NO975513D0 - 3-hydroksypyridin-2-karboksylsyreamidester, fremstilling og anvendelse som legemiddel - Google Patents
3-hydroksypyridin-2-karboksylsyreamidester, fremstilling og anvendelse som legemiddelInfo
- Publication number
- NO975513D0 NO975513D0 NO975513A NO975513A NO975513D0 NO 975513 D0 NO975513 D0 NO 975513D0 NO 975513 A NO975513 A NO 975513A NO 975513 A NO975513 A NO 975513A NO 975513 D0 NO975513 D0 NO 975513D0
- Authority
- NO
- Norway
- Prior art keywords
- hydroxypyridine
- drug
- preparation
- carboxylic acid
- acid amide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19650215A DE19650215A1 (de) | 1996-12-04 | 1996-12-04 | 3-Hydroxypyridin-2-carbonsäureamidester, ihre Herstellung und ihre Verwendung als Arzneimittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO975513D0 true NO975513D0 (no) | 1997-12-01 |
| NO975513L NO975513L (no) | 1998-06-05 |
| NO309717B1 NO309717B1 (no) | 2001-03-19 |
Family
ID=7813570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO975513A NO309717B1 (no) | 1996-12-04 | 1997-12-01 | 3-hydroksypyridin-2-karboksylsyreamidester, fremstilling og anvendelse i legemiddel |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6020350A (no) |
| EP (1) | EP0846685B1 (no) |
| JP (1) | JPH10168062A (no) |
| KR (1) | KR19980063725A (no) |
| CN (1) | CN1184104A (no) |
| AR (1) | AR010328A1 (no) |
| AT (1) | ATE214371T1 (no) |
| AU (1) | AU743750B2 (no) |
| BR (1) | BR9706129A (no) |
| CA (1) | CA2223366A1 (no) |
| CZ (1) | CZ383297A3 (no) |
| DE (2) | DE19650215A1 (no) |
| HU (1) | HUP9702345A2 (no) |
| NO (1) | NO309717B1 (no) |
| NZ (1) | NZ329299A (no) |
| PL (1) | PL323517A1 (no) |
| SG (1) | SG65705A1 (no) |
| TR (1) | TR199701490A2 (no) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306839B1 (en) | 1998-09-16 | 2001-10-23 | Dow Agrosciences Llc | 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring |
| PL206415B1 (pl) | 1999-07-20 | 2010-08-31 | Dow Agrosciences Llc | Heterocykliczny amid aromatyczny, kompozycja grzybobójcza heterocyklicznego amidu aromatycznego oraz sposób zwalczania lub zapobiegania zakażeniom grzybami |
| FR2803592A1 (fr) * | 2000-01-06 | 2001-07-13 | Aventis Cropscience Sa | Nouveaux derives de l'acide 3-hydroxypicolinique, leur procede de preparation et compositions fongicides les contenant. |
| EP2295060B1 (en) | 2001-12-06 | 2018-10-31 | Fibrogen, Inc. | Treatment or prevention of ischemic or hypoxic conditions |
| ES2414706T3 (es) | 2001-12-06 | 2013-07-22 | Fibrogen, Inc. | Métodos para aumentar la eritropoyetina endógena |
| US8318703B2 (en) | 2001-12-06 | 2012-11-27 | Fibrogen, Inc. | Methods for improving kidney function |
| US7618940B2 (en) | 2002-12-06 | 2009-11-17 | Fibrogen, Inc. | Fat regulation |
| US8124582B2 (en) | 2002-12-06 | 2012-02-28 | Fibrogen, Inc. | Treatment of diabetes |
| US8614204B2 (en) * | 2003-06-06 | 2013-12-24 | Fibrogen, Inc. | Enhanced erythropoiesis and iron metabolism |
| WO2006138511A2 (en) | 2005-06-15 | 2006-12-28 | Fibrogen, Inc. | Use of hif 1alfa modulators for treatment of cancer |
| US7745461B1 (en) | 2006-02-27 | 2010-06-29 | Alcon Research, Ltd. | Method of treating dry eye disorders |
| WO2007101204A1 (en) * | 2006-02-27 | 2007-09-07 | Alcon Research, Ltd. | Method of treating glaucoma |
| US7588924B2 (en) * | 2006-03-07 | 2009-09-15 | Procter & Gamble Company | Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase |
| KR100934674B1 (ko) * | 2006-03-30 | 2009-12-31 | 엘지전자 주식회사 | 비디오 신호를 디코딩/인코딩하기 위한 방법 및 장치 |
| EP3026044B8 (en) | 2006-06-26 | 2018-12-19 | Akebia Therapeutics, Inc. | Prolyl hydroxylase inhibitors and methods of use |
| WO2009002533A1 (en) * | 2007-06-27 | 2008-12-31 | The Brigham And Women's Hospital, Inc. | Inflammatory bowel disease therapies |
| EP2496084B1 (en) | 2009-11-06 | 2015-06-10 | Aerpio Therapeutics Inc. | Compositions and methods for treating colitis |
| CA2837560C (en) | 2011-06-06 | 2017-02-14 | Akebia Therapeutics Inc. | Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer |
