DK0776904T3 - Fremgangsmåde til fremstilling af steroidderivatketal - Google Patents
Fremgangsmåde til fremstilling af steroidderivatketalInfo
- Publication number
- DK0776904T3 DK0776904T3 DK96203367T DK96203367T DK0776904T3 DK 0776904 T3 DK0776904 T3 DK 0776904T3 DK 96203367 T DK96203367 T DK 96203367T DK 96203367 T DK96203367 T DK 96203367T DK 0776904 T3 DK0776904 T3 DK 0776904T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- steroid derivative
- ketal
- derivative ketal
- steroid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
- C07J75/005—Preparation of steroids by cyclization of non-steroid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1001787 | 1995-11-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0776904T3 true DK0776904T3 (da) | 2000-07-31 |
Family
ID=19761947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96203367T DK0776904T3 (da) | 1995-11-30 | 1996-11-28 | Fremgangsmåde til fremstilling af steroidderivatketal |
Country Status (25)
Country | Link |
---|---|
US (2) | US5955622A (ru) |
EP (1) | EP0776904B1 (ru) |
JP (1) | JP3984315B2 (ru) |
KR (1) | KR100430312B1 (ru) |
CN (1) | CN1152847C (ru) |
AR (1) | AR004813A1 (ru) |
AT (1) | ATE190314T1 (ru) |
AU (1) | AU713688B2 (ru) |
CA (1) | CA2191397C (ru) |
CZ (1) | CZ293396B6 (ru) |
DE (1) | DE69606957T2 (ru) |
DK (1) | DK0776904T3 (ru) |
ES (1) | ES2145971T3 (ru) |
GR (1) | GR3033527T3 (ru) |
HU (1) | HUP9603296A3 (ru) |
IL (1) | IL119649A (ru) |
IN (1) | IN182807B (ru) |
MX (1) | MX9605981A (ru) |
NO (1) | NO307887B1 (ru) |
NZ (1) | NZ299836A (ru) |
PL (1) | PL185112B1 (ru) |
PT (1) | PT776904E (ru) |
RU (1) | RU2165430C2 (ru) |
TR (1) | TR199600944A1 (ru) |
ZA (1) | ZA969778B (ru) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200611909A (en) | 2004-08-04 | 2006-04-16 | Akzo Nobel Nv | Process for the preparation 2-substituted-derivatives of estrone and estradiol |
TW200613316A (en) | 2004-08-26 | 2006-05-01 | Akzo Nobel Nv | Process for the preparation of estrone and/or estradiol-derivates |
HUP0501132A2 (en) | 2005-12-05 | 2007-06-28 | Richter Gedeon Nyrt | 17-alpha-cyanomethyl-17betha-hydroxyestra-4,9-diene-3-one of high purity and process for its production |
ITMI20062504A1 (it) | 2006-12-22 | 2008-06-23 | Antibioticos Spa | Procedimento per la preparazione di 17alfa-cianometil-17beta-idrossi steroidi |
US8673968B2 (en) * | 2009-04-06 | 2014-03-18 | Evestra, Inc. | Progesterone antagonists |
WO2011132045A2 (en) | 2010-04-20 | 2011-10-27 | Lupin Limited | Process for the preparation of dienogest substantially free of impurities |
CN101863947A (zh) * | 2010-06-29 | 2010-10-20 | 沈阳药科大学 | 一种地诺孕素的合成方法 |
CN102718828A (zh) * | 2011-03-30 | 2012-10-10 | 西藏海思科药业集团股份有限公司 | 一种地诺孕素的制备方法 |
US9096641B2 (en) | 2013-06-05 | 2015-08-04 | Evestra, Inc. | Imidazolyl progesterone antagonists |
CN104497088B (zh) * | 2014-12-30 | 2016-08-24 | 湖南新合新生物医药有限公司 | 19-去甲-4-雄甾烯-3,17-二酮的制备方法 |
CN108997463B (zh) * | 2018-08-09 | 2021-05-14 | 四川理工学院 | 一种雌甾-4,9-二烯-3,17-二酮制备方法 |
CN112409434B (zh) * | 2020-11-27 | 2021-10-26 | 厦门欧瑞捷生物科技有限公司 | 一种去氢孕酮的合成方法 |
CN113861158B (zh) * | 2021-11-22 | 2023-02-10 | 湖南新合新生物医药有限公司 | 一种合成甲基双烯双酮关键中间体的方法 |
CN114409717B (zh) * | 2021-12-17 | 2023-03-17 | 湖南科益新生物医药有限公司 | 替勃龙中间体醚化物和替勃龙的制备方法 |
CN114456223B (zh) * | 2022-01-24 | 2023-07-21 | 湖南科益新生物医药有限公司 | 3-缩酮的合成方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE632347A (ru) * | ||||
DE296931C (ru) | 1915-11-05 | 1917-03-06 | ||
