ATE285416T1 - Expression und reinigung von kloniertem humanen alpha-fetoprotein - Google Patents
Expression und reinigung von kloniertem humanen alpha-fetoproteinInfo
- Publication number
- ATE285416T1 ATE285416T1 AT93915109T AT93915109T ATE285416T1 AT E285416 T1 ATE285416 T1 AT E285416T1 AT 93915109 T AT93915109 T AT 93915109T AT 93915109 T AT93915109 T AT 93915109T AT E285416 T1 ATE285416 T1 AT E285416T1
- Authority
- AT
- Austria
- Prior art keywords
- human alpha
- fetoprotein
- expression
- purification
- cloned human
- Prior art date
Links
- 101000827785 Homo sapiens Alpha-fetoprotein Proteins 0.000 title abstract 4
- 101000848653 Homo sapiens Tripartite motif-containing protein 26 Proteins 0.000 title abstract 4
- 102000046101 human AFP Human genes 0.000 title abstract 4
- 238000000746 purification Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 102000013529 alpha-Fetoproteins Human genes 0.000 abstract 1
- 108010026331 alpha-Fetoproteins Proteins 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000001236 prokaryotic cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4715—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Pregnancy & Childbirth (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gynecology & Obstetrics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76743591A | 1991-09-27 | 1991-09-27 | |
| PCT/US1992/008317 WO1994010199A1 (en) | 1991-09-27 | 1992-10-30 | Expression and purification of cloned human alpha-fetoprotein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285416T1 true ATE285416T1 (de) | 2005-01-15 |
Family
ID=26785055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93915109T ATE285416T1 (de) | 1991-09-27 | 1992-10-30 | Expression und reinigung von kloniertem humanen alpha-fetoprotein |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5384250A (de) |
| EP (1) | EP0749441B1 (de) |
| JP (1) | JPH08511677A (de) |
| AT (1) | ATE285416T1 (de) |
| CA (1) | CA2120131A1 (de) |
| DE (1) | DE69233463T2 (de) |
| ES (1) | ES2235156T3 (de) |
| WO (1) | WO1994010199A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6288034B1 (en) | 1995-01-24 | 2001-09-11 | Martinex R & D Inc. | Recombinant human alpha-fetoprotein as an immunosuppressive agent |
| US5965528A (en) | 1991-09-27 | 1999-10-12 | Mcgill University | Recombinant human alph-fetoprotein as an immunosuppressive agent |
| US6331611B1 (en) | 1991-09-27 | 2001-12-18 | Mcgill University | Expression and purification of cloned human alpha-fetoprotein |
| US5674842A (en) * | 1994-10-26 | 1997-10-07 | Health Research, Incorporated | Growth inhibitory peptide |
| US7101837B1 (en) | 1995-01-24 | 2006-09-05 | Martinex R & D Inc. | Recombinant human alpha-fetoprotein as a cell proliferative agent |
| EP0805687A4 (de) * | 1995-01-24 | 2000-05-31 | Robert A Murgita | Rekombinantes humanes alpha-fetoprotein und seine verwendungen |
| US6534479B1 (en) | 1995-01-24 | 2003-03-18 | Martinex R & D Inc. | Recombinant alpha-fetoprotein hybrid cytotoxins for treating and diagnosing cancers |
| US5866329A (en) * | 1995-09-27 | 1999-02-02 | Demetriou; Achilles A. | Method and probe for detection of gene associated with liver neoplastic disease |
| US6087334A (en) * | 1998-08-21 | 2000-07-11 | Amylin Pharmaceuticals, Inc. | Anti-diabetic peptides |
| US7208576B2 (en) | 1999-01-06 | 2007-04-24 | Merrimack Pharmaceuticals, Inc. | Non-glycosylated human alpha-fetoprotein, methods of production, and uses thereof |
| WO2000040693A2 (en) * | 1999-01-06 | 2000-07-13 | Atlantic Biopharmaceuticals, Inc. | Expression of secreted human alpha-fetoprotein in transgenic animals |
| CN100494362C (zh) * | 2001-08-07 | 2009-06-03 | 诺维信公司 | 碳水化合物和多元醇用于溶解蛋白晶体 |
| EA011606B1 (ru) * | 2004-07-14 | 2009-04-28 | Эдуард Борисович Татулов | Способы получения и применения рекомбинантного альфа-фетопротеина |
| CA2673398A1 (en) * | 2006-12-19 | 2008-07-03 | Merrimack Pharmaceuticals, Inc. | Coadministration of alpha-fetoprotein and an immunomodulatory agent to treat multiple sclerosis |
| US20100150915A1 (en) * | 2007-02-20 | 2010-06-17 | Stewart Edward J | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist |
| US20100304873A1 (en) * | 2009-05-28 | 2010-12-02 | Lipa Markowitz | Bowling Ball and Football Game Controller |
| CN105732795A (zh) * | 2016-03-21 | 2016-07-06 | 海南医学院 | 一种获得人类甲胎蛋白的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH025866A (ja) * | 1988-06-27 | 1990-01-10 | Kansai Shin Gijutsu Kenkyusho:Kk | ヒトアルファフェトプロテインドメインｉ遺伝子、対応プラスミド組換体、対応形質転換体、該ドメインｉの製造法及び製造された該ドメインｉ |
| US5206153A (en) * | 1990-06-27 | 1993-04-27 | Snow Brand Milk Products Co., Ltd. | Method of producing human α-fetoprotein and product produced thereby |
-
1992
- 1992-09-28 CA CA002120131A patent/CA2120131A1/en not_active Abandoned
- 1992-10-30 WO PCT/US1992/008317 patent/WO1994010199A1/en not_active Ceased
- 1992-10-30 ES ES93915109T patent/ES2235156T3/es not_active Expired - Lifetime
- 1992-10-30 AT AT93915109T patent/ATE285416T1/de not_active IP Right Cessation
- 1992-10-30 DE DE69233463T patent/DE69233463T2/de not_active Expired - Fee Related
- 1992-10-30 JP JP6507567A patent/JPH08511677A/ja active Pending
- 1992-10-30 EP EP93915109A patent/EP0749441B1/de not_active Expired - Lifetime
-
1993
- 1993-10-08 US US08/133,773 patent/US5384250A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0749441A4 (de) | 1998-12-30 |
| EP0749441A1 (de) | 1996-12-27 |
| DE69233463D1 (de) | 2005-01-27 |
| US5384250A (en) | 1995-01-24 |
| CA2120131A1 (en) | 1994-05-11 |
| EP0749441B1 (de) | 2004-12-22 |
| WO1994010199A1 (en) | 1994-05-11 |
| DE69233463T2 (de) | 2005-12-22 |
| JPH08511677A (ja) | 1996-12-10 |
| ES2235156T3 (es) | 2005-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0749441 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |