DK0930875T3 - Fremgangsmåde til fremstilling af faste farmaceutiske former ved ekstrudering - Google Patents

Fremgangsmåde til fremstilling af faste farmaceutiske former ved ekstrudering

Info

Publication number
DK0930875T3
DK0930875T3 DK97942022T DK97942022T DK0930875T3 DK 0930875 T3 DK0930875 T3 DK 0930875T3 DK 97942022 T DK97942022 T DK 97942022T DK 97942022 T DK97942022 T DK 97942022T DK 0930875 T3 DK0930875 T3 DK 0930875T3
Authority
DK
Denmark
Prior art keywords
extrusion
preparation
solid pharmaceutical
pharmaceutical forms
shaping
Prior art date
Application number
DK97942022T
Other languages
Danish (da)
English (en)
Inventor
Joerg Breitenbach
Andreas Kleinke
Stephan Kothrade
Joerg Rosenberg
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19637479A external-priority patent/DE19637479A1/de
Priority claimed from DE19734011A external-priority patent/DE19734011A1/de
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK0930875T3 publication Critical patent/DK0930875T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK97942022T 1996-09-13 1997-09-11 Fremgangsmåde til fremstilling af faste farmaceutiske former ved ekstrudering DK0930875T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19637479A DE19637479A1 (de) 1996-09-13 1996-09-13 Verfahren zur Herstellung fester pharmazeutischer Formen
DE19734011A DE19734011A1 (de) 1997-08-06 1997-08-06 Verfahren zur Herstellung fester pharmazeutischer Formen
PCT/EP1997/004984 WO1998010752A2 (de) 1996-09-13 1997-09-11 Verfahren zur herstellung fester pharmazeutischer formen durch extrudierung

Publications (1)

Publication Number Publication Date
DK0930875T3 true DK0930875T3 (da) 2003-09-01

Family

ID=26029370

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97942022T DK0930875T3 (da) 1996-09-13 1997-09-11 Fremgangsmåde til fremstilling af faste farmaceutiske former ved ekstrudering

Country Status (19)

Country Link
US (1) US6221368B1 (ja)
EP (1) EP0930875B1 (ja)
JP (1) JP4975894B2 (ja)
KR (1) KR20000036066A (ja)
CN (1) CN1230109A (ja)
AT (1) ATE239452T1 (ja)
AU (1) AU720535B2 (ja)
BR (1) BR9711777A (ja)
CA (1) CA2265532C (ja)
CZ (1) CZ82999A3 (ja)
DE (1) DE59710059D1 (ja)
DK (1) DK0930875T3 (ja)
ES (1) ES2199373T3 (ja)
HR (1) HRP970485A2 (ja)
IL (1) IL128672A0 (ja)
SK (1) SK26099A3 (ja)
TR (1) TR199900563T2 (ja)
TW (1) TW474824B (ja)
WO (1) WO1998010752A2 (ja)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2241342C (en) * 1998-06-15 2000-02-08 Bernard Charles Sherman Pharmaceutical tablets comprising an nsaid and a prostaglandin
DE19857897A1 (de) * 1998-12-15 2000-06-21 Basf Ag Verfahren zur Herstellung wäßriger Polymerdispersionen
US6733789B1 (en) 1999-01-21 2004-05-11 Biovail Laboratories, Inc. Multiparticulate bisoprolol formulation
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
EP1175205B1 (en) * 1999-11-12 2006-06-14 Abbott Laboratories Solid dispersion comprising ritonavir, fenofibrate or griseofulvin
US20040185099A1 (en) * 2000-01-20 2004-09-23 Biovail Laboratories, Inc. Multiparticulate bisoprolol formulation
AU5702201A (en) * 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
GB0106469D0 (en) * 2001-03-15 2001-05-02 Syngenta Ltd Solid formulation
FR2823974B1 (fr) * 2001-04-25 2004-10-15 Pf Medicament Pastille medicamenteuse a liberation lente du principe actif
GB0113841D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
ATE444060T1 (de) 2001-06-22 2009-10-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren
US20030091633A1 (en) * 2001-11-15 2003-05-15 John Kelly Methods and compositions for use of (S)-bisoprolol
US20030118652A1 (en) * 2001-11-15 2003-06-26 John Kelly Methods and compositions for use of (S)-bisoprolol
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
US20060251724A1 (en) * 2003-05-06 2006-11-09 Farrell Thomas P Method for preparing thermoformed compositions containing acrylic polymer binders, pharmaceutical dosage forms and methods of preparing the same
JP2007528857A (ja) * 2003-07-11 2007-10-18 ミリアド ジェネティクス， インコーポレイテッド アルツハイマー病の処置のための薬学的方法、投与レジメンおよび投薬形態
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
WO2005053656A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions containing preferably a poloxamer and a glyceride
CA2547773A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate azithromycin compositions containing preferably a poloxamer and a glyceride
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
WO2005053651A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate compositions with improved stability
RU2006119453A (ru) * 2003-12-04 2007-12-20 Пфайзер Продактс Инк. (Us) Получение посредством основанных на применении жидкостей способов лекарственные формы азитромицина с большим количеством частиц
WO2005053655A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Method for making pharmaceutical multiparticulates
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
MXPA06012165A (es) * 2004-04-29 2007-01-17 Keystone Retaining Wall System Chapas para muros, muros de contencion y similares.
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
US7799744B2 (en) * 2005-03-09 2010-09-21 Halliburton Energy Services, Inc. Polymer coated particulates
US20090220596A1 (en) * 2005-07-05 2009-09-03 Abbott Gmbh & Co. Kg Composition and Dosage Form Comprising a Solid or Semi-Solid Matrix
KR20080039876A (ko) * 2005-07-22 2008-05-07 미리어드 제네틱스, 인크. 높은 약물 충진 제형 및 투여형
EP1832281A1 (en) * 2006-03-10 2007-09-12 Abbott GmbH & Co. KG Process for producing a solid dispersion of an active ingredient
US20080033045A1 (en) * 2006-07-07 2008-02-07 Myriad Genetics, Incorporated Treatment of psychiatric disorders
WO2008022745A1 (de) * 2006-08-23 2008-02-28 Bayer Cropscience Ag Formulierungen zur kontrollierten freisetzung agrochemischer wirkstoffe
US8399007B2 (en) * 2006-12-05 2013-03-19 Landec Corporation Method for formulating a controlled-release pharmaceutical formulation
AU2009240586A1 (en) * 2008-04-24 2009-10-29 Evestra, Inc. Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen
CN108421497A (zh) * 2018-04-03 2018-08-21 杨高品 药物连续化制粒的生产工艺和设备

