CA1211711A - Removal of impurities from human leukocyte interferon preparations - Google Patents

Removal of impurities from human leukocyte interferon preparations

Info

Publication number
CA1211711A
CA1211711A CA000440065A CA440065A CA1211711A CA 1211711 A CA1211711 A CA 1211711A CA 000440065 A CA000440065 A CA 000440065A CA 440065 A CA440065 A CA 440065A CA 1211711 A CA1211711 A CA 1211711A
Authority
CA
Canada
Prior art keywords
ifn
alpha
huifn
native
oligomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000440065A
Other languages
English (en)
French (fr)
Inventor
Paul D. Johnston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of CA1211711A publication Critical patent/CA1211711A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA000440065A 1982-11-01 1983-10-31 Removal of impurities from human leukocyte interferon preparations Expired CA1211711A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/438,129 US4534906A (en) 1982-11-01 1982-11-01 Removal of impurities from human leukocyte interferon preparations
US438,129 1982-11-01

Publications (1)

Publication Number Publication Date
CA1211711A true CA1211711A (en) 1986-09-23

Family

ID=23739353

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000440065A Expired CA1211711A (en) 1982-11-01 1983-10-31 Removal of impurities from human leukocyte interferon preparations

Country Status (10)

Country Link
US (1) US4534906A (de)
EP (1) EP0108585B1 (de)
JP (1) JPS5998096A (de)
AT (1) ATE43639T1 (de)
AU (1) AU575304B2 (de)
CA (1) CA1211711A (de)
DE (1) DE3379964D1 (de)
DK (1) DK160617C (de)
IE (1) IE56181B1 (de)
ZA (1) ZA838109B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8401911A (nl) * 1984-06-15 1986-01-02 Stichting Rega V Z W Antiviraal proteine, werkwijze voor het produceren daarvan, en farmaceutische preparaten die dit proteine bevatten.
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
US4961969A (en) * 1987-05-11 1990-10-09 Cetus Corporation Process for recovering microbially produced interferon-β
JPH03500410A (ja) * 1987-10-06 1991-01-31 インターフェロン　サイエンシズ，インコーポレイティド モノマーインターフェロンの精製
US4765903A (en) * 1987-10-06 1988-08-23 Interferon Sciences, Inc. Purification of monomeric interferon
US5182369A (en) * 1990-02-28 1993-01-26 Monsanto Company Method for purifying somatotropin monomers
AU2592395A (en) * 1994-05-19 1995-12-18 Monsanto Company Method for purifying somatotropin monomers
US6281337B1 (en) 1998-11-12 2001-08-28 Schering Corporation Methods for conversion of protein isoforms
DE60239522D1 (de) * 2001-01-09 2011-05-05 Baylor Res Inst Dallas Verfahren zur behandlung von autoimmunerkrankungen bei einem probanden und diagnostische in-vitro-assays
ITBO20010426A1 (it) 2001-07-06 2003-01-06 Alfa Wassermann Spa Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico
KR100531670B1 (ko) * 2003-12-03 2005-11-28 씨제이 주식회사 인체 인터페론 알파의 제조방법
EP2195338B1 (de) 2007-10-01 2013-12-25 Pharmaessentia Corp. N-terminal modifiziertes interferon-alpha
US20110257368A1 (en) 2008-12-23 2011-10-20 Schering Corporation Purification of recombinantly produced interferon
WO2015098634A1 (ja) * 2013-12-25 2015-07-02 株式会社海月研究所 水不溶性高分子化合物の分解物の連続的製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA796175B (en) * 1978-11-24 1980-11-26 Hoffmann La Roche Purified proteins and process therefor
IN150740B (de) * 1978-11-24 1982-12-04 Hoffmann La Roche
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
AU8736282A (en) * 1981-08-13 1983-02-22 American National Red Cross, The Filtration method for cell produced antiviral substances

Also Published As

Publication number Publication date
JPH0434560B2 (de) 1992-06-08
AU2085583A (en) 1984-05-10
US4534906A (en) 1985-08-13
IE56181B1 (en) 1991-05-08
DE3379964D1 (en) 1989-07-06
DK498183D0 (da) 1983-10-31
AU575304B2 (en) 1988-07-28
ATE43639T1 (de) 1989-06-15
DK160617C (da) 1991-09-16
DK498183A (da) 1984-05-02
JPS5998096A (ja) 1984-06-06
ZA838109B (en) 1984-09-26
EP0108585A2 (de) 1984-05-16
EP0108585B1 (de) 1989-05-31
DK160617B (da) 1991-04-02
EP0108585A3 (en) 1985-07-31
IE832542L (en) 1984-05-01

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Legal Events

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