DK0832082T3 - N-heteroaryl-pyridinsulfonamidderivater og deres anvendelse som endotelinantagonister - Google Patents

N-heteroaryl-pyridinsulfonamidderivater og deres anvendelse som endotelinantagonister

Info

Publication number
DK0832082T3
DK0832082T3 DK96919941T DK96919941T DK0832082T3 DK 0832082 T3 DK0832082 T3 DK 0832082T3 DK 96919941 T DK96919941 T DK 96919941T DK 96919941 T DK96919941 T DK 96919941T DK 0832082 T3 DK0832082 T3 DK 0832082T3
Authority
DK
Denmark
Prior art keywords
heteroaryl
sulfonamide derivatives
endothelin antagonists
pyridine sulfonamide
pyridine
Prior art date
Application number
DK96919941T
Other languages
Danish (da)
English (en)
Inventor
Robert Hugh Bradbury
Roger John Butlin
Roger James
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26307176&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0832082(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9511507.7A external-priority patent/GB9511507D0/en
Priority claimed from GBGB9519666.3A external-priority patent/GB9519666D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK0832082T3 publication Critical patent/DK0832082T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
DK96919941T 1995-06-07 1996-06-03 N-heteroaryl-pyridinsulfonamidderivater og deres anvendelse som endotelinantagonister DK0832082T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9511507.7A GB9511507D0 (en) 1995-06-07 1995-06-07 Heterocyclic compounds
GBGB9519666.3A GB9519666D0 (en) 1995-09-27 1995-09-27 Heterocyclic derivatives
PCT/GB1996/001295 WO1996040681A1 (en) 1995-06-07 1996-06-03 N-heteroaryl-pyridinesulfonamide derivatives and their use as endothelin antagonists

Publications (1)

Publication Number Publication Date
DK0832082T3 true DK0832082T3 (da) 2002-05-21

Family

ID=26307176

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96919941T DK0832082T3 (da) 1995-06-07 1996-06-03 N-heteroaryl-pyridinsulfonamidderivater og deres anvendelse som endotelinantagonister

Country Status (32)

Country Link
US (3) US5866568A (hu)
EP (1) EP0832082B1 (hu)
JP (1) JP3193058B2 (hu)
KR (1) KR100451523B1 (hu)
CN (1) CN1097051C (hu)
AR (1) AR003132A1 (hu)
AT (1) ATE209200T1 (hu)
AU (1) AU715041B2 (hu)
BR (1) BR9608611A (hu)
CA (1) CA2219742C (hu)
CZ (1) CZ289387B6 (hu)
DE (1) DE69617236T2 (hu)
DK (1) DK0832082T3 (hu)
EG (1) EG25227A (hu)
ES (1) ES2168487T3 (hu)
GE (1) GEP20053470B (hu)
HK (1) HK1005801A1 (hu)
HR (1) HRP960272B1 (hu)
HU (1) HUP9802300A3 (hu)
IL (1) IL122464A (hu)
MX (1) MX9709521A (hu)
MY (1) MY114926A (hu)
NO (1) NO314503B1 (hu)
NZ (1) NZ308619A (hu)
PL (1) PL187897B1 (hu)
PT (1) PT832082E (hu)
RU (1) RU2172738C2 (hu)
SK (1) SK282338B6 (hu)
TR (1) TR199701502T1 (hu)
TW (1) TW340845B (hu)
UA (1) UA58494C2 (hu)
WO (1) WO1996040681A1 (hu)

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US6858592B2 (en) 2001-06-29 2005-02-22 Genzyme Corporation Aryl boronic acids for treating obesity
US7041280B2 (en) 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
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US7169805B2 (en) * 2003-05-28 2007-01-30 Nicox S.A. Captopril derivatives
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HUE039416T2 (hu) 2008-06-19 2018-12-28 Takeda Pharmaceuticals Co Heterociklusos vegyület és ennek alkalmazása
KR101677778B1 (ko) * 2009-02-06 2016-11-18 니뽄 신야쿠 가부시키가이샤 아미노피라진 유도체 및 의약
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TW202317555A (zh) 2021-06-22 2023-05-01 日商亞克醫藥股份有限公司 化合物、內皮素a受體拮抗劑及醫藥組合物
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Also Published As

Publication number Publication date
CZ388797A3 (cs) 1998-03-18
MX9709521A (es) 1998-03-31
NZ308619A (en) 2000-01-28
CA2219742A1 (en) 1996-12-19
DE69617236T2 (de) 2002-07-11
WO1996040681A1 (en) 1996-12-19
CN1097051C (zh) 2002-12-25
TR199701502T1 (xx) 1998-03-21
HRP960272B1 (en) 2006-06-30
HUP9802300A3 (en) 2002-02-28
CA2219742C (en) 2007-01-16
KR19990022327A (ko) 1999-03-25
IL122464A (en) 2002-05-23
ATE209200T1 (de) 2001-12-15
JP3193058B2 (ja) 2001-07-30
MY114926A (en) 2003-02-28
DE69617236D1 (de) 2002-01-03
NO975700L (no) 1997-12-05
PL187897B1 (pl) 2004-10-29
IL122464A0 (en) 1998-09-15
NO314503B1 (no) 2003-03-31
JPH11509175A (ja) 1999-08-17
RU2172738C2 (ru) 2001-08-27
SK168097A3 (en) 1998-05-06
UA58494C2 (uk) 2003-08-15
HUP9802300A2 (hu) 1999-10-28
KR100451523B1 (ko) 2004-12-03
EP0832082A1 (en) 1998-04-01
US6258817B1 (en) 2001-07-10
AU715041B2 (en) 2000-01-13
CN1192739A (zh) 1998-09-09
TW340845B (en) 1998-09-21
NO975700D0 (no) 1997-12-05
CZ289387B6 (cs) 2002-01-16
PL324660A1 (en) 1998-06-08
AU5840396A (en) 1996-12-30
AR003132A1 (es) 1998-07-08
BR9608611A (pt) 1999-05-11
HRP960272A2 (en) 1997-08-31
EG25227A (en) 2011-11-17
US5866568A (en) 1999-02-02
ES2168487T3 (es) 2002-06-16
GEP20053470B (en) 2005-02-25
SK282338B6 (sk) 2002-01-07
PT832082E (pt) 2002-04-29
US6060475A (en) 2000-05-09
EP0832082B1 (en) 2001-11-21
HK1005801A1 (en) 1999-01-29

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