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1388786A (en) 1972-04-03 1975-03-26 Scherer Corp R P Integral solid gel-lattice dosage form of high-moisture content
EP0080862B1 (en) * 1981-12-02 1985-09-25 Beecham Group Plc Pharmaceutical formulation comprising beta-lactam antibiotics
DE3208791A1 (de) 1982-03-11 1983-09-22 Röhm GmbH, 6100 Darmstadt Verfahren zum ueberziehen von arzneiformen mittes eines in wasser dispergierten ueberzugsmittels
DE3421860C2 (de) * 1984-06-13 1994-09-15 Roehm Gmbh Verfahren zum Überziehen von Arzneiformen
IL81419A0 (en) * 1986-01-30 1987-08-31 Syntex Inc Long acting sustained release pharmaceutical compositions containing dihydropyridines and their preparation
DE3612211A1 (de) 1986-04-11 1987-10-15 Basf Ag Kontinuierliches verfahren zum tablettieren
DE3612212A1 (de) 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
JPS63222112A (ja) 1987-03-10 1988-09-16 Nippon Soda Co Ltd 徐放性顆粒
JPS63222121A (ja) * 1987-03-10 1988-09-16 Nippon Soda Co Ltd 徐放性ゲル製剤
DE3812567A1 (de) 1988-04-15 1989-10-26 Basf Ag Verfahren zur herstellung pharmazeutischer mischungen
DE3830353A1 (de) 1988-09-07 1990-03-15 Basf Ag Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
DE4031881C2 (de) 1990-10-08 1994-02-24 Sanol Arznei Schwarz Gmbh Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung
GB9025372D0 (en) 1990-11-22 1991-01-09 Nat Res Dev Pharmaceutical dosage forms
NL9100691A (nl) * 1991-04-19 1992-11-16 Dmv Campina Bv Tabletteerhulpstof.
DE4138513A1 (de) 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
DE4141268A1 (de) 1991-12-14 1993-06-17 Merck Patent Gmbh Pharmazeutische zubereitung
US5260074A (en) * 1992-06-22 1993-11-09 Digestive Care Inc. Compositions of digestive enzymes and salts of bile acids and process for preparation thereof
JPH06218028A (ja) 1992-10-02 1994-08-09 Eisai Co Ltd 湿製錠の成型方法とその装置及び湿製錠
DE69432186T2 (de) * 1993-11-18 2004-05-06 Nippon Shinyaku Co., Ltd. Verfahren zur herstellung stabiler arzneimittel
WO1995019763A1 (en) * 1994-01-20 1995-07-27 New Zealand Pastorial Agriculture Research Institute Limited Device for administration of beneficial materials to ruminants
JP4194114B2 (ja) * 1994-02-23 2008-12-10 ビーエム リサーチ エイ／エス 制御放出組成物

