DK0654086T3 - Vacciner mod Aujeszky's sygdom og andre dyresygdomme indeholdende mutanter af pseudo-rabies-virus - Google Patents

Vacciner mod Aujeszky's sygdom og andre dyresygdomme indeholdende mutanter af pseudo-rabies-virus

Info

Publication number
DK0654086T3
DK0654086T3 DK93916297T DK93916297T DK0654086T3 DK 0654086 T3 DK0654086 T3 DK 0654086T3 DK 93916297 T DK93916297 T DK 93916297T DK 93916297 T DK93916297 T DK 93916297T DK 0654086 T3 DK0654086 T3 DK 0654086T3
Authority
DK
Denmark
Prior art keywords
disease
animal diseases
pct
pseudo
vaccines
Prior art date
Application number
DK93916297T
Other languages
Danish (da)
English (en)
Inventor
Robertus Jacobus Mari Moormann
Bernardus Petrus Huber Peeters
Jan Maria Antonius Pol
Arnold Leonard Josef Gielkens
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK0654086T3 publication Critical patent/DK0654086T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16761—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK93916297T 1992-07-09 1993-07-08 Vacciner mod Aujeszky's sygdom og andre dyresygdomme indeholdende mutanter af pseudo-rabies-virus DK0654086T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92202096 1992-07-09
PCT/NL1993/000146 WO1994001573A1 (en) 1992-07-09 1993-07-08 Vaccines against aujeszky's disease and other animal diseases containing pseudorabies virus mutants

Publications (1)

Publication Number Publication Date
DK0654086T3 true DK0654086T3 (da) 2000-06-13

Family

ID=8210764

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93916297T DK0654086T3 (da) 1992-07-09 1993-07-08 Vacciner mod Aujeszky's sygdom og andre dyresygdomme indeholdende mutanter af pseudo-rabies-virus

Country Status (18)