BE657262A (ru) * | 1962-03-06 | |||
NL127071C (ru) * | 1964-12-31 | |||
FR2201287A1 (en) * | 1972-09-27 | 1974-04-26 | Roussel Uclaf | Epoxidation using hexafluoroacetone hydroperoxide - for treatment of unsatd. cyclic cpds esp steroids |
DE3113053A1 (de) * | 1981-04-01 | 1982-10-21 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur herstellung eines tricyclischen steroid-abbauprodukts |
US4400524A (en) * | 1981-07-28 | 1983-08-23 | The Upjohn Company | Grignard reagents prepared from 5-halopentan-2-one propylene ketals |
DE3208432A1 (de) * | 1982-03-09 | 1983-09-15 | The Upjohn Co., 49001 Kalamazoo, Mich. | Verfahren zur herstellung von 19-norandrostendion, zwischenprodukt des 19-norandrostendions und verfahren zu seiner herstellung |
HU201091B (en) * | 1985-12-26 | 1990-09-28 | Mitsubishi Chem Ind | Process for producing gonatriene derivatives and pharmaceutical compositions comprising same |
NZ232422A (en) * | 1989-02-16 | 1992-11-25 | Merck & Co Inc | 13-ketal milbemycin derivatives and parasiticides |
US5438134A (en) * | 1990-07-09 | 1995-08-01 | Jenapharm Gmbh | Process for the production of unsaturated 17 α-cyanomethyl-17 β-h |
CA2100514C (en) * | 1992-07-29 | 2005-03-29 | Johannes A. M. Hamersma | 17-spiromethylene steroids |
EP0712311B1 (en) * | 1993-08-04 | 1998-10-07 | Akzo Nobel N.V. | Antiglucocorticoid steroids for the treatment of anxiety disorders |
-
1996
- 1996-11-19 IL IL11964996A patent/IL119649A/en not_active IP Right Cessation
- 1996-11-20 IN IN2069MA1996 patent/IN182807B/en unknown
- 1996-11-21 ZA ZA969778A patent/ZA969778B/xx unknown
- 1996-11-25 KR KR1019960057104A patent/KR100430312B1/ko not_active IP Right Cessation
- 1996-11-27 NZ NZ299836A patent/NZ299836A/en unknown
- 1996-11-27 TR TR96/00944A patent/TR199600944A1/xx unknown
- 1996-11-27 CA CA002191397A patent/CA2191397C/en not_active Expired - Fee Related
- 1996-11-28 PT PT96203367T patent/PT776904E/pt unknown
- 1996-11-28 ES ES96203367T patent/ES2145971T3/es not_active Expired - Lifetime
- 1996-11-28 AT AT96203367T patent/ATE190314T1/de not_active IP Right Cessation
- 1996-11-28 DE DE69606957T patent/DE69606957T2/de not_active Expired - Lifetime
- 1996-11-28 EP EP96203367A patent/EP0776904B1/en not_active Expired - Lifetime
- 1996-11-28 AU AU74041/96A patent/AU713688B2/en not_active Ceased
- 1996-11-28 PL PL96317248A patent/PL185112B1/pl not_active IP Right Cessation
- 1996-11-28 DK DK96203367T patent/DK0776904T3/da active
- 1996-11-29 MX MX9605981A patent/MX9605981A/es not_active IP Right Cessation
- 1996-11-29 CN CNB961217901A patent/CN1152847C/zh not_active Expired - Lifetime
- 1996-11-29 JP JP32007996A patent/JP3984315B2/ja not_active Expired - Fee Related
- 1996-11-29 AR ARP960105421A patent/AR004813A1/es active IP Right Grant
- 1996-11-29 RU RU96123242/04A patent/RU2165430C2/ru not_active IP Right Cessation
- 1996-11-29 CZ CZ19963504A patent/CZ293396B6/cs not_active IP Right Cessation
- 1996-11-29 NO NO965113A patent/NO307887B1/no not_active IP Right Cessation
- 1996-11-29 HU HU9603296A patent/HUP9603296A3/hu unknown
-
1998
- 1998-08-05 US US09/129,250 patent/US5955622A/en not_active Expired - Lifetime
-
1999
- 1999-01-04 US US09/224,987 patent/US6005124A/en not_active Expired - Fee Related
-
2000
- 2000-05-29 GR GR20000401218T patent/GR3033527T3/el not_active IP Right Cessation
Also Published As
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