DK0917458T3 - Lyofiliserede thioxanthenon-antitumormidler - Google Patents

Lyofiliserede thioxanthenon-antitumormidler

Info

Publication number
DK0917458T3
DK0917458T3 DK96929491T DK96929491T DK0917458T3 DK 0917458 T3 DK0917458 T3 DK 0917458T3 DK 96929491 T DK96929491 T DK 96929491T DK 96929491 T DK96929491 T DK 96929491T DK 0917458 T3 DK0917458 T3 DK 0917458T3
Authority
DK
Denmark
Prior art keywords
lyophilized
antitumor agents
thioxanthenone
thioxanthenone antitumor
mannitol
Prior art date
Application number
DK96929491T
Other languages
Danish (da)
English (en)
Inventor
Stephen Brown
Gurdial Singh Sandhu
Original Assignee
Sanofi Synthelabo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo Inc filed Critical Sanofi Synthelabo Inc
Application granted granted Critical
Publication of DK0917458T3 publication Critical patent/DK0917458T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/67Phosphorus compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DK96929491T 1995-09-18 1996-09-12 Lyofiliserede thioxanthenon-antitumormidler DK0917458T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/529,934 US5665760A (en) 1995-09-18 1995-09-18 Lyophilized thioxanthenone antitumor agents
PCT/IB1996/000984 WO1997010809A1 (en) 1995-09-18 1996-09-12 Lyophilized thioxanthenone antimumor agents

Publications (1)

Publication Number Publication Date
DK0917458T3 true DK0917458T3 (da) 2003-07-28

Family

ID=24111801

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96929491T DK0917458T3 (da) 1995-09-18 1996-09-12 Lyofiliserede thioxanthenon-antitumormidler

Country Status (20)

Country Link
US (1) US5665760A (es)
EP (1) EP0917458B1 (es)
JP (1) JP2001503374A (es)
KR (1) KR100475385B1 (es)
CN (1) CN1178651C (es)
AT (1) ATE235888T1 (es)
AU (1) AU716782B2 (es)
CA (1) CA2232444A1 (es)
CZ (1) CZ293433B6 (es)
DE (1) DE69627209T2 (es)
DK (1) DK0917458T3 (es)
ES (1) ES2196171T3 (es)
HK (1) HK1016891A1 (es)
HU (1) HUP9900246A3 (es)
NO (1) NO320367B1 (es)
NZ (1) NZ316609A (es)
PL (1) PL185164B1 (es)
PT (1) PT917458E (es)
RU (1) RU2157189C2 (es)
WO (1) WO1997010809A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952300A (en) * 1996-04-19 1999-09-14 Merck & Co., Inc. Antifungal compositions
US6407278B2 (en) * 1998-11-16 2002-06-18 Medimmune Oncology, Inc. Stable amorphous amifostine compositions and methods for the preparation and use of the same
GB0115893D0 (en) * 2001-06-28 2001-08-22 Sanofi Synthelabo Formulations
US7378408B2 (en) * 2001-11-30 2008-05-27 Pfizer Inc. Methods of treatment and formulations of cephalosporin
JP2007526329A (ja) * 2004-03-04 2007-09-13 ワイス 賦形剤の結晶化を改善するための凍結乾燥法
WO2007075452A2 (en) * 2005-12-16 2007-07-05 Wyeth Lyophilized compositions of a triazolopyrimidine compound
TW201021855A (en) * 2008-11-13 2010-06-16 Taigen Biotechnology Co Ltd Lyophilization formulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582851A (en) * 1984-02-06 1986-04-15 Warner-Lambert Company Anti-bacterial 1,4-aminoalkylamino-9H-thioxanthen-9-one derivatives, compositions, and method of use therefor
US5091410A (en) * 1991-06-10 1992-02-25 Sterling Winthrop Inc. Thioxanthenone antitumor agents
AU642596B2 (en) * 1991-06-10 1993-10-21 Sanofi-Synthelabo Thioxanthenone antitumor agents
US5346917A (en) * 1991-06-10 1994-09-13 Sterling Winthrop Inc. Thioxanthenone antitumor agents

Also Published As

Publication number Publication date
RU2157189C2 (ru) 2000-10-10
DE69627209D1 (en) 2003-05-08
AU716782B2 (en) 2000-03-09
PT917458E (pt) 2003-08-29
EP0917458B1 (en) 2003-04-02
NO981205L (no) 1998-05-15
HUP9900246A3 (en) 2002-12-28
US5665760A (en) 1997-09-09
ATE235888T1 (de) 2003-04-15
CN1201387A (zh) 1998-12-09
HUP9900246A2 (hu) 2001-04-28
NZ316609A (en) 1999-05-28
MX9802143A (es) 1998-05-31
CA2232444A1 (en) 1997-03-27
PL325603A1 (en) 1998-08-03
CN1178651C (zh) 2004-12-08
NO981205D0 (no) 1998-03-17
PL185164B1 (pl) 2003-03-31
HK1016891A1 (en) 1999-11-12
WO1997010809A1 (en) 1997-03-27
CZ79998A3 (cs) 1998-08-12
ES2196171T3 (es) 2003-12-16
EP0917458A1 (en) 1999-05-26
KR19990045741A (ko) 1999-06-25
AU6888096A (en) 1997-04-09
KR100475385B1 (ko) 2006-03-23
CZ293433B6 (cs) 2004-04-14
NO320367B1 (no) 2005-11-28
JP2001503374A (ja) 2001-03-13
DE69627209T2 (de) 2004-02-19

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