Also Published As

Publication number Publication date
CA2265532C (en) 2006-04-04
EP0930875A2 (de) 1999-07-28
WO1998010752A3 (de) 1998-06-18
AU720535B2 (en) 2000-06-01
AU4384697A (en) 1998-04-02
BR9711777A (pt) 1999-08-24
JP4975894B2 (ja) 2012-07-11
CA2265532A1 (en) 1998-03-19
HRP970485A2 (en) 1998-08-31
SK26099A3 (en) 2000-03-13
ATE239452T1 (de) 2003-05-15
WO1998010752A2 (de) 1998-03-19
EP0930875B1 (de) 2003-05-07
US6221368B1 (en) 2001-04-24
IL128672A0 (en) 2000-01-31
JP2001500130A (ja) 2001-01-09
KR20000036066A (ko) 2000-06-26
DE59710059D1 (de) 2003-06-12
TW474824B (en) 2002-02-01
CN1230109A (zh) 1999-09-29
ES2199373T3 (es) 2004-02-16
CZ82999A3 (cs) 1999-06-16
TR199900563T2 (xx) 1999-07-21

Similar Documents

Publication Publication Date Title
DK0930875T3 (da) Fremgangsmåde til fremstilling af faste farmaceutiske former ved ekstrudering
DK1035841T3 (da) Fremgangsmåde til fremstilling af faste doseringsformer
KR930016091A (ko) 거의 수불용성인 약제의 고체 분산액을 제조하는 방법
DE59913682D1 (de) Verfahren zur Herstellung von festen Dosierungsformen
BR9404330A (pt) Dispositivo para misturar uma composição farmacêutica com um outro agente, processo para preparar um preparado farmacêutico mediante a mistura de uma composição farmacêutica com um agente, e, processo para a aplicação oral de um preparado farmacêutico.
FR2659959B1 (fr) Procede de projection de beton et melange utilise.
DK1284716T3 (da) Selvemulgerende aktivstofformulering og anvendelse af denne formulering
ES2037020T3 (es) Procedimiento para la obtencion de formas solidas farmaceuticas.
DE69216642D1 (de) Verfahren zur herstellung von tabletten mit hoher festigkeit
DE69112837T2 (de) Wasserlösliche pentacyclische triterpen-mischung sowie deren herstellung.
NZ510583A (en) Pharmaceutical composition comprising entacapone or nitecapone as well as a cross-linked cellulose derivative
PT1158962E (pt) Processo para a preparacao de formas de dosagem solidas que contem ciclodextrina
EP0187471A3 (en) Use of a substituted imidazole for the manufacture of a medicament useful as a sedative or analgesic
SE8201202L (sv) Anti-inflammatoriskt analgetiskt kataplasma
DE59909717D1 (de) Verfahren zur Herstellung von festen Dosierungsformen
IS1664B (is) Ný aðferð við að framleiða útskipt 4-fenýl-4-píperídínkarboxamíð sem hefur bæði staðbundin deyfandiog kvalastillandi áhrif
ES2163147T3 (es) Perfeccionamientos de agentes antimicrobianos de accion prolongada o relativos a los mismos.
HUT60245A (en) Insecticidal compositions comprising 2-aryl-1-(alkoxymethyl)-4-halogen-5-(trifluoromethyl)-pyrrole derivatives as active ingredient and process for producing the active ingredient
ES2083406T3 (es) Procedimiento para la obtencion de machos y moldes de fundicion.
TW350898B (en) Sliding member and manufacture thereof
BR9813037A (pt) Composto, processo para sua preparação, uso do mesmo, preparação farmacêutica, e, combinação desta com pelo menos uma outra substância ativa
KR860003176A (ko) 연탄재를 이용한 건자재의 제조방법
SV1998000012A (es) Metodo para la preparacion de (1s, 4r) -1-azabiciclo [2.2.1] heptano-3- uno y (1r,4s), 1-azabiciclo [2.2.1] heptano-3-uno.
ES2067622T3 (es) Proceso para preparar una composicion farmaceutica.
EP0146847A3 (en) Preparation for treating burns