ES2150937T3 - Autotaxina: proteina estimulante de la motilidad util en el diagnostico y terapia del cancer. - Google Patents

Autotaxina: proteina estimulante de la motilidad util en el diagnostico y terapia del cancer.

Info

Publication number
ES2150937T3
ES2150937T3 ES93903044T ES93903044T ES2150937T3 ES 2150937 T3 ES2150937 T3 ES 2150937T3 ES 93903044 T ES93903044 T ES 93903044T ES 93903044 T ES93903044 T ES 93903044T ES 2150937 T3 ES2150937 T3 ES 2150937T3
Authority
ES
Spain
Prior art keywords
autotaxin
motility
diagnosis
useful
cancer therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93903044T
Other languages
English (en)
Inventor
Mary Stracke
Lance A Liotta
Elliott Schiffmann
Henry Krutzsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Application granted granted Critical
Publication of ES2150937T3 publication Critical patent/ES2150937T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE EN GENERAL A LA AUTOTAXINA. EN PARTICULAR, LA PRESENTE INVENCION SE REFIERE A UNA AUTOTAXINA CODIFICANDO EL SEGMENTO DEL DNA (CUALQUIERA DE LA CLASE DE ACIDOS NUCLEICOS QUE CONTIENE DEOXIRRIBOSA); MOLECULAS DEL DNA RECOMBINANTE CONTENIENDO EL SEGMENTO DEL DNA; CELULAS CONTENIENDO LA MOLECULA DEL DNA RECOMBINANTE; UN METODO DE PRODUCIR "AUTOTAXIN"; Y ANTICUERPOS PARA LA "AUTOTAXIN".
ES93903044T 1992-01-17 1993-01-15 Autotaxina: proteina estimulante de la motilidad util en el diagnostico y terapia del cancer. Expired - Lifetime ES2150937T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/822,043 US5449753A (en) 1992-01-17 1992-01-17 Autotaxin: motility stimulating protein useful in cancer diagnosis

Publications (1)

Publication Number Publication Date
ES2150937T3 true ES2150937T3 (es) 2000-12-16

Family

ID=25234963

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93903044T Expired - Lifetime ES2150937T3 (es) 1992-01-17 1993-01-15 Autotaxina: proteina estimulante de la motilidad util en el diagnostico y terapia del cancer.

Country Status (12)

Country Link
US (1) US5449753A (es)
EP (1) EP0629238B1 (es)
JP (1) JPH07505050A (es)
AT (1) ATE195342T1 (es)
AU (1) AU675927B2 (es)
CA (1) CA2128215C (es)
DE (1) DE69329190T2 (es)
DK (1) DK0629238T3 (es)
ES (1) ES2150937T3 (es)
GR (1) GR3034725T3 (es)
PT (1) PT629238E (es)
WO (1) WO1993014202A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731167A (en) * 1992-01-17 1998-03-24 The United States Of America As Represented By The Department Of Health And Human Services Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy
US20030153730A1 (en) 1992-01-17 2003-08-14 Mary Stracke Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy
WO2001074897A2 (en) * 2000-04-03 2001-10-11 Curagen Corporation Protein amf-1 to amf-10 and nucleic acids encoding the same
US20030065140A1 (en) * 2000-04-03 2003-04-03 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
WO2002084284A2 (en) * 2001-04-12 2002-10-24 Imperial College Innovations Limited Diagnosis and treatment of cancer:ii
JPWO2003031615A1 (ja) * 2001-10-04 2005-01-27 株式会社アプロサイエンス リゾホスファチジン酸合成酵素阻害物質
CN106970220A (zh) 2006-08-03 2017-07-21 国立大学法人东京大学 天然形式人自分泌运动因子特异的抗体、其筛选方法以及检测试剂
EP2162747B1 (en) * 2007-06-20 2014-04-30 Galapagos N.V. Molecular targets and methods to identify compounds for treating bone and joint degenerative diseases
JP5560608B2 (ja) * 2009-08-18 2014-07-30 東ソー株式会社 オートタキシンの精製方法
JP5700461B2 (ja) * 2013-03-08 2015-04-15 国立大学法人 東京大学 オートタキシン測定による妊娠および妊娠高血圧症候群の検査方法および検査薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0362278A4 (en) * 1987-06-05 1990-05-14 Us Health FACTORS OF AUTOCRINE MOTILITY IN THE DIAGNOSIS AND TREATMENT OF CANCER.
US5003047A (en) * 1989-01-10 1991-03-26 Massachusetts Institute Of Technology Method for purifying biologically active ligate
US5382521A (en) * 1992-07-14 1995-01-17 Michigan Cancer Foundation Method of determining metastatic potential of bladder tumor cells

