DK0888452T3 - Human CYR61, et ekstracellulært matrix-signalmolekyle - Google Patents
Human CYR61, et ekstracellulært matrix-signalmolekyleInfo
- Publication number
- DK0888452T3 DK0888452T3 DK97916018T DK97916018T DK0888452T3 DK 0888452 T3 DK0888452 T3 DK 0888452T3 DK 97916018 T DK97916018 T DK 97916018T DK 97916018 T DK97916018 T DK 97916018T DK 0888452 T3 DK0888452 T3 DK 0888452T3
- Authority
- DK
- Denmark
- Prior art keywords
- ecm signalling
- signalling molecules
- mammalian ecm
- methods
- mammalian
- Prior art date
Links
- 230000011664 signaling Effects 0.000 title abstract 8
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 title 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 title 1
- 101000777577 Homo sapiens CCN family member 1 Proteins 0.000 title 1
- 210000002744 extracellular matrix Anatomy 0.000 title 1
- 102000049732 human CCN1 Human genes 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 208000005623 Carcinogenesis Diseases 0.000 abstract 2
- 230000033115 angiogenesis Effects 0.000 abstract 2
- 230000036952 cancer formation Effects 0.000 abstract 2
- 231100000504 carcinogenesis Toxicity 0.000 abstract 2
- 230000022159 cartilage development Effects 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 1
- 102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 1
- 101150042405 CCN1 gene Proteins 0.000 abstract 1
- 108091026890 Coding region Proteins 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 102000007079 Peptide Fragments Human genes 0.000 abstract 1
- 108010033276 Peptide Fragments Proteins 0.000 abstract 1
- 230000031018 biological processes and functions Effects 0.000 abstract 1
- 239000010836 blood and blood product Substances 0.000 abstract 1
- 229940125691 blood product Drugs 0.000 abstract 1
- 230000021164 cell adhesion Effects 0.000 abstract 1
- 230000012292 cell migration Effects 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1395896P | 1996-03-15 | 1996-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0888452T3 true DK0888452T3 (da) | 2004-06-14 |
Family
ID=21762734
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97916018T DK0888452T3 (da) | 1996-03-15 | 1997-03-14 | Human CYR61, et ekstracellulært matrix-signalmolekyle |
Country Status (11)
Country | Link |
---|---|
US (3) | US6413735B1 (de) |
EP (1) | EP0888452B1 (de) |
JP (1) | JP4307552B2 (de) |
CN (1) | CN1263852C (de) |
AT (1) | ATE259419T1 (de) |
AU (1) | AU733382B2 (de) |
CA (1) | CA2248549A1 (de) |
DE (1) | DE69727558T2 (de) |
DK (1) | DK0888452T3 (de) |
HK (1) | HK1018707A1 (de) |
WO (1) | WO1997033995A2 (de) |
Families Citing this family (67)
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---|---|---|---|---|
PT804562E (pt) | 1994-07-12 | 2003-02-28 | Human Genome Sciences Inc | Factor 2 de crescimento de tecido conjuntivo |
US7026299B2 (en) | 1994-07-12 | 2006-04-11 | Human Genome Sciences, Inc. | Connective tissue growth factor-2 |
US7521540B2 (en) | 1996-03-15 | 2009-04-21 | Munin Corporation | CYR61 compositions and methods |
WO1997033995A2 (en) | 1996-03-15 | 1997-09-18 | Munin Corporation | Extracellular matrix signalling molecules |
