HK1016891A1 - Lyophilized thioxanthenone antitumor agents. - Google Patents

Lyophilized thioxanthenone antitumor agents.

Info

Publication number
HK1016891A1
HK1016891A1 HK99102048A HK99102048A HK1016891A1 HK 1016891 A1 HK1016891 A1 HK 1016891A1 HK 99102048 A HK99102048 A HK 99102048A HK 99102048 A HK99102048 A HK 99102048A HK 1016891 A1 HK1016891 A1 HK 1016891A1
Authority
HK
Hong Kong
Prior art keywords
lyophilized
antitumor agents
thioxanthenone
thioxanthenone antitumor
mannitol
Prior art date
Application number
HK99102048A
Other languages
English (en)
Inventor
Stephen Brown
Gurdial Singh Sandu
Original Assignee
Sanofi Synthelabo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo Inc filed Critical Sanofi Synthelabo Inc
Publication of HK1016891A1 publication Critical patent/HK1016891A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
HK99102048A 1995-09-18 1999-05-06 Lyophilized thioxanthenone antitumor agents. HK1016891A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/529,934 US5665760A (en) 1995-09-18 1995-09-18 Lyophilized thioxanthenone antitumor agents
PCT/IB1996/000984 WO1997010809A1 (en) 1995-09-18 1996-09-12 Lyophilized thioxanthenone antimumor agents

Publications (1)

Publication Number Publication Date
HK1016891A1 true HK1016891A1 (en) 1999-11-12

Family

ID=24111801

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99102048A HK1016891A1 (en) 1995-09-18 1999-05-06 Lyophilized thioxanthenone antitumor agents.

Country Status (20)

Country Link
US (1) US5665760A (es)
EP (1) EP0917458B1 (es)
JP (1) JP2001503374A (es)
KR (1) KR100475385B1 (es)
CN (1) CN1178651C (es)
AT (1) ATE235888T1 (es)
AU (1) AU716782B2 (es)
CA (1) CA2232444A1 (es)
CZ (1) CZ293433B6 (es)
DE (1) DE69627209T2 (es)
DK (1) DK0917458T3 (es)
ES (1) ES2196171T3 (es)
HK (1) HK1016891A1 (es)
HU (1) HUP9900246A3 (es)
NO (1) NO320367B1 (es)
NZ (1) NZ316609A (es)
PL (1) PL185164B1 (es)
PT (1) PT917458E (es)
RU (1) RU2157189C2 (es)
WO (1) WO1997010809A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952300A (en) * 1996-04-19 1999-09-14 Merck & Co., Inc. Antifungal compositions
US6407278B2 (en) * 1998-11-16 2002-06-18 Medimmune Oncology, Inc. Stable amorphous amifostine compositions and methods for the preparation and use of the same
GB0115893D0 (en) * 2001-06-28 2001-08-22 Sanofi Synthelabo Formulations
US7378408B2 (en) * 2001-11-30 2008-05-27 Pfizer Inc. Methods of treatment and formulations of cephalosporin
JP2007526329A (ja) * 2004-03-04 2007-09-13 ワイス 賦形剤の結晶化を改善するための凍結乾燥法
WO2007075452A2 (en) * 2005-12-16 2007-07-05 Wyeth Lyophilized compositions of a triazolopyrimidine compound
TW201021855A (en) * 2008-11-13 2010-06-16 Taigen Biotechnology Co Ltd Lyophilization formulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582851A (en) * 1984-02-06 1986-04-15 Warner-Lambert Company Anti-bacterial 1,4-aminoalkylamino-9H-thioxanthen-9-one derivatives, compositions, and method of use therefor
US5091410A (en) * 1991-06-10 1992-02-25 Sterling Winthrop Inc. Thioxanthenone antitumor agents
AU642596B2 (en) * 1991-06-10 1993-10-21 Sanofi-Synthelabo Thioxanthenone antitumor agents
US5346917A (en) * 1991-06-10 1994-09-13 Sterling Winthrop Inc. Thioxanthenone antitumor agents

Also Published As

Publication number Publication date
RU2157189C2 (ru) 2000-10-10
DE69627209D1 (en) 2003-05-08
AU716782B2 (en) 2000-03-09
PT917458E (pt) 2003-08-29
EP0917458B1 (en) 2003-04-02
NO981205L (no) 1998-05-15
HUP9900246A3 (en) 2002-12-28
US5665760A (en) 1997-09-09
ATE235888T1 (de) 2003-04-15
CN1201387A (zh) 1998-12-09
HUP9900246A2 (hu) 2001-04-28
NZ316609A (en) 1999-05-28
MX9802143A (es) 1998-05-31
CA2232444A1 (en) 1997-03-27
DK0917458T3 (da) 2003-07-28
PL325603A1 (en) 1998-08-03
CN1178651C (zh) 2004-12-08
NO981205D0 (no) 1998-03-17
PL185164B1 (pl) 2003-03-31
WO1997010809A1 (en) 1997-03-27
CZ79998A3 (cs) 1998-08-12
ES2196171T3 (es) 2003-12-16
EP0917458A1 (en) 1999-05-26
KR19990045741A (ko) 1999-06-25
AU6888096A (en) 1997-04-09
KR100475385B1 (ko) 2006-03-23
CZ293433B6 (cs) 2004-04-14
NO320367B1 (no) 2005-11-28
JP2001503374A (ja) 2001-03-13
DE69627209T2 (de) 2004-02-19

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080911