DK0667910T3 - En Bacillus-promoter, afledt fra en variant af en alpha-amylase-promoter fra Bacillus licheniformis - Google Patents
En Bacillus-promoter, afledt fra en variant af en alpha-amylase-promoter fra Bacillus licheniformisInfo
- Publication number
- DK0667910T3 DK0667910T3 DK92923722T DK92923722T DK0667910T3 DK 0667910 T3 DK0667910 T3 DK 0667910T3 DK 92923722 T DK92923722 T DK 92923722T DK 92923722 T DK92923722 T DK 92923722T DK 0667910 T3 DK0667910 T3 DK 0667910T3
- Authority
- DK
- Denmark
- Prior art keywords
- promoter
- bacillus
- variant
- alpha
- derived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
- C12N9/1074—Cyclomaltodextrin glucanotransferase (2.4.1.19)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK9100343 | 1991-11-14 | ||
| PCT/DK1992/000338 WO1993010249A1 (en) | 1991-11-14 | 1992-11-13 | A bacillus promoter derived from a variant of a bacillus licheniformis x-amylase promoter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0667910T3 true DK0667910T3 (da) | 2003-12-01 |
Family
ID=8153698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92923722T DK0667910T3 (da) | 1991-11-14 | 1992-11-13 | En Bacillus-promoter, afledt fra en variant af en alpha-amylase-promoter fra Bacillus licheniformis |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5698415A (da) |
| EP (1) | EP0667910B1 (da) |
| JP (1) | JP3529774B2 (da) |
| AT (1) | ATE248223T1 (da) |
| AU (1) | AU661070B2 (da) |
| CA (1) | CA2123496C (da) |
| DE (1) | DE69233178T2 (da) |
| DK (1) | DK0667910T3 (da) |
| FI (1) | FI112668B (da) |
| IL (1) | IL103750A0 (da) |
| WO (1) | WO1993010249A1 (da) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5955310A (en) * | 1998-02-26 | 1999-09-21 | Novo Nordisk Biotech, Inc. | Methods for producing a polypeptide in a bacillus cell |
| US6300115B1 (en) | 1998-05-18 | 2001-10-09 | Enzyme Bio-Systems Ltd. | Pullulanase expression constructs containing α-amylase promoter and leader sequences |
| EP1995319B1 (en) | 2002-04-10 | 2011-08-31 | Novozymes A/S | Bacillus licheniformis mutant host cell |
| WO2003087149A2 (en) | 2002-04-10 | 2003-10-23 | Novozymes A/S | Bacillus licheniformis mutant host cell |
| WO2004101763A2 (en) | 2003-05-12 | 2004-11-25 | Genencor International, Inc. | Novel lipolytic enzyme lip1 |
| US20070213518A1 (en) | 2003-05-12 | 2007-09-13 | Jones Brian E | Novel Lipolytic Enzyme Lip2 |
| EP1639107B1 (en) | 2003-06-19 | 2013-08-14 | Novozymes A/S | Improved proteases and methods for producing them |
| CN101426925A (zh) * | 2004-03-31 | 2009-05-06 | 诺维信生物聚合物公司 | 在芽孢杆菌细胞中生产透明质酸的方法 |
| US20080044853A1 (en) | 2004-06-21 | 2008-02-21 | Novozymes A/S | Stably Maintained Multiple Copies of at Least Two Orf in the Same Orientation |
| CN101611145B (zh) | 2006-12-21 | 2013-08-14 | 诺维信股份有限公司 | 用于在细菌细胞中表达基因的修饰型信使rna稳定化序列 |
| MX2009009967A (es) | 2007-03-23 | 2009-10-07 | Danisco Us Inc Genencor Div | Produccion mejorada de amilasa por adicion n-terminal a proteina amilasa madura. |
| US7618801B2 (en) | 2007-10-30 | 2009-11-17 | Danison US Inc. | Streptomyces protease |
| DK2257629T3 (da) | 2008-03-28 | 2016-06-13 | Danisco Us Inc | Fremgangsmåde til locusamplifikation i en bakteriecelle |
| US20110306106A1 (en) | 2009-01-16 | 2011-12-15 | Otsuka Chemical Co., Ltd | High expression promoter and method for producing gene product using same |
| WO2010097436A1 (en) | 2009-02-27 | 2010-09-02 | Novozymes A/S | Mutant cells having reduced expression of metallopeptidase, suitable for recombinant polypeptide production |
| AR076941A1 (es) | 2009-06-11 | 2011-07-20 | Danisco Us Inc | Cepa de bacillus para una mayor produccion de proteina |
| WO2011000924A1 (en) | 2009-07-03 | 2011-01-06 | Abbott Products Gmbh | Spray-dried amylase, pharmaceutical preparations comprising the same and use |
| WO2011084695A1 (en) | 2009-12-21 | 2011-07-14 | Novozymes, Inc. | Methods for producing heterologous polypeptides in thiol-disulfide oxidoreductase-deficient bacterial mutant cells |
| CN103443278B (zh) | 2011-03-23 | 2017-07-04 | 诺维信公司 | 生产分泌型多肽的方法 |
| CN106754833B (zh) * | 2017-01-16 | 2020-06-09 | 广东溢多利生物科技股份有限公司 | 在枯草芽孢杆菌中高效表达普鲁兰酶的方法及重组枯草芽孢杆菌 |
| US20200318086A1 (en) | 2017-11-10 | 2020-10-08 | Novozymes A/S | Temperature-sensitive cas9 protein |