Also Published As

Publication number Publication date
CA2128215A1 (en) 1993-07-22
AU675927B2 (en) 1997-02-27
US5449753A (en) 1995-09-12
DE69329190D1 (de) 2000-09-14
JPH07505050A (ja) 1995-06-08
CA2128215C (en) 2005-05-03
EP0629238A1 (en) 1994-12-21
AU3439893A (en) 1993-08-03
GR3034725T3 (en) 2001-01-31
PT629238E (pt) 2001-01-31
EP0629238B1 (en) 2000-08-09
DK0629238T3 (da) 2000-12-18
ATE195342T1 (de) 2000-08-15
WO1993014202A1 (en) 1993-07-22
DE69329190T2 (de) 2001-05-23

Similar Documents

Publication Publication Date Title
DE69431834D1 (de) Für den vorläufer des für die tumorabstossung verantwortlichen antigens mage-3 kodierendes, isoliertes nukleinsäuremolekül und seine verwendung
BG100771A (en) Hematopoeic protein and ways and methods for its preparation
ATE365744T1 (de) Nukleinsäuremoleküle, proteine und peptide, die im zusammenhang stehen mit dickdarmzellen und dickdarm-krebszellen
DE69617440D1 (de) Isolierte nukleinsäuremoleküle, peptide die mit hla-a2 moleküle (mhc) komplexe bilden, sowie deren verwendungen
ES2054878T3 (es) Expresion de la proapolipoproteina a-i humana.
WO1995032221A3 (en) Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy
EA200001023A1 (ru) Специфическое в отношении fapa-(протеин альфа активации фибробласта) антитело с повышенной продуктивностью
DE3650266D1 (de) DNS-Sequenzen, rekombinante DNS-Moleküle und Verfahren zur Herstellung von "mullerian inhibiting substance"-ähnlichen Polypeptiden.
JPS55104887A (en) Rearranged dna molecule and method
ATE162532T1 (de) Merschliches cnp-gen und vorläufer protein
ATE189478T1 (de) Für die reinigung bestimmte klonierung von peptiden
DE69129989D1 (de) Arzneimittelzusammensetzung zur behandlung oder vorbeugung maligner tumore
PT93910A (pt) Prodesso para a preparacao de uma proteina heterologa mediante secrecao a partir de uma celula
ATE354638T1 (de) Menschlicher gewebsinhibitor von metalloproteinase-4
ES2150937T3 (es) Autotaxina: proteina estimulante de la motilidad util en el diagnostico y terapia del cancer.
ATE173023T1 (de) Dna-sequenzen kodierend für das polypeptid gelonin
ES2107422T3 (es) Moleculas de adn recombinante, huespedes, procedimientos y polipeptidos similares a proteinas portadoras de somatomedina humana.
DE69935220D1 (de) Von menschlichem tumor stammendes polypeptidhormon phosphatonin
MX24652A (es) Compuestos de adn recombinante, vectores para la expresion de formas zimogenas de proteina c humana, celulas huesped transformadas y metodo para la prduccion recombinante de formas zimogenas de la proteina c humana.
FI970979A0 (fi) Muokatut ihmisen C3-proteiinit
ATE285416T1 (de) Expression und reinigung von kloniertem humanen alpha-fetoprotein
DE69125381D1 (de) Proteinstruktur des pflanzlichen toxins gelonin
EE05293B1 (et) RG1 polpeptiidiga seonduv antikeha, seda h?lmav immunkonjugaat ja nende kasutamine
ATE115409T1 (de) Glykoprotein-hormonrezeptor-moleküle.
EP0369816A3 (en) Monoclonal antibodies specific for human polymorphic epithelial mucin

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 629238

Country of ref document: ES