DE69327656D1 - Impfstoffe gegen die aujeskyskrankheit und sonstige tierkrankheiten, die pseudorabies virusmutanten enthalten - Google Patents

Impfstoffe gegen die aujeskyskrankheit und sonstige tierkrankheiten, die pseudorabies virusmutanten enthalten

Info

Publication number
DE69327656D1
DE69327656D1 DE69327656T DE69327656T DE69327656D1 DE 69327656 D1 DE69327656 D1 DE 69327656D1 DE 69327656 T DE69327656 T DE 69327656T DE 69327656 T DE69327656 T DE 69327656T DE 69327656 D1 DE69327656 D1 DE 69327656D1
Authority
DE
Germany
Prior art keywords
disease
pseudorabies virus
animal diseases
pct
aujesky
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69327656T
Other languages
English (en)
Other versions
DE69327656T2 (de
Inventor
Petrus Peeters
Maria Pol
Leonard Gielkens
Jacobus Moormann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of DE69327656D1 publication Critical patent/DE69327656D1/de
Publication of DE69327656T2 publication Critical patent/DE69327656T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16761—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE1993627656 1992-07-09 1993-07-08 Impfstoffe gegen die aujeskyskrankheit und sonstige tierkrankheiten, die pseudorabies virusmutanten enthalten Expired - Fee Related DE69327656T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92202096 1992-07-09
PCT/NL1993/000146 WO1994001573A1 (en) 1992-07-09 1993-07-08 Vaccines against aujeszky's disease and other animal diseases containing pseudorabies virus mutants

Publications (2)

Publication Number Publication Date
DE69327656D1 true DE69327656D1 (de) 2000-02-24
DE69327656T2 DE69327656T2 (de) 2000-08-03

Family

ID=8210764

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1993627656 Expired - Fee Related DE69327656T2 (de) 1992-07-09 1993-07-08 Impfstoffe gegen die aujeskyskrankheit und sonstige tierkrankheiten, die pseudorabies virusmutanten enthalten

Country Status (18)

Country Link
US (1) US5674500A (de)
EP (1) EP0654086B1 (de)
JP (1) JPH07509127A (de)
KR (1) KR100341994B1 (de)
CN (1) CN1124159C (de)
AT (1) ATE189000T1 (de)
AU (1) AU684252B2 (de)
CA (1) CA2139507C (de)
DE (1) DE69327656T2 (de)
DK (1) DK0654086T3 (de)
ES (1) ES2143507T3 (de)
HU (1) HU220099B (de)
NZ (1) NZ254267A (de)
PL (1) PL174219B1 (de)
RU (1) RU2158308C2 (de)
TW (1) TW289731B (de)
WO (1) WO1994001573A1 (de)
ZA (1) ZA934882B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2290906C (en) * 1991-06-06 2003-04-01 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US6007825A (en) * 1991-12-23 1999-12-28 American Cyanamid Company Serpulina hyodysenteriae vaccine comprising a tly gene mutant
US7223411B1 (en) 1992-07-31 2007-05-29 Dana-Farber Cancer Institute Herpesvirus replication defective mutants
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
EP0689603A1 (de) * 1993-03-19 1996-01-03 Cantab Pharmaceuticals Research Limited Defektiver mutanter nicht-retroviraler virus (2.b.hsv) zum impstoff
EP0659885A1 (de) * 1993-12-21 1995-06-28 Akzo Nobel N.V. Impstoffe gegen von Antikörper abhängende Vergrösserung (ADE) der Virus-Infektivität
EP0693551A1 (de) 1994-07-18 1996-01-24 Akzo Nobel N.V. gD-Negative Rinder-Herpesvirus Mutanten, mit der Fähigkeit zur direkten Zell zu Zell Übertragung
EP0839912A1 (de) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US6399354B1 (en) 1998-07-31 2002-06-04 President And Fellows Of Harvard College Replication-competent virus expressing a detectable fusion protein
CA2366072C (en) * 1999-03-08 2007-07-10 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
CA2650236C (en) * 1999-04-22 2016-01-12 United States Of America, As Represented By The Secretary Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
US20050014264A1 (en) * 2002-12-11 2005-01-20 University Of Massachusetts Method of introducing siRNA into adipocytes
RU2007101725A (ru) * 2004-06-18 2008-07-27 Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) Идентификация инфицированных вирусом и вакцинированных вирусом организмов
US7632636B2 (en) * 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
SI1904631T1 (sl) 2005-06-24 2012-09-28 Univ Minnesota Virusi PRRS, infekciozni kloni, njihovi mutanti in postopki uporabe
CN101081298A (zh) * 2007-06-26 2007-12-05 陈少莺 一种猪伪狂犬病新型亚单位疫苗制备方法
WO2010025109A1 (en) * 2008-08-25 2010-03-04 Boehringer Ingelheim Vetmedia, Inc. Vaccine against highly pathogenic porcine reproductive and respiratory syndrome (hp prrs)
CN101457215B (zh) * 2008-12-01 2010-11-17 华中农业大学 重组猪伪狂犬病毒-猪繁殖与呼吸综合征病毒-猪圆环病毒基因工程毒株及应用
TWI627281B (zh) * 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
JP2014506795A (ja) 2011-02-17 2014-03-20 ベーリンガー インゲルハイム フェトメディカ ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｐｒｒｓｖの工業規模の製造方法
UA117272C2 (uk) 2011-02-17 2018-07-10 Бьорінгер Інгельхайм Ветмедіка Гмбх Новий європейський штам prrsv
WO2013017570A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh Novel prrs virus inducing type i interferon in susceptible cells
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2014150822A2 (en) 2013-03-15 2014-09-25 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
CN104250640A (zh) * 2014-08-22 2014-12-31 普莱柯生物工程股份有限公司 猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用
CN111560355A (zh) * 2015-03-20 2020-08-21 普莱柯生物工程股份有限公司 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2559384B2 (ja) * 1985-07-29 1996-12-04 ジ・アップジョン・カンパニ− ウイルスワクチン
US5352575A (en) * 1985-10-04 1994-10-04 The Upjohn Company Pseudorabies virus protein
US4999296A (en) * 1986-04-29 1991-03-12 Novagene, Inc. Thymidine kinase negative insertion mutants of pseudorabies virus and methods for the production of same
NL8902087A (nl) * 1989-08-17 1991-03-18 Stichting Tech Wetenschapp Niet-natuurlijk voorkomend pseudorabiesvirus en vaccins die dit bevatten.
WO1992005263A1 (en) * 1990-09-25 1992-04-02 Cantab Pharmaceuticals Research Limited Viral defective vaccine produced by transcomplementing cell line
ATE288483T1 (de) * 1992-07-30 2005-02-15 Akzo Nobel Nv Nicht-verbreitendes lebendes herpesvirusvakzin