| NO2686520T3 (no) | 2011-06-06 | 2018-03-17 | ||
| CN114404414A (zh) | 2013-06-13 | 2022-04-29 | 阿克比治疗有限公司 | 用于治疗贫血症的组合物和方法 |
| TWI665190B (zh) | 2013-11-15 | 2019-07-11 | 阿克比治療有限公司 | ｛［５－（３－氯苯基）－３－羥基吡啶－２－羰基］胺基｝乙酸之固體型式，其組合物及用途 |
| CN106132201A (zh) * | 2014-01-23 | 2016-11-16 | 阿克比治疗有限公司 | 用于治疗眼部疾病的组合物和方法 |
| US10150734B2 (en) | 2015-01-23 | 2018-12-11 | Akebia Therapeutics, Inc. | Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof |
| CN106146395B (zh) * | 2015-03-27 | 2019-01-01 | 沈阳三生制药有限责任公司 | 3-羟基吡啶化合物、其制备方法及其制药用途 |
| BR112017021097B1 (pt) | 2015-04-01 | 2024-01-02 | Akebia Therapeutics, Inc | Formulação de dosagem oral e seu uso |
| KR102473897B1 (ko) * | 2015-05-28 | 2022-12-06 | 니뽄 다바코 산교 가부시키가이샤 | 당뇨병성 신증을 치료 또는 예방하는 방법 |
| TW202406895A (zh) | 2018-05-09 | 2024-02-16 | 美商阿克比治療有限公司 | 用於製備2-[[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基]乙酸之方法 |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
| IT201900021960A1 (it) * | 2019-11-22 | 2021-05-22 | Isagro Spa | Composti ad attività fungicida, loro composizioni agronomiche e relativo metodo di preparazione |
| CN112979541B (zh) * | 2019-12-17 | 2022-11-11 | 浙江大学 | 一种基于n-(3-羟基吡啶-2-羰基)甘氨酸的抗肿瘤药物增敏剂及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4015255A1 (de) * | 1990-05-12 | 1991-11-14 | Hoechst Ag | Oxalyl-aminosaeurederivate, verfahren zu ihrer herstellung und ihrer verwendung als arzneimittel zur inhibierung der prolyl-hydroxylase |
| NZ270267A (en) * | 1993-12-30 | 1997-03-24 | Hoechst Ag | 3-hydroxypyridin-2yl (and -quinolin-2-yl) carboxamide derivatives and pharmaceutical compositions |
| IL135495A (en) * | 1995-09-28 | 2002-12-01 | Hoechst Ag | Intermediate compounds for the preparation of quinoline-converted amines - 2 - carboxylic acid |
-
1996
- 1996-12-04 DE DE19650215A patent/DE19650215A1/de not_active Withdrawn
-
1997
- 1997-11-24 DE DE59706602T patent/DE59706602D1/de not_active Expired - Lifetime
- 1997-11-24 EP EP97120537A patent/EP0846685B1/de not_active Expired - Lifetime
- 1997-11-24 AT AT97120537T patent/ATE214371T1/de not_active IP Right Cessation
- 1997-12-01 NO NO975513A patent/NO309717B1/no not_active IP Right Cessation
- 1997-12-02 AR ARP970105663A patent/AR010328A1/es unknown
- 1997-12-02 AU AU46792/97A patent/AU743750B2/en not_active Ceased
- 1997-12-02 CZ CZ973832A patent/CZ383297A3/cs unknown
- 1997-12-02 NZ NZ329299A patent/NZ329299A/en unknown
- 1997-12-02 TR TR97/01490A patent/TR199701490A2/xx unknown
- 1997-12-03 HU HU9702345A patent/HUP9702345A2/hu unknown
- 1997-12-03 CA CA002223366A patent/CA2223366A1/en not_active Abandoned
- 1997-12-03 SG SG1997004280A patent/SG65705A1/en unknown
- 1997-12-03 CN CN97125404A patent/CN1184104A/zh active Pending
- 1997-12-03 BR BR9706129A patent/BR9706129A/pt unknown
- 1997-12-03 KR KR1019970065494A patent/KR19980063725A/ko not_active Application Discontinuation
- 1997-12-04 US US08/985,266 patent/US6020350A/en not_active Expired - Fee Related
- 1997-12-04 JP JP9334148A patent/JPH10168062A/ja active Pending
- 1997-12-04 PL PL97323517A patent/PL323517A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU743750B2 (en) | 2002-02-07 |
| BR9706129A (pt) | 1999-05-18 |
| JPH10168062A (ja) | 1998-06-23 |
| KR19980063725A (ko) | 1998-10-07 |
| EP0846685A1 (de) | 1998-06-10 |
| US6020350A (en) | 2000-02-01 |
| CN1184104A (zh) | 1998-06-10 |
| EP0846685B1 (de) | 2002-03-13 |
| HU9702345D0 (en) | 1998-03-02 |
| MX9709438A (es) | 1998-06-30 |
| NO309717B1 (no) | 2001-03-19 |
| TR199701490A2 (xx) | 1998-06-22 |
| CA2223366A1 (en) | 1998-06-04 |
| DE59706602D1 (de) | 2002-04-18 |
| AR010328A1 (es) | 2000-06-07 |
| HUP9702345A2 (hu) | 2002-11-28 |
| AU4679297A (en) | 1998-06-11 |
| NO975513L (no) | 1998-06-05 |
| ATE214371T1 (de) | 2002-03-15 |
| CZ383297A3 (cs) | 1998-06-17 |
| NZ329299A (en) | 1998-11-25 |
| DE19650215A1 (de) | 1998-06-10 |
| PL323517A1 (en) | 1998-06-08 |
| SG65705A1 (en) | 1999-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JUNE 2003 |