WO1999033878A1 (fr) | 1997-12-25 | 1999-07-08 | Japan Tobacco Inc. | Anticorps monoclonal contre le facteur de croissance du tissu conjonctif et ses mises en applications medicales |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
CN1796556A (zh) * | 1998-03-20 | 2006-07-05 | 联邦科学和工业研究组织 | 控制基因表达 |
ATE418730T1 (de) | 1998-08-20 | 2009-01-15 | Chugai Pharmaceutical Co Ltd | Verfahren zum screenen von potenziellen verbindungen für das auffinden von einem anti- tumor-arzneistoff |
RU2268744C2 (ru) | 1999-07-14 | 2006-01-27 | Ново Нордиск А/С | ПРИМЕНЕНИЕ FVIIa ИЛИ АНТАГОНИСТА ТКАНЕВОГО ФАКТОРА ДЛЯ РЕГУЛЯЦИИ ГЕННОЙ ЭКСПРЕССИИ И КЛЕТОЧНОЙ МИГРАЦИИ ИЛИ ХЕМОТАКСИСА |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
DK1254169T3 (da) * | 1999-12-30 | 2007-08-06 | Harvard College | Fremgangsmåde vedrörende modulering af aktivitet af Th2-celledelmængde ved modulering af aktivitet af XBP-1 |
AU2001234721B8 (en) * | 2000-01-31 | 2006-07-27 | Munin Corporation | Human Cyr61 |
EP1892250A3 (de) * | 2000-01-31 | 2008-09-17 | Munin Corporation | CYR61-Zusammensetzungen und Verfahren |
US7037332B2 (en) * | 2000-03-15 | 2006-05-02 | Orbus Medical Technologies, Inc. | Medical device with coating that promotes endothelial cell adherence |
US8460367B2 (en) | 2000-03-15 | 2013-06-11 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
AU2001271365A1 (en) * | 2000-06-21 | 2002-01-02 | Wyeth | Cyr61 as a target for treatment and diagnosis of breast cancer |
AU2001276868A1 (en) * | 2000-07-11 | 2002-01-21 | Human Genome Sciences, Inc. | Connective tissue growth factor-2 |
PT1642885E (pt) | 2000-08-29 | 2009-12-17 | Biocon Ltd | Utilização de uma composição farmacêutica contendo um derviado de ácido para-aminofenilacético para o tratamento de estados inflamatórios do tracto gastrointestinal |
JP2005508133A (ja) | 2001-01-11 | 2005-03-31 | キュラジェン コーポレイション | タンパク質およびそれをコードする核酸 |
US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
CA2508880C (en) | 2002-12-16 | 2018-02-06 | Technion Research And Development Foundation Ltd. | Methods of preparing feeder cells-free, xeno-free human embryonic stem cells and stem cell cultures prepared using same |
WO2004090109A2 (en) * | 2003-03-31 | 2004-10-21 | Munin Corporation | Ccn3 compositions and methods |
JP2004315480A (ja) * | 2003-04-21 | 2004-11-11 | Yoshiyuki Kakehi | 前立腺疾患治療用医薬組成物 |
WO2005040191A2 (en) * | 2003-06-20 | 2005-05-06 | Munin Corporation | Ccn1 compositions and methods |
US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
PL1649013T3 (pl) | 2003-06-27 | 2016-07-29 | Depuy Synthes Products Inc | Regeneracja i naprawa chrząstki i kości z wykorzystaniem komórek poporodowych |
US8491883B2 (en) | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
US20050177885A1 (en) * | 2004-02-09 | 2005-08-11 | Lau Lester F. | CCN1 transgenic animals |
EP1773767B1 (de) | 2004-07-07 | 2016-03-09 | Biocon Limited | Synthese von azogebundenen, das immunsystem regulierenden verbindungen |
CA2589041C (en) * | 2004-12-23 | 2019-08-20 | Ethicon, Incorporated | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
JP5425399B2 (ja) | 2004-12-23 | 2014-02-26 | エシコン・インコーポレイテッド | 産褥由来細胞を用いたパーキンソン病および関連の障害の治療 |
US20070037186A1 (en) | 2005-05-20 | 2007-02-15 | Yuqiu Jiang | Thyroid fine needle aspiration molecular assay |