Also Published As

Publication number Publication date
DE69327656T2 (de) 2000-08-03
CN1124159C (zh) 2003-10-15
WO1994001573A1 (en) 1994-01-20
ES2143507T3 (es) 2000-05-16
HU220099B (hu) 2001-10-28
HU9500039D0 (en) 1995-03-28
AU4589893A (en) 1994-01-31
EP0654086A1 (de) 1995-05-24
EP0654086B1 (de) 2000-01-19
AU684252B2 (en) 1997-12-11
ZA934882B (en) 1994-02-03
US5674500A (en) 1997-10-07
CN1086143A (zh) 1994-05-04
CA2139507A1 (en) 1994-01-20
DK0654086T3 (da) 2000-06-13
PL174219B1 (pl) 1998-06-30
ATE189000T1 (de) 2000-02-15
RU2158308C2 (ru) 2000-10-27
HUT70986A (en) 1995-11-28
NZ254267A (en) 1996-08-27
TW289731B (de) 1996-11-01
RU95105518A (ru) 1997-03-27
CA2139507C (en) 2005-04-19
KR100341994B1 (ko) 2002-11-30
JPH07509127A (ja) 1995-10-12
PL307049A1 (en) 1995-05-02

Similar Documents

Publication Publication Date Title
DE69327656D1 (de) Impfstoffe gegen die aujeskyskrankheit und sonstige tierkrankheiten, die pseudorabies virusmutanten enthalten
ATE231184T1 (de) Impfstoffe gegen die pest
DE69529748D1 (de) Polynukleotide vakzine gegen den papilloma virus
Rotman et al. IL‐12 eliminates the Th‐2 dependent protective immune response of mice to larval Strongyloides stercoralis
Gierynska et al. Induction of CD8 T-cell-specific systemic and mucosal immunity against herpes simplex virus with CpG-peptide complexes
Vanloubbeeck et al. The immunology of Leishmania infection and the implications for vaccine development
TR200001835T2 (tr) Aşı.
PH25776A (en) Pseudorabies virus mutants incapable of producing glycoprotein x
SE9003198D0 (sv) Fish vaccine comprising a virulent, invasive bacterium
Rosado-Vallado et al. Aluminium phosphate potentiates the efficacy of DNA vaccines against Leishmania mexicana
DE69333751D1 (de) Nicht-verbreitendes lebendes herpesvirusvakzin
Vanrompay et al. Protection of turkeys against Chlamydophila psittaci challenge by parenteral and mucosal inoculations and the effect of turkey interferon‐γ on genetic immunization
EP0596959A4 (de) System der bereitstellung eines impfstoffes auf peptidbasis, das sein eigenes adjuvans bildet, und seine herstellung.
DE10399019I2 (de) Gefl}gelkrankheit verursachende neue Bakterie und daraus stammender Impfstoff.
Rogers et al. The human cytokine response to Leishmania major early after exposure to the parasite in vitro
EP0612532A3 (de) Hunde Coronavirus Impfstoff aus einem Katzen-enterischen Coronavirus
EA200301125A1 (ru) Вакцины, включающие в качестве адъюванта интерферон типа i, и связанные с этим способы
Feng et al. P55, an immunogenic but nonprotective 55-kilodalton Borrelia burgdorferi protein in murine Lyme disease
Thompson et al. Optimal induction of upper respiratory tract immunity to reovirus 1/L by combined upper and lower respiratory tract inoculation
ES2105984A1 (es) Adenovirus recombinantes que expresan antigenos del virus de la gastroenteritis porcina transmisible (vgpt) y su empleo en la formacion de vacunas.
NZ330913A (en) Antigens for preventing and reducing parasite infection and disease
SE9401596D0 (sv) New compounds
Knopf et al. Interleukin-12 as an Adjuvant for an
UA52796C2 (uk) Вакцина абацилярна антракол проти сибірки тварин

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee