DK0722736T3 - Topisk sammensætning indeholdende en antagonist for substans P - Google Patents
Topisk sammensætning indeholdende en antagonist for substans PInfo
- Publication number
- DK0722736T3 DK0722736T3 DK95402502T DK95402502T DK0722736T3 DK 0722736 T3 DK0722736 T3 DK 0722736T3 DK 95402502 T DK95402502 T DK 95402502T DK 95402502 T DK95402502 T DK 95402502T DK 0722736 T3 DK0722736 T3 DK 0722736T3
- Authority
- DK
- Denmark
- Prior art keywords
- antagonist
- substance
- composition containing
- topical composition
- topical
- Prior art date
Links
- QDZOEBFLNHCSSF-PFFBOGFISA-N (2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide Chemical compound C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](N)CCCNC(N)=N)C1=CC=CC=C1 QDZOEBFLNHCSSF-PFFBOGFISA-N 0.000 title 1
- 102100024304 Protachykinin-1 Human genes 0.000 title 1
- 101800003906 Substance P Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/046—Tachykinins, e.g. eledoisins, substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9415253A FR2728166A1 (fr) | 1994-12-19 | 1994-12-19 | Composition topique contenant un antagoniste de substance p |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0722736T3 true DK0722736T3 (da) | 2001-04-02 |
Family
ID=9469931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95402502T DK0722736T3 (da) | 1994-12-19 | 1995-11-09 | Topisk sammensætning indeholdende en antagonist for substans P |
Country Status (17)
Country | Link |
---|---|
US (2) | US5824650A (ja) |
EP (1) | EP0722736B1 (ja) |
JP (1) | JPH08208505A (ja) |
AR (1) | AR002007A1 (ja) |
AT (1) | ATE198986T1 (ja) |
BR (1) | BR9505408A (ja) |
CA (1) | CA2165521C (ja) |
DE (1) | DE69520032T2 (ja) |
DK (1) | DK0722736T3 (ja) |
ES (1) | ES2157307T3 (ja) |
FR (1) | FR2728166A1 (ja) |
GR (1) | GR3035652T3 (ja) |
HU (1) | HU218936B (ja) |
MX (1) | MX9505182A (ja) |
PL (1) | PL311918A1 (ja) |
PT (1) | PT722736E (ja) |
RU (1) | RU2124353C1 (ja) |
Families Citing this family (66)
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FR2732221B1 (fr) * | 1995-03-28 | 1997-04-25 | Oreal | Utilisation d'un antagoniste de cgrp pour traiter les rougeurs cutanees d'origine neurogene et composition obtenue |
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FR2677361A1 (fr) | 1991-06-04 | 1992-12-11 | Adir | Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2676442B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
FR2676447B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives du thiopyranopyrrole et leur preparation. |
FR2676446B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
FR2676443B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole et leur preparation. |
DE69232334T2 (de) | 1991-05-22 | 2002-11-14 | Pfizer Inc., New York | Substituierte 3-aminochinuclidine |
GB9113219D0 (en) | 1991-06-19 | 1991-08-07 | Fujisawa Pharmaceutical Co | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
UA39168C2 (uk) | 1991-06-20 | 2001-06-15 | Пфайзер, Інк. | Фторалкоксифенільні похідні піперидину або хінуклідину, що є антагоністами речовини p і фармацевтична композиція на їх основі |
TW202432B (ja) | 1991-06-21 | 1993-03-21 | Pfizer | |
US5288730A (en) | 1991-06-24 | 1994-02-22 | Merck Sharp & Dohme Limited | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
US5472978A (en) | 1991-07-05 | 1995-12-05 | Merck Sharp & Dohme Ltd. | Aromatic compounds, pharmaceutical compositions containing them and their use in therapy |
DE69208088T2 (de) | 1991-07-05 | 1996-11-14 | Merck Sharp & Dohme | Aromatische verbindungen, diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische anwendung |
