DE69333751D1 - Nicht-verbreitendes lebendes herpesvirusvakzin - Google Patents
Nicht-verbreitendes lebendes herpesvirusvakzinInfo
- Publication number
- DE69333751D1 DE69333751D1 DE69333751T DE69333751T DE69333751D1 DE 69333751 D1 DE69333751 D1 DE 69333751D1 DE 69333751 T DE69333751 T DE 69333751T DE 69333751 T DE69333751 T DE 69333751T DE 69333751 D1 DE69333751 D1 DE 69333751D1
- Authority
- DE
- Germany
- Prior art keywords
- vaccine
- pct
- pseudorabies virus
- mutant
- live
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000701093 Suid alphaherpesvirus 1 Species 0.000 abstract 3
- 229960005486 vaccine Drugs 0.000 abstract 3
- 101000686824 Enterobacteria phage N4 Virion DNA-directed RNA polymerase Proteins 0.000 abstract 2
- 101000644628 Escherichia phage Mu Tail fiber assembly protein U Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 229940124841 Herpesvirus vaccine Drugs 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000001902 propagating effect Effects 0.000 abstract 1
- 241001529453 unidentified herpesvirus Species 0.000 abstract 1
- 229940126580 vector vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A61K39/265—Infectious rhinotracheitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16721—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP92202370 | 1992-07-30 | ||
EP92202370 | 1992-07-30 | ||
PCT/EP1993/001661 WO1994003595A1 (en) | 1992-07-30 | 1993-06-28 | Non-shedding live herpesvirus vaccine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69333751D1 true DE69333751D1 (de) | 2005-03-10 |
DE69333751T2 DE69333751T2 (de) | 2005-12-29 |
Family
ID=8210818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1993633751 Expired - Fee Related DE69333751T2 (de) | 1992-07-30 | 1993-06-28 | Nicht-verbreitendes lebendes herpesvirusvakzin |
Country Status (7)
Country | Link |
---|---|
US (1) | US5626850A (de) |
EP (1) | EP0606437B1 (de) |
JP (1) | JPH07500972A (de) |
AT (1) | ATE288483T1 (de) |
AU (1) | AU4560693A (de) |
DE (1) | DE69333751T2 (de) |
WO (1) | WO1994003595A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69229390T2 (de) | 1991-08-26 | 1999-11-11 | Immuno Ag, Wien | Direkt molekuläre Klonierung eines modifizierten Genoms eines Chordopocken-Virus |
TW289731B (de) * | 1992-07-09 | 1996-11-01 | Akzo Nv | |
US7223411B1 (en) | 1992-07-31 | 2007-05-29 | Dana-Farber Cancer Institute | Herpesvirus replication defective mutants |
US5612215A (en) * | 1992-12-07 | 1997-03-18 | Ribozyme Pharmaceuticals, Inc. | Stromelysin targeted ribozymes |
EP0689603A1 (de) * | 1993-03-19 | 1996-01-03 | Cantab Pharmaceuticals Research Limited | Defektiver mutanter nicht-retroviraler virus (2.b.hsv) zum impstoff |
EP0659885A1 (de) * | 1993-12-21 | 1995-06-28 | Akzo Nobel N.V. | Impstoffe gegen von Antikörper abhängende Vergrösserung (ADE) der Virus-Infektivität |
DK0758397T3 (da) * | 1994-04-29 | 2005-10-10 | Baxter Healthcare Sa | Rekombinante poxvira med fremmede polynucleotider i essentielle regioner |
EP0693551A1 (de) | 1994-07-18 | 1996-01-24 | Akzo Nobel N.V. | gD-Negative Rinder-Herpesvirus Mutanten, mit der Fähigkeit zur direkten Zell zu Zell Übertragung |
GB9415369D0 (en) * | 1994-07-29 | 1994-09-21 | Lynxvale Ltd | Mutant virus |
ATE324435T1 (de) * | 1995-02-21 | 2006-05-15 | Cantab Pharmaceuticals Res Ltd | Virale zubereitungen, vektoren, immunogene und impfstoffe |
DE19626614A1 (de) * | 1996-07-02 | 1998-01-08 | Immuno Ag | Komplex aus Antigen und Zellbestandteil, Impfstoffzusammensetzung, welche den Komplex enthält, pharmazeutische Präparation sowie Verfahren zur Herstellung des Komplexes |
US6399354B1 (en) | 1998-07-31 | 2002-06-04 | President And Fellows Of Harvard College | Replication-competent virus expressing a detectable fusion protein |
