DK0925273T3 - Farmaceutiske præparater indeholdende 4-oxo-butansyrer - Google Patents

Farmaceutiske præparater indeholdende 4-oxo-butansyrer

Info

Publication number
DK0925273T3
DK0925273T3 DK97936682T DK97936682T DK0925273T3 DK 0925273 T3 DK0925273 T3 DK 0925273T3 DK 97936682 T DK97936682 T DK 97936682T DK 97936682 T DK97936682 T DK 97936682T DK 0925273 T3 DK0925273 T3 DK 0925273T3
Authority
DK
Denmark
Prior art keywords
oxo
pharmaceutical preparations
preparations containing
butanoic acids
butanoic
Prior art date
Application number
DK97936682T
Other languages
Danish (da)
English (en)
Inventor
Gerard Moinet
Lilian Doare
Micheline Kergoat
Philippe Maizeray
Didier Mesangeau
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of DK0925273T3 publication Critical patent/DK0925273T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK97936682T 1996-08-16 1997-08-05 Farmaceutiske præparater indeholdende 4-oxo-butansyrer DK0925273T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9610254A FR2752422B1 (fr) 1996-08-16 1996-08-16 Composition pharmaceutique contenant des acides 4-oxo-butanoiques
PCT/EP1997/004252 WO1998007681A1 (fr) 1996-08-16 1997-08-05 Compositions pharmaceutiques contenant des acides 4-oxo-butanoiques

Publications (1)

Publication Number Publication Date
DK0925273T3 true DK0925273T3 (da) 2002-02-18

Family

ID=9495089

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97936682T DK0925273T3 (da) 1996-08-16 1997-08-05 Farmaceutiske præparater indeholdende 4-oxo-butansyrer

Country Status (30)

Country Link
US (1) US6143787A (id)
EP (1) EP0925273B1 (id)
JP (1) JP3105545B2 (id)
KR (1) KR100488430B1 (id)
CN (1) CN1082370C (id)
AR (1) AR009251A1 (id)
AT (1) ATE208364T1 (id)
AU (1) AU725440B2 (id)
BR (1) BR9711315A (id)
CA (1) CA2263348C (id)
CY (1) CY2298B1 (id)
CZ (1) CZ294165B6 (id)
DE (1) DE69708130T2 (id)
DK (1) DK0925273T3 (id)
ES (1) ES2166098T3 (id)
FR (1) FR2752422B1 (id)
HK (1) HK1021728A1 (id)
HU (1) HUP0004223A3 (id)
ID (1) ID17875A (id)
NO (1) NO312290B1 (id)
PL (1) PL187371B1 (id)
PT (1) PT925273E (id)
RU (1) RU2175966C2 (id)
SI (1) SI0925273T1 (id)
SK (1) SK283055B6 (id)
TR (1) TR199900329T2 (id)
TW (1) TW438764B (id)
UA (1) UA57031C2 (id)
WO (1) WO1998007681A1 (id)
ZA (1) ZA977327B (id)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04318852A (ja) * 1991-04-18 1992-11-10 Fujitsu Ltd レジスト・パターン形成方法
CN100344616C (zh) 2001-06-12 2007-10-24 维尔斯达医疗公司 用于治疗代谢失调的化合物
FR2832633B1 (fr) * 2001-11-28 2004-09-24 Lipha Composition pharmaceutique comprenant une association metformine et un acide 4-oxo-butanoique et son utilisation pour traiter le diabete
FR2832925B1 (fr) * 2001-12-03 2006-07-14 Lipha Utilisation de derives de l'acide 4-oxobutanoique dans le traitement de l'inflammation
FR2834214B1 (fr) * 2001-12-28 2004-09-24 Lipha Composition pharmaceutique comprenant un inhibiteur d'alpha-glucosidase et un acide 4-oxo-butanoique et son utilisation pour traiter le diabete
FR2834640B1 (fr) * 2002-01-11 2004-09-24 Lipha Composition pharmaceutique comprenant une glitazone et un acide 4-oxobutanoique et son utilisation pour traiter le diabete
EP1556085A4 (en) * 2002-11-01 2012-08-22 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
EP1575575B1 (en) * 2002-11-08 2010-05-19 High Point Pharmaceuticals, LLC Safe chemical uncouplers for the treatment of obesity
FR2849599B1 (fr) * 2003-01-07 2006-12-29 Merck Sante Sas Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete
FR2849598B1 (fr) * 2003-01-07 2006-09-22 Merck Sante Sas Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete, par augmentation du nombre de cellules des ilots de langerhans
CN101912380A (zh) * 2003-04-15 2010-12-15 维尔斯达医疗公司 用于治疗代谢紊乱的化合物
WO2009071161A1 (en) 2007-12-03 2009-06-11 Merck Patent Gmbh Use of 4-oxobutanoic acid derivatives in the treatment of pathologies associated with immunological disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK523288A (da) * 1987-10-06 1989-04-07 Hoffmann La Roche Aminosyrederivater
US5250517A (en) * 1987-10-06 1993-10-05 Hoffmann-La Roche Inc. Renin inhibiting compounds
CA1329680C (en) * 1987-11-23 1994-05-17 Harold Norris Weller, Iii N-heterocyclic alcohol derivatives
US5055466A (en) * 1987-11-23 1991-10-08 E. R. Squibb & Sons, Inc. N-morpholino derivatives and their use as anti-hypertensive agents