Country Link
US (1) US5674500A (enExample)
EP (1) EP0654086B1 (enExample)
JP (1) JPH07509127A (enExample)
KR (1) KR100341994B1 (enExample)
CN (1) CN1124159C (enExample)
AT (1) ATE189000T1 (enExample)
AU (1) AU684252B2 (enExample)
CA (1) CA2139507C (enExample)
DE (1) DE69327656T2 (enExample)
DK (1) DK0654086T3 (enExample)
ES (1) ES2143507T3 (enExample)
HU (1) HU220099B (enExample)
NZ (1) NZ254267A (enExample)
PL (1) PL174219B1 (enExample)
RU (1) RU2158308C2 (enExample)
TW (1) TW289731B (enExample)
WO (1) WO1994001573A1 (enExample)
ZA (1) ZA934882B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9202724A (es) * 1991-06-06 1992-12-31 Stichting Centr Diergeneeskund Composicion que comprende un vector recombinante del agente lelystad y vacuna que comprende la misma.
US6007825A (en) * 1991-12-23 1999-12-28 American Cyanamid Company Serpulina hyodysenteriae vaccine comprising a tly gene mutant
US7223411B1 (en) 1992-07-31 2007-05-29 Dana-Farber Cancer Institute Herpesvirus replication defective mutants
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
AU696336B2 (en) * 1993-03-19 1998-09-10 Cantab Pharmaceuticals Research Limited Defective mutant non-retroviral virus (e.g. HSV) as vaccine
EP0659885A1 (en) * 1993-12-21 1995-06-28 Akzo Nobel N.V. Vaccine against viruses associated with antibody-dependent-enhancement of viral infectivity
EP0693551A1 (en) * 1994-07-18 1996-01-24 Akzo Nobel N.V. gD-negative bovine herpesvirus mutant, capable of direct cell-to-cell transmission
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US6399354B1 (en) 1998-07-31 2002-06-04 President And Fellows Of Harvard College Replication-competent virus expressing a detectable fusion protein
JP3961222B2 (ja) * 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Ｐｒｒｓｖワクチン
CA2370372C (en) * 1999-04-22 2009-02-24 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
WO2004053103A2 (en) * 2002-12-11 2004-06-24 University Of Massachusetts METHOD OF INTRODUCING siRNA INTO ADIPOCYTES
TW200604526A (en) * 2004-06-18 2006-02-01 Unviersity Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) * 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
ES2603553T3 (es) 2005-06-24 2017-02-28 Regents Of The University Of Minnesota Virus PRRS, clones infecciosos, mutantes de los mismos, y métodos de uso
CN101081298A (zh) * 2007-06-26 2007-12-05 陈少莺 一种猪伪狂犬病新型亚单位疫苗制备方法
KR101653177B1 (ko) * 2008-08-25 2016-09-01 베링거잉겔하임베트메디카인코퍼레이티드 고병원성 돼지 생식기 및 호흡기 증후군(ｈｐ ｐｒｒｓ)에 대한 백신
CN101457215B (zh) * 2008-12-01 2010-11-17 华中农业大学 重组猪伪狂犬病毒-猪繁殖与呼吸综合征病毒-猪圆环病毒基因工程毒株及应用
AR078253A1 (es) * 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
RU2439150C1 (ru) * 2010-11-16 2012-01-10 Государственное научное учреждение Всероссийский научно-исследовательский институт ветеринарной вирусологии и микробиологии Штамм "ас-21/07" вируса ауески для изготовления вакцинных и диагностических препаратов
EP2675476B1 (en) 2011-02-17 2015-09-16 Boehringer Ingelheim Vetmedica GmbH Commercial scale process for production of prrsv
UA117272C2 (uk) 2011-02-17 2018-07-10 Бьорінгер Інгельхайм Ветмедіка Гмбх Новий європейський штам prrsv
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
CN104250640A (zh) * 2014-08-22 2014-12-31 普莱柯生物工程股份有限公司 猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用
CN111560355A (zh) * 2015-03-20 2020-08-21 普莱柯生物工程股份有限公司 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859587A (en) * 1984-06-04 1989-08-22 Institut Merieux Recombinant herpes simplex viruses, vaccines and methods
AU591145B2 (en) * 1985-07-29 1989-11-30 Pharmacia & Upjohn Company Virus vaccine with deletion of an antigen of the wild-type virus
US5352575A (en) * 1985-10-04 1994-10-04 The Upjohn Company Pseudorabies virus protein
US4999296A (en) * 1986-04-29 1991-03-12 Novagene, Inc. Thymidine kinase negative insertion mutants of pseudorabies virus and methods for the production of same
NL8902087A (nl) * 1989-08-17 1991-03-18 Stichting Tech Wetenschapp Niet-natuurlijk voorkomend pseudorabiesvirus en vaccins die dit bevatten.
EP0953648A3 (en) * 1990-09-25 2007-09-12 Cantab Pharmaceuticals Research Limited Viral defective vaccine produced by transcomplementing cell line
EP0606437B1 (en) * 1992-07-30 2005-02-02 Akzo Nobel N.V. Non-shedding live herpesvirus vaccine

Also Published As

Publication number Publication date
ES2143507T3 (es) 2000-05-16
PL307049A1 (en) 1995-05-02
PL174219B1 (pl) 1998-06-30
EP0654086B1 (en) 2000-01-19
JPH07509127A (ja) 1995-10-12
CA2139507A1 (en) 1994-01-20
RU95105518A (ru) 1997-03-27
DE69327656D1 (de) 2000-02-24
EP0654086A1 (en) 1995-05-24
US5674500A (en) 1997-10-07
ZA934882B (en) 1994-02-03
HU220099B (hu) 2001-10-28
ATE189000T1 (de) 2000-02-15
RU2158308C2 (ru) 2000-10-27
CA2139507C (en) 2005-04-19
DE69327656T2 (de) 2000-08-03
AU4589893A (en) 1994-01-31
AU684252B2 (en) 1997-12-11
WO1994001573A1 (en) 1994-01-20
HUT70986A (en) 1995-11-28
TW289731B (enExample) 1996-11-01
HU9500039D0 (en) 1995-03-28
KR100341994B1 (ko) 2002-11-30
CN1124159C (zh) 2003-10-15
CN1086143A (zh) 1994-05-04
NZ254267A (en) 1996-08-27

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