WO2001023649A1 (en) | 1999-09-29 | 2001-04-05 | Shin-Etsu Handotai Co., Ltd. | Wafer, epitaxial filter, and method of manufacture thereof |
CN103468645B (zh) * | 2013-08-30 | 2016-08-10 | 北京中联康生物科技股份有限公司 | 伪狂犬病毒、伪狂犬病疫苗及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9106879A (pt) * | 1990-09-25 | 1993-07-20 | Cantab Pharma Res | Virus mutuante nao retroviral,uso do mesmo,vacina e processo de manufaturar umvirus mutante |
US5240703A (en) * | 1991-03-01 | 1993-08-31 | Syntro Corporation | Attenuated, genetically-engineered pseudorabies virus s-prv-155 and uses thereof |
-
1993
- 1993-06-28 AU AU45606/93A patent/AU4560693A/en not_active Abandoned
- 1993-06-28 JP JP6504922A patent/JPH07500972A/ja not_active Ceased
- 1993-06-28 US US08/211,278 patent/US5626850A/en not_active Expired - Fee Related
- 1993-06-28 DE DE1993633751 patent/DE69333751T2/de not_active Expired - Fee Related
- 1993-06-28 EP EP93915729A patent/EP0606437B1/de not_active Expired - Lifetime
- 1993-06-28 WO PCT/EP1993/001661 patent/WO1994003595A1/en active IP Right Grant
- 1993-06-28 AT AT93915729T patent/ATE288483T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0606437A1 (de) | 1994-07-20 |
WO1994003595A1 (en) | 1994-02-17 |
DE69333751T2 (de) | 2005-12-29 |
JPH07500972A (ja) | 1995-02-02 |
ATE288483T1 (de) | 2005-02-15 |
US5626850A (en) | 1997-05-06 |
AU4560693A (en) | 1994-03-03 |
EP0606437B1 (de) | 2005-02-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69333751D1 (de) | Nicht-verbreitendes lebendes herpesvirusvakzin | |
Bagust et al. | Avian infectious laryngotracheitis: Virus‐host interactions in relation to prospects for eradication | |
TW289731B (de) | ||
NO933260L (no) | Rekombinante virusvektorer kodende for humane papillomavirus proteiner | |
Martin et al. | Mechanisms of antiviral immunity induced by a vaccinia virus recombinant expressing herpes simplex virus type 1 glycoprotein D: cytotoxic T cells | |
BR9708387A (pt) | Processo para vacinação de um mamìfero a um antìgeno selecionado, células patogênica e hospedeira, composição de vacina, ácido nucleico, e, opsonina engenheirada. | |
ES8505719A1 (es) | Procedimiento de preparar mutantes de delecion vivos y metodo de preparar vacunas | |
DE69806408D1 (de) | Rekombinante impfstoffe die immunogene attenuierte rpos-positiv phentotyp bakterien enthalten | |
Herberman | Immunogenicity of tumor antigens | |
ATE432085T1 (de) | Stimulationsfaktor für dendriten | |
ATE239036T1 (de) | Rekombinantes core-streptavidin | |
CA2269754A1 (en) | Dna vaccines for herpes simplex virus 1 and 2 | |
IL77694A (en) | Canine parvovirus vaccines comprising viruses of the canine parvovirus strain 154 or viruses derived therefrom by additional cell culture passaging | |
IL103144A0 (en) | Method of controlling lepidopteran pests | |
HUP0102861A2 (hu) | Attenuált lóherpeszvírus | |
PT854914E (pt) | Vacinas vivas contra agentes patogenicos gram-negativos expressando o-antigenes heterologos | |
DE69332264D1 (de) | Mutanten des infektiösen rinder rhinotracheitis-virus und impfstoffe | |
YU49995A (sh) | Polinukleotidna vakcina za virus herpesa | |
Hill | The immune response to CMV infection and vaccination in mice, monkeys and humans: recent developments | |
ATE178654T1 (de) | Impstoff zum schutze von pferden gegen pferdeherpesvirus-infektionen | |
ATE263837T1 (de) | Expressionsteigerung durch gentargeting in endogene retrovirus-ähnliche sequenzen | |
AU1853995A (en) | Vaccine compositions | |
ES2074965A1 (es) | Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen. | |
ES2140336B1 (es) | Mutantes no virulentos de brucella abortus. | |
Grabstein et al. | Regulation of Murine B-Cell Growth in Vitro by Infection with a Retroviral Vector Containing the Murine IL-1R |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee | ||
8364 | No opposition during term of opposition |