DK0636602T3 - Fremgangsmåde til fremstilling af diacerein - Google Patents

Fremgangsmåde til fremstilling af diacerein

Info

Publication number
DK0636602T3
DK0636602T3 DK94110551T DK94110551T DK0636602T3 DK 0636602 T3 DK0636602 T3 DK 0636602T3 DK 94110551 T DK94110551 T DK 94110551T DK 94110551 T DK94110551 T DK 94110551T DK 0636602 T3 DK0636602 T3 DK 0636602T3
Authority
DK
Denmark
Prior art keywords
diacerein
preparation
carboxyanthraquinone
aloin
diacetoxy
Prior art date
Application number
DK94110551T
Other languages
Danish (da)
English (en)
Inventor
Napoli Guido Di
Original Assignee
Medidom Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27543486&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0636602(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medidom Lab filed Critical Medidom Lab
Application granted granted Critical
Publication of DK0636602T3 publication Critical patent/DK0636602T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/293—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK94110551T 1993-07-30 1994-07-07 Fremgangsmåde til fremstilling af diacerein DK0636602T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IT93MI001741A IT1264545B1 (it) 1993-07-30 1993-07-30 Procedimento per la preparazione della diacereina
CZ199590A CZ286702B6 (en) 1993-07-30 1995-01-12 Process for preparing diacerein
SK44-95A SK281699B6 (sk) 1993-07-30 1995-01-12 Spôsob prípravy diacereínu
HU9500188A HU221980B1 (hu) 1993-07-30 1995-01-23 Eljárás diacerein előállítására és új acilezett aloin intermedier
US08/376,722 US5670695A (en) 1993-07-30 1995-01-23 Process for the preparation of diacerein
CA002141247A CA2141247C (en) 1993-07-30 1995-01-27 Process for the preparation of diacerein

Publications (1)

Publication Number Publication Date
DK0636602T3 true DK0636602T3 (da) 1999-01-11

Family

ID=27543486

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94110551T DK0636602T3 (da) 1993-07-30 1994-07-07 Fremgangsmåde til fremstilling af diacerein

Country Status (12)

Country Link
US (1) US5670695A (de)
EP (1) EP0636602B1 (de)
JP (1) JP3850458B2 (de)
AT (1) ATE165335T1 (de)
CA (1) CA2141247C (de)
CZ (1) CZ286702B6 (de)
DE (1) DE69409722T2 (de)
DK (1) DK0636602T3 (de)
ES (1) ES2115814T3 (de)
HU (1) HU221980B1 (de)
IT (1) IT1264545B1 (de)
SK (1) SK281699B6 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH689279A5 (fr) * 1995-02-07 1999-01-29 Steba Beheer Bv Procédé de purification de la diacétylrhéine.
IT1283772B1 (it) * 1996-07-31 1998-04-30 Medidom Lab Procedimento per la preparazione di reina e diacereina
IT1283771B1 (it) * 1996-07-31 1998-04-30 Medidom Lab Procedimento per la preparazione di derivati della reina
IT1292132B1 (it) * 1997-06-11 1999-01-25 Synteco S R L Procedimento per la preparazione di diacereina
IT1297038B1 (it) * 1997-12-30 1999-08-03 Medidom Lab Procedimento per la preparazione di reina e suoi diacilderivati
US20070141181A1 (en) 1998-02-13 2007-06-21 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US6797289B2 (en) 1998-02-13 2004-09-28 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US6451771B1 (en) 1999-02-12 2002-09-17 Nutramax Laboratories, Inc. Use of anabolic agents anti-catabolic agents and antioxidant agents for protection treatment and repair of connective tissues in humans and animals
IT1312309B1 (it) * 1999-05-07 2002-04-15 Synteco Spa Procedimento per la purificazione di diacereina
AR026801A1 (es) 2000-01-12 2003-02-26 Medidom Lab Sustancias para uso en el tratamiento de la psoriasis
IT1318574B1 (it) * 2000-06-13 2003-08-27 Synteco Spa Procedimento per la purificazione di diacereina.
ITMI20022535A1 (it) * 2002-11-29 2004-05-30 Synteco Spa Procedimento per la purificazione della diacereina.
EP2060562A1 (de) 2007-11-16 2009-05-20 Laboratoire Medidom S.A. Dioxoanthracen-Sulfonat-Derivate
WO2009106908A1 (en) 2008-02-29 2009-09-03 Laboratoire Medidom S.A. Process for preparing rhein
WO2009106909A1 (en) * 2008-02-29 2009-09-03 Laboratoire Medidom S.A. Process for the purification of diacerein
WO2011030350A1 (en) 2009-09-08 2011-03-17 Lupin Limited Eco-friendly method for catalytic aerial oxidation of aloe-emodin to rheinal
CN101696164A (zh) * 2009-10-19 2010-04-21 黄再新 一步法用芦荟甙合成双醋瑞因粗品的方法
ITTO20110120A1 (it) 2011-02-11 2012-08-12 Icrom Spa Un nuovo processo di purificazione per derivati antrachinonici
CN104774150B (zh) * 2014-01-14 2017-04-12 北京万生药业有限责任公司 一种双醋瑞因晶体及其制备方法
CN112279767B (zh) * 2020-10-29 2023-02-03 陕西嘉禾生物科技股份有限公司 一种双醋瑞因的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761627B (en) * 1976-03-16 1978-01-25 C Friedmann Improvements in or relating to the treatment of arthritis
IT1189097B (it) * 1986-05-02 1988-01-28 Proter Spa Sali di diacetilreina e loro impiego terapeutico nel trattamento dell'artrosi
DE4120989C2 (de) * 1991-06-25 1995-07-27 Madaus Ag Verfahren zur Herstellung von Diacetylrhein
US5393898A (en) * 1991-06-25 1995-02-28 Madaus Ag Method of preparing diacetyl rhein

