DE69329190T2 - Autotaxin : ein das selbständige zellbewegungsvermögen stimulierendes protein nützlich in der krebs-diagnostik und therapie - Google Patents

Autotaxin : ein das selbständige zellbewegungsvermögen stimulierendes protein nützlich in der krebs-diagnostik und therapie

Info

Publication number
DE69329190T2
DE69329190T2 DE69329190T DE69329190T DE69329190T2 DE 69329190 T2 DE69329190 T2 DE 69329190T2 DE 69329190 T DE69329190 T DE 69329190T DE 69329190 T DE69329190 T DE 69329190T DE 69329190 T2 DE69329190 T2 DE 69329190T2
Authority
DE
Germany
Prior art keywords
autotaxin
therapy
cell movement
cancer diagnostics
protein independent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69329190T
Other languages
English (en)
Other versions
DE69329190D1 (de
Inventor
Mary Stracke
A Liotta
Elliott Schiffmann
Henry Krutzsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institutes of Health NIH
Original Assignee
National Institutes of Health NIH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Institutes of Health NIH filed Critical National Institutes of Health NIH
Publication of DE69329190D1 publication Critical patent/DE69329190D1/de
Application granted granted Critical
Publication of DE69329190T2 publication Critical patent/DE69329190T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69329190T 1992-01-17 1993-01-15 Autotaxin : ein das selbständige zellbewegungsvermögen stimulierendes protein nützlich in der krebs-diagnostik und therapie Expired - Lifetime DE69329190T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/822,043 US5449753A (en) 1992-01-17 1992-01-17 Autotaxin: motility stimulating protein useful in cancer diagnosis
PCT/US1993/000181 WO1993014202A1 (en) 1992-01-17 1993-01-15 Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy

Publications (2)

Publication Number Publication Date
DE69329190D1 DE69329190D1 (de) 2000-09-14
DE69329190T2 true DE69329190T2 (de) 2001-05-23

Family

ID=25234963

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69329190T Expired - Lifetime DE69329190T2 (de) 1992-01-17 1993-01-15 Autotaxin : ein das selbständige zellbewegungsvermögen stimulierendes protein nützlich in der krebs-diagnostik und therapie

Country Status (12)

Country Link
US (1) US5449753A (de)
EP (1) EP0629238B1 (de)
JP (1) JPH07505050A (de)
AT (1) ATE195342T1 (de)
AU (1) AU675927B2 (de)
CA (1) CA2128215C (de)
DE (1) DE69329190T2 (de)
DK (1) DK0629238T3 (de)
ES (1) ES2150937T3 (de)
GR (1) GR3034725T3 (de)
PT (1) PT629238E (de)
WO (1) WO1993014202A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030153730A1 (en) 1992-01-17 2003-08-14 Mary Stracke Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy
US5731167A (en) * 1992-01-17 1998-03-24 The United States Of America As Represented By The Department Of Health And Human Services Autotaxin: motility stimulating protein useful in cancer diagnosis and therapy
US20030065140A1 (en) * 2000-04-03 2003-04-03 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
WO2001074897A2 (en) * 2000-04-03 2001-10-11 Curagen Corporation Protein amf-1 to amf-10 and nucleic acids encoding the same
AU2002251286A1 (en) * 2001-04-12 2002-10-28 Imperial College Innovations Limited Diagnosis and treatment of cancer:ii
WO2003031615A1 (fr) * 2001-10-04 2003-04-17 Apro Life Science Institute, Inc. Inhibiteur de l'acide lysophosphatidique synthase
EP2048501B1 (de) * 2006-08-03 2016-03-09 The University of Tokyo Gegen intaktes menschliches autotaxin spezifischer antikörper, verfahren zum screening davon sowie verfahren und reagens zur untersuchung eines bösartigen lymphoms mittels autotaxin-tests
US8637257B2 (en) * 2007-06-20 2014-01-28 Galapagos Nv Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases
JP5560608B2 (ja) * 2009-08-18 2014-07-30 東ソー株式会社 オートタキシンの精製方法
JP5700461B2 (ja) * 2013-03-08 2015-04-15 国立大学法人 東京大学 オートタキシン測定による妊娠および妊娠高血圧症候群の検査方法および検査薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988009797A1 (en) * 1987-06-05 1988-12-15 The United States Of America, As Represented By Th Autocrine motility factors in cancer diagnosis and management
US5003047A (en) * 1989-01-10 1991-03-26 Massachusetts Institute Of Technology Method for purifying biologically active ligate
US5382521A (en) * 1992-07-14 1995-01-17 Michigan Cancer Foundation Method of determining metastatic potential of bladder tumor cells

Also Published As

Publication number Publication date
ATE195342T1 (de) 2000-08-15
ES2150937T3 (es) 2000-12-16
AU3439893A (en) 1993-08-03
AU675927B2 (en) 1997-02-27
WO1993014202A1 (en) 1993-07-22
PT629238E (pt) 2001-01-31
GR3034725T3 (en) 2001-01-31
CA2128215C (en) 2005-05-03
DE69329190D1 (de) 2000-09-14
JPH07505050A (ja) 1995-06-08
CA2128215A1 (en) 1993-07-22
US5449753A (en) 1995-09-12
EP0629238A1 (de) 1994-12-21
EP0629238B1 (de) 2000-08-09
DK0629238T3 (da) 2000-12-18

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