DK0951465T3 - Alpha-aminosyreamider, fremstilling deraf og den terapeutiske anvendelse deraf - Google Patents

Alpha-aminosyreamider, fremstilling deraf og den terapeutiske anvendelse deraf

Info

Publication number
DK0951465T3
DK0951465T3 DK97933680T DK97933680T DK0951465T3 DK 0951465 T3 DK0951465 T3 DK 0951465T3 DK 97933680 T DK97933680 T DK 97933680T DK 97933680 T DK97933680 T DK 97933680T DK 0951465 T3 DK0951465 T3 DK 0951465T3
Authority
DK
Denmark
Prior art keywords
alpha
preparation
amino acid
acid amides
therapeutic use
Prior art date
Application number
DK97933680T
Other languages
Danish (da)
English (en)
Inventor
Paolo Chiesi
Paolo Ventura
Maurizio Delcanale
Renato De Fanti
Elisabetta Armani
Gino Villetti
Claudio Pietra
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of DK0951465T3 publication Critical patent/DK0951465T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK97933680T 1996-07-23 1997-07-15 Alpha-aminosyreamider, fremstilling deraf og den terapeutiske anvendelse deraf DK0951465T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI001544A IT1283489B1 (it) 1996-07-23 1996-07-23 Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
PCT/EP1997/003773 WO1998003472A1 (en) 1996-07-23 1997-07-15 Alpha-amino acid amides, preparation thereof and the therapeutical use thereof

Publications (1)

Publication Number Publication Date
DK0951465T3 true DK0951465T3 (da) 2003-08-11

Family

ID=11374651

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97933680T DK0951465T3 (da) 1996-07-23 1997-07-15 Alpha-aminosyreamider, fremstilling deraf og den terapeutiske anvendelse deraf

Country Status (26)

Country Link
US (1) US6114391A (id)
EP (1) EP0951465B1 (id)
JP (1) JP4542208B2 (id)
CN (1) CN1211351C (id)
AR (1) AR007963A1 (id)
AT (1) ATE237584T1 (id)
AU (1) AU729176B2 (id)
CA (1) CA2261259C (id)
CZ (1) CZ295824B6 (id)
DE (1) DE69721052T2 (id)
DK (1) DK0951465T3 (id)
ES (1) ES2195158T3 (id)
HU (1) HU225623B1 (id)
ID (1) ID17999A (id)
IL (1) IL128020A (id)
IT (1) IT1283489B1 (id)
MY (1) MY118244A (id)
NO (1) NO326826B3 (id)
NZ (1) NZ333869A (id)
PT (1) PT951465E (id)
RU (1) RU2174511C2 (id)
SI (1) SI0951465T1 (id)
TR (1) TR199900087T2 (id)
TW (1) TW557291B (id)
WO (1) WO1998003472A1 (id)
ZA (1) ZA976479B (id)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672746A (en) 1994-08-30 1997-09-30 American Biogenetic Sciences, Inc. Antiproliferative and neurotrophic molecules
PL345364A1 (en) 1998-06-22 2001-12-17 American Biogenetic Sciences The use of valproic acid analog for the treatment and prevention of migraine and affective illness
US20030035784A1 (en) 2001-03-05 2003-02-20 Kao Corporation Hair cosmetic, aminocarboxylic acid amide and method for producing the same
ES2270947T3 (es) * 2001-12-21 2007-04-16 Chiesi Farmaceutici S.P.A. Derivados de 2-indanilamino para la terapia de dolor cronico, agudo o inflamatorio.
FR2843590B1 (fr) * 2002-08-14 2007-10-05 Prestwick Scient Capital Inc Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
US20040082543A1 (en) * 2002-10-29 2004-04-29 Pharmacia Corporation Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
WO2006016219A2 (en) * 2004-08-03 2006-02-16 Chiesi Farmaceutici S.P.A. Derivatives of 1-phenylalkanecarboxylic acids for the treatment of neurodegenerative diseases
US9475757B2 (en) 2013-05-03 2016-10-25 Council Of Scientific & Industrial Research Synthesis of anti-Parkinson agent
CN105646252A (zh) * 2016-02-25 2016-06-08 吉尔生化（上海）有限公司 一种丝氨酸酰胺盐酸盐的合成方法
CN114051496B (zh) * 2019-06-25 2023-08-04 阿米蒂比奥有限公司 将联苯基引入新型氨基烷酸的衍生物化合物及包含其的抗真菌药学组合物
CA3218884A1 (en) * 2021-05-11 2022-11-17 David Nutt Therapeutic aminoindane compounds and compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3050800C2 (id) * 1979-03-22 1989-06-22 Continental Pharma Inc., Bruessel/Bruxelles, Be
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
EP0333154B1 (en) * 1988-03-16 1997-07-16 Eisai Co., Ltd. Process for the preparation of cephem derivatives
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5198547A (en) * 1992-03-16 1993-03-30 South Alabama Medical Science Foundation, Usa Process for N5-formylating tetrahydropteridines
GB9306899D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
GB9306886D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
US5332840A (en) * 1993-05-27 1994-07-26 Bristol-Myers Squibb Company Method for preparing a benzaldehyde intermediate

Also Published As

Publication number Publication date
JP4542208B2 (ja) 2010-09-08
NO990300L (no) 1999-01-22
NO326826B3 (no) 2010-06-07
CZ295824B6 (cs) 2005-11-16
CN1211351C (zh) 2005-07-20
NO326826B1 (no) 2009-02-23
HU225623B1 (en) 2007-05-02
PT951465E (pt) 2003-08-29
ITMI961544A1 (it) 1998-01-23
EP0951465B1 (en) 2003-04-16
AR007963A1 (es) 1999-11-24
AU3695297A (en) 1998-02-10
IT1283489B1 (it) 1998-04-21
ES2195158T3 (es) 2003-12-01
CZ18299A3 (cs) 1999-06-16
CA2261259A1 (en) 1998-01-29
MY118244A (en) 2004-09-30
IL128020A (en) 2002-04-21
ATE237584T1 (de) 2003-05-15
US6114391A (en) 2000-09-05
TR199900087T2 (xx) 1999-03-22
IL128020A0 (en) 1999-11-30
SI0951465T1 (en) 2003-08-31
EP0951465A1 (en) 1999-10-27
JP2001506577A (ja) 2001-05-22
AU729176B2 (en) 2001-01-25
CA2261259C (en) 2006-10-03
DE69721052T2 (de) 2004-02-05
RU2174511C2 (ru) 2001-10-10
NZ333869A (en) 2000-05-26
ITMI961544A0 (id) 1996-07-23
WO1998003472A1 (en) 1998-01-29
TW557291B (en) 2003-10-11
ID17999A (id) 1998-02-19
ZA976479B (en) 1998-03-02
HUP9902992A3 (en) 2004-04-28
DE69721052D1 (de) 2003-05-22
NO990300D0 (no) 1999-01-22
CN1225625A (zh) 1999-08-11

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