| US20210017544A1 (en) | 2017-12-22 | 2021-01-21 | Novozymes A/S | Counter-Selection by Inhibition of Conditionally Essential Genes |
| MX2021010109A (es) | 2019-02-20 | 2021-09-21 | Basf Se | Proceso de fermentacion industrial para bacillus mediante el uso de un medio definido y una alimentacion de oligoelementos. |
| US20220186177A1 (en) | 2019-02-20 | 2022-06-16 | Basf Se | Industrial fermentation process for bacillus using defined medium and magnesium feed |
| CN113939588A (zh) | 2019-05-15 | 2022-01-14 | 诺维信公司 | 温度敏感性的rna指导的内切核酸酶 |
| EP3990629A1 (en) | 2019-06-25 | 2022-05-04 | Novozymes A/S | Counter-selection by inhibition of conditionally essential genes |
| MX2023001016A (es) | 2020-07-24 | 2023-03-01 | Basf Se | Eliminacion simple de alanina racemasa y transcomplementacion. |
| BR112023001384A2 (pt) | 2020-07-28 | 2023-02-14 | Basf Se | Método para cultivar uma célula hospedeira de bacillus, e, cultura de célula hospedeira de bacillus |
| CN116323960A (zh) | 2020-07-28 | 2023-06-23 | 巴斯夫欧洲公司 | 使用部分收获的芽孢杆菌工业发酵工艺 |
| MX2023001273A (es) | 2020-07-28 | 2023-03-03 | Basf Se | Proceso de fermentacion industrial para bacillus mediante el uso de cambio de velocidad de alimentacion. |
| BR112023005111A2 (pt) | 2020-09-22 | 2023-04-18 | Basf Se | Método para recuperar uma proteína de interesse de um caldo de fermentação bacteriana, e, uso de pelo menos um floculante |
| EP4225779A2 (en) | 2020-10-07 | 2023-08-16 | Basf Se | Bacillus cell with reduced lipase and/or esterase side activities |
| WO2022129166A1 (en) | 2020-12-15 | 2022-06-23 | Novozymes A/S | Mutated host cells with reduced cell motility |
| EP4359424A1 (en) | 2021-06-24 | 2024-05-01 | Basf Se | Improved bacillus production host |
| BR112023027016A2 (pt) | 2021-06-24 | 2024-03-12 | Basf Se | Célula hospedeira modificada de bacillus compreendendo uma proteína reguladora da matriz extracelular a alterada e/ou uma proteína reguladora da matriz extracelular b alterada, método para produzir um composto de interesse, e, proteínas reguladoras das matrizes extracelulares a e b alteradas |
| BR112023027009A2 (pt) | 2021-06-24 | 2024-03-12 | Basf Se | Célula hospedeira modificada de bacillus licheniformis, e, métodos para produzir um composto de interesse e para aumentar a pureza de um composto de interesse |
| WO2023117970A1 (en) | 2021-12-20 | 2023-06-29 | Basf Se | Method for improved production of intracellular proteins in bacillus |
| WO2024028338A1 (en) | 2022-08-02 | 2024-02-08 | Basf Se | Stabilized protein production process using bacillus host cells |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4769327A (en) * | 1985-03-29 | 1988-09-06 | Biotechnica International, Inc. | Secretion vector |
-
1992
- 1992-11-13 DK DK92923722T patent/DK0667910T3/da active
- 1992-11-13 EP EP92923722A patent/EP0667910B1/en not_active Expired - Lifetime
- 1992-11-13 JP JP50889993A patent/JP3529774B2/ja not_active Expired - Lifetime
- 1992-11-13 DE DE69233178T patent/DE69233178T2/de not_active Expired - Lifetime
- 1992-11-13 AU AU29430/92A patent/AU661070B2/en not_active Ceased
- 1992-11-13 CA CA002123496A patent/CA2123496C/en not_active Expired - Lifetime
- 1992-11-13 WO PCT/DK1992/000338 patent/WO1993010249A1/en active IP Right Grant
- 1992-11-13 AT AT92923722T patent/ATE248223T1/de not_active IP Right Cessation
- 1992-11-13 IL IL103750A patent/IL103750A0/xx unknown
- 1992-11-13 US US08/240,748 patent/US5698415A/en not_active Expired - Lifetime
-
1994
- 1994-05-13 FI FI942228A patent/FI112668B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0667910B1 (en) | 2003-08-27 |
| DE69233178D1 (de) | 2003-10-02 |
| FI942228A0 (fi) | 1994-05-13 |
| CA2123496C (en) | 2004-02-03 |
| ATE248223T1 (de) | 2003-09-15 |
| WO1993010249A1 (en) | 1993-05-27 |
| US5698415A (en) | 1997-12-16 |
| FI112668B (fi) | 2003-12-31 |
| FI942228A (fi) | 1994-07-13 |
| DE69233178T2 (de) | 2004-06-17 |
| EP0667910A1 (en) | 1995-08-23 |
| JP3529774B2 (ja) | 2004-05-24 |
| IL103750A0 (en) | 1993-04-04 |
| CA2123496A1 (en) | 1993-05-27 |
| AU2943092A (en) | 1993-06-15 |
| JPH07504085A (ja) | 1995-05-11 |
| AU661070B2 (en) | 1995-07-13 |
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