WO2001000664A3 - Secreted alpha-helical protein-36 - Google Patents

Secreted alpha-helical protein-36 Download PDF

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Publication number
WO2001000664A3
WO2001000664A3 PCT/US2000/017698 US0017698W WO0100664A3 WO 2001000664 A3 WO2001000664 A3 WO 2001000664A3 US 0017698 W US0017698 W US 0017698W WO 0100664 A3 WO0100664 A3 WO 0100664A3
Authority
WO
WIPO (PCT)
Prior art keywords
zalpha36
helical protein
secreted alpha
protein
polypeptides
Prior art date
Application number
PCT/US2000/017698
Other languages
French (fr)
Other versions
WO2001000664A2 (en
Inventor
Darrell C Conklin
Zeren Gao
Jane K Heffernan
Patricia A Mckernan
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to CA002415095A priority Critical patent/CA2415095A1/en
Priority to AU58953/00A priority patent/AU5895300A/en
Publication of WO2001000664A2 publication Critical patent/WO2001000664A2/en
Publication of WO2001000664A3 publication Critical patent/WO2001000664A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to polynucleotide and polypeptide molecules for mammalian secreted alpha helical protein-36 (Zalpha36). The polypeptides, and polynucleotides encoding them, are hormonal and may be used to regulate the functioning of the immune system. The present invention also includes antibodies to the Zalpha36 polypeptides. The Zalpha36 protein can be used to stimulate the production of leukocytes and to inhibit the production of platelets.
PCT/US2000/017698 1999-06-28 2000-06-28 Secreted alpha-helical protein-36 WO2001000664A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002415095A CA2415095A1 (en) 1999-06-28 2000-06-28 Secreted alpha-helical protein-36
AU58953/00A AU5895300A (en) 1999-06-28 2000-06-28 Secreted alpha-helical protein-36

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34315299A 1999-06-28 1999-06-28
US09/343,152 1999-06-28

Publications (2)

Publication Number Publication Date
WO2001000664A2 WO2001000664A2 (en) 2001-01-04
WO2001000664A3 true WO2001000664A3 (en) 2001-05-03

Family

ID=23344916

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/017698 WO2001000664A2 (en) 1999-06-28 2000-06-28 Secreted alpha-helical protein-36

Country Status (3)

Country Link
AU (1) AU5895300A (en)
CA (1) CA2415095A1 (en)
WO (1) WO2001000664A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013032908B1 (en) 2011-06-20 2023-01-10 The Aes Corporation APPARATUS AND METHOD FOR CONTROLLING POWER SERVICE EQUIPMENT CONNECTED TO AN ELECTRICAL POWER NETWORK AND READABLE STORAGE MEDIA

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 13 October 1997 (1997-10-13), M.S.H. KO ET AL: "Mus musculus 3.5-dpc blastocyst cDNA 3'-end sequence", XP002158473 *
DATABASE EMBL 18 September 1997 (1997-09-18), M. MARRA ET AL: "The WashU-HHMI mouse EST project", XP002158476 *
DATABASE EMBL 28 January 1998 (1998-01-28), M. MARRA ET AL: "The WashU-HHMI mouse EST project. vv45g03.r1 Soares 2NbMT musculus cDNA clone IMAGE:1225396 5', mRNA sequence", XP002158470 *
DATABASE EMBL 28 June 1999 (1999-06-28), M.YE ET AL: "Human HSPCmRNA, complete cds", XP002158469 *
DATABASE EMBL 29 November 1996 (1996-11-29), L. HILLIER ET AL: "zn41a02.r1 Stratagene endothelial cell 937223 Homo sapiens cDNA clone IMAGE:549962 5', mRNA sequence", XP002158471 *
L. HILLIER ET AL: "Generation and analysis of 280,000 human expressed sequence tags", GENOME RESEARCH, vol. 6, no. 9, 1996, pages 807 - 828, XP000914615 *
UNPUBLISHED *

Also Published As

Publication number Publication date
AU5895300A (en) 2001-01-31
WO2001000664A2 (en) 2001-01-04
CA2415095A1 (en) 2001-01-04

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