DK0756484T3 - Vådgranuleringsformulering til diphosphonsyrer - Google Patents

Vådgranuleringsformulering til diphosphonsyrer

Info

Publication number
DK0756484T3
DK0756484T3 DK95917120T DK95917120T DK0756484T3 DK 0756484 T3 DK0756484 T3 DK 0756484T3 DK 95917120 T DK95917120 T DK 95917120T DK 95917120 T DK95917120 T DK 95917120T DK 0756484 T3 DK0756484 T3 DK 0756484T3
Authority
DK
Denmark
Prior art keywords
wet granulation
diphosphonic acids
binder
prepared
treatment
Prior art date
Application number
DK95917120T
Other languages
Danish (da)
English (en)
Inventor
Ashok V Katdare
Kenneth A Kramer
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22891482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0756484(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK0756484T3 publication Critical patent/DK0756484T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK95917120T 1994-04-29 1995-04-24 Vådgranuleringsformulering til diphosphonsyrer DK0756484T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23690494A 1994-04-29 1994-04-29
PCT/US1995/004965 WO1995029679A1 (en) 1994-04-29 1995-04-24 Wet granulation formulation for bisphosphonic acids

Publications (1)

Publication Number Publication Date
DK0756484T3 true DK0756484T3 (da) 2002-11-25

Family

ID=22891482

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95917120T DK0756484T3 (da) 1994-04-29 1995-04-24 Vådgranuleringsformulering til diphosphonsyrer

Country Status (33)

Country Link
EP (1) EP0756484B1 (bg)
JP (1) JP3838658B2 (bg)
KR (1) KR100390719B1 (bg)
CN (2) CN1147202A (bg)
AT (1) ATE225661T1 (bg)
AU (1) AU694217C (bg)
BG (1) BG62878B1 (bg)
CA (1) CA2188567C (bg)
CO (1) CO4560546A1 (bg)
CZ (1) CZ291574B6 (bg)
DE (1) DE69528525T2 (bg)
DK (1) DK0756484T3 (bg)
ES (1) ES2183873T3 (bg)
FI (1) FI118206B (bg)
HK (1) HK1009246A1 (bg)
HR (1) HRP950261B1 (bg)
HU (1) HUT76297A (bg)
IL (1) IL113465A (bg)
LV (1) LV13114B (bg)
MX (1) MX9605222A (bg)
MY (1) MY120491A (bg)
NO (1) NO964567L (bg)
NZ (1) NZ284719A (bg)
PL (1) PL316987A1 (bg)
PT (1) PT756484E (bg)
RU (1) RU2149003C1 (bg)
SA (1) SA95160013B1 (bg)
SK (1) SK283785B6 (bg)
TW (1) TW390813B (bg)
UA (1) UA44733C2 (bg)
WO (1) WO1995029679A1 (bg)
YU (1) YU49458B (bg)
ZA (1) ZA953437B (bg)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19615812A1 (de) * 1996-04-20 1997-10-23 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation
DE19719680A1 (de) 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
KR100400053B1 (ko) * 1997-06-11 2003-09-29 더 프록터 앤드 갬블 캄파니 향상된 상부 위장관 안전용 필름 피복 정제
IL121623A (en) * 1997-08-26 2000-06-29 Unipharm Ltd Process for the preparation of solid oral dosage forms comprising alendronic acid
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
EP0998933A1 (de) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Verfahren zur Herstellung von bisphosphonathaltigen pharmazeutischen Zusammensetzungen zur oralen Applikation
EP0998932A1 (de) 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
PL351674A1 (en) * 1999-05-21 2003-05-19 Novartis Ag Use of bisphosphonic acids for treating angiogenesis
PL196485B1 (pl) * 2000-05-11 2008-01-31 Inst Farmaceutyczny Stała doustna kompozycja farmaceutyczna zawierająca aminową pochodną kwasu bisfosfonowego i sposób jej wytwarzania
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
MXPA04009586A (es) 2002-05-10 2005-01-11 Hoffmann La Roche Acidos bisfosfonicos para el tratamiento y prevencion de la osteoporosis.
SI1596870T2 (sl) † 2002-12-20 2011-07-29 Hoffmann La Roche Formulacija z visokim odmerkom ibandronata
MXPA06000363A (es) * 2003-07-11 2006-03-28 Hoffmann La Roche Forma de dosificacion oral de mesilato de saquinavir.
EP1978933A2 (en) * 2005-12-15 2008-10-15 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
CN101489563A (zh) * 2006-07-06 2009-07-22 拜耳先灵医药股份有限公司 用于避孕和预防先天性畸形风险的药物制剂
GB0616794D0 (en) 2006-08-24 2006-10-04 Arrow Int Ltd Solid dosage form
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
KR102622198B1 (ko) * 2018-03-30 2024-01-09 한미약품 주식회사 빌다글립틴을 함유하는 경구용 고형제제 및 그의 제조 방법
CN112972400A (zh) * 2021-03-09 2021-06-18 华侨大学 可快速崩解的米诺膦酸颗粒及制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2405254C2 (de) * 1974-02-04 1982-05-27 Henkel KGaA, 4000 Düsseldorf Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper
US4711886A (en) * 1984-07-02 1987-12-08 Merck & Co., Inc. β-lactam derivatives as anti-inflammatory and antidegenerative agents
US4639338A (en) * 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
HU199151B (en) * 1987-03-10 1990-01-29 Yamanouchi Pharma Co Ltd Process for producing bis-phosphonic acid derivatives
FR2629716B1 (fr) * 1988-04-07 1991-07-19 Sanofi Sa Composition pharmaceutique pour administration orale a base d'un derive d'acide diphosphonique
PH27186A (en) * 1989-09-07 1993-04-16 Ciba Geigy Ag Double-coated granules of disodium pamidronate
FI89366C (fi) * 1990-12-20 1993-09-27 Leiras Oy Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat
TW237386B (bg) * 1992-04-15 1995-01-01 Ciba Geigy
SE501389C2 (sv) * 1992-04-24 1995-01-30 Leiras Oy Farmaceutiskt preparat och förfarande för dess framställning
US5358941A (en) * 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
FR2703590B1 (fr) * 1993-04-05 1995-06-30 Sanofi Elf Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .

