SG65705A1 - 3-Hydroxypiridine-2-carboxamidoesters their perparation and their use as pharmaceuticals - Google Patents
3-Hydroxypiridine-2-carboxamidoesters their perparation and their use as pharmaceuticalsInfo
- Publication number
- SG65705A1 SG65705A1 SG1997004280A SG1997004280A SG65705A1 SG 65705 A1 SG65705 A1 SG 65705A1 SG 1997004280 A SG1997004280 A SG 1997004280A SG 1997004280 A SG1997004280 A SG 1997004280A SG 65705 A1 SG65705 A1 SG 65705A1
- Authority
- SG
- Singapore
- Prior art keywords
- carboxamidoesters
- hydroxypiridine
- perparation
- pharmaceuticals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19650215A DE19650215A1 (de) | 1996-12-04 | 1996-12-04 | 3-Hydroxypyridin-2-carbonsäureamidester, ihre Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG65705A1 true SG65705A1 (en) | 1999-06-22 |
Family
ID=7813570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG1997004280A SG65705A1 (en) | 1996-12-04 | 1997-12-03 | 3-Hydroxypiridine-2-carboxamidoesters their perparation and their use as pharmaceuticals |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6020350A (no) |
| EP (1) | EP0846685B1 (no) |
| JP (1) | JPH10168062A (no) |
| KR (1) | KR19980063725A (no) |
| CN (1) | CN1184104A (no) |
| AR (1) | AR010328A1 (no) |
| AT (1) | ATE214371T1 (no) |
| AU (1) | AU743750B2 (no) |
| BR (1) | BR9706129A (no) |
| CA (1) | CA2223366A1 (no) |
| CZ (1) | CZ383297A3 (no) |
| DE (2) | DE19650215A1 (no) |
| HU (1) | HUP9702345A2 (no) |
| NO (1) | NO309717B1 (no) |
| NZ (1) | NZ329299A (no) |
| PL (1) | PL323517A1 (no) |
| SG (1) | SG65705A1 (no) |
| TR (1) | TR199701490A2 (no) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306839B1 (en) | 1998-09-16 | 2001-10-23 | Dow Agrosciences Llc | 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring |
| AU780698B2 (en) | 1999-07-20 | 2005-04-14 | Dow Agrosciences Llc | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation |
| FR2803592A1 (fr) * | 2000-01-06 | 2001-07-13 | Aventis Cropscience Sa | Nouveaux derives de l'acide 3-hydroxypicolinique, leur procede de preparation et compositions fongicides les contenant. |
| US8318703B2 (en) | 2001-12-06 | 2012-11-27 | Fibrogen, Inc. | Methods for improving kidney function |
| ES2686626T3 (es) * | 2001-12-06 | 2018-10-18 | Fibrogen, Inc. | Medicamentos para tratar anemia asociada con enfermedad renal |
| EP2295060B1 (en) | 2001-12-06 | 2018-10-31 | Fibrogen, Inc. | Treatment or prevention of ischemic or hypoxic conditions |
| US7618940B2 (en) * | 2002-12-06 | 2009-11-17 | Fibrogen, Inc. | Fat regulation |
| US8124582B2 (en) | 2002-12-06 | 2012-02-28 | Fibrogen, Inc. | Treatment of diabetes |
| US8614204B2 (en) * | 2003-06-06 | 2013-12-24 | Fibrogen, Inc. | Enhanced erythropoiesis and iron metabolism |
| JP5410751B2 (ja) | 2005-06-15 | 2014-02-05 | ファイブローゲン、インコーポレーテッド | がん治療のための化合物および方法 |
| WO2007101204A1 (en) * | 2006-02-27 | 2007-09-07 | Alcon Research, Ltd. | Method of treating glaucoma |
| US7745461B1 (en) | 2006-02-27 | 2010-06-29 | Alcon Research, Ltd. | Method of treating dry eye disorders |
| US7588924B2 (en) | 2006-03-07 | 2009-09-15 | Procter & Gamble Company | Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase |
| KR100934671B1 (ko) * | 2006-03-30 | 2009-12-31 | 엘지전자 주식회사 | 비디오 신호를 디코딩/인코딩하기 위한 방법 및 장치 |
| ES2354584T3 (es) * | 2006-06-26 | 2011-03-16 | Warner Chilcott Company, Llc | Inhibidores de prolilhidroxilasa y métodos de uso. |
| US8962530B2 (en) * | 2007-06-27 | 2015-02-24 | Regents Of The University Of Colorado | Inflammatory bowel disease therapies |
| RU2518416C2 (ru) | 2009-11-06 | 2014-06-10 | Аэрпио Терапьютикс Инк. | Композиции и способы лечения колита |
| EP3251671A1 (en) | 2011-06-06 | 2017-12-06 | Akebia Therapeutics Inc. | Compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer |
| NO2686520T3 (no) | 2011-06-06 | 2018-03-17 | ||