JPH06509090A (ja) | 1991-07-10 | 1994-10-13 | メルク シヤープ エンド ドーム リミテツド | 芳香族化合物、それらを含む組成物、及び治療におけるそれらの使用 |
US5495047A (en) | 1991-07-10 | 1996-02-27 | Merck, Sharp & Dohme (Ltd.) | Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy |
MY110227A (en) | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
US5459270A (en) | 1991-08-20 | 1995-10-17 | Merck Sharp & Dohme Limited | Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them |
BR9206500A (pt) | 1991-09-26 | 1995-10-03 | Pfizer | Heterociclos contendo, nitrogênio tricíclico condensado como antagonistas de substancia receptora P |
WO1993009116A1 (en) | 1991-11-07 | 1993-05-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Quinuclidine compound and medicinal use thereof |
ATE161821T1 (de) | 1991-11-12 | 1998-01-15 | Pfizer | Azyklische ethylendiaminderivate als 'substance p rezeptor' antagonisten |
CA2083891A1 (en) | 1991-12-03 | 1993-06-04 | Angus Murray Macleod | Heterocyclic compounds, compositions containing them and their use in therapy |
US5569662A (en) * | 1992-03-23 | 1996-10-29 | Pfizer Inc. | Quinuclidine derivatives as substance P antagonists |
DE9211006U1 (de) * | 1992-08-17 | 1993-12-16 | Kao Corporation GmbH, 40472 Düsseldorf | Mittel zur Haarbehandlung |
JP2656699B2 (ja) | 1992-10-21 | 1997-09-24 | ファイザー製薬株式会社 | 置換ベンジルアミノキヌクリジン |
US5716625A (en) * | 1994-12-21 | 1998-02-10 | Cosmederm Technologies | Formulations and methods for reducing skin irritation |
-
1994
- 1994-12-19 FR FR9415253A patent/FR2728166A1/fr active Granted
-
1995
- 1995-11-09 PT PT95402502T patent/PT722736E/pt unknown
- 1995-11-09 AT AT95402502T patent/ATE198986T1/de not_active IP Right Cessation
- 1995-11-09 EP EP95402502A patent/EP0722736B1/fr not_active Revoked
- 1995-11-09 DE DE69520032T patent/DE69520032T2/de not_active Revoked
- 1995-11-09 ES ES95402502T patent/ES2157307T3/es not_active Expired - Lifetime
- 1995-11-09 DK DK95402502T patent/DK0722736T3/da active
- 1995-12-11 MX MX9505182A patent/MX9505182A/es unknown
- 1995-12-13 BR BR9505408A patent/BR9505408A/pt active Search and Examination
- 1995-12-15 AR ARP950100577A patent/AR002007A1/es unknown
- 1995-12-18 JP JP7329297A patent/JPH08208505A/ja active Pending
- 1995-12-18 CA CA002165521A patent/CA2165521C/fr not_active Expired - Fee Related
- 1995-12-18 HU HU9503623A patent/HU218936B/hu not_active IP Right Cessation
- 1995-12-18 RU RU95121151A patent/RU2124353C1/ru active
- 1995-12-18 PL PL95311918A patent/PL311918A1/xx unknown
- 1995-12-19 US US08/575,682 patent/US5824650A/en not_active Expired - Lifetime
-
1998
- 1998-06-15 US US09/094,558 patent/US5972892A/en not_active Expired - Lifetime
-
2001
- 2001-03-29 GR GR20010400502T patent/GR3035652T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU218936B (hu) | 2001-01-29 |
HU9503623D0 (en) | 1996-02-28 |
EP0722736B1 (fr) | 2001-01-31 |
ES2157307T3 (es) | 2001-08-16 |
PT722736E (pt) | 2001-05-31 |
GR3035652T3 (en) | 2001-06-29 |
JPH08208505A (ja) | 1996-08-13 |
CA2165521C (fr) | 2002-07-16 |
EP0722736A1 (fr) | 1996-07-24 |
MX9505182A (es) | 1997-02-28 |
US5972892A (en) | 1999-10-26 |
HUT74830A (en) | 1997-02-28 |
CA2165521A1 (fr) | 1996-06-20 |
US5824650A (en) | 1998-10-20 |
PL311918A1 (en) | 1996-06-24 |
FR2728166B1 (ja) | 1997-02-07 |
AR002007A1 (es) | 1998-01-07 |
BR9505408A (pt) | 1997-10-28 |
DE69520032T2 (de) | 2001-05-23 |
FR2728166A1 (fr) | 1996-06-21 |
RU2124353C1 (ru) | 1999-01-10 |
DE69520032D1 (de) | 2001-03-08 |
ATE198986T1 (de) | 2001-02-15 |
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