Also Published As

Publication number Publication date
HRP950261B1 (en) 2003-08-31
IL113465A0 (en) 1995-07-31
MX9605222A (es) 1997-09-30
ES2183873T3 (es) 2003-04-01
CA2188567C (en) 2007-02-20
FI964315A (fi) 1996-10-25
BG62878B1 (bg) 2000-10-31
NO964567D0 (no) 1996-10-28
CA2188567A1 (en) 1995-11-09
SK283785B6 (sk) 2004-01-08
EP0756484A1 (en) 1997-02-05
FI964315A0 (fi) 1996-10-25
LV13114B (en) 2004-06-20
DE69528525T2 (de) 2003-11-27
ATE225661T1 (de) 2002-10-15
CN1147202A (zh) 1997-04-09
FI118206B (fi) 2007-08-31
IL113465A (en) 2005-09-25
HK1009246A1 (en) 1999-05-28
CZ315296A3 (en) 1997-04-16
UA44733C2 (uk) 2002-03-15
NZ284719A (en) 1998-06-26
CZ291574B6 (cs) 2003-04-16
PT756484E (pt) 2002-12-31
TW390813B (en) 2000-05-21
KR970702050A (ko) 1997-05-13
BG100911A (bg) 1997-07-31
EP0756484B1 (en) 2002-10-09
WO1995029679A1 (en) 1995-11-09
MY120491A (en) 2005-11-30
KR100390719B1 (ko) 2003-10-17
JPH09512551A (ja) 1997-12-16
YU49458B (sh) 2006-03-03
AU2393995A (en) 1995-11-29
SA95160013B1 (ar) 2005-11-23
CN1781489A (zh) 2006-06-07
HRP950261A2 (en) 1997-02-28
AU694217C (en) 2005-12-15
PL316987A1 (en) 1997-03-03
ZA953437B (en) 1996-01-17
RU2149003C1 (ru) 2000-05-20
HUT76297A (en) 1997-07-28
HU9602986D0 (en) 1997-01-28
DE69528525D1 (de) 2002-11-14
YU27395A (sh) 1998-07-10
CO4560546A1 (es) 1998-02-10
JP3838658B2 (ja) 2006-10-25
AU694217B2 (en) 1998-07-16
SK139096A3 (en) 1997-05-07
NO964567L (no) 1996-10-28

Similar Documents

Publication Publication Date Title
DK0756484T3 (da) Vådgranuleringsformulering til diphosphonsyrer
CA2149052A1 (en) Dry mix formulation for bisphosphonic acids
HK1072539A1 (en) Use of bisphosphonates in the preparation of a medicament for the treatment of conditings of abnormally increased bone turnover
HUP0204114A2 (hu) Bifoszfonáttartalmú parenterális gyógyászati készítmény
NZ332314A (en) Oral pharmaceutical preparation containing ibandronate or salts thereof in the form of an inner section containing the active ingredient surrounded by a coating free of the active ingredient
EP1178810B8 (en) Use of bisphosphonic acids for treating angiogenesis
CA2024694A1 (en) Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
WO2004058235A3 (en) Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin d derivative
CA2035179A1 (en) Pharmaceutical compositions containing insoluble salts of bisphosphonic acids
EP0341961A3 (en) Polymalonic acids as boneaffinity agents
ATE330616T1 (de) Verabreichung von bisphosphonaten durch inhalation zur behandlung von knochenresorption und osteoporosis
IS4392A (is) Pýridýlbisfosfónöt til notkunar sem efni til lækninga
BR9808233A (pt) Preparação farmacêutica
ES2152865A1 (es) Utilizacion de bisfosfonatos en la preparacion de composiciones farmaceuticas para uso intramuscular.
NO20006572D0 (no) Medikamenter inneholdende bisfosfonsyrer og deres derivater for forhindring og behandling av autoimmune sykdommer og allergier