HUP9603296A3 - New method for the preparation of steroid derivative ketal - Google Patents

New method for the preparation of steroid derivative ketal

Info

Publication number
HUP9603296A3
HUP9603296A3 HU9603296A HUP9603296A HUP9603296A3 HU P9603296 A3 HUP9603296 A3 HU P9603296A3 HU 9603296 A HU9603296 A HU 9603296A HU P9603296 A HUP9603296 A HU P9603296A HU P9603296 A3 HUP9603296 A3 HU P9603296A3
Authority
HU
Hungary
Prior art keywords
preparation
new method
steroid derivative
ketal
derivative ketal
Prior art date
Application number
HU9603296A
Other languages
Hungarian (hu)
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of HU9603296D0 publication Critical patent/HU9603296D0/en
Publication of HUP9603296A2 publication Critical patent/HUP9603296A2/en
Publication of HUP9603296A3 publication Critical patent/HUP9603296A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C07J75/005—Preparation of steroids by cyclization of non-steroid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
HU9603296A 1995-11-30 1996-11-29 New method for the preparation of steroid derivative ketal HUP9603296A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL1001787 1995-11-30

Publications (3)

Publication Number Publication Date
HU9603296D0 HU9603296D0 (en) 1997-01-28
HUP9603296A2 HUP9603296A2 (en) 1997-08-28
HUP9603296A3 true HUP9603296A3 (en) 1998-07-28

Family

ID=19761947

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9603296A HUP9603296A3 (en) 1995-11-30 1996-11-29 New method for the preparation of steroid derivative ketal

Country Status (25)

Country Link
US (2) US5955622A (en)
EP (1) EP0776904B1 (en)
JP (1) JP3984315B2 (en)
KR (1) KR100430312B1 (en)
CN (1) CN1152847C (en)
AR (1) AR004813A1 (en)
AT (1) ATE190314T1 (en)
AU (1) AU713688B2 (en)
CA (1) CA2191397C (en)
CZ (1) CZ293396B6 (en)
DE (1) DE69606957T2 (en)
DK (1) DK0776904T3 (en)
ES (1) ES2145971T3 (en)
GR (1) GR3033527T3 (en)
HU (1) HUP9603296A3 (en)
IL (1) IL119649A (en)
IN (1) IN182807B (en)
MX (1) MX9605981A (en)
NO (1) NO307887B1 (en)
NZ (1) NZ299836A (en)
PL (1) PL185112B1 (en)
PT (1) PT776904E (en)
RU (1) RU2165430C2 (en)
TR (1) TR199600944A1 (en)
ZA (1) ZA969778B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200611909A (en) * 2004-08-04 2006-04-16 Akzo Nobel Nv Process for the preparation 2-substituted-derivatives of estrone and estradiol
TW200613316A (en) 2004-08-26 2006-05-01 Akzo Nobel Nv Process for the preparation of estrone and/or estradiol-derivates
HUP0501132A2 (en) 2005-12-05 2007-06-28 Richter Gedeon Nyrt 17-alpha-cyanomethyl-17betha-hydroxyestra-4,9-diene-3-one of high purity and process for its production
ITMI20062504A1 (en) 2006-12-22 2008-06-23 Antibioticos Spa PROCEDURE FOR THE PREPARATION OF STEROID 17ALPHA-CYANOMETHYL-17BETA-HYDROXIDE
US8673968B2 (en) * 2009-04-06 2014-03-18 Evestra, Inc. Progesterone antagonists
WO2011132045A2 (en) 2010-04-20 2011-10-27 Lupin Limited Process for the preparation of dienogest substantially free of impurities
CN101863947A (en) * 2010-06-29 2010-10-20 沈阳药科大学 Synthesis method of dienogest
CN102718828A (en) * 2011-03-30 2012-10-10 西藏海思科药业集团股份有限公司 Preparation method for dienogest
US9096641B2 (en) 2013-06-05 2015-08-04 Evestra, Inc. Imidazolyl progesterone antagonists
CN104497088B (en) * 2014-12-30 2016-08-24 湖南新合新生物医药有限公司 The preparation method of 19-nor--4-androstene-3,17-diketone
CN108997463B (en) * 2018-08-09 2021-05-14 四川理工学院 Preparation method of estra-4, 9-diene-3, 17-dione
CN112409434B (en) * 2020-11-27 2021-10-26 厦门欧瑞捷生物科技有限公司 Synthesis method of dehydroprogesterone
CN113861158B (en) * 2021-11-22 2023-02-10 湖南新合新生物医药有限公司 Method for synthesizing methyl diene diketone key intermediate
CN114409717B (en) * 2021-12-17 2023-03-17 湖南科益新生物医药有限公司 Tibolone intermediate etherate and preparation method of tibolone
CN114456223B (en) * 2022-01-24 2023-07-21 湖南科益新生物医药有限公司 Synthesis method of 3-ketal