WO2007026353A2 (en) | 2005-08-29 | 2007-03-08 | Technion Research & Development Foundation Ltd. | Media for culturing stem cells |
CN101374946B (zh) | 2005-12-16 | 2017-07-18 | 伊西康公司 | 用于在组织相容性不匹配的移植中抑制有害的免疫反应的组合物和方法 |
US8741638B2 (en) | 2005-12-19 | 2014-06-03 | DePuy Synthes Products, LLC | In vitro expansion of postpartum-derived cells in roller bottles |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
US9040297B2 (en) | 2006-08-02 | 2015-05-26 | Technion Research & Development Foundation Limited | Methods of expanding embryonic stem cells in a suspension culture |
AU2008308531B2 (en) | 2007-10-05 | 2014-04-24 | Ethicon, Incorporated | Repair and regeneration of renal tissue using human umbilical cord tissue-derived cells |
US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
ES2621610T3 (es) * | 2007-12-27 | 2017-07-04 | DePuy Synthes Products, Inc. | Tratamiento de la degeneración de discos intervertebrales utilizando células derivadas de tejido cordón umbilical humano |
US8227184B2 (en) * | 2008-01-14 | 2012-07-24 | President And Fellows Of Harvard College | Methods for modulating de novo hepatic lipogenesis by modulating XBP-1 activity |
CN101747435B (zh) * | 2008-12-18 | 2013-06-19 | 上海市免疫学研究所 | 一种中和cyr61的单克隆抗体(杂交瘤)及其应用 |
ES2665883T3 (es) | 2008-12-19 | 2018-04-30 | DePuy Synthes Products, Inc. | Tratamiento de enfermedades y trastornos pulmonares y pulmonares |
US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
EP2411504B1 (de) | 2009-03-26 | 2017-05-10 | DePuy Synthes Products, Inc. | Humane nabelschnur gewebezellen in der alzheimer therapie |
TW201102086A (en) * | 2009-06-04 | 2011-01-16 | Hoffmann La Roche | Antibodies against human CCN1 and uses thereof |
US9018010B2 (en) | 2009-11-12 | 2015-04-28 | Technion Research & Development Foundation Limited | Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state |
EP2540742A4 (de) * | 2009-12-04 | 2014-02-12 | Shanghai Inst Of Immunology | Monoklonale antikörper gegen das protein cyr61 und anwendungen davon |
WO2011107590A1 (en) | 2010-03-04 | 2011-09-09 | Wolfgang Poller | Cnn1 (cyr61) for prevention and therapy of inflammatory disease |
DE102010010288A1 (de) | 2010-03-04 | 2011-09-08 | Wolfgang Poller | CCN1 zur Prävention und Therapie von entzündlichen Erkrankungen |
SG191028A1 (en) | 2010-12-06 | 2013-07-31 | Thd Spa | Method for the diagnosis of a carcinoma and uses thereof |
WO2012109238A2 (en) | 2011-02-07 | 2012-08-16 | President And Fellows Of Harvard College | Methods for increasing immune responses using agents that directly bind to and activate ire-1 |
AU2012358810B2 (en) | 2011-12-23 | 2018-03-15 | DePuy Synthes Products, Inc. | Detection of human umbilical cord tissue-derived cells |
US20150018406A1 (en) | 2012-03-09 | 2015-01-15 | Cornell University | Modulation of breast cancer growth by modulation of xbp1 activity |
US10092607B2 (en) | 2013-04-12 | 2018-10-09 | MangoGen Pharma, Inc. | Therapeutic viral microparticles for promoting stent biofunctionality and wound healing in vertebrate individuals |
WO2015013875A1 (zh) * | 2013-07-30 | 2015-02-05 | 杭州微基质生物科技有限公司 | 一种全能干细胞培养方法 |
