DK0651743T3 - Indolinyl-N-hydroxyurinstof- og N-hydroxamsyrederivater som lipoxygenaseinhibitorer - Google Patents

Indolinyl-N-hydroxyurinstof- og N-hydroxamsyrederivater som lipoxygenaseinhibitorer

Info

Publication number
DK0651743T3
DK0651743T3 DK93915230.2T DK93915230T DK0651743T3 DK 0651743 T3 DK0651743 T3 DK 0651743T3 DK 93915230 T DK93915230 T DK 93915230T DK 0651743 T3 DK0651743 T3 DK 0651743T3
Authority
DK
Denmark
Prior art keywords
alkyl
aryl
halosubstituted
alkoxy
independently
Prior art date
Application number
DK93915230.2T
Other languages
Danish (da)
English (en)
Inventor
Takafumi Ikeda
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0651743T3 publication Critical patent/DK0651743T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK93915230.2T 1992-07-23 1993-06-10 Indolinyl-N-hydroxyurinstof- og N-hydroxamsyrederivater som lipoxygenaseinhibitorer DK0651743T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4197242A JP2661841B2 (ja) 1992-07-23 1992-07-23 インドリン誘導体

Publications (1)

Publication Number Publication Date
DK0651743T3 true DK0651743T3 (da) 1998-02-02

Family

ID=16371216

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93915230.2T DK0651743T3 (da) 1992-07-23 1993-06-10 Indolinyl-N-hydroxyurinstof- og N-hydroxamsyrederivater som lipoxygenaseinhibitorer

Country Status (24)

Country Link
EP (1) EP0651743B1 (fr)
JP (1) JP2661841B2 (fr)
KR (1) KR950702533A (fr)
CN (1) CN1085894A (fr)
AT (1) ATE161250T1 (fr)
AU (1) AU675654B2 (fr)
BR (1) BR9306762A (fr)
CA (1) CA2140344C (fr)
CZ (1) CZ15995A3 (fr)
DE (1) DE69315841T2 (fr)
DK (1) DK0651743T3 (fr)
ES (1) ES2110101T3 (fr)
FI (1) FI104068B1 (fr)
GR (1) GR3025809T3 (fr)
HU (1) HUT70182A (fr)
IL (1) IL106359A0 (fr)
MX (1) MX9304441A (fr)
NZ (1) NZ253881A (fr)
PL (1) PL307229A1 (fr)
SK (1) SK8695A3 (fr)
TW (1) TW227556B (fr)
WO (1) WO1994002459A1 (fr)
YU (1) YU50893A (fr)
ZA (1) ZA935304B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992006573A1 (fr) * 1990-10-02 1992-04-16 Stat-Tech International Corporation Dispositif servant a dissiper et a decharger une charge electrique
AU4400597A (en) * 1996-10-08 1998-05-05 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
US5952322A (en) * 1996-12-05 1999-09-14 Pfizer Inc. Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors
WO2000003703A1 (fr) * 1998-07-17 2000-01-27 Fuji Yakuhin Kogyo Kabushiki Kaisha Medicaments contre les maladies allergiques
CA2408913A1 (fr) * 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Antagoniste de l'hormone de concentration de la melanine
UA95084C2 (en) * 2005-11-04 2011-07-11 Амира Фармасутикалз, Инк. 5-lipoxygenase-activating protein (flap) inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3882732T2 (de) * 1987-02-10 1993-12-02 Abbott Lab Indol, Benzofuran, Benzothiophen enthaltende, Lipoxygenase hemmende Verbindungen.
IE903206A1 (en) * 1989-09-07 1991-03-13 Abbott Lab Indole-, benzofuran-, and benzothiophene-containing¹lipoxygenase-inhibiting compounds
KR900016822A (ko) * 1990-04-20 1990-11-14 하라 레이노스께 슬라이드 프로젝터
US5132319A (en) * 1991-03-28 1992-07-21 Merck Frosst Canada, Inc. 1-(hydroxylaminoalkyl) indole derivatives as inhibitors of leukotriene biosynthesis

Also Published As

Publication number Publication date
ZA935304B (en) 1995-01-23
FI104068B (fi) 1999-11-15
JPH0641068A (ja) 1994-02-15
FI104068B1 (fi) 1999-11-15
GR3025809T3 (en) 1998-03-31
PL307229A1 (en) 1995-05-15
NZ253881A (en) 1996-01-26
AU4529193A (en) 1994-02-14
TW227556B (fr) 1994-08-01
WO1994002459A1 (fr) 1994-02-03
EP0651743A1 (fr) 1995-05-10
CA2140344A1 (fr) 1994-02-03
SK8695A3 (en) 1995-07-11
YU50893A (sh) 1996-07-24
FI933307A0 (fi) 1993-07-22
CZ15995A3 (en) 1995-09-13
MX9304441A (es) 1994-07-29
ATE161250T1 (de) 1998-01-15
IL106359A0 (en) 1993-11-15
EP0651743B1 (fr) 1997-12-17
DE69315841T2 (de) 1998-04-09
HUT70182A (en) 1995-09-28
CA2140344C (fr) 1997-08-26
AU675654B2 (en) 1997-02-13
KR950702533A (ko) 1995-07-29
DE69315841D1 (de) 1998-01-29
JP2661841B2 (ja) 1997-10-08
CN1085894A (zh) 1994-04-27
ES2110101T3 (es) 1998-02-01
BR9306762A (pt) 1998-12-08
FI933307A (fi) 1994-01-24
HU9302126D0 (en) 1993-10-28

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