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632347A (en) *
DE296931C (en) 1915-11-05 1917-03-06
NL122142C (en) * 1962-03-06
NL127071C (en) * 1964-12-31
FR2201287A1 (en) * 1972-09-27 1974-04-26 Roussel Uclaf Epoxidation using hexafluoroacetone hydroperoxide - for treatment of unsatd. cyclic cpds esp steroids
DE3113053A1 (en) * 1981-04-01 1982-10-21 Henkel KGaA, 4000 Düsseldorf METHOD FOR PRODUCING A TRICYCLIC STEROID DEGRADATION PRODUCT
US4400524A (en) * 1981-07-28 1983-08-23 The Upjohn Company Grignard reagents prepared from 5-halopentan-2-one propylene ketals
DE3208432A1 (en) * 1982-03-09 1983-09-15 The Upjohn Co., 49001 Kalamazoo, Mich. Process for the preparation of 19-norandrostenedione, intermediate of 19-norandrostenedione and processes for its preparation
HU201091B (en) * 1985-12-26 1990-09-28 Mitsubishi Chem Ind Process for producing gonatriene derivatives and pharmaceutical compositions comprising same
NZ232422A (en) * 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
CA2086919C (en) * 1990-07-09 1998-02-24 Gerhard Teichmuller Process for the production of unsaturated 17.alpha.-cyanomethyl -17.beta. hydroxy steroids
CA2100514C (en) * 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
US5741787A (en) * 1993-08-04 1998-04-21 Akzo Nobel N.V. Antiglucocorticoid steroids for the treatment of anxiety disorders

Also Published As

Publication number Publication date
NZ299836A (en) 1997-11-24
CZ293396B6 (en) 2004-04-14
EP0776904A2 (en) 1997-06-04
IL119649A0 (en) 1997-02-18
NO965113D0 (en) 1996-11-29
PL185112B1 (en) 2003-02-28
ATE190314T1 (en) 2000-03-15
IN182807B (en) 1999-04-24
CA2191397C (en) 2006-08-01
PT776904E (en) 2000-07-31
AR004813A1 (en) 1999-03-10
AU713688B2 (en) 1999-12-09
IL119649A (en) 2002-03-10
US5955622A (en) 1999-09-21
DK0776904T3 (en) 2000-07-31
US6005124A (en) 1999-12-21
ZA969778B (en) 1997-06-17
CN1152847C (en) 2004-06-09
HU9603296D0 (en) 1997-01-28
DE69606957T2 (en) 2000-10-05
RU2165430C2 (en) 2001-04-20
EP0776904B1 (en) 2000-03-08
KR100430312B1 (en) 2004-07-30
NO965113L (en) 1997-06-02
CA2191397A1 (en) 1997-05-31
CN1168876A (en) 1997-12-31
GR3033527T3 (en) 2000-09-29
JP3984315B2 (en) 2007-10-03
JPH09183792A (en) 1997-07-15
HUP9603296A2 (en) 1997-08-28
CZ350496A3 (en) 1998-03-18
EP0776904A3 (en) 1997-12-17
MX9605981A (en) 1998-04-30
TR199600944A1 (en) 1997-06-21
NO307887B1 (en) 2000-06-13
ES2145971T3 (en) 2000-07-16
DE69606957D1 (en) 2000-04-13
KR970027102A (en) 1997-06-24
PL317248A1 (en) 1997-06-09
AU7404196A (en) 1997-06-05

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: N.V. ORGANON, NL

Free format text: FORMER OWNER(S): AKZO NOBEL N.V., NL

FD9A Lapse of provisional protection due to non-payment of fees