Also Published As

Publication number Publication date
CA2141247A1 (en) 1996-07-28
CZ9095A3 (en) 1996-07-17
HU221980B1 (hu) 2003-03-28
US5670695A (en) 1997-09-23
EP0636602A1 (de) 1995-02-01
EP0636602B1 (de) 1998-04-22
CZ286702B6 (en) 2000-06-14
HUT73498A (en) 1996-08-28
ITMI931741A1 (it) 1995-01-30
ATE165335T1 (de) 1998-05-15
CA2141247C (en) 2004-08-31
JP3850458B2 (ja) 2006-11-29
ES2115814T3 (es) 1998-07-01
JPH0753462A (ja) 1995-02-28
DE69409722T2 (de) 1998-08-13
SK4495A3 (en) 1996-08-07
DE69409722D1 (de) 1998-05-28
HU9500188D0 (en) 1995-03-28
SK281699B6 (sk) 2001-07-10
ITMI931741A0 (it) 1993-07-30
IT1264545B1 (it) 1996-10-02

Similar Documents

Publication Publication Date Title
DK0636602T3 (da) Fremgangsmåde til fremstilling af diacerein
DE69104280D1 (de) Verfahren zur Herstellung von hochreiner Isophthalsäure.
DE69619030T2 (de) Verfahren zur Herstellung von Essigsäure durch Carbonylierung
DE69203959D1 (de) Verfahren zur Herstellung von Prepregs.
DK0417829T4 (da) Fremgangsmåde til rensning af effluenten fra urinstofproduktionsanlæg
DE69224562T2 (de) Verfahren zur Herstellung von Stabstahl zum Kaltbearbeiten
DE69102101D1 (de) Verfahren zur Herstellung von hochreinen Kathoden auf Aluminiumbasis für Kathodenzerstäubung.
DE69415722D1 (de) Verfahren zur Herstellung von Polycarbonaten
DE69122936D1 (de) Verfahren zur Herstellung von Sialsäure
DE3891468T1 (de) Aethylester der 6-brom-5-hydroxy-4-dimethylaminomethyl-1-methyl-2-phenylthiomethylindol-3-karbonsaeure des monohydrat-hydrogenchlorids, verfahren zu seiner herstellung und arzneipraeparat mit antiviraler, interferoniduzierender und immunomodulierender wirkung auf seiner grundlage
DE59002817D1 (de) Verfahren zur kontinuierlichen Reinigung von Caprolactam.
DE69609993D1 (de) Calixarene und ihre verwendung für das abtrennen von metallen
ATE108171T1 (de) Reinigung von 1,1-dichlor-1-fluorethan.
DE69105615D1 (de) Verfahren zur Herstellung von hochreiner Isophthalsäure.
DE59010896D1 (de) Verfahren zur Herstellung von 7-(3-Amino- sowie 3-Aminomethyl-1-pyrrolidinyl)-3-chinolon-carbonsäuren sowie -naphthyridoncarbonsäuren
DE69331256T2 (de) Verfahren zur Herstellung von Chlorogalliumphtalocyaninkristallen
DE69424899T2 (de) Verfahren zur Herstellung von Essigsäure
DE69008201D1 (de) Verfahren zur Beseitigung von organischen Chlorverbindungen durch Verbrennung.
DE59601070D1 (de) Verfahren zur Reinigung von N-Vinylpyrrolidon durch Kristallisation
FR2694001B1 (fr) Procédé de synthèse d'acide chloracétique dans lequel on purifie l'acide chlorhydrique sous produit.
DE59101013D1 (de) Verfahren zur Trennung von m- und p-Dichlorbenzol.
DE69425011D1 (de) Verfahren zur Herstellung von Polyketonen
DE59409759D1 (de) Entfärbung von Fermentationslösungen
ATE133650T1 (de) Verfahren und reinigung von essigsäureanhydrid und essigsäure
DE69417997D1 (de) Auf Uretoniminzusammensetzungen basierende Polyurethanteile und Verfahren zu ihrer Herstellung