KR950702533A - 리폭시게나제 억제제로서의 인돌리닐 n-하이드록시우레아 및 n-하이드록삼산 유도체(indolinyl n-hydroxyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors) - Google Patents

리폭시게나제 억제제로서의 인돌리닐 n-하이드록시우레아 및 n-하이드록삼산 유도체(indolinyl n-hydroxyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors)

Info

Publication number
KR950702533A
KR950702533A KR1019940700233A KR19940700233A KR950702533A KR 950702533 A KR950702533 A KR 950702533A KR 1019940700233 A KR1019940700233 A KR 1019940700233A KR 19940700233 A KR19940700233 A KR 19940700233A KR 950702533 A KR950702533 A KR 950702533A
Authority
KR
South Korea
Prior art keywords
alkyl
indolinyl
hydroxyurea
acid derivatives
aryl
Prior art date
Application number
KR1019940700233A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR950702533A publication Critical patent/KR950702533A/ko

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019940700233A 1992-07-23 1994-01-25 리폭시게나제 억제제로서의 인돌리닐 n-하이드록시우레아 및 n-하이드록삼산 유도체(indolinyl n-hydroxyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors) KR950702533A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4197242A JP2661841B2 (ja) 1992-07-23 1992-07-23 インドリン誘導体
PCT/US1993/005391 WO1994002459A1 (en) 1992-07-23 1993-06-10 Indolinyl n-hydrozyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors

Publications (1)

Publication Number Publication Date
KR950702533A true KR950702533A (ko) 1995-07-29

Family

ID=16371216

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940700233A KR950702533A (ko) 1992-07-23 1994-01-25 리폭시게나제 억제제로서의 인돌리닐 n-하이드록시우레아 및 n-하이드록삼산 유도체(indolinyl n-hydroxyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors)

Country Status (24)

Country Link
EP (1) EP0651743B1 (ko)
JP (1) JP2661841B2 (ko)
KR (1) KR950702533A (ko)
CN (1) CN1085894A (ko)
AT (1) ATE161250T1 (ko)
AU (1) AU675654B2 (ko)
BR (1) BR9306762A (ko)
CA (1) CA2140344C (ko)
CZ (1) CZ15995A3 (ko)
DE (1) DE69315841T2 (ko)
DK (1) DK0651743T3 (ko)
ES (1) ES2110101T3 (ko)
FI (1) FI104068B1 (ko)
GR (1) GR3025809T3 (ko)
HU (1) HUT70182A (ko)
IL (1) IL106359A0 (ko)
MX (1) MX9304441A (ko)
NZ (1) NZ253881A (ko)
PL (1) PL307229A1 (ko)
SK (1) SK8695A3 (ko)
TW (1) TW227556B (ko)
WO (1) WO1994002459A1 (ko)
YU (1) YU50893A (ko)
ZA (1) ZA935304B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8870191A (en) * 1990-10-02 1992-04-28 Stat-Tech International Corporation Electric charge discharge and dissipation device
AU4400597A (en) * 1996-10-08 1998-05-05 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
US5952322A (en) * 1996-12-05 1999-09-14 Pfizer Inc. Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors
EP1101492A4 (en) * 1998-07-17 2002-09-25 Daiichi Fine Chem Co Ltd MEDICINE AGAINST ALLERGIC DISEASES
EP1283199A4 (en) * 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd MELANIN CONCENTRATION HORMONE ANTAGONIST
UA95084C2 (en) * 2005-11-04 2011-07-11 Амира Фармасутикалз, Инк. 5-lipoxygenase-activating protein (flap) inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0279263B1 (en) * 1987-02-10 1993-08-04 Abbott Laboratories Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
IE903206A1 (en) * 1989-09-07 1991-03-13 Abbott Lab Indole-, benzofuran-, and benzothiophene-containing¹lipoxygenase-inhibiting compounds
KR900016822A (ko) * 1990-04-20 1990-11-14 하라 레이노스께 슬라이드 프로젝터
US5132319A (en) * 1991-03-28 1992-07-21 Merck Frosst Canada, Inc. 1-(hydroxylaminoalkyl) indole derivatives as inhibitors of leukotriene biosynthesis

Also Published As

Publication number Publication date
NZ253881A (en) 1996-01-26
PL307229A1 (en) 1995-05-15
BR9306762A (pt) 1998-12-08
ATE161250T1 (de) 1998-01-15
FI933307A (fi) 1994-01-24
HU9302126D0 (en) 1993-10-28
HUT70182A (en) 1995-09-28
EP0651743A1 (en) 1995-05-10
FI104068B (fi) 1999-11-15
YU50893A (sh) 1996-07-24
DK0651743T3 (da) 1998-02-02
GR3025809T3 (en) 1998-03-31
FI104068B1 (fi) 1999-11-15
CA2140344C (en) 1997-08-26
AU675654B2 (en) 1997-02-13
CA2140344A1 (en) 1994-02-03
WO1994002459A1 (en) 1994-02-03
CN1085894A (zh) 1994-04-27
ZA935304B (en) 1995-01-23
MX9304441A (es) 1994-07-29
JPH0641068A (ja) 1994-02-15
DE69315841D1 (de) 1998-01-29
ES2110101T3 (es) 1998-02-01
EP0651743B1 (en) 1997-12-17
IL106359A0 (en) 1993-11-15
DE69315841T2 (de) 1998-04-09
AU4529193A (en) 1994-02-14
TW227556B (ko) 1994-08-01
CZ15995A3 (en) 1995-09-13
JP2661841B2 (ja) 1997-10-08
FI933307A0 (fi) 1993-07-22
SK8695A3 (en) 1995-07-11

Similar Documents

Publication Publication Date Title
DK0862567T3 (da) 5-azabicyclo[3.1.0]hexylalkyl-2-piperidoner og-glutarimider som neurokininreceptorantagonister
NO20015446D0 (no) Kinolin-derivater som inhibitorer for MEK-enzymer
KR950702533A (ko) 리폭시게나제 억제제로서의 인돌리닐 n-하이드록시우레아 및 n-하이드록삼산 유도체(indolinyl n-hydroxyurea and n-hydroxamic acid derivatives as lipoxygenase inhibitors)
ATE113942T1 (de) Lipoxygenase inhibierende hydroxamsäure und n- hydroxyharnstoff-derivate.
ATE167180T1 (de) Cycloalkylhydroxyharnstoffe und ihre verwendung als lipoxy-genase-inhibitoren
ATE215075T1 (de) Hydroxylamin-derivate mit anti-ischämischer wirkung und pharmazeutische zusammensetzungen diese enthaltend
ATE132857T1 (de) Lipoxygenase inhibierende tetrahydrobenzazepinderivate
DK0588850T3 (da) N-hydroxyureaderivater, som inhiberer lipoxygenase
NO20004679L (no) Farmasøytisk sammensetning inneholdende en cystein- proteasehemmer for forebygging og terapi av hjernevevsforringelse

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid