en) 1989-07-06
AU2085583A (en) 1984-05-10
US4534906A (en) 1985-08-13
IE56181B1 (en) 1991-05-08
DK498183D0 (da) 1983-10-31
CA1211711A (en) 1986-09-23
DK160617C (da) 1991-09-16
ZA838109B (en) 1984-09-26
EP0108585A2 (de) 1984-05-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time