| NZ753904A (en) | 2013-06-13 | 2020-07-31 | Akebia Therapeutics Inc | Compositions and methods for treating anemia |
| TW201946625A (zh) | 2013-11-15 | 2019-12-16 | 美商阿克比治療有限公司 | {[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基}乙酸之固體型式，其組合物及用途 |
| AU2015209264A1 (en) * | 2014-01-23 | 2016-08-04 | Akebia Therapeutics, Inc. | Compositions and methods for treating ocular diseases |
| EP3247355A4 (en) | 2015-01-23 | 2018-06-13 | Akebia Therapeutics, Inc. | Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof |
| CN106146395B (zh) * | 2015-03-27 | 2019-01-01 | 沈阳三生制药有限责任公司 | 3-羟基吡啶化合物、其制备方法及其制药用途 |
| MA41863A (fr) | 2015-04-01 | 2021-06-02 | Akebia Therapeutics Inc | Compositions et procédés permettant de traiter une anémie |
| JP6814134B2 (ja) * | 2015-05-28 | 2021-01-13 | 日本たばこ産業株式会社 | 糖尿病性腎症を治療又は予防する方法 |
| CA3097219A1 (en) | 2018-05-09 | 2019-11-14 | Akebia Therapeutics, Inc. | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
| IT201900021960A1 (it) * | 2019-11-22 | 2021-05-22 | Isagro Spa | Composti ad attività fungicida, loro composizioni agronomiche e relativo metodo di preparazione |
| CN112979541B (zh) * | 2019-12-17 | 2022-11-11 | 浙江大学 | 一种基于n-(3-羟基吡啶-2-羰基)甘氨酸的抗肿瘤药物增敏剂及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4015255A1 (de) * | 1990-05-12 | 1991-11-14 | Hoechst Ag | Oxalyl-aminosaeurederivate, verfahren zu ihrer herstellung und ihrer verwendung als arzneimittel zur inhibierung der prolyl-hydroxylase |
| TW406076B (en) * | 1993-12-30 | 2000-09-21 | Hoechst Ag | Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals |
| IL135495A (en) * | 1995-09-28 | 2002-12-01 | Hoechst Ag | Intermediate compounds for the preparation of quinoline-converted amines - 2 - carboxylic acid |
-
1996
- 1996-12-04 DE DE19650215A patent/DE19650215A1/de not_active Withdrawn
-
1997
- 1997-11-24 DE DE59706602T patent/DE59706602D1/de not_active Expired - Lifetime
- 1997-11-24 EP EP97120537A patent/EP0846685B1/de not_active Expired - Lifetime
- 1997-11-24 AT AT97120537T patent/ATE214371T1/de not_active IP Right Cessation
- 1997-12-01 NO NO975513A patent/NO309717B1/no not_active IP Right Cessation
- 1997-12-02 AR ARP970105663A patent/AR010328A1/es unknown
- 1997-12-02 TR TR97/01490A patent/TR199701490A2/xx unknown
- 1997-12-02 CZ CZ973832A patent/CZ383297A3/cs unknown
- 1997-12-02 AU AU46792/97A patent/AU743750B2/en not_active Ceased
- 1997-12-02 NZ NZ329299A patent/NZ329299A/en unknown
- 1997-12-03 BR BR9706129A patent/BR9706129A/pt unknown
- 1997-12-03 CN CN97125404A patent/CN1184104A/zh active Pending
- 1997-12-03 KR KR1019970065494A patent/KR19980063725A/ko not_active Application Discontinuation
- 1997-12-03 HU HU9702345A patent/HUP9702345A2/hu unknown
- 1997-12-03 CA CA002223366A patent/CA2223366A1/en not_active Abandoned
- 1997-12-03 SG SG1997004280A patent/SG65705A1/en unknown
- 1997-12-04 PL PL97323517A patent/PL323517A1/xx unknown
- 1997-12-04 JP JP9334148A patent/JPH10168062A/ja active Pending
- 1997-12-04 US US08/985,266 patent/US6020350A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE59706602D1 (de) | 2002-04-18 |
| TR199701490A2 (xx) | 1998-06-22 |
| HUP9702345A2 (hu) | 2002-11-28 |
| JPH10168062A (ja) | 1998-06-23 |
| CN1184104A (zh) | 1998-06-10 |
| KR19980063725A (ko) | 1998-10-07 |
| EP0846685B1 (de) | 2002-03-13 |
| NO309717B1 (no) | 2001-03-19 |
| CZ383297A3 (cs) | 1998-06-17 |
| MX9709438A (es) | 1998-06-30 |
| AR010328A1 (es) | 2000-06-07 |
| AU743750B2 (en) | 2002-02-07 |
| CA2223366A1 (en) | 1998-06-04 |
| NO975513L (no) | 1998-06-05 |
| EP0846685A1 (de) | 1998-06-10 |
| PL323517A1 (en) | 1998-06-08 |
| DE19650215A1 (de) | 1998-06-10 |
| NO975513D0 (no) | 1997-12-01 |
| NZ329299A (en) | 1998-11-25 |
| AU4679297A (en) | 1998-06-11 |
| ATE214371T1 (de) | 2002-03-15 |
| BR9706129A (pt) | 1999-05-18 |
| HU9702345D0 (en) | 1998-03-02 |
| US6020350A (en) | 2000-02-01 |
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