Also Published As

Publication number Publication date
KR20000068106A (ko) 2000-11-25
HK1021728A1 (en) 2000-06-30
FR2752422A1 (fr) 1998-02-20
ATE208364T1 (de) 2001-11-15
PT925273E (pt) 2002-04-29
CN1227538A (zh) 1999-09-01
EP0925273A1 (fr) 1999-06-30
BR9711315A (pt) 1999-08-17
US6143787A (en) 2000-11-07
RU2175966C2 (ru) 2001-11-20
ES2166098T3 (es) 2002-04-01
ID17875A (id) 1998-02-05
HUP0004223A2 (hu) 2001-04-28
CN1082370C (zh) 2002-04-10
SI0925273T1 (en) 2002-04-30
DE69708130T2 (de) 2002-06-20
KR100488430B1 (ko) 2005-05-10
CZ49899A3 (cs) 1999-05-12
SK283055B6 (sk) 2003-02-04
EP0925273B1 (fr) 2001-11-07
SK18099A3 (en) 2000-03-13
ZA977327B (en) 1998-03-30
FR2752422B1 (fr) 1998-11-06
CA2263348C (en) 2008-05-13
NO312290B1 (no) 2002-04-22
JP2000506543A (ja) 2000-05-30
NO990707D0 (no) 1999-02-15
UA57031C2 (uk) 2003-06-16
PL331645A1 (en) 1999-08-02
PL187371B1 (pl) 2004-06-30
WO1998007681A1 (fr) 1998-02-26
CZ294165B6 (cs) 2004-10-13
TW438764B (en) 2001-06-07
AU3942297A (en) 1998-03-06
TR199900329T2 (xx) 1999-04-21
DE69708130D1 (de) 2001-12-13
AU725440B2 (en) 2000-10-12
AR009251A1 (es) 2000-04-12
JP3105545B2 (ja) 2000-11-06
HUP0004223A3 (en) 2001-12-28
NO990707L (no) 1999-02-15
CY2298B1 (en) 2003-07-04
CA2263348A1 (fr) 1998-02-26

Similar Documents

Publication Publication Date Title
NO974618D0 (no) Farmasöytiske preparater for intranasal administrasjon
DE69814091D1 (de) Voriconazol-enthaltende pharmazeutische zubereitungen
DE69831620D1 (de) Arzneizubereitungen enthaltend Kannabinoide
DK0981375T3 (da) Farmaceutiske præparater indeholdende plasmaprotein
BR9611367A (pt) Formulação farmacêutic liofilizada estável
BR9610153A (pt) Formulações farmacêuticas
BR9611626A (pt) Formulações farmacéuticas
NO986023D0 (no) Vannbaserte farmas÷ytiske preparater
NO954146D0 (no) Belagte farmasöytiske preparater
DE69625368T2 (de) Schweisshemmende deodorierende präparaten
ID24654A (id) Formulasi farmasi omeprazola
NO965539D0 (no) Farmasöytiske tacrinepreparater
DK0921796T3 (da) Tetrahydrolipstatinholdige præparater
NO954486D0 (no) Farmasöytiske formuleringsgrunnlag
DE69823830D1 (de) Dermatologische zubereitungen
BR9610396A (pt) Formulação farmacêutica
DE59707298D1 (de) Desodorierende zubereitungen
DK0925273T3 (da) Farmaceutiske præparater indeholdende 4-oxo-butansyrer
ID16781A (id) Formulasi-formulasi farmasi
ITMI941169A0 (it) Formulazioni farmaceutiche
DE69926012D1 (de) Arzneizubereitungen
DK1041966T3 (da) Farmaceutiske præparater omfattende zafirlukast
EE9800275A (et) Misolastiini sisaldavad prolongeeritud toimega farmatseutilised preparaadid
FI973230A (fi) Uusi farmaseuttinen formulaatio
FI951155A0 (fi) Farmaseuttinen valmiste