WO2015048331A1 (en) | 2013-09-25 | 2015-04-02 | Cornell University | Compounds for inducing anti-tumor immunity and methods thereof |
CN105396136B (zh) * | 2015-11-23 | 2018-10-30 | 上海交通大学医学院附属第九人民医院 | CCN1(Cyr61)在治疗皮肤损伤及皮肤萎缩相关疾病中的应用 |
US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
CN110938128B (zh) * | 2019-11-08 | 2021-07-13 | 上海交通大学 | 一种生物活性多肽pkcpkcdkevyfaervtsl及其制备方法和应用 |
CH716377B1 (it) * | 2020-08-05 | 2020-12-30 | Contrad Swiss Sa | Idrogel ad applicazione topica efficace nel prevenire e/o attenuare la degenerazione della cartilagine. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
JPH05255397A (ja) * | 1991-01-18 | 1993-10-05 | Bristol Myers Squibb Co | TGF−β誘導遺伝子系統群 |
US5770209A (en) | 1991-08-30 | 1998-06-23 | University Of South Florida | Acceleration of wound healing using connective tissue growth factor |
US5408040A (en) * | 1991-08-30 | 1995-04-18 | University Of South Florida | Connective tissue growth factor(CTGF) |
ES2136092T3 (es) * | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
US5817310A (en) * | 1991-12-02 | 1998-10-06 | Cor Therapeutics, Inc. | Inhibitory immunoglobulin polypeptides to human PDGF beta receptor |
PT804562E (pt) | 1994-07-12 | 2003-02-28 | Human Genome Sciences Inc | Factor 2 de crescimento de tecido conjuntivo |
WO1997033995A2 (en) | 1996-03-15 | 1997-09-18 | Munin Corporation | Extracellular matrix signalling molecules |
EP0907719A4 (de) | 1996-03-20 | 2003-02-19 | Human Genome Sciences Inc | Menschliches zytokinpolypeptid |
-
1997
- 1997-03-14 WO PCT/US1997/004193 patent/WO1997033995A2/en active IP Right Grant
- 1997-03-14 CN CNB971946094A patent/CN1263852C/zh not_active Expired - Fee Related
- 1997-03-14 AT AT97916018T patent/ATE259419T1/de not_active IP Right Cessation
- 1997-03-14 EP EP97916018A patent/EP0888452B1/de not_active Expired - Lifetime
- 1997-03-14 US US09/142,569 patent/US6413735B1/en not_active Expired - Fee Related
- 1997-03-14 JP JP53289897A patent/JP4307552B2/ja not_active Expired - Lifetime
- 1997-03-14 DE DE69727558T patent/DE69727558T2/de not_active Expired - Lifetime
- 1997-03-14 CA CA002248549A patent/CA2248549A1/en not_active Abandoned
- 1997-03-14 AU AU23296/97A patent/AU733382B2/en not_active Expired
- 1997-03-14 DK DK97916018T patent/DK0888452T3/da active
-
1999
- 1999-08-30 HK HK99103723A patent/HK1018707A1/xx not_active IP Right Cessation
-
2002
- 2002-01-22 US US10/053,753 patent/US7064185B2/en not_active Expired - Fee Related
-
2006
- 2006-06-19 US US11/455,506 patent/US20060257965A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69727558D1 (de) | 2004-03-18 |
ATE259419T1 (de) | 2004-02-15 |
US6413735B1 (en) | 2002-07-02 |
US7064185B2 (en) | 2006-06-20 |
HK1018707A1 (en) | 2000-01-04 |
CN1222193A (zh) | 1999-07-07 |
EP0888452A2 (de) | 1999-01-07 |
JP2000506732A (ja) | 2000-06-06 |
EP0888452B1 (de) | 2004-02-11 |
DE69727558T2 (de) | 2004-12-16 |
CA2248549A1 (en) | 1997-09-18 |
CN1263852C (zh) | 2006-07-12 |
WO1997033995A2 (en) | 1997-09-18 |
US20020150986A1 (en) | 2002-10-17 |
JP4307552B2 (ja) | 2009-08-05 |
AU733382B2 (en) | 2001-05-10 |
AU2329697A (en) | 1997-10-01 |
US20060257965A1 (en) | 2006-11-16 |
WO1997033995A3 (en) | 1998-01-08 |
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